Chinock Cheong, Na Won Kim, Hye Sun Lee, Jeonghyun Kang
{"title":"Intracorporeal versus extracorporeal anastomosis in minimally invasive right hemicolectomy: systematic review and meta-analysis of randomized controlled trials.","authors":"Chinock Cheong, Na Won Kim, Hye Sun Lee, Jeonghyun Kang","doi":"10.4174/astr.2024.106.1.1","DOIUrl":"10.4174/astr.2024.106.1.1","url":null,"abstract":"<p><strong>Purpose: </strong>Compared with extracorporeal anastomosis (ECA), intracorporeal anastomosis (ICA) is expected to provide some benefits, including a shorter operation time and less intraoperative bleeding. Nevertheless, the benefits of ICA have mainly been evaluated in nonrandomized studies. Owing to the recent update of randomized controlled trials (RCTs) for minimally invasive surgery (MIS) of right hemicolectomy (RHC), the need to measure the actual effect by synthesizing the outcomes of these studies has emerged.</p><p><strong>Methods: </strong>We performed a comprehensive search of the PubMed, Embase, and Cochrane databases (from inception to January 30, 2023) for studies that applied ICA and ECA for RHC with MIS. We included 7 RCTs. The operation time, intraoperative blood loss, conversion rate, length of incision, and postoperative outcomes such as ileus, anastomosis leakage, length of hospitalization, and postoperative pain were compared between ICA and ECA.</p><p><strong>Results: </strong>A total of 740 patients were included in the study. Among them, 377 and 373 underwent ICA and ECA, respectively. There were significant differences in age (P = 0.003) and incision type (P < 0.001) between ICA and ECA. ICA was associated with a significantly longer operation time (P = 0.033). Although the postoperative pain associated with ICA was significantly lower than that associated with ECA on postoperative day 2 (POD 2) (P = 0.003), it was not different on POD 3 between the groups. Other perioperative outcomes were similar between the 2 groups.</p><p><strong>Conclusion: </strong>In this meta-analysis, ICA did not significantly improve short-term outcomes compared to ECA; other advantages to overcome ICA's longer operation time are not clear.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radical resection benefits patients suffering pancreatic ductal adenocarcinoma with liver oligometastases.","authors":"Qingyan Kong, Fei Teng, Hang Li, Zheyu Chen","doi":"10.4174/astr.2024.106.1.51","DOIUrl":"10.4174/astr.2024.106.1.51","url":null,"abstract":"<p><strong>Purpose: </strong>Whether patients suffering liver oligometastases from pancreatic ductal adenocarcinoma (LOPDA) should undergo surgical treatment remains controversial.</p><p><strong>Methods: </strong>PubMed and Embase databases were systematically reviewed until 2023 June. Survival data were collected from the Kaplan-Meier curves. Safety and survival were evaluated using primary outcomes such as 1-year, 3-year, and 5-year survival rates, and 30-day mortality and morbidity. A subgroup meta-analysis was conducted to compare survival rates post-synchronous resection and resection post-neoadjuvant chemotherapy in LOPDA.</p><p><strong>Results: </strong>Our analysis of 15 studies involving 1,818 patients (surgical group, 648 and nonsurgical group, 1,170) indicates that radical hepatectomy for LOPDA notably improved 1-year (odds ratio [OR], 3.24; 95% confidence interval [CI], 2.45-4.28; P < 0.001), 3-year (OR, 5.74; 95% CI, 3.36-8.90; P < 0.001), and 5-year (OR, 4.89; 95% CI, 2.56-9.35; P < 0.001) overall survival (OS) rates. A separate analysis of 6 studies with 750 patients demonstrated the safety of LOPDA surgery, with no increase in postoperative complications (P = 0.26 for overall morbidity and P = 0.99 for mortality) compared to the patients with no metastatic disease from the pancreatic ductal adenocarcinoma (NMPDA) group. The NMPDA group showed superior 1-year and 3-year OS rates, but not 5-year OS rates compared to the LOPDA group.</p><p><strong>Conclusion: </strong>Surgical treatment apparently offers a survival advantage to LOPDA by comparing with nonsurgical groups in 1-, 3-, and 5-year OS rates. Radical resection for LOPDA is a safe treatment without more postoperative complications than NMPDA.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mirang Lee, Youngmin Han, Jae Seung Kang, Yoo Jin Choi, Hee Ju Sohn, Wooil Kwon, Jin-Young Jang
