Applied Organometallic Chemistry最新文献

{"title":"Byproduct-Free, One-Pot Synthesis of Ortho Hydroxy Aryl Assimilated Dihydropyrimidones Over-Engineered Sulfonated Graphene Oxide at Room Temperature","authors":"Sushil R. Mathapati,&nbsp;Mantosh B. Swami,&nbsp;Vijaykumar S. More,&nbsp;Ashutosh Pandey,&nbsp;Suman Kusuma,&nbsp;Arvind H. Jadhav","doi":"10.1002/aoc.70372","DOIUrl":"https://doi.org/10.1002/aoc.70372","url":null,"abstract":"<div>\u0000 \u0000 <p>Dihydropyrimidinones (DHPMs) are an important class of heterocyclic compounds that exhibit a wide range of biological activities. They serve as a key structural motif in pharmaceuticals and agrochemicals, making their efficient and sustainable synthesis highly desirable. The nucleophilic nature of hydroxy groups often alters the reaction pathway towards the formation of oxygen-bonded tetracyclic derivatives and lactonization by-products, which is a significant challenge for the synthesis of dihydropyrimidinone derivatives (DHPM) with ortho-hydroxy groups. In the present study, a highly promising and environmentally friendly protocol has been developed for the synthesis of DHPM derivatives using sulfonated graphene oxide (GO-HSO₃) as a metal-free heterogeneous catalyst. The reaction proceeded in ethanol at room temperature, rendering a sustainable and greener approach. The catalytic system efficiently facilitated the Biginelli reactions between ethyl acetoacetate, urea, and azo salicylaldehyde or salicylaldehyde, leading to the selective transformation of DHPMs with excellent yields (84–94%) and minimal byproducts. The superior catalytic activity of GO-HSO₃ is attributed to its abundant –SO₃H functional groups, which enhance the proton donation and reaction kinetics. This approach is a sustainable and practical method for DHPM synthesis due to its excellent yield, ease of execution, reusability of the catalyst, and adherence to green chemistry principles. Compared to conventional methods that yield an undesired side product, this approach ensures high selectivity and cleaner synthesis. The developed strategy not only aligns with the principle but also demonstrates the potential of sulfonated graphene oxides as a sustainable catalyst for organic transformations.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tri-Transition Metal-Substituted Lanthanum-Based Perovskite Formulation for Catalytic Application in AP","authors":"Taruna Likhariya,&nbsp;Pragnesh N. Dave","doi":"10.1002/aoc.70369","DOIUrl":"https://doi.org/10.1002/aoc.70369","url":null,"abstract":"<div>\u0000 \u0000 <p>Lanthanum-based tri-transition metal-based perovskite structure was synthesized LaMn_<i>x</i>Co_<i>y</i>Fe_<i>z</i>O₃(<i>x</i> + <i>y</i> + <i>z</i> = 1) in three different compositions. IR spectroscopy shows the existence of M-O bond peak. The XRD patterns of pure cubic phase show an average crystalline size of 11.7 nm. Raman study provides insights into the various modes of vibration within the perovskite structure. BET surface area of the calcined material was 15.5 m²/g. N₂ adsorption curve signifies the porous nature of the adsorbent material. Its catalytic behavior towards ammonium perchlorate (AP) was established by TGA analysis, which shows 84 °C, 81 °C, and 94 °C decrease in the DSC peak, DTG peak, and DTA peak decomposition temperature of AP. Artificial neural networks were applied to forecast the TG curves and activation energy values.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Ag/Vit B3-MOF: A Proficient and Sustainable Approach, Photocatalytic Activity, and Molecular Docking Validation as HIV Replication Inhibitor","authors":"Mahmoud Tarek,&nbsp;Gehad E. Said,&nbsp;Abdulrahman A. Almehizia,&nbsp;Mohamed A. Al-Omar,&nbsp;Ahmed M. Naglah,&nbsp;Tamer K. Khatab","doi":"10.1002/aoc.70375","DOIUrl":"https://doi.org/10.1002/aoc.70375","url":null,"abstract":"<div>\u0000 \u0000 <p>Ag-Vit B₃/MOF, or porous silver-based organic framework, was synthesized in this study via a one-step solvothermal process. The produced photocatalyst was thoroughly characterized using a variety of