Applied Organometallic Chemistry最新文献

{"title":"Electrochemical Sensing of Propofol Using a Flexible Electrode Modified With Au@Co-Metal–Organic Framework","authors":"Yinan Yang,&nbsp;Shouhui Chen,&nbsp;Dan Zhou,&nbsp;Qinghao Xiong,&nbsp;Bingxian Peng","doi":"10.1002/aoc.70373","DOIUrl":"https://doi.org/10.1002/aoc.70373","url":null,"abstract":"<div>\u0000 \u0000 <p>Propofol, an intravenous anesthetic, is widely used for general anesthesia and sedation during surgical procedures. It is necessary to detect the blood propofol concentration due to its rapid metabolism in the body. In this work, we develop a flexible electrochemical propofol sensor by integrating gold nanoparticles (AuNPs) with cobalt metal–organic frameworks (Co-MOF) on carbon cloth (CC). The sensor leverages the synergistic effects of CC's large surface area, Co-MOF's catalytic activity, and AuNPs' conductivity to achieve highly sensitive and selective detection of propofol. The experimental conditions for the propofol sensor, including AuNP deposition time and pH, were systematically optimized, yielding a broad linear detection range of 0.159~260 μM and an ultralow detection limit of 0.0522 μM. The propofol sensor also demonstrates excellent selectivity, reproducibility, and stability. The practical application of the sensor is validated through the analysis of human serum samples, indicating its potential clinical application.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Rutin-Based AIE Probes With Enhanced Fe3+ Recognition via Hydroxyl Group Engineering","authors":"Kai Wang,&nbsp;Peiwen Lv,&nbsp;Mingyang Liu,&nbsp;Yunjun Mei,&nbsp;Yifan Zhang,&nbsp;Yuqiu Zheng,&nbsp;Jintao Guan","doi":"10.1002/aoc.70368","DOIUrl":"https://doi.org/10.1002/aoc.70368","url":null,"abstract":"<div>\u0000 \u0000 <p>Traditional fluorescent probes have challenges, including aggregation-induced quenching, biological incompatibility, and suboptimal selectivity. In this study, we developed a novel probe derived from natural rutin featuring an aggregation-induced emission (AIE) effect. Through hydroxy engineering of rutin, the optimized probe enables precise detection of Fe³⁺ via 2:1 stoichiometric coordination. The probe demonstrates remarkable analytical performance, with a detection limit as low as 0.22 μM. Concentration-dependent responses were observed within 0–20 μM, with significant linearity (<i>R</i>² &gt; 0.99) in the 0–10 μM range. Density functional theory calculations reveal that the binding of Fe³⁺ effectively suppresses intramolecular charge transfer. The hydroxy-engineered modification plays a pivotal role in facilitating complexation for bond formation and providing appropriate steric hindrance. This research establishes a new benchmark for natural product-based AIE probes and deepens understanding of the structure–activity relationships governing flavonoid-metal recognition.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesis of Silver Nanoparticles Using Justicia adhatoda Leaf Extract: Characterization and Nonlinear Optical Applications","authors":"K. Priyadharsini Karthikeyan,&nbsp;A. G. Bharathi Dileepan,&nbsp;G. Murali,&nbsp;Natarajan Arumugam,&nbsp;Abdulrahman I. Almansour,&nbsp;Madhappan Santhamoorthy,&nbsp;S. Jeyaram","doi":"10.1002/aoc.70367","DOIUrl":"https://doi.org/10.1002/aoc.70367","url":null,"abstract":"<div>\u0000 \u0000 <p>This study reports the synthesis of silver nanoparticles (AgNPs) using leaf extract of <i>Justicia adhatoda</i>. This green and eco-friendly method produces highly stable AgNPs, which are characterized using various techniques, including UV–visible absorbance, FT-IR, XRD, FESEM, and TEM. A strong surface plasmon resonance (SPR) is observed at a wavelength of 411 nm. The functional groups present in the AgNPs are identified using FT-IR, revealing a peak at 456 cm⁻¹ corresponding to Ag⁺ bond vibration. The crystalline properties of AgNPs are examined via XRD, with an average crystal size measured at 