Young Joo Kim, Jong Hyuk Yun, Sung Hoon Hong, Jong Eun Lee, Sun Wook Han, Sung Yong Kim
{"title":"Is wide excision really needed? Correlation between resection margin and recurrence in benign phyllodes tumors of the breast.","authors":"Young Joo Kim, Jong Hyuk Yun, Sung Hoon Hong, Jong Eun Lee, Sun Wook Han, Sung Yong Kim","doi":"10.4174/astr.2023.105.6.353","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.353","url":null,"abstract":"Phyllodes tumors are similar to fibroadenomas in imaging and in pathological characteristics and are difficult to identify preoperatively. The purpose of this study was to analyze the recurrence rate after excision stratified by the surgical margin width and to propose and emphasize the \"wait and watch\" treatment strategy for benign phyllodes tumors.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sujin Gang, Hyunhee Kwon, Jueun Park, Dae Yeon Kim
{"title":"The outcome of hiatal hernia repair and factors associated with surgical outcome in the pediatric population: a single-center experience.","authors":"Sujin Gang, Hyunhee Kwon, Jueun Park, Dae Yeon Kim","doi":"10.4174/astr.2023.105.6.396","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.396","url":null,"abstract":"Hiatal hernia in children is a rare condition, and there is limited knowledge available about the disease itself. There is currently no agreement or consensus on the treatment of hiatal hernia in the pediatric population due to lack of evidence. In this study, we were to assess our experience with hiatal hernia, including the characteristics of our patients, surgical outcomes, and factors that influence the outcomes.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seunghui Lee, Miyeong Lee, Sangdon Kwan, Soohyung Kim, Ki Bum Park, Oh Kyoung Kwon, Ji Yeon Park
{"title":"Surgical outcomes and survival of patients over 80 years old who underwent curative resection for gastric cancer.","authors":"Seunghui Lee, Miyeong Lee, Sangdon Kwan, Soohyung Kim, Ki Bum Park, Oh Kyoung Kwon, Ji Yeon Park","doi":"10.4174/astr.2023.105.6.376","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.376","url":null,"abstract":"Among patients with gastric cancer who underwent radical gastrectomy, the proportion of patients aged ≥80 years has increased. This study aimed to evaluate surgical outcomes and survival of patients aged ≥80 years who underwent curative resection for gastric cancer and identify independent factors that affect postoperative survival.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seonju Kim, Yun Kyung Jung, Kyeong Geun Lee, Kyeong Sik Kim, Hanjun Kim, Dongho Choi, Sumi Lee, Boyoung Park
{"title":"A systematic review and meta-analysis of blood transfusion rates during liver resection by country.","authors":"Seonju Kim, Yun Kyung Jung, Kyeong Geun Lee, Kyeong Sik Kim, Hanjun Kim, Dongho Choi, Sumi Lee, Boyoung Park","doi":"10.4174/astr.2023.105.6.404","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.404","url":null,"abstract":"This study aimed to determine the blood transfusion rates during liver resection by country to prepare a basis for patient blood management policy.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kwang Hyun Yoon, Suk Jun Lee, Yujin Kim, Jee Hyun Ahn, Jee Ye Kim, Hyung Seok Park, Seung Il Kim, Seho Park
{"title":"A simplified risk scoring system for predicting high-risk groups in gene expression tests for patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative, and node-positive breast cancer.","authors":"Kwang Hyun Yoon, Suk Jun Lee, Yujin Kim, Jee Hyun Ahn, Jee Ye Kim, Hyung Seok Park, Seung Il Kim, Seho Park","doi":"10.4174/astr.2023.105.6.360","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.360","url":null,"abstract":"The gene expression test (GET) was used to predict the response to chemotherapy and the recurrence risk. Several randomized clinical trials have demonstrated that some patients with node-positive disease can achieve favorable survival outcomes even without adjuvant chemotherapy. This study aimed to predict the results of Oncotype DX (Genomic Health) and MammaPrint (Agendia) using traditional clinicopathological factors.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138688608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyung Uk Jung, Hyung Ook Kim, Hungdai Kim, Donghyoun Lee, Chinock Cheong
