Annual review of neuroscience最新文献_第7页

Brainstem Circuits for Locomotion. 脑干运动电路。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 Epub Date: 2022-01-05 DOI: 10.1146/annurev-neuro-082321-025137

Roberto Leiras, Jared M Cregg, Ole Kiehn

引用次数: 33

A Theoretical Framework for Human and Nonhuman Vocal Interaction. 人类与非人类声音互动的理论框架。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 DOI: 10.1146/annurev-neuro-111020-094807

Gregg A Castellucci, Frank H Guenther, Michael A Long

引用次数: 6

Human Cerebellar Development and Transcriptomics: Implications for Neurodevelopmental Disorders. 人类小脑发育和转录组学:对神经发育障碍的影响。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 DOI: 10.1146/annurev-neuro-111020-091953

Parthiv Haldipur, Kathleen J Millen, Kimberly A Aldinger

{"title":"Human Cerebellar Development and Transcriptomics: Implications for Neurodevelopmental Disorders.","authors":"Parthiv Haldipur, Kathleen J Millen, Kimberly A Aldinger","doi":"10.1146/annurev-neuro-111020-091953","DOIUrl":"https://doi.org/10.1146/annurev-neuro-111020-091953","url":null,"abstract":"Developmental abnormalities of the cerebellum are among the most recognized structural brain malformations in human prenatal imaging. Yet reliable information regarding their cause in humans is sparse, and few outcome studies are available to inform prognosis. We know very little about human cerebellar development, in stark contrast to the wealth of knowledge from decades of research on cerebellar developmental biology of model organisms, especially mice. Recent studies show that multiple aspects of human cerebellar development significantly differ from mice and even rhesus macaques, a nonhuman primate. These discoveries challenge many current mouse-centric models of normal human cerebellar development and models regarding the pathogenesis of several neurodevelopmental phenotypes affecting the cerebellum, including Dandy-Walker malformation and medulloblastoma. Since we cannot model what we do not know, additional normative and pathological human developmental data are essential, and new models are needed.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"45 ","pages":"515-531"},"PeriodicalIF":13.9,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271632/pdf/nihms-1810619.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Receptor-Ribosome Coupling: A Link Between Extrinsic Signals and mRNA Translation in Neuronal Compartments. 受体-核糖体耦合:神经元室中外部信号和mRNA翻译之间的联系。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 Epub Date: 2022-01-05 DOI: 10.1146/annurev-neuro-083021-110015

Max Koppers, Christine E Holt

{"title":"Receptor-Ribosome Coupling: A Link Between Extrinsic Signals and mRNA Translation in Neuronal Compartments.","authors":"Max Koppers, Christine E Holt","doi":"10.1146/annurev-neuro-083021-110015","DOIUrl":"https://doi.org/10.1146/annurev-neuro-083021-110015","url":null,"abstract":"Axons receive extracellular signals that help to guide growth and synapse formation during development and to maintain neuronal function and survival during maturity. These signals relay information via cell surface receptors that can initiate local intracellular signaling at the site of binding, including local messenger RNA (mRNA) translation. Direct coupling of translational machinery to receptors provides an attractive way to activate this local mRNA translation and change the local proteome with high spatiotemporal resolution. Here, we first discuss the increasing evidence that different external stimuli trigger translation of specific subsets of mRNAs in axons via receptors and thus play a prominent role in various processes in both developing and mature neurons. We then discuss the receptor-mediated molecular mechanisms that regulate local mRNA translation with a focus on direct receptor-ribosome coupling. We advance the idea that receptor-ribosome coupling provides several advantages over other translational regulation mechanisms and is a common mechanism in cell communication.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":" ","pages":"41-61"},"PeriodicalIF":13.9,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39647618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Neural Algorithms and Circuits for Motor Planning. 运动规划的神经算法和电路。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 DOI: 10.1146/annurev-neuro-092021-121730

Hidehiko K Inagaki, Susu Chen, Kayvon Daie, Arseny Finkelstein, Lorenzo Fontolan, Sandro Romani, Karel Svoboda

{"title":"Neural Algorithms and Circuits for Motor Planning.","authors":"Hidehiko K Inagaki, Susu Chen, Kayvon Daie, Arseny Finkelstein, Lorenzo Fontolan, Sandro Romani, Karel Svoboda","doi":"10.1146/annurev-neuro-092021-121730","DOIUrl":"https://doi.org/10.1146/annurev-neuro-092021-121730","url":null,"abstract":"The brain plans and executes volitional movements. The underlying patterns of neural population activity have been explored in the context of movements of the eyes, limbs, tongue, and head in nonhuman primates and rodents. How do networks of neurons produce the slow neural dynamics that prepare specific movements and the fast dynamics that ultimately initiate these movements? Recent work exploits rapid and calibrated perturbations of neural activity to test specific dynamical systems models that are capable of producing the observed neural activity. These joint experimental and computational studies show that cortical dynamics during motor planning reflect fixed points of neural activity (attractors). Subcortical control signals reshape and move attractors over multiple timescales, causing commitment to specific actions and rapid transitions to movement execution. Experiments in rodents are beginning to reveal how these algorithms are implemented at the level of brain-wide neural circuits. Expected final online publication date for the Annual Review of Neuroscience, Volume 45 is July 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"45 ","pages":"249-271"},"PeriodicalIF":13.9,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10784686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Breathing Rhythm and Pattern and Their Influence on Emotion. 呼吸节奏和模式及其对情绪的影响。

