Ogün Aydoğan, Muhammed Çağrı Coşkun, Ulaş Utku Şekerci, Erdem Barış Cartı
{"title":"Can proximal gastrectomy be an alternative to total gastrectomy due to its nutritional advantage? A retrospective cohort study.","authors":"Ogün Aydoğan, Muhammed Çağrı Coşkun, Ulaş Utku Şekerci, Erdem Barış Cartı","doi":"10.4174/astr.2025.108.2.79","DOIUrl":"10.4174/astr.2025.108.2.79","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to evaluate the outcomes of proximal gastrectomy (PG) compared to total gastrectomy (TG) in patients with proximal stomach cancer, focusing on nutritional advantages and overall survival.</p><p><strong>Methods: </strong>A retrospective review was conducted on 87 patients who underwent gastrectomy for stomach cancer at Adnan Menderes University from January 2016 to January 2023. Among them, 21 patients underwent PG and 32 patients underwent TG. Clinical parameters, nutritional status, postoperative gastrointestinal symptoms, and survival rates were compared between the 2 groups. Statistical analyses included the chi-square test, Student t-test, and Mann-Whitney U-test.</p><p><strong>Results: </strong>The PG group showed significantly less weight loss at 12 months (6.9 ± 5.2 kg <i>vs.</i> 17.9 ± 4.0 kg, P < 0.001) and higher albumin levels at both 6 and 12 months, postoperatively (P < 0.001). The reflux index was higher in the PG group (9.4 ± 2.4 <i>vs.</i> 5.2 ± 1.6, P < 0.001), but there was no significant difference in overall Gastrointestinal Symptom Rating Scale scores (P = 0.266). Disease-specific and overall survival were significantly better in the PG group (P = 0.004 and P = 0.003, respectively).</p><p><strong>Conclusion: </strong>PG offers significant nutritional advantages and improved survival outcomes compared to TG despite higher rates of reflux. These findings suggest that PG can be a viable, function-preserving alternative to TG for patients with proximal stomach cancer. Further large-scale, prospective studies are needed to confirm these results and ensure oncological safety.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 2","pages":"79-85"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seohee Choi, Takahiro Kinoshita, Kazutaka Obama, Katsunobu Sakurai, Naoshi Kubo, Naruhiko Ikoma, Ali Guner, Hyoung-Il Kim
{"title":"Enhanced recovery after laparoscopic distal gastrectomy using articulating laparoscopic instruments in older adults with gastric cancer: a retrospective analysis of prospectively collected data.","authors":"Seohee Choi, Takahiro Kinoshita, Kazutaka Obama, Katsunobu Sakurai, Naoshi Kubo, Naruhiko Ikoma, Ali Guner, Hyoung-Il Kim","doi":"10.4174/astr.2025.108.2.86","DOIUrl":"10.4174/astr.2025.108.2.86","url":null,"abstract":"<p><strong>Purpose: </strong>As the number of older adults with gastric cancer requiring gastrectomy has increased, it has become increasingly important to use techniques that enhance surgical safety and reduce postoperative complications in this vulnerable patient population. Articulating laparoscopic instruments (ALIs) may improve maneuverability and precision, leading to better outcomes in older patients. This study aimed to compare postoperative outcomes of older adults undergoing laparoscopic distal gastrectomy for gastric cancer using conventional versus ALIs.</p><p><strong>Methods: </strong>This retrospective study included 147 older patients (aged ≥70 years) who underwent laparoscopic distal gastrectomy for gastric cancer between 2017 and 2024. Surgery was performed using conventional laparoscopic instruments in 61 patients and ALIs in 86 patients. The median follow-up period was 20 months.</p><p><strong>Results: </strong>Postoperative hospital stay was significantly shorter in the articulating group than in the conventional group (4.6 ± 2.0 days <i>vs.</i> 5.4 ± 2.4 days, P = 0.030). Time to first flatus was also significantly shorter in the articulating group (2.4 ± 0.7 days <i>vs.</i> 2.8 ± 1.0 days, P = 0.022). However, there were no significant differences in overall complications, major (≥grade III) complications (conventional, 1.2% <i>vs.</i> articulating, 0%; P = 0.398) overall survival, or recurrence-free survival between groups.</p><p><strong>Conclusion: </strong>The use of articulating instruments in older adults undergoing laparoscopic distal gastrectomy for gastric cancer was associated with shorter postoperative hospital stays and faster recovery of bowel function, with no apparent detrimental effects on complications, recurrence, or survival. These findings suggest that ALIs enhance recovery and possibly overall surgical outcomes in this patient population.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 2","pages":"86-92"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suhyeon Ha, Sujin Gang, Jueun Park, Hyunhee Kwon, Dae Yeon Kim, Seong Chul Kim, Jung-Man Namgoong