23.33 nm. Moreover, FESEM and TEM studies revealed that the nanoparticles possess a spherical shape. The Z-scan technique is employed at a wavelength of 405 nm to investigate the third-order nonlinear optical (NLO) responses of AgNPs. The nonlinear refractive index (<i>n</i>₂) and nonlinear absorption coefficient (<i>β</i>) are attributed to self-defocusing and reverse saturable absorption (RSA) processes. A significant third-order NLO susceptibility is measured, estimated to be in the order of 10⁻⁷ esu. Overall, the experimental results clearly indicate that the green synthesis of AgNPs using the leaf extract of <i>Justicia adhatoda</i> represents a promising material for NLO applications.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144843403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Optimal Analytical Techniques and Computational Approaches for Investigating Toxic Elements and Compounds in Pyrotechnic Materials (Green Crackers)","authors":"Darpan Dubey,&nbsp;Amit Dubey,&nbsp;Aisha Tufail,&nbsp;Awadhesh Kumar Rai","doi":"10.1002/aoc.70361","DOIUrl":"https://doi.org/10.1002/aoc.70361","url":null,"abstract":"<div>\u0000 \u0000 <p>This study presents a comprehensive analysis of green crackers using <b>laser-induced breakdown spectroscopy (LIBS), photoacoustic spectroscopy (PAS), and UV–visible (UV–Vis) techniques</b> to evaluate their elemental composition and environmental impact. The LIBS spectra identified elemental signatures of <b>Al, Ba, Sr, Cr, and Cu</b>, along with diatomic molecular bands (AlO, SrO, and CaO), corroborated by PAS and UV–Vis spectroscopy. Additionally, PAS spectra confirmed the presence of <b>KNO₃, NH₄NO₃, and NH₄ClO₄</b>. The quantification of heavy elements such as Al, Cr, and Cu was performed using <b>atomic absorption spectroscopy (AAS)</b>. To classify different green cracker types, <b>principal component analysis (PCA)</b> was employed on the LIBS dataset. Furthermore, <b>molecular docking simulations (MDS) and Density Functional Theory (DFT)</b> were used to assess the chemical reactivity of toxic molecules and their potential interaction with lung cancer and asthma-related proteins. The toxicity predictions were further refined using absorption, distribution, metabolism, excretion, and toxicity (<b>ADMET</b>) analysis. This study offers critical insights into the safety of green crackers, integrating experimental and computational approaches to evaluate their environmental and biological impact.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient Application of Supramolecular Behavior in the Antimicrobial Activity and Antioxidant of Structurally Mismatched Zn and Co-MOFs","authors":"Zi-hang Yuan,&nbsp;Si-ya Zheng,&nbsp;Yu-mei Dai,&nbsp;En Tang","doi":"10.1002/aoc.70363","DOIUrl":"https://doi.org/10.1002/aoc.70363","url":null,"abstract":"<div>\u0000 \u0000 <p>The escalating global challenges posed by antibiotic resistance and oxidative stress demand the urgent development of dual-functional materials integrating both antimicrobial and antioxidant capacities to address these intertwined biological threats. This raises a pivotal question: Why not engineer a material capable of simultaneously delivering antioxidant and antibacterial functionalities? To bridge this critical gap, we strategically designed two novel Co and Zn metal–organic frameworks (MOFs) through supramolecular interactions to achieve synergistic antimicrobial–antioxidant performance, rigorously validated via multimodal characterization. Different from traditional antibiotics, these MOFs exert antibacterial effects by controlling the release of metal ions and other mechanisms. Co and Zn-MOFs demonstrated robust antimicrobial efficacy against both Gram-negative and Gram-positive bacteria, coupled with potent antioxidant properties. Zn-MOFs exhibited enhanced antibacterial activity by intensifying membrane disruption via strengthened hydrophobic interactions with bacterial surfaces, whereas Co-MOFs showcased superior antioxidant capacity derived from their redox-active nature. This study unravels the critical mechanistic interplay between metal-bacteria interfacial dynamics and the preservation of cell wall structural integrity. These MOFs redefine multifunctional material paradigms for combating drug-resistant pathogens and oxidative damage, offering transformative potential for biomedical innovations and beyond.