{"title":"Unveiling the profound advantages of total neoadjuvant therapy in rectal cancer: a trailblazing exploration.","authors":"Kyung Uk Jung, Hyung Ook Kim, Hungdai Kim, Donghyoun Lee, Chinock Cheong","doi":"10.4174/astr.2023.105.6.341","DOIUrl":"https://doi.org/10.4174/astr.2023.105.6.341","url":null,"abstract":"The standard treatments for locally advanced rectal cancer typically involved neoadjuvant therapy with either short-course radiation or long-course chemoradiation, followed by radical surgery and adjuvant chemotherapy. While the advancement of surgical techniques and the adoption of multimodal therapy have greatly contributed to reducing local failure, there has been limited improvement in overall survival, primarily due to the stagnation in systemic failure. In response to this challenge, a new strategy known as total neoadjuvant therapy (TNT) has emerged, involving the administration of both full-dose chemotherapy and radiation before surgery. It has shown promise in reducing systemic failure, enhancing tumor regression, and improving treatment adherence, ushering in a new era in the standard treatment of locally advanced rectal cancer. This review aims to summarize the evolution of multimodal treatments for locally advanced rectal cancer, ultimately converging into the current TNT strategy, and provides an assessment of the benefits and limitations of TNT based on available evidence, serving as a foundation for selecting the best treatment option.","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138681519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between preoperative modifiable lifestyle factors and mortality after cancer surgery: a population-based cohort study in South Korea.","authors":"Tak Kyu Oh, In-Ae Song","doi":"10.4174/astr.2023.105.4.179","DOIUrl":"https://doi.org/10.4174/astr.2023.105.4.179","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to examine whether preoperative lifestyle factors are associated with mortality after cancer surgery.</p><p><strong>Methods: </strong>This study used data from the National Health Insurance Service database in South Korea. We included all adult patients who underwent major cancer surgery between January 1, 2016, and December 31, 2018. Three lifestyle factors were evaluated preoperatively: smoking status, alcohol consumption, and physical activity.</p><p><strong>Results: </strong>A total of 48,557 patients who underwent major cancer surgery were included in the final analysis. In the multivariable logistic regression modeling, current smokers showed 1.40-fold higher odds of 90-day mortality after cancer surgery (odds ratio, 1.40; 95% confidence interval, 1.14-1.71; P = 0.001) than never smokers. However, alcohol consumption and physical activity were not associated with 90-day mortality after cancer surgery. In the multivariable Cox regression modeling, current smokers showed 1.25-fold higher odds of 1-year mortality after cancer surgery (hazard ratio, 1.25; 95% confidence interval, 1.13-1.38; P < 0.001) than never smokers. However, alcohol consumption and physical activity were not associated with 1-year mortality after cancer surgery.</p><p><strong>Conclusion: </strong>In conclusion, current smoking was associated with worse short- and long-term survival outcomes in South Korea, though preoperative alcohol consumption and physical activity levels were not associated with mortality after cancer surgery.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seung Hee Lim, Min Jeong Kim, Won Hyuk Choi, Jin Cheol Cheong, Jong Wan Kim, Kyung Joo Lee, Jun Ho Park
{"title":"Explainable machine learning using perioperative serial laboratory results to predict postoperative mortality in patients with peritonitis-induced sepsis.","authors":"Seung Hee Lim, Min Jeong Kim, Won Hyuk Choi, Jin Cheol Cheong, Jong Wan Kim, Kyung Joo Lee, Jun Ho Park","doi":"10.4174/astr.2023.105.4.237","DOIUrl":"https://doi.org/10.4174/astr.2023.105.4.237","url":null,"abstract":"<p><strong>Purpose: </strong>Sepsis is one of the most common causes of death after surgery. Several conventional scoring systems have been developed to predict the outcome of sepsis; however, their predictive power is insufficient. The present study applies explainable machine-learning algorithms to improve the accuracy of predicting postoperative mortality in patients with sepsis caused by peritonitis.</p><p><strong>Methods: </strong>We performed a retrospective analysis of data from demographic, clinical, and laboratory analyses, including the delta neutrophil index (DNI), WBC and neutrophil counts, and CRP level. Laboratory data were measured before surgery, 12-36 hours after surgery, and 60-84 hours after surgery. The primary study output was the probability of mortality. The areas under the receiver operating characteristic curves (AUCs) of several machine-learning algorithms using the Sequential Organ Failure Assessment (SOFA) and Simplified Acute Physiology Score (SAPS) 3 models were compared. 'SHapley Additive exPlanations' values were used to indicate the direction of the relationship between a variable and mortality.</p><p><strong>Results: </strong>The CatBoost model yielded the highest AUC (0.933) for mortality compared to SAPS3 and SOFA (0.860 and 0.867, respectively). Increased DNI on day 3, septic shock, use of norepinephrine therapy, and increased international normalized ratio on day 3 had the greatest impact on the model's prediction of mortality.</p><p><strong>Conclusion: </strong>Machine-learning algorithms increase the accuracy of predicting postoperative mortality in patients with sepsis caused by peritonitis.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Lim, Jong Man Kim, Jaehun Yang, Jieun Kwon, Kyeong Deok Kim, Eun Sung Jeong, Jinsoo Rhu, Gyu-Seong Choi, Jae-Won Joh, Suk-Koo Lee