{"title":"The characteristics of patients who failed initial Kasai portoenterostomy and the long-term prognosis of those who underwent redo-Kasai: a retrospective observational study.","authors":"Suhyeon Ha, Sujin Gang, Jueun Park, Hyunhee Kwon, Dae Yeon Kim, Seong Chul Kim, Jung-Man Namgoong","doi":"10.4174/astr.2025.108.2.93","DOIUrl":"10.4174/astr.2025.108.2.93","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to determine the characteristics of patients with failed initial Kasai portoenterostomy (KP) and to compare the long-term prognosis of redo-KP with that of liver transplantation (LT) in these patients.</p><p><strong>Methods: </strong>The medical records of patients with biliary atresia (BA) who failed initial KP from 2010 to 2021 at a single center were retrospectively analyzed. KP failure was defined as persistent jaundice (total bilirubin concentration, ≥2.0 mg/dL) after KP or the performance of LT.</p><p><strong>Results: </strong>During the study period, 32 patients experienced initial KP failure, with 10 undergoing redo-KP and 22 undergoing LT. Redo-KP was successful in a minority of patients with failed initial KP, but the complications, particularly cholangitis, were more frequent in the redo-KP group. The long-term prognosis of redo-KP compared to LT showed that while some patients benefited from native liver survival after redo-KP, LT remains the more definitive solution for sustained liver function and survival in patients with BA.</p><p><strong>Conclusion: </strong>The only factor differing significantly between patients who underwent redo-KP and LT after failed initial KP was complications of cholangitis. Redo-KP was successful in 4 of 10 patients with failed initial KP, suggesting that redo-KP may be a treatment option in patients with BA and failed initial KP.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 2","pages":"93-97"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eden Demere Amare, Sumi Lee, Dongho Choi, Ji Hyun Shin, Kyeong Geun Lee, Kyeong Sik Kim, Hyunsung Kim, Yun Kyung Jung
{"title":"Exploring the prognostic role of cluster of differentiation 47 in patients with advanced pancreatic cancer: a comparative cohort study.","authors":"Eden Demere Amare, Sumi Lee, Dongho Choi, Ji Hyun Shin, Kyeong Geun Lee, Kyeong Sik Kim, Hyunsung Kim, Yun Kyung Jung","doi":"10.4174/astr.2025.108.2.98","DOIUrl":"10.4174/astr.2025.108.2.98","url":null,"abstract":"<p><strong>Purpose: </strong>Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a 5-year survival low of 2% in advanced cases. Despite being a fatal disease, there is a lack of a good predictor of prognosis which can aid in the management of patients. The tumor microenvironment of PDAC, including immune cells, plays a vital role in the progression and invasiveness of PDAC. Cluster of differentiation 47 (CD47) which has a \"don't eat me signal\" to macrophages through receptor signal regulatory protein alpha, prevents immune cell surveillance of cancer cells. This contributes to the immune escape and invasiveness of cancer.</p><p><strong>Methods: </strong>We obtained pancreatic cancer tissue microarray samples from 98 patients treated in Hanyang University Hospital. The diagnosis was proven by a tissue biopsy obtained after surgical resection. Immunohistochemical staining was done using CD47 antibody. Data was analyzed using R software ver. 4.3.3.</p><p><strong>Results: </strong>In a study of 98 patients with PDAC, CD47 expression (54.1%) was significantly correlated with advanced disease stage. Positive CD47 expression was associated with lower overall survival (P = 0.028) and disease-free survival (P = 0.005) in all patients. In advanced-stage patients, CD47 remained a predictor of lower overall survival (P = 0.012) and disease-free survival (P = 0.023). Multivariate analysis identified positive CD47 expression as an independent factor affecting overall survival (P = 0.048). These results emphasize CD47's prognostic relevance in PDAC, particularly in advanced stages.</p><p><strong>Conclusion: </strong>Positive CD47 expression in PDAC indicates an advanced stage of the disease and independently predicts poor outcomes. This highlights CD47's role as a crucial prognostic marker in advanced PDAC stages.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 2","pages":"98-106"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sung Hwan Hwang, Seon-Hi Shin, Yun Jin Kim, Jun Ho Lee
