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Annual review of chemical and biomolecular engineering最新文献

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Life and Times in Engineering and Chemical Engineering. 工程与化学工程中的生命与时代。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 DOI: 10.1146/annurev-chembioeng-011420-125935
J F Davidson
{"title":"Life and Times in Engineering and Chemical Engineering.","authors":"J F Davidson","doi":"10.1146/annurev-chembioeng-011420-125935","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-011420-125935","url":null,"abstract":"<p><p>John Davidson was widely recognized as the founding father of fluidization in chemical engineering. He was a great thinker and had a tremendous ability to distill complicated problems into much simpler concepts. Much of his thinking was set out, along with that of his coauthor David Harrison, in their book <i>Fluidised Particles</i>, first published in 1963, a book that is still used today. John was still coming into his office in Cambridge until the very last weeks of his life, where he continued to work with final-year undergraduates and graduate students. Fluidization, and two-phase flows, continued to fascinate him, and that enthusiasm was transmitted to those around him. The following article was the last work that he wrote and was very much a reflection on his life and career. John passed away on Christmas Day 2019, with the article in its final stages of preparation.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"23-34"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-chembioeng-011420-125935","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38022923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Biological Assembly of Modular Protein Building Blocks as Sensing, Delivery, and Therapeutic Agents. 模块化蛋白质构建块作为传感、传递和治疗剂的生物组装。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 Epub Date: 2020-03-10 DOI: 10.1146/annurev-chembioeng-101519-121526
Emily A Berckman, Emily J Hartzell, Alexander A Mitkas, Qing Sun, Wilfred Chen
{"title":"Biological Assembly of Modular Protein Building Blocks as Sensing, Delivery, and Therapeutic Agents.","authors":"Emily A Berckman,&nbsp;Emily J Hartzell,&nbsp;Alexander A Mitkas,&nbsp;Qing Sun,&nbsp;Wilfred Chen","doi":"10.1146/annurev-chembioeng-101519-121526","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-101519-121526","url":null,"abstract":"<p><p>Nature has evolved a wide range of strategies to create self-assembled protein nanostructures with structurally defined architectures that serve a myriad of highly specialized biological functions. With the advent of biological tools for site-specific protein modifications and de novo protein design, a wide range of customized protein nanocarriers have been created using both natural and synthetic biological building blocks to mimic these native designs for targeted biomedical applications. In this review, different design frameworks and synthetic decoration strategies for achieving these functional protein nanostructures are summarized. Key attributes of these designer protein nanostructures, their unique functions, and their impact on biosensing and therapeutic applications are discussed.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"35-62"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-chembioeng-101519-121526","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37724152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Separation Processes to Provide Pure Enantiomers and Plant Ingredients. 提供纯对映体和植物成分的分离工艺。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 Epub Date: 2020-03-20 DOI: 10.1146/annurev-chembioeng-100419-103732
Heike Lorenz, Andreas Seidel-Morgenstern
{"title":"Separation Processes to Provide Pure Enantiomers and Plant Ingredients.","authors":"Heike Lorenz,&nbsp;Andreas Seidel-Morgenstern","doi":"10.1146/annurev-chembioeng-100419-103732","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100419-103732","url":null,"abstract":"<p><p>Enantiomer separation and the isolation of natural products from plants pose challenging separation problems resulting from the similarity of molecules and the number of compounds present in synthesis or extract mixtures. Furthermore, limited theory is available to predict productivities for possible alternative separation techniques. The application and performance of chromatography- and crystallization-based processes are demonstrated for various case studies devoted to isolating valuable target compounds from complex initial mixtures. In all cases, the first emphasis is set to determine the process-specific phase equilibria to identify feasible process options. For all examples considered, yields and productivities are evaluated and compared for different scenarios. Guidelines to approach and solve similar separation tasks are given.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"469-502"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-chembioeng-100419-103732","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37759179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Cellular Automata in Chemistry and Chemical Engineering. 化学与化学工程中的元胞自动机。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 DOI: 10.1146/annurev-chembioeng-093019-075250
Natalia V Menshutina, Andrey V Kolnoochenko, Evgeniy A Lebedev
