Annals of Surgical Treatment and Research最新文献

{"title":"Evaluation of feasibility and clinical outcomes of robot-assisted pancreaticoduodenectomy after neoadjuvant treatment for patients with advanced pancreatic ductal adenocarcinoma: a retrospective propensity score-matched cohort study.","authors":"Ha Eun Kim, Hye-Sol Jung, Youngmin Han, Yoon Soo Chae, Won-Gun Yun, Young Jae Cho, Wooil Kwon, Joon Seong Park, Jin-Young Jang","doi":"10.4174/astr.2025.109.2.61","DOIUrl":"10.4174/astr.2025.109.2.61","url":null,"abstract":"<p><strong>Purpose: </strong>With neoadjuvant treatment (NAT) broadening the surgical indication for advanced pancreatic cancer, the growing use of robotic platforms in pancreaticoduodenectomy (PD) necessitates the evaluation of its feasibility in advanced pancreatic cancer patients who have undergone NAT.</p><p><strong>Methods: </strong>We compared clinicopathological outcomes of advanced pancreatic cancer patients who received either robot-assisted or open PD after NAT at a tertiary hospital from 2015 to 2023. Propensity score matching was performed based on age, sex, and TNM staging.</p><p><strong>Results: </strong>Among 223 patients who received conversion surgery after NAT, 42 open PD and 14 robot-assisted PD patients were matched in a 3:1 ratio. There was a trend of shorter hospital stays (11.4 days <i>vs.</i> 9.8 days, P = 0.218) and less severe postoperative complications (21.4% <i>vs.</i> 7.1%; P = 0.227) in the robot-assisted PD group. Lymph node (LN) yield, LN metastasis rate, and R0 resection rates were similar between the 2 groups. The overall (OS) and disease-free survival (DFS) rates between the 2 groups were comparable (5-year OS rate: 55.7% <i>vs.</i> 72.7%, P = 0.264; 5-year DFS rate: 54.4% <i>vs.</i> 58.4%, P = 0.759).</p><p><strong>Conclusion: </strong>Robot-assisted PD offers comparable short-term and long-term outcomes to open PD, even in patients undergoing conversion surgery after NAT.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 2","pages":"61-70"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differentiating oncocytic carcinoma from oncocytic adenoma: a comprehensive evaluation of preoperative characteristics and diagnostic approaches in a retrospective cohort study.","authors":"Eunji Kim, Jun Hyun Park, Ji-Young Park, Sang-Woo Lee, Jin Hyang Jung","doi":"10.4174/astr.2025.109.2.105","DOIUrl":"10.4174/astr.2025.109.2.105","url":null,"abstract":"<p><strong>Purpose: </strong>Oncocytic carcinoma (OCA) has been reclassified from follicular thyroid carcinoma due to its unique features. Its rarity has resulted in limited studies on differentiating OCA from oncocytic adenoma (OA). This study aimed to compare the clinicopathologic and preoperative features of OCA and OA and evaluate the effectiveness of ultrasonography and cytology.</p><p><strong>Methods: </strong>We conducted a retrospective study involving 83 patients (23 with OCA and 60 with OA) who underwent thyroid surgery between 2011 and 2024. We reviewed clinical, ultrasonographic, cytologic, and histopathologic data to assess diagnostic performance.</p><p><strong>Results: </strong>OCA cases had larger tumors than OA in both sonographic (4.2 ± 1.7 cm <i>vs.</i> 2.7 ± 1.4 cm, P < 0.001) and pathologic measurements (3.8 ± 1.7 cm <i>vs.</i> 2.3 ± 1.4 cm, P < 0.001). K-TIRADS (the Korean Thyroid Imaging Reporting and Data System) did not effectively distinguish OCA from OA; however, ACR TI-RADS (the American College of Radiology Thyroid Imaging Reporting and Data System) categorized more OCA cases into higher-risk groups (17.4% <i>vs.</i> 1.7%, P = 0.016). Trabecular formation and intranodular vascularity were more frequent in OCA (17.4% <i>vs.</i> 1.7%, P = 0.019; 65.2% <i>vs.</i> 33.3%, P = 0.049). Cytologically, 87% of OCAs were classified as follicular neoplasms compared to 20% of OAs.</p><p><strong>Conclusion: </strong>Predicting malignancy in oncocytic neoplasms is challenging. Larger tumor size, higher ACR TI-RADS scores, and trabecular formation are potential indicators for OCA. Cytologic subcategorization within Bethesda IV suggests follicular neoplasms carry a higher malignancy risk than oncocytic neoplasms. Multicenter studies are needed to validate these findings.