{"title":"Upper thigh skeletal muscle index predicts outcomes in liver transplant recipients.","authors":"Manuel Lim, Jong Man Kim, Jaehun Yang, Jieun Kwon, Kyeong Deok Kim, Eun Sung Jeong, Jinsoo Rhu, Gyu-Seong Choi, Jae-Won Joh, Suk-Koo Lee","doi":"10.4174/astr.2023.105.4.219","DOIUrl":"10.4174/astr.2023.105.4.219","url":null,"abstract":"<p><strong>Purpose: </strong>The skeletal muscle index (SMI) at the L3 level is widely used to diagnose sarcopenia. The upper thigh (UT) also reflects changes in whole-body muscle mass, but no study has examined this using the UT to diagnose sarcopenia in liver transplantation (LT). This study aimed to determine an optimal cut-off value for UT-SMI and investigate how sarcopenia diagnosed by UT-SMI correlates with outcomes in LT recipients.</p><p><strong>Methods: </strong>In this retrospective study of 332 LT patients from 2018 to 2020, we investigated the association between sarcopenia diagnosed by UT-SMI and patient outcomes after LT.</p><p><strong>Results: </strong>The cut-off values for UT-SMI were 38.3 cm<sup>2</sup>/m<sup>2</sup> for females (area under the curve [AUC], 0.927; P < 0.001) and 46.7 cm<sup>2</sup>/m<sup>2</sup> for males (AUC, 0.898; P < 0.001). The prevalence of sarcopenia diagnosed by UT-SMI was 33.4% in our cohort. Patient and graft survival rates in the UT-SMI sarcopenia group were significantly poorer than those in the UT-SMI non-sarcopenia group (P < 0.001 and P < 0.001). UT-SMI was an independent prognostic factor for patient survival (hazard ratio [HR], 2.182; 95% confidence interval [CI], 1.183-4.025; P = 0.012) and graft survival (HR, 2.227; 95% CI, 1.054-4704; P = 0.036) in our multivariable Cox analysis.</p><p><strong>Conclusion: </strong>We confirmed that sarcopenia diagnosed by UT-SMI is associated with outcomes in LT recipients. In addition, UT-SMI was identified as an independent prognostic factor for patient survival and graft survival. Therefore, UT-SMI could be a good option for CT-based evaluations of sarcopenia in LT recipients.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyangkyoung Kim, Han Zo Choi, Yujin Kwon, Nicos Labropoulos
{"title":"Clinical outcome of graft removal versus preservation in abdominal aortic graft infection: a systematic review and meta-analysis.","authors":"Hyangkyoung Kim, Han Zo Choi, Yujin Kwon, Nicos Labropoulos","doi":"10.4174/astr.2023.105.4.207","DOIUrl":"10.4174/astr.2023.105.4.207","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare the clinical outcomes of abdominal aortic graft infection (AGI) treated with removal of the graft <i>vs.</i> graft preservation.</p><p><strong>Methods: </strong>The electronic databases PubMed, Embase, and Cochrane Library for studies that reported on AGI were searched. Observational studies and case series of at least 10 cases that reporting on the prevalence, microbiology, and outcomes of AGI were included.</p><p><strong>Results: </strong>Our search identified 23 studies that met our inclusion criteria, reporting on a total of 873 patients who underwent open surgical repair (OSR) or endovascular aneurysm repair (EVAR). Of these patients, 833 received graft removal, and 40 received graft preservation. The prevalence of AGI was reported to be 1.0% (95% confidence interval [CI], 0.5%-1.8%) after OSR and 0.4% (95% CI, 0%-1.1%) after EVAR. The pooled estimates of 1-year, 2-year, and 5-year mortality were 28.7% (95% CI, 19.4%-38.8%), 36.6% (95% CI, 24.6%-49.5%), and 51.8% (95% CI, 38.4%-65.1%) in the graft removal group and 16.1% (95% CI, 4.1%-32.2%), 18.5% (95% CI, 5.7%-35.1%), and 50.0% (95% CI, 31.6%-68.4%) in the graft preservation group. The 30-day mortality rate's risk ratio (RR) for graft removal <i>vs.</i> preservation was 0.98 (95% CI, 0.40-2.38), while the 1-year mortality rate's RR was 3.44 (95% CI, 1.60-7.42).</p><p><strong>Conclusion: </strong>The 30-day mortality rate of AGI treatment was found to be high, whether using graft removal or preservation. In selected patients, implementing antibiotics with graft preservation as an initial management may be helpful in reducing the mortality rate.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}