{"title":"Cellular Automata in Chemistry and Chemical Engineering.","authors":"Natalia V Menshutina,&nbsp;Andrey V Kolnoochenko,&nbsp;Evgeniy A Lebedev","doi":"10.1146/annurev-chembioeng-093019-075250","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-093019-075250","url":null,"abstract":"<p><p>We review the modern state of cellular automata (CA) applications for solving practical problems in chemistry and chemical technology. We consider the problems of material structure modeling and prediction of materials' morphology-dependent properties. We review the use of the CA approach for modeling diffusion, crystallization, dissolution, erosion, corrosion, adsorption, and hydration processes. We also consider examples of hybrid CA-based models, which are combinations of various CA with other computational approaches and modeling methods. Finally, we discuss the use of high-performance parallel computing to increase the efficiency of CA.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"87-108"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-chembioeng-093019-075250","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38022921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Molecular Modeling and Simulations of Peptide-Polymer Conjugates. 肽-聚合物共轭物的分子建模与模拟。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 DOI: 10.1146/annurev-chembioeng-092319-083243
Phillip A Taylor, Arthi Jayaraman
{"title":"Molecular Modeling and Simulations of Peptide-Polymer Conjugates.","authors":"Phillip A Taylor,&nbsp;Arthi Jayaraman","doi":"10.1146/annurev-chembioeng-092319-083243","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-092319-083243","url":null,"abstract":"<p><p>Peptide-polymer conjugates are a class of soft materials composed of covalently linked blocks of protein/polypeptides and synthetic/natural polymers. These materials are practically useful in biological applications, such as drug delivery, DNA/gene delivery, and antimicrobial coatings, as well as nonbiological applications, such as electronics, separations, optics, and sensing. Given their broad applicability, there is motivation to understand the molecular and macroscale structure, dynamics, and thermodynamic behavior exhibited by such materials. We focus on the past and ongoing molecular simulation studies aimed at obtaining such fundamental understanding and predicting molecular design rules for the target function. We describe briefly the experimental work in this field that validates or motivates these computational studies. We also describe the various models (e.g., atomistic, coarse-grained, or hybrid) and simulation methods (e.g., stochastic versus deterministic, enhanced sampling) that have been used and the types of questions that have been answered using these computational approaches.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"257-276"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-chembioeng-092319-083243","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38022922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Introduction. 介绍。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 DOI: 10.1146/annurev-ch-11-042120-100001
Michael Doherty, Rachel Segalman
{"title":"Introduction.","authors":"Michael Doherty,&nbsp;Rachel Segalman","doi":"10.1146/annurev-ch-11-042120-100001","DOIUrl":"https://doi.org/10.1146/annurev-ch-11-042120-100001","url":null,"abstract":"","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"i-ii"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-ch-11-042120-100001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38022924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bioprivileged Molecules: Integrating Biological and Chemical Catalysis for Biomass Conversion. 生物特权分子:整合生物质转化的生物和化学催化。
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-06-07 Epub Date: 2020-03-10 DOI: 10.1146/annurev-chembioeng-101519-121127
Jiajie Huo, Brent H Shanks
{"title":"Bioprivileged Molecules: Integrating Biological and Chemical Catalysis for Biomass Conversion.","authors":"Jiajie Huo,&nbsp;Brent H Shanks","doi":"10.1146/annurev-chembioeng-101519-121127","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-101519-121127","url":null,"abstract":"<p><p>Further development of biomass conversions to viable chemicals and fuels will require improved atom utilization, process efficiency, and synergistic allocation of carbon feedstock into diverse products, as is the case in the well-developed petroleum industry. The integration of biological and chemical processes, which harnesses the strength of each type of process, can lead to advantaged processes over processes limited to one or the other. This synergy can be achieved through bioprivileged molecules that can be leveraged to produce a diversity of products, including both replacement molecules and novel molecules with enhanced performance properties. However, important challenges arise in the development of bioprivileged molecules. This review discusses the integration of biological and chemical processes and its use in the development of bioprivileged molecules, with a further focus on key hurdles that must be overcome for successful implementation.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"11 ","pages":"63-85"},"PeriodicalIF":8.4,"publicationDate":"2020-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-chembioeng-101519-121127","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37722707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Development and Validation of an New High Performance Liquid Chromatography Method for Determination of Apixaban Isomers 高效液相色谱法测定阿哌沙班异构体的建立与验证