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 2","pages":"105-112"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five-year survival of patients with hilar cholangiocarcinoma: a single-center retrospective study.","authors":"HyeJeong Jeong, Hee Joon Kim, Soo Yeun Lim, Hyun Jeong Jeon, So Jeong Yoon, Hongbeom Kim, In Woong Han, Jin Seok Heo, Sang Hyun Shin","doi":"10.4174/astr.2025.109.2.71","DOIUrl":"10.4174/astr.2025.109.2.71","url":null,"abstract":"<p><strong>Purpose: </strong>Hilar cholangiocarcinoma is known for its poor prognosis due to late diagnosis. To achieve long-term survival, curative resection often is necessary. However, after surgical resection, the 5-year survival rates vary from 14% to 48%. The aim of this study is to evaluate the prognostic factors for long-term survival in hilar cholangiocarcinoma.</p><p><strong>Methods: </strong>Patients who underwent curative resection for hilar cholangiocarcinoma at Samsung Medical Center from January 2000 to December 2020 were included. Demographics, surgical and oncological outcomes, short-term complications, recurrence, pathologic results, and survival were analyzed. Prognostic factors were analyzed with Cox proportional hazards models.</p><p><strong>Results: </strong>A total of 449 patients diagnosed with hilar cholangiocarcinoma who underwent intent-to-treat resection at Samsung Medical Center from 2000 to 2020 were included in this study. The median disease-free survival was 19 months, and the median survival was 40 months. One-, 3-, and 5-year survival rates were 82.8%, 53.7%, and 35.8%, respectively.</p><p><strong>Conclusion: </strong>The 5-year survival rate of patients with hilar cholangiocarcinoma was 35.8% at Samsung Medical Center. Median survival was 40 months. N2 stage and tumor biology were factors affecting 5-year survival.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 2","pages":"71-80"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary tumor resection <i>vs.</i> self-expandable metallic stent in unresectable obstructive stage IV colorectal cancer: a comparative outcome study.","authors":"Chang Hyun Kim, Jae Kyun Ju, Jaram Lee, Hyeung-Min Park, Soo Young Lee, Hyeong Rok Kim, Young Eun Joo, Sung Bum Cho","doi":"10.4174/astr.2025.109.2.89","DOIUrl":"10.4174/astr.2025.109.2.89","url":null,"abstract":"<p><strong>Purpose: </strong>The selection of primary tumor resection (PTR) <i>vs.</i> self-expanding metallic stents (SEMS) in obstructive unresectable stage IV colorectal cancer (CRC) is critical, profoundly impacting patient outcome. This study evaluates the influence of PTR and SEMS on overall survival (OS) in conjunction with chemotherapy.</p><p><strong>Methods: </strong>The analysis included 137 patients with obstructive, unresectable stage IV CRC who underwent PTR or attempted SEMS placement. The primary objective was to assess the OS of patients, specifically examining how PTR and SEMS interventions influence these survival outcomes.</p><p><strong>Results: </strong>In a cohort of 137 patients with obstructive, unresectable stage IV CRC, 30 initially opted for PTR, while stent placement was attempted in 107 cases. Following 14 stent failures, which resulted in 8 diversions and 6 additional PTR interventions, exclusions due to elective surgeries led to a final analysis of 36 PTR and 72 SEMS cases. Cox regression analysis identified no significant survival advantage between PTR and SEMS interventions (hazard ratio [HR], 0.848; 95% confidence interval [CI], 0.555-1.298; P = 0.449). Critical findings highlighted that the absence of chemotherapy markedly reduced survival prospects (HR, 1.963; 95% CI, 1.200-3.211; P = 0.007). These insights were substantiated through propensity score matching.</p><p><strong>Conclusion: </strong>The comparative analysis reveals that neither PTR nor SEMS offers a definitive survival advantage in managing obstructive, unresectable stage IV CRC. However, the necessity for subsequent invasive interventions is notably lower in the PTR group.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 2","pages":"89-97"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of smoking and age on long-term recurrence after laparoscopic primary closure for duodenal ulcer perforation: a 5-year observational study.","authors":"Tae-Han Kim, Sang-Ho Jeong, Young-Joon Lee, Dong-Hwan Kim, Han-Gil Kim, Jae-Myung Kim, Jin-Kyu Cho, Seung-Jin Kwag, Ju-Yeon Kim, Young-Tae Ju, Chi-Young Jeong, Ji-Ho Park","doi":"10.4174/astr.2025.109.2.98","DOIUrl":"10.4174/astr.2025.109.2.98","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates risk factors for recurrence in patients who underwent laparoscopic primary closure (PC) for pyloroduodenal ulcer perforation (PUP).