analytical methods, including FT-IR, UV–Vis, XRD, SEM, EDX, TEM, XPS, and BET analysis, in order to assess its crystal structure and shape. Under xenon lamp irradiation, the produced catalyst's photocatalytic activity was tested using alizarine red S dye (ARS), an organic pollutant. Measurements of photocatalytic activity suggest that the photocatalyst may effectively destroy the organic ARS dye. Photocatalysis might degrade 99% of the dye in 90 min. Ag-Vit B₃/MOF has a bandgap energy of 2.8 eV according to DFT and UV–vis spectrum studies. It has a conduction band (CB) potential of −4.69 eV and a valence band (VB) potential of −1.94 eV. Our findings demonstrate that the Ag-Vit B₃/MOF photocatalyst is an effective and sustainable photocatalyst for the in situ degradation of ARS dye from industrial wastewater, with the maximum photostability lasting up to five cycles. The Ag-Vit B₃/MOF complex was attached to the RNA at the HIV frameshift site and evaluated as a potential inhibitor of HIV replication. Compared to reference compounds such as dolutegravir and nevirapine, the Ag/Vit B₃-MOF exhibited strong binding affinity (E-score greater than − 10 kcal/mol). Additionally, the Ag-MOF showed promising interactions with both reverse transcriptase and integrase enzymes, suggesting its potential as a potent inhibitor of HIV replication.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and Synthesis of Novel Bio-MOF UTSA-16 (Zn) Catalyst for One-Pot Synthesis of 3,3-Di(indolyl)indolin-2-ones: Their Molecular Docking, Anti-Microbial, and Anti-Oxidant Evaluation","authors":"Akshay Gurav,&nbsp;Dipali Kuchekar,&nbsp;Lalit Bhosale,&nbsp;Prasad Swami,&nbsp;Prakash Chavan,&nbsp;Nisha Nerlekar,&nbsp;Padma Dandge,&nbsp;Praful Choudhari,&nbsp;Sneha Rochlani,&nbsp;Sandeep Sankpal,&nbsp;Shankar Hangirgekar","doi":"10.1002/aoc.70366","DOIUrl":"https://doi.org/10.1002/aoc.70366","url":null,"abstract":"<div>\u0000 \u0000 <p>This study explored the catalytic potential of the bio-MOF UTSA-16 (Zn) for the synthesis of novel 3,3-di (indolyl)indolin-2-ones through one-pot reactions between isatins and indoles. The present approach involved water as an eco-friendly solvent, and the hydrothermally synthesized bio-MOF UTSA-16 (Zn) catalyst has been comprehensively characterized by using XRD, SEM, EDX, TG-DTA, FT-IR, and BET analytical techniques. The UTSA-16 (Zn) MOF exhibited catalytic efficiency toward the candidates for 3,3-di (indolyl)indolin-2-one, which were fully characterized using ¹H and ¹³C NMR spectrometry. Furthermore, the catalyst demonstrated excellent reusability and stability, maintaining its catalytic performance across five successive cycles without significant loss of reactivity. Additionally, the in vitro antimicrobial activity of the synthesized 3,3-di (indolyl)indolin-2-one derivatives and reference drugs was evaluated against gram-negative and gram-positive bacteria, specifically <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>. Compounds <b>3b</b> and <b>3e</b> consistently demonstrated the most potent antimicrobial activity against <i>E. coli</i> and <i>S. aureus</i>, showing zones of inhibition of 6–7 mm and 15 mm at a concentration of 100 μg/mL. The DPPH assay indicated that Compound <b>3e</b> exhibited the most significant antioxidant activity, with an IC₅₀ value of 52.34 ± 0.20 μg/mL, reflecting its high efficacy in scavenging DPPH radicals. Moreover, molecular docking studies were conducted on the synthesized compounds, aligning with the in vitro results and supported by a structural activity relationship study. This protocol highlights several key advantages, including green solvent, operational simplicity, short reaction times, reusability, high product yields, and availability of high surface area of the UTSA-16 (Zn) catalyst.