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144832886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Aortic and Cardiac Injury Following Sepsis by Curcumin Green-Formulated Silver Nanoparticles","authors":"Qing Li","doi":"10.1002/aoc.70349","DOIUrl":"https://doi.org/10.1002/aoc.70349","url":null,"abstract":"<div>\u0000 \u0000 <p>The main secondary metabolite of turmeric is a polyphenol molecule called curcumin. According to Chinese traditional medicine, the chemical offers a number of advantages. Nevertheless, no research has examined the possible advantages of its nanoparticles in reducing sepsis-induced cardiac and aortic damage thus far. Therefore, the purpose of this work was to examine how oxidative stress markers and nitric oxide (NO) are affected by silver nanoparticles green-formulated by curcumin in sepsis-induced aortic and cardiac damage. This study characterizes and synthesizes silver nanoparticles using green formulation techniques. Several spectroscopic techniques were used to analyze the silver nanoparticles, and their ability to cure sepsis-induced cardiac and aortic damage was also investigated. Adult male Wistar rats were classified into four groups for the in vivo design: control, lipopolysaccharide, and silver nanoparticles (50 and 200 μg/kg, oral). For 14 days, lipopolysaccharide (LPS) was injected every day. Silver nanoparticle therapy began 3 days before the delivery of LPS and continued during the administration of LPS. Antioxidant enzyme, thiols, NO, and malondialdehyde (MDA) levels were assessed after the research. The findings imply that silver nanoparticles can prevent cardiovascular damage caused by LPS by reducing NO generation and enhancing redox hemostasis. Our results demonstrated that the LPS group's levels of superoxide dismutase (SOD), thiols, and catalase (CAT) were significantly reduced; these levels were subsequently restored by silver nanoparticles. Silver nanoparticles also reduced NO and MDA levels in the cardiac and aortic tissues of LPS-injected rats. The new nanoparticles might be utilized to repair human cardiac and aortic damage caused by sepsis following clinical trial research.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144832887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights Regarding the Sonodynamic Antibacterial Activity of CCM@ZIF-8 Nanocomposite","authors":"Jing Lv,&nbsp;Danni Wang,&nbsp;Dongjing Wang,&nbsp;Xiu Ning,&nbsp;Xiao Wang,&nbsp;Xiaoyang Xu,&nbsp;Xiaofang Wang,&nbsp;Bin Liu","doi":"10.1002/aoc.70365","DOIUrl":"https://doi.org/10.1002/aoc.70365","url":null,"abstract":"<div>\u0000 \u0000 <p>Pathogenic microorganisms pose a growing threat to public health, particularly in light of the escalating challenge of antibiotic resistance. Consequently, there is a pressing demand for the development of innovative antimicrobial strategies. In recent years, sonodynamic antimicrobial chemotherapy (SACT) has emerged as a promising approach. In this investigation, we engineered a nanoscale organic–inorganic hybrid sonosensitizer Curcumin@ZIF-8 (CCM@ZIF-8), which featured a large surface area, high porosity, and excellent sonodynamic activity. It was mainly reflected that, under ultrasonic irradiation, CCM@ZIF-8 not only reduced the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the three strains but also its bactericidal effect was significantly higher than that of the nonultrasound group. Furthermore, mechanistic studies revealed that its superior sonodynamic antibacterial performance was attributed to the comprehensive effect, such as boosting intracellular reactive oxygen species generation, enhancing bacterial uptake of CCM, consistently releasing CCM, disrupting bacterial biofilms, inducing protein leakage, and ultimately achieving bactericidal effects. These insights contribute to a deeper understanding of the potential mechanisms underlying SACT. In conclusion, this study presents a novel antimicrobial therapeutic strategy for combating infectious diseases.