{"title":"Risk factors for recurrence in stage I colorectal cancer after curative resection: a systematic review and meta-analysis.","authors":"Sung Hwan Hwang, Seon-Hi Shin, Yun Jin Kim, Jun Ho Lee","doi":"10.4174/astr.2025.108.1.39","DOIUrl":"https://doi.org/10.4174/astr.2025.108.1.39","url":null,"abstract":"<p><strong>Purpose: </strong>Patients with stage I colorectal cancer (CRC) rarely experience recurrence after curative resection. Therefore, the risk factors for stage I CRC recurrence are yet to be established. We aimed to identify risk factors for stage I CRC recurrence.</p><p><strong>Methods: </strong>MEDLINE, Embase, and Cochrane Library were searched for articles published between 1990 and 2022. The pooled proportions and hazard ratios (HRs) were calculated. Fixed- or random-effect models were considered based on heterogeneity, using Cochran's Q-statistic and the I<sup>2</sup>-test.</p><p><strong>Results: </strong>Nine studies involving 19,440 patients were included. Nine analyzed risk factors were identified. T2 stage (pooled HR, 2.070; 95% confidence interval [CI], 1.758-2.438; P < 0.001; I<sup>2</sup>=0.0%), lymphovascular invasion (HR, 1.685; 95% CI, 1.420-1.999; P < 0.001; I<sup>2</sup> = 0.0%), venous invasion (HR, 1.794; 95% CI, 1.515-2.125; P < 0.001; I<sup>2</sup> = 0.0%), CEA level (HR, 1.472; 95% CI, 1.093-1.983; P = 0.011; I<sup>2</sup> = 1.8%) and rectal cancer (HR, 2.981; 95% CI, 2.378-3.735; P < 0.001; I<sup>2</sup> = 0.0%) were risk factors for the recurrence. However, the risk of recurrence in right-sided colon cancer was lower than in left-sided colon cancer. (HR, 0.712; 95% CI, 0.537-0.944; P = 0.018; I<sup>2</sup> = 0.0%). No statistically significant differences were observed in the number of harvested lymph nodes, age, and sex.</p><p><strong>Conclusion: </strong>T2 stage, lymphovascular invasion, venous invasion, CEA level, rectal cancer, and left-sided colon cancer were risk factors for recurrence in stage I CRC. Intensive monitoring and surveillance are warranted for patients with high-risk features of recurrence.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 1","pages":"39-48"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyeong Min Park, Mee Joo Kang, Sang-Jae Park, Kyu-Won Jung, Sung-Sik Han
{"title":"Epidemiology and survival analysis according to the histologic subtype of pancreatic cancer: a population-based cohort study.","authors":"Hyeong Min Park, Mee Joo Kang, Sang-Jae Park, Kyu-Won Jung, Sung-Sik Han","doi":"10.4174/astr.2025.108.1.20","DOIUrl":"10.4174/astr.2025.108.1.20","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated epidemiologic features of patients with pancreatic cancer in Korea, according to the histologic subtypes.</p><p><strong>Methods: </strong>The Korea Central Cancer Registry data on patients with pancreatic cancer from 1999 to 2019 were reviewed. The 101,446 patients with pancreatic cancer (C25 based on the International Classification of Diseases, 10th revision) were allocated according to the following morphological codes: A, endocrine; B, carcinoma excluding cystic and mucinous; C, cystic or mucinous; D, acinar cell; and E, sarcoma and soft tissue tumor.</p><p><strong>Results: </strong>The distribution of each pancreatic cancer subtype group in Korea from 1999 to 2019 was as follows: A, n = 3,101 (3.1%); B, n = 95,051 (93.7%); C, n = 2,856 (2.8%); D, n = 299 (0.3%); and E, n = 139 (0.1%). In group B, 49.2% of patients were aged >70 years, and half of them did not receive treatment within 4 months of diagnosis. In addition, only 30.9% of the patients were in the localized and regional stage in which surgical treatment was possible. Pancreatic cancer occurred more frequently in females than in males only in group C. Between 1999 and 2019, the average annual percentage changes in the age-specific incidence rates were positive in groups A (13.9%, P < 0.001), B (1.0%, P < 0.001), and C (6.5%, P = 0.025). Significant improvements in 5-year survival rates over time were observed in subtypes A, B, and C.</p><p><strong>Conclusion: </strong>The subgroups of pancreatic cancer show different epidemiologic features, including incidences, treatment rates, and prognoses.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 1","pages":"20-30"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Metin Bozkaya, Ebru Menekşe, Hikmet Pehlevan Özel, Yasir Keçelioğlu, İbrahim Doğan