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Properties of Highly Efficient Luminescent Zn-Tb and Zn-Eu Multimetal Complexes","authors":"Quanfeng Ye,&nbsp;Lingyi Li,&nbsp;Jie Zhang,&nbsp;Mingyu Teng,&nbsp;Fengshou Wu,&nbsp;Deman Han","doi":"10.1002/aoc.70374","DOIUrl":"https://doi.org/10.1002/aoc.70374","url":null,"abstract":"<div>\u0000 \u0000 <p>Salen-type Schiff-base ligands (H₂L) were synthesized through the condensation reaction between 1,2-diphenylethane-1,2-diamine and o-vanillin. Three novel luminescent Zn-Ln complexes, [ZnL]₂Ln (Ln = Gd, Tb, Eu), were successfully prepared by reacting the zinc complex (ZnL) with LnCl₃. Subsequent treatment of [ZnL]₂Ln with dibenzoylmethane yielded three dinuclear derivatives, β-[ZnL]Ln (Ln = Gd, Tb, Eu). All complexes were comprehensively characterized by single-crystal X-ray diffraction and FT-IR spectroscopy. Structural analyses revealed that complexes 1–3 adopt trinuclear Zn-Ln-Zn architectures, whereas complexes 4–6 exhibit dinuclear Zn-Ln configurations. Solid-state photoluminescence measurements demonstrated quantum yields of 27.94% (ZnL), 0.90% ([ZnL]₂Eu), 1.82% ([ZnL]₂Tb), 1.05% ([ZnL]₂Gd), 0.65% (β-[ZnL]Eu), 1.16% (β-[ZnL]Tb), and 0.70% (β-[ZnL]Gd), indicating their potential as advanced fluorescent rare-earth materials. The LED devices based on complexes β-[ZnL]Eu and β-[ZnL]Tb exhibit stronger emission intensities compared to those based on complexes [ZnL]₂Eu and [ZnL]₂Tb. The obtained complexes were fabricated in LED; the CIE chromaticity coordinates of complexes β-[ZnL]Eu and β-[ZnL]Tb are (0.344, 0.316) and (0.347, 0.323), respectively, which are very close to the standard white light coordinates (0.33, 0.33).</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesis of Thiazinoquinolines and Evaluation of Antimicrobial and Antioxidant Activity Employing ZnO/CuO@GO Organometallic Nanocatalyst","authors":"Fatemeh Sheikholeslami-Farahani,&nbsp;Azadeh Parhami,&nbsp;Khatereh Khandan Barani,&nbsp;Somayeh Akbari","doi":"10.1002/aoc.70302","DOIUrl":"https://doi.org/10.1002/aoc.70302","url":null,"abstract":"<div>\u0000 \u0000 <p>This study effectively synthesized thiazinoquinolines, a new type of fused heterocyclic compounds, using a multicomponent process with high efficiency. The procedure employed naphthylamine, 2-arylidenemalononitrile, and isothiocyanates in an aqueous solution at ambient temperature, utilizing ZnO/CuO@GO as a recyclable catalyst. Because of having an NH group in the synthesized compounds, we investigate the antioxidant property of some synthesized thiazinoquinoline by diphenyl-picrylhydrazine (DPPH) radical trapping and the power of the ferric reduction experiment. Also, employing Gram-positive and Gram-negative bacteria in the disk diffusion procedure confirmed the antimicrobial effect of some thiazinoquinoline derivatives. The results showed that synthesized compounds prevented bacterial growth. The synthesis of fused thiazinoquinolines demonstrated several advantageous properties, including rapid reactions, elevated yields of the final product, and straightforward separation of the catalyst and product from the reaction mixture.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bis-1,2,3-Triazole Incorporated Organosilatrane for Dual Recognition of Cystine and Zr (IV): Exploring the Antioxidant Activity and Docking Study","authors":"Gurjaspreet Singh,&nbsp;Jigmat Stanzin,&nbsp;Jashan Deep Kaur,&nbsp;Pooja Malik,&nbsp;Harshbir Kaur,&nbsp;Anu Radha,&nbsp; Komal,&nbsp;Vinit Yadav,&nbsp; Vikas","doi":"10.1002/aoc.70371","DOIUrl":"https://doi.org/10.1002/aoc.70371","url":null,"abstract":"<div>\u0000 \u0000 <p>A new bis-1,2,3-triazole associated silatrane 5 was synthesized and characterized by various analytical spectroscopic techniques such as FT-IR, ¹H &amp;¹³C-NMR spectroscopy, and mass spectrometry. The probe <b>5</b> was employed for selective detection of cystine (Cys2) and Zr (IV) ion under spectrophotometric analysis. The LOD value for Cys2 was found to be 6.66 × 10⁻⁶ M under UV–visible spectrophotometry and for Zr (IV) was 4.82 × 10⁻⁷ M under fluorescence study. The stoichiometric ratio was found to be 1:1 for Cys2 and Zr (IV). The probe <b>5</b> has effectively scavenged DPPH, indicating that it possesses antioxidant properties. Using molecular docking, the binding energy against cystathionine protein was observed to be −6.24 kcal/mol. The above findings indicate that the probe <b>5</b> has potential applications in sensing as well as in biological fields.