Emerging Biomedical Applications Based on the Response of Magnetic Nanoparticles to Time-Varying Magnetic Fields.

IF 4.4 2区 化学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY
Angelie Rivera-Rodriguez, Carlos M Rinaldi-Ramos
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引用次数: 13

Abstract

Magnetic nanoparticles are of interest for biomedical applications because of their biocompatibility, tunable surface chemistry, and actuation using applied magnetic fields. Magnetic nanoparticles respond to time-varying magnetic fields via physical particle rotation or internal dipole reorientation, which can result in signal generation or conversion of magnetic energy to heat. This dynamic magnetization response enables their use as tracers in magnetic particle imaging (MPI), an emerging biomedical imaging modality in which signal is quantitative of tracer mass and there is no tissue background signal or signal attenuation. Conversion of magnetic energy to heat motivates use in nanoscale thermal cancer therapy, magnetic actuation of drug release, and rapid rewarming of cryopreserved organs. This review introduces basic concepts of magnetic nanoparticle response to time-varying magnetic fields and presents recent advances in the field, with an emphasis on MPI and conversion of magnetic energy to heat.

基于磁性纳米颗粒对时变磁场响应的新兴生物医学应用。
磁性纳米颗粒因其生物相容性、可调节的表面化学性质和利用外加磁场驱动而被应用于生物医学领域。磁性纳米粒子通过物理粒子旋转或内部偶极子重定向对时变磁场做出响应,从而产生信号或将磁能转化为热能。这种动态磁化响应使其成为磁颗粒成像(MPI)中的示踪剂,MPI是一种新兴的生物医学成像方式,其中信号是示踪剂质量的定量,没有组织背景信号或信号衰减。将磁能转化为热能,可用于纳米级热癌治疗、磁驱动药物释放和冷冻保存器官的快速再加热。本文介绍了磁性纳米粒子对时变磁场响应的基本概念,并介绍了该领域的最新进展,重点介绍了MPI和磁能到热的转换。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
6.00%
发文量
810
期刊介绍: ACS Applied Polymer Materials is an interdisciplinary journal publishing original research covering all aspects of engineering, chemistry, physics, and biology relevant to applications of polymers. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates fundamental knowledge in the areas of materials, engineering, physics, bioscience, polymer science and chemistry into important polymer applications. The journal is specifically interested in work that addresses relationships among structure, processing, morphology, chemistry, properties, and function as well as work that provide insights into mechanisms critical to the performance of the polymer for applications.
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