{"title":"Investigation of the effect of perioperative parathyroid autotransplantation in incidental parathyroidectomy cases on the development of postoperative hypocalcemia: a retrospective observational study.","authors":"Metin Bozkaya, Ebru Menekşe, Hikmet Pehlevan Özel, Yasir Keçelioğlu, İbrahim Doğan","doi":"10.4174/astr.2025.108.1.64","DOIUrl":"10.4174/astr.2025.108.1.64","url":null,"abstract":"<p><strong>Purpose: </strong>One of the most common and significant complications following thyroid surgery is postoperative hypocalcemia due to postoperative hypoparathyroidism. This study aimed to observe the effect of parathyroid gland autotransplantation on postoperative hypocalcemia in cases of incidental parathyroidectomy in total thyroidectomy cases.</p><p><strong>Methods: </strong>Patients who underwent bilateral total thyroidectomy surgery were retrospectively analyzed. Patients in the study population were divided into group A (no incidental parathyroidectomy), group B (incidental parathyroidectomy with no autotransplantation), and group C (incidental parathyroidectomy with autotransplantation). The patients' calcium levels on day 1, transient and permanent hypocalcemia times, time to return to normocalcemia, and surgery duration were examined.</p><p><strong>Results: </strong>A total of 647 patients meeting the research criteria were included in the study. Group A consisted of 443 patients (68.5%), group B consisted of 176 patients (27.2%), and group C consisted of 28 patients (4.3%). The rate of incidental parathyroidectomy in the entire patient population was 31.5% (n = 204). Transient and permanent hypocalcemia rates in the entire patient population were 27.7% (n = 178) and 0.6% (n = 4), respectively. It was observed that the frequency of day 1 hypocalcemia was higher in group B than in group C among incidental parathyroidectomy groups (P = 0.005). Furthermore, group B had a significantly higher frequency of transient hypocalcemia compared to group C (P = 0.006). There was no significant difference in terms of permanent hypocalcemia.</p><p><strong>Conclusion: </strong>This study showed that parathyroid gland autotransplantation reduces transient hypocalcemia in patients with 2 or fewer incidental parathyroids.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 1","pages":"64-70"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyeung-Min Park, Jaram Lee, Soo Young Lee, Suk Hee Heo, Yong Yeon Jeong, Hyeong Rok Kim, Chang Hyun Kim
{"title":"Optimal extent of lymph node dissection in clinical early-stage right colon cancer: a retrospective analysis.","authors":"Hyeung-Min Park, Jaram Lee, Soo Young Lee, Suk Hee Heo, Yong Yeon Jeong, Hyeong Rok Kim, Chang Hyun Kim","doi":"10.4174/astr.2025.108.1.49","DOIUrl":"https://doi.org/10.4174/astr.2025.108.1.49","url":null,"abstract":"<p><strong>Purpose: </strong>Determining the extent of radical lymphadenectomy at clinical early stage is challenging. We aimed to investigate the appropriate extent of lymphadenectomy in clinical early-stage right colon cancer.</p><p><strong>Methods: </strong>Patients with clinical stage 0 or I right colon cancer who underwent curative surgery from January 2007 to December 2021 were included in this retrospective study. The extent of lymph node (LN) metastases based on the distribution of LN metastases (LND: LND1 pericolic nodes, LND2 intermediate nodes, LND3 apical nodes), along with the depth of submucosal (SM) invasion (classed into SM1-3), were analyzed.</p><p><strong>Results: </strong>Of the 348 patients, distribution across pathologic stages was as follows: 30 patients (8.6%) at stage 0, 207 (59.5%) at stage I, 52 (14.9%) at stage II, and 59 (17.0%) at stage III. In pT1 tumor patients, LN metastases varied by SM invasion depth: 3.6% in SM1 (all LND1), 5.1% in SM2 (all LND1), and 17.5% in SM3 (LND1 10%, LND2 5%, LND3 2.5%). For pT2, pT3, and pT4 stages, LN metastasis rates were 16.2% (LND1 11.3%, LND2 3.8%, LND3 1.3%), 39.7% (LND1 28.9%, LND2 8.4%, LND3 2.4%), and 50% (LND1 25%, LND2 25%), respectively. Tumor invasion depth and lymphovascular invasion were identified as significant risk factors for LN metastasis extending to LND2-3.</p><p><strong>Conclusion: </strong>Complete mesocolic excision should be considered for right-sided colon cancer because tumor infiltration deeper than SM2 could metastasize to LND2 or further. If preoperative endoscopy confirms SM1 or SM2 invasion, D2 lymphadenectomy could be a limited surgical option.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 1","pages":"49-56"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eunju Jang, Mi-Hyeong Kim, Jeong-Kye Hwang, Sun Cheol Park, Sang Seob Yun, Myung Duk Lee, Jae Hee Chung