{"title":"Training efficacy of robotic duct-to-mucosa pancreaticojejunostomy simulation using silicone models for surgical fellows.","authors":"Mirang Lee, Youngmin Han, Jae Seung Kang, Yoo Jin Choi, Hee Ju Sohn, Wooil Kwon, Jin-Young Jang","doi":"10.4174/astr.2024.106.1.45","DOIUrl":"10.4174/astr.2024.106.1.45","url":null,"abstract":"<p><strong>Purpose: </strong>In the era of minimally invasive surgery (MIS), robotic pancreatoduodenectomy (PD) is actively performed, and clinical fellows need to thoroughly prepare for MIS-PD during the training process. Although pancreaticojejunostomy (PJ) is a difficult anastomosis that requires repeated practice, there are obstacles preventing its practice that concerns patient safety and limited time in the actual operating room. This study evaluated the efficacy of simulation-based training of robotic duct-to-mucosa PJ using pancreatic and intestinal silicone models using a scoring system.</p><p><strong>Methods: </strong>Three pancreatobiliary clinical fellows who had never performed a real robotic PJ participated in this study. Each trainee, who was well acquainted with master's video created by a senor surgeon, performed the robotic PJ procedures 9 times, and 3 independent pancreatobiliary surgeons assessed the videos and analyzed the scores using a blind method.</p><p><strong>Results: </strong>The mean robotic PJ times for the 3 trainees were 42.8 and 29.1 minutes for the first and 9th videos, respectively. The mean score was 13.8 (range, 6-17) for the first video and 17.7 (range, 15-19) for the 9th video. When comparing earlier and later attempts, the PJ time decreased significantly (2,201.67 seconds <i>vs.</i> 2,045.50 seconds, P = 0.007), whereas test scores increased significantly (total score 14.22 <i>vs.</i> 16.89, P = 0.011).</p><p><strong>Conclusion: </strong>This robotic education system will help pancreatobiliary trainees overcome the learning curves efficiently and quickly without raising ethical concerns associated with animal models or direct practice with human subjects. This will be of practical assistance to trainees preparing for MIS-PD.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xi Bu, Jian-Xun Ma, You-Chen Xia, Bi Li, Yue Lang, Shi-Lu Yin
{"title":"Application of magnetic resonance imaging with intraoperative color Doppler ultrasound in the treatment of patients with polyacrylamide hydrogel injected for breast augmentation: a retrospective study of 204 cases for 12 years.","authors":"Xi Bu, Jian-Xun Ma, You-Chen Xia, Bi Li, Yue Lang, Shi-Lu Yin","doi":"10.4174/astr.2024.106.1.31","DOIUrl":"10.4174/astr.2024.106.1.31","url":null,"abstract":"<p><strong>Purpose: </strong>Polyacrylamide hydrogel (PAHG), which had been used widely for breast augmentation, has been banned for more than 15 years. Patients who had been injected PAHG for breast augmentation need evacuation surgery to remove as much as possible. To provide a series of diagnosis and treatment process MRI and intraoperative color Doppler ultrasound are combined for maximal removal of PAHG.</p><p><strong>Methods: </strong>The patients who received evacuation surgery in Peking University Third Hospital from 2010 to 2022 after PAHG injection for breast augmentation were included in this research. MR scanning was performed preoperatively and postoperatively in some of these patients and color Doppler ultrasound was applied to help evacuate PAHG intraoperatively. The mean clearance rate of PAHG was calculated according to the MRI outcomes.</p><p><strong>Results: </strong>Two hundred and 4 patients had received evacuation surgery after PAHG injection for breast augmentation with an average age of 42.8 years and an average body mass index of 21.2 kg/m<sup>2</sup>. The average PAHG retention time was 13.5 years. Among them, 52 patients underwent pre- and postoperative MRI scanning. The mean three-dimensional (3D) volume of PAHG was 684.8 mL (range, 350.0-1,123.9 mL), and the average residual 3D volume of PAHG was 53.7 mL (range, 12.4-98.3 mL). The mean clearance rate was 92.1%.</p><p><strong>Conclusion: </strong>MRI and intraoperative color Doppler ultrasound can provide effective and precise location information of PAHG for evacuation surgery, which is a reliable method to ensure the maximal removal of PAHG.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ja Kyung Lee, Eu Jeong Ku, Su-Jin Kim, Woochul Kim, Jae Won Cho, Kyong Yeun Jung, Hyeong Won Yu, Yea Eun Kang, Mijin Kim, Hee Kyung Kim, Junsun Ryu, June Young Choi