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complexation Features of Quinoxalyl-Hydrazone Ligand Towards Oxo-Zirconium (IV) and Oxo-Vanadium (IV) Ions for Biological Studies and Catalytic Oxidation of Alcohols","authors":"Mohamed Shaker S. Adam,&nbsp;Ahmed Desoky M. Mohamad,&nbsp;Mustafa J. Abdelmageed Abualreish,&nbsp;Omran A. Omran,&nbsp;Zakaria S. Bakhuraisa,&nbsp;Ahmed Khalil","doi":"10.1002/aoc.70347","DOIUrl":"https://doi.org/10.1002/aoc.70347","url":null,"abstract":"<div>\u0000 \u0000 <p>Due to the facile design and strong coordinating features of hydrazones, a condensation reaction of 3,4-dihydroquinoxaline-2-carbohydrazide with 2-hydroxybenzaldehyde yielding (HLqh) was implemented aiming to examine its coordination action towards two high valent oxide metals (ZrO²⁺ and VO²⁺ ions) to give two complexes (ZrOLqh·2H₂O and VOLqh, respectively). Their molecular structures were confirmed using appropriate spectroscopic approaches, as well as the elemental composition studies, magnetic characteristics, thermogravimetric investigation, and conductivity behaviors. For the biological approach, HLqh, ZrOLqh·2H₂O, and VOLqh displayed an inhibitive behavior on the proliferated progression of three prevalent fungal and bacterial series and on three considered cancer cell lines, which were studied concerning the influence of O=M^IV ion in ZrOLqh·2H2O and VOLqh in comparison to their unbonded ligand (HLqh) on their inhibitive action. The microbial and cancer examination was elucidated within the inhibiting zone areas in mm and the half-concentration of effectiveness in mM (<i>IC</i>₅₀). Investigating the critical impact of O=M^IV ion in ZrOLqh·2H2O and VOLqh on their interacting binding to ct-DNA, as confirmed by changes in viscosity/spectrophotometric characteristics, was established. The interacting capability of ct-DNA was confirmed by referring to the Gibbs free energy, binding constant, and chromism types. The biological results were supported by docking studies. For the assessment of the catalytic potential, both ZrOLqh·2H2O and VOLqh were addressed (homogeneously) in the redox transformation of BZ (benzyl alcohol) in the presence of an oxidant (hydrogen peroxide) at 358 K. Both catalysts demonstrated performed catalytic redox action towards the formation of benzaldehyde. The yield percentage of benzaldehyde (the selective product, BZO) catalyzed by ZrOLqh·2H2O and VOLqh was 80% after 5 h and 86% after 3 h, respectively. The verified reactivity for each catalyst was attributed to the effect of metal ion nature, which was supported by a proper mechanism.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Cage-Like NiWO4/NH2-UIO-66 Adsorbents: Synthesis, Design, and Performance Prediction Based on Sparrow Search Algorithm","authors":"Likai Deng,&nbsp;Shifa Wang,&nbsp;Yuanyuan Zhang,&nbsp;Xinmiao Yu,&nbsp;Jinjin Ding,&nbsp;Lei Hu,&nbsp;Huajing Gao,&nbsp;Hua Yang,&nbsp;Leiming Fang,&nbsp;Jagadeesha Angadi. V,&nbsp;Shoyebmohamad F. Shaikh,&nbsp;Mohd Ubaidullah","doi":"10.1002/aoc.70359","DOIUrl":"https://doi.org/10.1002/aoc.70359","url":null,"abstract":"<div>\u0000 \u0000 <p>The cage-like NiWO₄/NH₂-UIO-66 (NNU) adsorbent was prepared by a polyacrylamide gel method combined with a hydrothermal method and was used to adsorb dyes (Congo red, CR) and antibiotics (tetracycline hydrochloride (TC), oxytetracycline hydrochloride, chlortetracycline hydrochloride, and ciprofloxacin) in wastewater. The NNU adsorbents contain only the target component