</p><p><strong>Methods: </strong>We retrospectively analyzed data from patients who underwent laparoscopic PC with or without highly selective vagotomy (HSV) for PUP at a tertiary hospital from 2010 to 2019. Demographics, surgical outcomes, proton pump inhibitor (PPI) use, <i>Helicobacter pylori</i> status, and endoscopic findings were reviewed. Long-term (5 years) endoscopic and clinical outcomes regarding ulcer and perforation recurrence, were collected.</p><p><strong>Results: </strong>A total of 139 patients were included in the analysis. Of these, 109 (78.4%) were male, and 76 (54.7%) were current smokers. Ninety-five patients (68.3%) underwent PC only, while 44 (31.7%) received PC + HSV. During the follow-up period, ulcer recurrence was observed in 19 patients (13.7%) and perforation recurrence in 9 (6.5%). In Cox proportional analysis for ulcer recurrence, smoking (hazard ratio [HR], 6.476; 95% confidence interval [CI], 1.834-22.873; P = 0.004) and older age (HR, 1.049; 95% CI, 1.012-1.088; P = 0.009) were identified as significant factors. For peptic ulcer perforation recurrence, smoking (HR, 19.129; 95% CI, 2.048-178.702; P = 0.010) and older age (HR, 1.062; 95% CI, 1.009-1.118; P = 0.021) were significant. No significant associations were found between sex, duration of PPI therapy, <i>H. pylori</i> eradication success, or surgery type and the risk of either ulcer or perforation recurrence.</p><p><strong>Conclusion: </strong>Smoking and age are important factors for recurrence following laparoscopic PC for PUP. These findings emphasize the need for smoking cessation and close postoperative monitoring.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 2","pages":"98-104"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenoma per polypectomy as a training metric in colonoscopy: a retrospective analysis of trainee progression compared to expert performance.","authors":"Young Min Song, Kyung Su Han, Byung Chang Kim, Chang Won Hong, Bun Kim, Dae Kyung Sohn","doi":"10.4174/astr.2025.109.2.113","DOIUrl":"10.4174/astr.2025.109.2.113","url":null,"abstract":"<p><strong>Purpose: </strong>This study introduced adenomas per polypectomy (APP) as a novel metric for evaluating the progression of lesion discrimination skills among colonoscopy trainees.</p><p><strong>Methods: </strong>This retrospective study was conducted at the National Cancer Center, Korea between March 2020 and February 2023. Nine colorectal surgeons who completed a structured 1-year colonoscopy training program were included, and their performance was compared with that of 5 expert endoscopists. APP was defined as the number of histologically confirmed adenomas among the total number of polypectomies performed. The APPs were calculated serially to assess changes from the beginning to the end of the training.</p><p><strong>Results: </strong>A total of 8,072 colonoscopies were performed by 9 trainees and 11,687 by 5 experts. The average APP of the 9 trainees was 67.0%, which was significantly different from the 73.9% APP of the experts (P < 0.001). The APP progression of trainees exhibited 3 phases: phase 1 (<200 cases) showed increasing polyp detection and APP; phase 2 (200-500 cases) displayed a sharp rise in the number of polypectomies but a decline in APP; and phase 3 (>500 cases) demonstrated a decrease in the number of polypectomies with a moderate rise in APP. However, even in phase 3, the trainees' APP remained significantly lower than that of the experts (69.9% <i>vs.</i> 73.9%, P = 0.027).</p><p><strong>Conclusion: </strong>APP, a measure of visual adenoma discrimination ability, undergoes 3 stages of progression during colonoscopy training. This progression suggests that the APP may serve as an additional metric for assessing the effectiveness of colonoscopy training.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 2","pages":"113-119"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related impact on liver regeneration in older donors after living-donor right hepatectomy: a propensity score-matched cohort study.","authors":"Na Reum Kim, Gi Hong Choi, Jin Sub Choi, Dai Hoon Han","doi":"10.4174/astr.2025.109.1.27","DOIUrl":"10.4174/astr.2025.109.1.27","url":null,"abstract":"<p><strong>Purpose: </strong>Given the widening of the donor pool to include patients with steatosis, small-for-size grafts, and older patients, this study examined the effect of age on liver volumetric regeneration after a donor right hepatectomy.