IF 12.1 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 Epub Date: 2022-03-08 DOI: 10.1146/annurev-neuro-090121-014424

Sufyan Ashhad, Kaiwen Kam, Christopher A Del Negro, Jack L Feldman

{"title":"Breathing Rhythm and Pattern and Their Influence on Emotion.","authors":"Sufyan Ashhad, Kaiwen Kam, Christopher A Del Negro, Jack L Feldman","doi":"10.1146/annurev-neuro-090121-014424","DOIUrl":"10.1146/annurev-neuro-090121-014424","url":null,"abstract":"Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain and body. The apparent simplicity of breathing belies a complex neural control system, the breathing central pattern generator (bCPG), that exhibits diverse operational modes to regulate gas exchange and coordinate breathing with an array of behaviors. In this review, we focus on selected advances in our understanding of the bCPG. At the core of the bCPG is the preBötzinger complex (preBötC), which drives inspiratory rhythm via an unexpectedly sophisticated emergent mechanism. Synchronization dynamics underlying preBötC rhythmogenesis imbue the system with robustness and lability. These dynamics are modulated by inputs from throughout the brain and generate rhythmic, patterned activity that is widely distributed. The connectivity and an emerging literature support a link between breathing, emotion, and cognition that is becoming experimentally tractable. These advances bring great potential for elucidating function and dysfunction in breathing and other mammalian neural circuits.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"45 ","pages":"223-247"},"PeriodicalIF":12.1,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840384/pdf/nihms-1849892.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9186217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-Modal Plasticity in Brains Deprived of Visual Input Before Vision. 视觉输入缺失前大脑的跨模态可塑性。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 DOI: 10.1146/annurev-neuro-111020-104222

Guillermina López-Bendito, Mar Aníbal-Martínez, Francisco J Martini

{"title":"Cross-Modal Plasticity in Brains Deprived of Visual Input Before Vision.","authors":"Guillermina López-Bendito, Mar Aníbal-Martínez, Francisco J Martini","doi":"10.1146/annurev-neuro-111020-104222","DOIUrl":"https://doi.org/10.1146/annurev-neuro-111020-104222","url":null,"abstract":"Unimodal sensory loss leads to structural and functional changes in both deprived and nondeprived brain circuits. This process is broadly known as cross-modal plasticity. The evidence available indicates that cross-modal changes underlie the enhanced performances of the spared sensory modalities in deprived subjects. Sensory experience is a fundamental driver of cross-modal plasticity, yet there is evidence from early-visually deprived models supporting an additional role for experience-independent factors. These experience-independent factors are expected to act early in development and constrain neuronal plasticity at later stages. Here we review the cross-modal adaptations elicited by congenital or induced visual deprivation prior to vision. In most of these studies, cross-modal adaptations have been addressed at the structural and functional levels. Here, we also appraise recent data regarding behavioral performance in early-visually deprived models. However, further research is needed to explore how circuit reorganization affects their function and what brings about enhanced behavioral performance.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":" ","pages":"471-489"},"PeriodicalIF":13.9,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40495732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Beyond Wrapping: Canonical and Noncanonical Functions of Schwann Cells. 超越包装:雪旺细胞的规范和非规范功能。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 DOI: 10.1146/annurev-neuro-110920-030610

Carla Taveggia, M Laura Feltri

引用次数: 7

Multiple-Timescale Representations of Space: Linking Memory to Navigation. 空间的多时间尺度表示:将记忆与导航联系起来。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 DOI: 10.1146/annurev-neuro-111020-084824

Wenbo Tang, Shantanu P Jadhav

{"title":"Multiple-Timescale Representations of Space: Linking Memory to Navigation.","authors":"Wenbo Tang, Shantanu P Jadhav","doi":"10.1146/annurev-neuro-111020-084824","DOIUrl":"https://doi.org/10.1146/annurev-neuro-111020-084824","url":null,"abstract":"When navigating through space, we must maintain a representation of our position in real time; when recalling a past episode, a memory can come back in a flash. Interestingly, the brain's spatial representation system, including the hippocampus, supports these two distinct timescale functions. How are neural representations of space used in the service of both real-world navigation and internal mnemonic processes? Recent progress has identified sequences of hippocampal place cells, evolving at multiple timescales in accordance with either navigational behaviors or internal oscillations, that underlie these functions. We review experimental findings on experience-dependent modulation of these sequential representations and consider how they link real-world navigation to time-compressed memories. We further discuss recent work suggesting the prevalence of these sequences beyond hippocampus and propose that these multiple-timescale mechanisms may represent a general algorithm for organizing cell assemblies, potentially unifying the dual roles of the spatial representation system in memory and navigation.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"45 ","pages":"1-21"},"PeriodicalIF":13.9,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021996/pdf/nihms-1878767.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9763945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Challenges of Organoid Research. 类器官研究的挑战。

IF 12.1 1区医学

Annual review of neuroscience Pub Date : 2022-07-08 Epub Date: 2022-01-05 DOI: 10.1146/annurev-neuro-111020-090812

Madeline G Andrews, Arnold R Kriegstein

引用次数: 0