{"title":"Evaluation of health-related quality of life and performance in intestinal transplant and rehabilitation patients: a cross-sectional study.","authors":"Eunju Jang, Mi-Hyeong Kim, Jeong-Kye Hwang, Sun Cheol Park, Sang Seob Yun, Myung Duk Lee, Jae Hee Chung","doi":"10.4174/astr.2025.108.1.31","DOIUrl":"https://doi.org/10.4174/astr.2025.108.1.31","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to evaluate health-related quality of life (HRQoL) in intestinal failure (IF) patients after different modes of intestinal rehabilitation.</p><p><strong>Methods: </strong>HRQoL was assessed using the generic 36-item Short Form Survey (SF-36, ver. 2) and visual analogue scale (VAS) in 6 different areas: diet, sleep, gastrointestinal (GI) symptoms, diarrhea, musculoskeletal pain, and other symptoms.</p><p><strong>Results: </strong>Twenty-two patients completed the questionnaires, of which 7 had received intestinal transplant (ITx), 9 were continuing home total parenteral nutrition (HPN), and 6 had tapered off total parenteral nutrition (TPN). SF-36 physical component summary scores were highest in the ITx group (median, 65.6; interquartile range [IQR], 31.6-80.3) compared to the HPN (median, 48.4; IQR, 44.7-66.3) or tapered group (median, 54.2; IQR, 45.2-61.6). Mental component summary scores were lowest in the ITx group (median, 48.8; IQR, 37.1-63.6), compared to the TPN (median, 60.2; IQR, 41.6-78.5) or tapered group (median, 51.0; IQR, 48.8-56.0). Differences were not significant in all items of the SF-36. VAS scores showed that patients in the ITx group showed the best results in diet (0.9), gastrointestinal (GI) symptoms (1.4), and musculoskeletal pain (2.4). There was a significant difference in sleep (P = 0.036), with the ITx (1.43) and HPN groups (1.33) showing better outcomes compared with the tapered group (4.67). Patients in the tapered group showed the least favorable results in all performance areas, except GI symptoms.</p><p><strong>Conclusion: </strong>SF-36 did not show a significant difference between the ITx, HPN, and tapered groups, but VAS showed a significant difference in sleep between groups. Further studies, including serial data, will allow a better understanding of the effects of different modes of intestinal rehabilitation.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 1","pages":"31-38"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gimin Lee, Sanghyuk Moon, Nagyeong Kim, Daeun Baek, Nak-Hoon Son, Kyeong Hwan Seo, Eunyoung Jung
{"title":"Efficacy of transversus abdominis plane block in postoperative pain management of laparoscopic totally extraperitoneal inguinal hernia repair: a propensity score-matched analysis.","authors":"Gimin Lee, Sanghyuk Moon, Nagyeong Kim, Daeun Baek, Nak-Hoon Son, Kyeong Hwan Seo, Eunyoung Jung","doi":"10.4174/astr.2025.108.1.57","DOIUrl":"https://doi.org/10.4174/astr.2025.108.1.57","url":null,"abstract":"<p><strong>Purpose: </strong>Transversus abdominis plane (TAP) block is a promising technique for postoperative pain control. In this study, we aimed to evaluate the efficacy of the TAP block in managing postoperative pain after laparoscopic totally extraperitoneal (TEP) inguinal hernia repair.</p><p><strong>Methods: </strong>In this retrospective study, medical records of patients who had received ultrasonography-guided TAP blocks after surgery from January 2019 to August 2023 were reviewed and compared with those of patients who had not received. Propensity score matching was controlled for age as a confounder. Postoperative pain levels were measured using the numeric rating scale (NRS).</p><p><strong>Results: </strong>After matching, 95 patients were included in each group. The TAP block group (2.7 <i>vs.</i> 4.0, P < 0.001) had significantly lower NRS scores immediately and early postoperative pain than the control group (1.9 <i>vs.</i> 2.5, P < 0.001). However, there was no significant difference between the 2 groups in terms of postoperative complications (P > 0.05).</p><p><strong>Conclusion: </strong>TAP block is effective and safe for managing immediate and early postoperative pain in laparoscopic TEP inguinal hernia repair and does not increase the risk of complications.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"108 1","pages":"57-63"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142997966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}