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitive Detection and Visual Recognition of Emodin Based on a Zn Coordination Polymer Probe","authors":"Ruijie Xu,&nbsp;Yefang Yang,&nbsp;Shaowen Qie,&nbsp;Wenping Hu,&nbsp;Wenting Li,&nbsp;Ming Hu","doi":"10.1002/aoc.70377","DOIUrl":"https://doi.org/10.1002/aoc.70377","url":null,"abstract":"<div>\u0000 \u0000 <p>Based on 2,4,6-pyridinetricarboxylic acid (H₃ptba) and <i>o</i>-phenanthroline (phen), a zinc-based fluorescence coordination polymer was successfully synthesized, namely, [Zn₃(ptba)₂(phen)₂(H₂O)₄]_n (<b>1</b>). The single-crystal diffraction analysis shows that Zn²⁺ ions in complex <b>1</b> are alternately connected with ptba³⁻ and phen ligands to form a one-dimensional chain structure, which further constitutes a three-dimensional supramolecular architecture through the π···π interactions. Complex <b>1</b> demonstrated excellent stability of thermogravimetry and displayed good fluorescence intensity in aqueous solution with a wide pH range. In this work, complex <b>1</b> was used as a fluorescence sensor for the detection of the emodin (Emo) molecule. It was found that complex <b>1</b> had high sensitivity with the detection limit of 1.0 × 10⁻⁷ M and simultaneously displayed specific selectivity for the exploration of the Emo molecule. The dynamic quenching, the absorption competition, and the photo-induced electron transfer process are responsible for the recognition mechanism of complex <b>1</b> with sensing Emo. It is worth mentioning that a fluorescent film based on complex <b>1</b> was successfully fabricated, which could rapidly recognize the Emo molecule with the naked eye further.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrections to “Bimetallic Metal–Organic Framework (MOF)–Derived NiO/CuO-Embedded Carbon for Supercapacitor”","authors":"Hani Nasser Abdelhamid","doi":"10.1002/aoc.70362","DOIUrl":"https://doi.org/10.1002/aoc.70362","url":null,"abstract":"<p>\u0000 https://doi.org/10.1002/aoc.70193\u0000 </p><p>A typo was detected in the Funding statement.</p><p>We regret this typographical error.</p><p>The revised funding is outlined below.</p><p><b>Funding:</b> This work was supported and funded by the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University (IMSIU) (grant number IMSIU-DDRSP2503).</p>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/aoc.70362","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rational Design of AIPE-Active Cationic Ir(III) Complexes for Detecting Picric Acid in Aqueous Media","authors":"Qinglong Zhang,&nbsp;Ping He,&nbsp;Xinnan Wang,&nbsp;Chen Wang,&nbsp;Chao Yang,&nbsp;Chun Liu","doi":"10.1002/aoc.70370","DOIUrl":"https://doi.org/10.1002/aoc.70370","url":null,"abstract":"<div>\u0000 \u0000 <p>The efficient detection of nitroaromatic explosives is of great importance to social safety. For this purpose, three cationic Ir(III) complexes <b>Ir1</b>–<b>Ir3</b> were synthesized. <b>Ir1</b>–<b>Ir3</b> exhibit aggregation-induced phosphorescent emission (AIPE) properties and can be utilized for sensitively and selectively detecting picric acid (PA) in an H₂O/CH₃CN system. The results demonstrate that there is a positive correlation between the AIPE activities of Ir(III) complexes and their efficiencies in detecting PA. 4-Fluorophenyl-substituted complex <b>Ir3</b> possesses the highest AIPE activity and exhibits the highest quenching constant (<i>K</i>_SV = 635,621 M⁻¹) and the lowest limit of detection (LOD = 2.6 nM) for detecting PA among these complexes. The crystal structures reveal that the higher AIPE activity of <b>Ir3</b> is owing to its more abundant molecular interactions compared to <b>Ir2</b>. The density functional theory calculations suggest that luminescence quenching is due to the photo-induced electron transfer.</p>\u0000 </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 9","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}