and have a cage structure, a large specific surface area, and high surface active sites, as well as high adsorption capacity. When the adsorbent content was 1 g/L, the initial CR concentration was 200 mg/L, T = 298.15 K, pH = 6, and the molar ratio of NH₂-UIO-66 was 60%, the adsorption percentage of the NNU adsorbent reached 82.5%. When the temperature was increased to T = 320 K, the adsorption percentage of the NNU adsorbent increased to 96.3%. The Redlich-Peterson model provides an accurate simulation of the adsorption capacity of the NNU adsorbents. The maximum adsorption capacity of the NNU adsorbents for the adsorption of CR dye was 192.3 mg/g. The cyclic stability test showed that the NNU adsorbent could maintain its high adsorption capacity after 5 cycles. The adsorption capacity of the NNU adsorbent can be predicted most effectively using the Sparrow search algorithm due to its simplicity, few control parameters, high accuracy, fast convergence, high search accuracy, and high stability. The room temperature adsorption mechanism confirmed that the adsorption of CR dye by NNU adsorbents was mainly based on electrostatic interaction, pore filling, dipole bond force, hydrogen bond, and ion exchange, while the adsorption of TC molecules was mainly based on pore filling and ion exchange. Although this strategy requires a large amount of data to perform performance prediction, it will provide new ideas and technical references for the development of new adsorbents.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Step Synthesis of Self-Assembled Flower Shape CuNi-MOF-Based Nanocomposite for Non-Enzymatic Electrochemical Sensing of Atrazine in Real Sample","authors":"Shital Jyotsna Sahoo,&nbsp;Bhismadev Mahananda,&nbsp;Jyotiraditya Samantaray,&nbsp;Jaspreet Singh,&nbsp;Priyabrat Dash","doi":"10.1002/aoc.70342","DOIUrl":"https://doi.org/10.1002/aoc.70342","url":null,"abstract":"<div>\u0000 \u0000 <p>Atrazine is a pesticide that belongs to the class of chlorotriazine and has been proven to cause severe damage to the human endocrine system in case of ingestion. With its harmful effect on animals, plants, and the environment, there is a need for the development of sensor platforms that will be effective in detecting atrazine's presence in an aquatic environment. Metal–organic frameworks (MOFs), as a class of very ordered crystalline materials, have been of great interest because of their potential applications in electrochemical sensors based on distinct chemical and physical properties such as extremely high porosity, large surface area, and easily modifiable structural features. Bimetallic systems, in particular, provide MOFs with improved functionalities required for efficient electrochemical sensing. A bimetallic CuNi MOF–based binary nanocomposite with nitrogen-doped 3-dimensional rGO (N-3DrGO) was designed and was used to fabricate a sensor on the indium tin oxide (ITO) electrode. Powder X-ray diffraction (PXRD), Fourier transform infrared (FTIR), Raman spectroscopy, field emission scanning electron microscope (FESEM), transmission electron microscope (TEM), and X-ray photoelectron spectroscopy (XPS) techniques were employed for the characterization of CuNi-MOF/N-3DrGO. Further, in atrazine sensing, cyclic voltammetry (CV) analysis and square wave voltammetry (SWV) showed a decrease in current due to the blocking of electron transfer between the electrode and electrolyte interface. Later, SWV analysis showed our designed sensor can sense at a very wide range of 0.5 to 150 ppb with a limit of detection (LOD) of 0.18 ppb. This sensor also exhibited superior selectivity in the presence of other interfering ions and pesticides, stability for up to 5 weeks, and reproducibility. Lastly, a real-time sensing approach was performed by taking water, which showed an average recovery of 99.385%.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144814895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}