</p><p><strong>Methods: </strong>We enrolled 33 older (≥55 years) and 277 younger (<30 years) donors who underwent donor right hepatectomy between March 2012 and December 2022. After propensity score-matched analysis, the perioperative surgical outcomes and growth rates of the remnant liver in 63 younger and 32 older donors were compared. Liver regeneration was assessed using CT volumetry for up to 6 months after surgery. Poor liver regeneration was defined as restoration of less than 80% of the original liver volume. The risk factors for poor liver regeneration were analyzed using a binary logistic regression model.</p><p><strong>Results: </strong>The mean age of older and younger donors was 58.0 and 24.3 years, respectively. Despite comparable preoperative factors, older donors showed significantly lower regeneration rates at all observed time points (1 month: 75.5% <i>vs.</i> 82.3%, P = 0.001; 3 months: 80.4% <i>vs.</i> 90.5%, P < 0.001; and 6 months: 87.9% <i>vs.</i> 95.8, P = 0.006, compared to total liver volume). A large total liver volume and older age were identified as risk factors for poor liver regeneration.</p><p><strong>Conclusion: </strong>Older donors showed a reduced capacity for liver regeneration. This finding suggests the need for the development of more conservative criteria for residual liver volume in older donors than for younger donors to ensure donor safety.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 1","pages":"27-34"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term oncologic benefit of postoperative chemotherapy in the resected ampulla of Vater cancer: hope or hype? A propensity score matching analysis.","authors":"Jae Hwan Jeong, Seung Soo Hong, Sung Hyun Kim, Ho Kyoung Hwang, Kyung Sik Kim, Chang Moo Kang","doi":"10.4174/astr.2025.109.1.15","DOIUrl":"10.4174/astr.2025.109.1.15","url":null,"abstract":"<p><strong>Purpose: </strong>The oncologic benefits of adjuvant chemotherapy for resected ampulla of Vater cancer (AoVCa) remain contentious. This study aimed to evaluate the long-term oncologic effects of postoperative adjuvant chemotherapy (PACT) in patients who underwent radical surgery for AoVCa.</p><p><strong>Methods: </strong>From 2005 to 2019, clinical and pathological data of 306 AoVCa patients who underwent pancreatoduodenectomy were retrospectively reviewed. Patients were divided into the PACT (+) and PACT (-) groups. Propensity score matching (PSM) was conducted to adjust for clinical factors.</p><p><strong>Results: </strong>The PACT (+) group (n = 124) and PACT (-) group (n = 182) showed significant differences in cancer stage, lymph node metastasis, perineural invasion, lymphovascular invasion, and cancer differentiation. Lower overall survival (OS) (P < 0.001) and disease-free survival (DFS) (P < 0.001) were observed in the PACT (+) group. After PSM, no significant differences in OS or DFS were found between the groups. Multivariate analysis identified lymph node metastasis and perineural invasion as significant prognostic factors, while PACT did not significantly impact long-term survival. Paradoxically, PACT was associated with worse outcomes in patients with favorable prognostic factors.</p><p><strong>Conclusion: </strong>This study suggests that PACT does not provide a clear oncologic benefit for resected AoVCa patients and may even be detrimental for those with favorable prognostic factors. There is an urgent need to develop effective anticancer treatments and consider tailored therapeutic approaches based on individual patient profiles. Future research should focus on long-term follow-up and the integration of precision medicine to improve outcomes for AoVCa patients.