{"title":"Effect of thyroid-stimulating hormone suppression on quality of life in thyroid lobectomy patients: interim analysis of a multicenter, randomized controlled trial in low- to intermediate-risk thyroid cancer patients (MASTER study).","authors":"Ja Kyung Lee, Eu Jeong Ku, Su-Jin Kim, Woochul Kim, Jae Won Cho, Kyong Yeun Jung, Hyeong Won Yu, Yea Eun Kang, Mijin Kim, Hee Kyung Kim, Junsun Ryu, June Young Choi","doi":"10.4174/astr.2024.106.1.19","DOIUrl":"10.4174/astr.2024.106.1.19","url":null,"abstract":"<p><strong>Purpose: </strong>Current clinical practices favor less or no thyroid-stimulating hormone (TSH) suppression for low- to intermediate-risk thyroid cancer patients who receive thyroid lobectomy. The association of TSH suppression on health-related quality of life (HR-QoL) in patients after thyroid lobectomy is not well studied. This study aimed to evaluate the effect of TSH suppression on patient HR-QoL after thyroid lobectomy.</p><p><strong>Methods: </strong>This study included patients enrolled in an ongoing, multicenter, randomized controlled study investigating the effects of TSH suppression. Patients were randomized to either the low-TSH group (TSH target range, 0.3-1.99 µIU/mL) or the high-TSH group (TSH target range, 2.0-7.99 µIU/mL). The HR-QoL, hyperthyroidism symptom, and depression symptom questionnaires performed preoperatively and 2 weeks and 3 months postoperatively were evaluated.</p><p><strong>Results: </strong>Total of 669 patients (low-TSH group, 340; high-TSH group, 329) were included. Although total HR-QoL score changes were not different between the 2 groups, the high-TSH group had a significantly higher score in the physical domain at postoperative 3 months (P = 0.046). The 2 groups did not have significant differences in hyperthyroidism and depression scores.</p><p><strong>Conclusion: </strong>In the short-term postoperative period, the physical HR-QoL scores in thyroid lobectomy patients were better when they did not receive TSH suppression. This study suggests the importance of considering HR-QoL when setting TSH suppression targets in thyroid lobectomy patients.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Byung-Chang Kim, Shin Jeong Pak, Douk Kwon, Jae Won Cho, Won Woong Kim, Yu-Mi Lee, Kye Jin Park, Ki-Wook Chung, Tae-Yon Sung
{"title":"Silent pheochromocytoma in adrenal incidentaloma: unveiling clinical and radiological characteristics.","authors":"Byung-Chang Kim, Shin Jeong Pak, Douk Kwon, Jae Won Cho, Won Woong Kim, Yu-Mi Lee, Kye Jin Park, Ki-Wook Chung, Tae-Yon Sung","doi":"10.4174/astr.2024.106.1.38","DOIUrl":"10.4174/astr.2024.106.1.38","url":null,"abstract":"<p><strong>Purpose: </strong>Silent pheochromocytoma refers to tumors without signs and symptoms of catecholamine excess. This study aimed to clarify the clinical, radiological characteristics, and perioperative features of silent pheochromocytomas diagnosed after adrenalectomy for adrenal incidentaloma.</p><p><strong>Methods: </strong>Medical records of patients who underwent adrenalectomy for adrenal incidentaloma and were subsequently diagnosed with silent pheochromocytoma between January 2000 and December 2020 were retrospectively reviewed for demographic, diagnostic, surgical, and pathological findings.</p><p><strong>Results: </strong>Of the 130 patients who underwent adrenalectomy for incidentaloma, 8 (6.1%) were diagnosed with silent pheochromocytoma. Almost all patients had no hypertensive symptoms and their baseline hormonal levels remained within normal ranges. All patients exhibited tumor size >4 cm, precontrast Hounsfield unit >10, and absolute washout <60%. Intraoperative hypertensive events were noted in 2 patients (25.0%) in whom antiadrenergic medications were not administered. All patients in the intraoperative hypertensive event group exhibited atypical features on CT, whereas 83.3% of patients in the non-intraoperative hypertensive event group showed atypical features on CT imaging.