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2020-01-04 DOI: 10.11648/J.CBE.20200501.11
A. Gosar, R. Phadke, Deepesh Patil, K. Gupta, P. Thakur
{"title":"Development and Validation of an New High Performance Liquid Chromatography Method for Determination of Apixaban Isomers","authors":"A. Gosar, R. Phadke, Deepesh Patil, K. Gupta, P. Thakur","doi":"10.11648/J.CBE.20200501.11","DOIUrl":"https://doi.org/10.11648/J.CBE.20200501.11","url":null,"abstract":"The purpose of this research study is to develop a novel, simple, precise, accurate and economical method for determination of Apixaban API isomers. Apixaban API has three isomer as ortho, meta and para. In reverse phase and normal phase chromatography it was very difficult to separate these isomer; hence new chiral technique was adopted. This chromatographic method was developed on chiralpak IA column (250×4.6×5µm) with isocritic technique. The detection of isomeric impurities were observed at wavelength 290nm. This analytical method was validated as per ICH guideline and regression analysis showed R value (correlation coefficient) > 0.999 for Apixaban API and its isomeric impurities. A solution of Apixaban in dichloromethane was found stable up to 48 hrs. The degradation study was done within the given guidelines prescribed by ICH. The method is validated for Linearity, Accuracy and Precision.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"7 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2020-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81028646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Concise Review on the Significance of QSAR in Drug Design 简要综述QSAR在药物设计中的意义
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2019-12-27 DOI: 10.11648/J.CBE.20190404.11
H. Tandon, T. Chakraborty, V. Suhag
{"title":"A Concise Review on the Significance of QSAR in Drug Design","authors":"H. Tandon, T. Chakraborty, V. Suhag","doi":"10.11648/J.CBE.20190404.11","DOIUrl":"https://doi.org/10.11648/J.CBE.20190404.11","url":null,"abstract":"Drug designing is a crucial step in the exploration of novel drugs which requires potent methodologies. One of such methodologies is Quantitative Structure Activity Relationship (QSAR) which is a widely used statistical tool that correlates the structure of a molecule to a biological activity as a function of molecular descriptors, thereby, playing an essential role in the drug designing. QSAR utilizes Density Functional Theory (DFT) based chemical descriptors for this purpose. The selection of such significant molecular descriptors from various available descriptors is the foremost challenge in a QSAR as structural descriptors are representative of the molecular characteristics accountable for the relevant activity. Recently, new QSAR approaches have been introduced which further enhance the study of the activities. Further, the constructed QSAR models also need to be tested and validated for their efficiency and practical usage. As the QSAR models are structure specific, they may not be universally applicable. However, because of their high precision and efficacy, they have a promising future in the world of drug design. This review briefly summarizes the role of descriptor based QSAR in drug design in conjunction with existing QSAR approaches and also the utility as well as constraints of this approach in drug design.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"7 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87804046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Food Traceability System: Current State and Future Needs of the Nigerian Poultry and Poultry Product Supply Chain 食品可追溯系统:尼日利亚家禽和家禽产品供应链的现状和未来需求
IF 8.4 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2019-12-25 DOI: 10.11648/j.cbe.20190403.11
H. K. Bako, M. Dandago, S. Nassarawa
{"title":"Food Traceability System: Current State and Future Needs of the Nigerian Poultry and Poultry Product Supply Chain","authors":"H. K. Bako, M. Dandago, S. Nassarawa","doi":"10.11648/j.cbe.20190403.11","DOIUrl":"https://doi.org/10.11648/j.cbe.20190403.11","url":null,"abstract":"The study revealed a thriving Nigerian food industry and policymakers toward understanding food traceability systems in three ways. Firstly, a realistic strategy toward supply chain visibility. Secondly, verify the concept relating to the implementation of documentation and technological innovations. Thirdly, emphasized the significance of food safety and food recall taking into account current status and future needs and how a traceability system would be realized in the poultry sector by giving a clear roadmap for technology. Also the work explained the current state of the two most practiced method of poultry production; backyard and commercial scale was also investigated.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"52 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73579361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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