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 1","pages":"15-26"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging augmented reality for dynamic guidance in 3-dimensional laparoscopic and robotic liver surgery: a prospective case series study.","authors":"Moon Young Oh, Kyung Chul Yoon, Hyoun-Joong Kong, Taesoo Jang, Yeonjin Choi, Junki Kim, Jae-Yoon Kim, YoungRok Choi, Young Jun Chai","doi":"10.4174/astr.2025.109.1.44","DOIUrl":"10.4174/astr.2025.109.1.44","url":null,"abstract":"<p><strong>Purpose: </strong>Accurate anatomical knowledge and precise visualization are critical during liver surgery. We developed augmented reality (AR) software that overlays digital 3-dimensional (3D) models onto laparoscopic or robotic views, providing real-time visual aids for surgical navigation during 3D laparoscopic and robotic liver surgeries. This study assesses the accuracy of manual registration and the subjective perception of this AR software by the operator.</p><p><strong>Methods: </strong>Ten consecutive patients undergoing 3D laparoscopic or robotic liver surgery from December 2023 to February 2024 were selected for application of the AR software during surgery. Manual registration accuracy was quantified post-registration using the Dice similarity coefficient (DSC) to compare the stereoscopic and virtual liver images. A 6-question operator survey, using a 5-point Likert scale, was administered after each surgery to evaluate the software's helpfulness in clinical settings.</p><p><strong>Results: </strong>Seven males and 3 females (mean age, 62.4 ± 6.4 years) underwent liver surgery (3D laparoscopic, 5; robotic, 5). Surgical procedures included 4 right hemihepatectomies, 1 extended left hemihepatectomy, 1 left lateral sectionectomy, and 4 segmentectomies. The mean tumor size was 4.4 ± 2.2 cm (range, 1.0-7.5 cm). The mean DSC was 0.912 ± 0.052 (range, 0.879-0.954). The operator rated registration alignment favorably before (mean score, 3.9 ± 1.1) and after mobilization (mean score, 4.1 ± 1.2). The software was reported as very helpful overall (mean score, 4.2 ± 0.8), and in locating blood vessels (4.2 ± 0.6) and tumors (4.3 ± 0.7).</p><p><strong>Conclusion: </strong>Clinical application of the AR software during 3D laparoscopic and robotic liver surgery is feasible, with favorable registration accuracy and high operator perception of helpfulness.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 1","pages":"44-52"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of preoperative ultrasound in predicting diffuse sclerosing variant papillary thyroid carcinoma: a retrospective diagnostic accuracy study.","authors":"Buseon Kang, Hyeong Won Yu, Yoon Kong, Ja Kyung Lee, June Young Choi, Hee Young Na, So Yeon Park, Min Joo Kim, Jae Hoon Moon, Wonjae Cha, Woo-Jin Jeong, Won Woo Lee, Hunjong Lim, Sang Il Choi","doi":"10.4174/astr.2025.109.1.35","DOIUrl":"10.4174/astr.2025.109.1.35","url":null,"abstract":"<p><strong>Purpose: </strong>Diffuse sclerosing variant papillary thyroid carcinoma (DSV-PTC) is a rare and aggressive subtype of PTC. Preoperative diagnosis is challenging owing to the overlapping of imaging characteristics with those of other thyroid conditions. This study aimed to evaluate the accuracy of preoperative ultrasound (US) in predicting DSV-PTC and to identify significant diagnostic factors.</p><p><strong>Methods: </strong>This retrospective study analyzed 34 patients who were preoperatively suspected of having DSV-PTC based on US findings and later underwent thyroidectomy. Patients were divided into 2 groups based on the final histopathological diagnosis: DSV-PTC and non-DSV-PTC. Demographic, radiological, and pathological characteristics were also compared.</p><p><strong>Results: </strong>Only 32.4% of patients initially suspected of having DSV-PTC were confirmed postoperatively. Among the US features, the Korean Thyroid Imaging Reporting and Data System (K-TIRADS) score 5 was significantly associated with DSV-PTC (P = 0.038), whereas other radiological factors, including echogenicity and microcalcifications, were not. The histopathological features, such as tumor size, <i>BRAF</i> and <i>TERT</i> mutations, vascular invasion, and lymph node metastasis, showed no significant differences between the groups.</p><p><strong>Conclusion: </strong>Preoperative US has limited accuracy (32.4%) in diagnosing DSV-PTC. Because of the aggressive treatment recommendations based on preoperative suspicion, clinicians should carefully consider the limitations of imaging. Further studies incorporating fine-needle aspiration or core needle biopsy are required to improve diagnostic accuracy.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":"109 1","pages":"35-43"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}