</p><p><strong>Conclusion: </strong>Silent pheochromocytomas share radiological traits with malignant adrenal tumors. Suspicious features on CT scans warrant surgical consideration for appropriate treatment. Administering alpha-blockers can enhance hemodynamic stability during adrenalectomy in suspected silent pheochromocytoma cases.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RETRACTION: Retraction of the Original Articles.","authors":"","doi":"10.4174/astr.2024.106.1.61","DOIUrl":"https://doi.org/10.4174/astr.2024.106.1.61","url":null,"abstract":"<p><p>[This retracts the article on p. 404 in vol. 66.][This retracts the article on p. 458 in vol. 67.][This retracts the article on p. 375 in vol. 70.].</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139416234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"National cancer screening program for colorectal cancer in Korea.","authors":"Seung Min Baik, Ryung-Ah Lee","doi":"10.4174/astr.2023.105.6.333","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.333","url":null,"abstract":"Colorectal cancer is the 3rd leading cause of cancer-related deaths in Korea, ranking 4th and 3rd among men and women, respectively. It is also the most common cause of cancer-related deaths in women older than 64 years. This study assessed the National Cancer Screening Program for colorectal cancer and examined its efficacy in enhancing public health. The fecal occult blood test (FOBT), a traditional noninvasive colorectal cancer screening test that can be performed on an outpatient basis was replaced with the fecal immunochemical test (FIT) because of the latter's better predictive value. Since 2004, the Government of South Korea has recommended an annual FIT for people aged 50 years and older as the first step in colorectal cancer screening. Individuals who test positive on the FIT are scheduled for follow-up screening procedures, such as colonoscopy or double-contrast barium enema, whereas those who have a negative FOBT are not recommended for colonoscopy. Colonoscopy, as a screening tool in Korea, has definite merits because it is highly accessible to patients and is performed by qualified specialists. Although the domestic colorectal cancer screening rate is relatively stable, there is scope for improvement. Owing to the low cost of colonoscopy and the wealth of skilled endoscopy specialists, the number of intention-to-screen procedures for colonoscopy has increased. As Korea is rapidly becoming an ultra-elderly society, it is time to reconsider the revision of the classical screening program and recommend region-specific, cost-effective guidelines.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin-Kwon Lee, Seung-Jun Lee, Young-Sool Hah, Yeong-Ho Ji, Young-Tae Ju, Young-Joon Lee, Chi-Young Jeong, Ju-Yeon Kim, Ji-Ho Park, Jae-Myung Kim, Jin-Kyu Cho, Han-Gil Kim, Seung-Jin Kwag
{"title":"Exploring the role of copine 1 in human colorectal cancer: investigating its association with tumorigenesis and metastasis.","authors":"Jin-Kwon Lee, Seung-Jun Lee, Young-Sool Hah, Yeong-Ho Ji, Young-Tae Ju, Young-Joon Lee, Chi-Young Jeong, Ju-Yeon Kim, Ji-Ho Park, Jae-Myung Kim, Jin-Kyu Cho, Han-Gil Kim, Seung-Jin Kwag","doi":"10.4174/astr.2023.105.6.385","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.385","url":null,"abstract":"This study aimed to investigate the potential role of copine-1 (CPNE1), a calcium-dependent membrane-binding protein encoded by the <i>CPNE1</i> gene, in colorectal cancer (CRC). Despite previous research on the involvement of copine family members in various solid tumors, the specific role of CPNE1 in CRC remains poorly understood.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138688504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protective strategy for the caudate lobe bile duct during left hemihepatectomy based on imaging data analysis.","authors":"Zhengyi Wu, Liang Sun, Ke Ning, Zhendong Chen, Zhipeng Wu, Hanqing Yang, Jinlong Yan, Xiangbao Yin","doi":"10.4174/astr.2023.105.6.369","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.369","url":null,"abstract":"This study was performed to analyze the rule of confluence of the caudate lobe bile duct (CLD) into the left hepatic duct (LHD) and to discuss the protective strategy during left hemihepatectomy.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}