Annual review of neuroscience最新文献_第10页

Unified Classification of Molecular, Network, and Endocrine Features of Hypothalamic Neurons. 下丘脑神经元分子、网络和内分泌特征的统一分类。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-02-08 DOI: 10.1146/annurev-neuro-070918-050414

Roman A Romanov, Alán Alpár, Tomas Hökfelt, Tibor Harkany

{"title":"Unified Classification of Molecular, Network, and Endocrine Features of Hypothalamic Neurons.","authors":"Roman A Romanov, Alán Alpár, Tomas Hökfelt, Tibor Harkany","doi":"10.1146/annurev-neuro-070918-050414","DOIUrl":"https://doi.org/10.1146/annurev-neuro-070918-050414","url":null,"abstract":"Peripheral endocrine output relies on either direct or feed-forward multi-order command from the hypothalamus. Efficient coding of endocrine responses is made possible by the many neuronal cell types that coexist in intercalated hypothalamic nuclei and communicate through extensive synaptic connectivity. Although general anatomical and neurochemical features of hypothalamic neurons were described during the past decades, they have yet to be reconciled with recently discovered molecular classifiers and neurogenetic function determination. By interrogating magnocellular as well as parvocellular dopamine, GABA, glutamate, and phenotypically mixed neurons, we integrate available information at the molecular, cellular, network, and endocrine output levels to propose a framework for the comprehensive classification of hypothalamic neurons. Simultaneously, we single out putative neuronal subclasses for which future research can fill in existing gaps of knowledge to rationalize cellular diversity through function-determinant molecular marks in the hypothalamus.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"42 ","pages":"1-26"},"PeriodicalIF":13.9,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-neuro-070918-050414","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36941526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Light-Sheet Microscopy in Neuroscience. 神经科学中的光片显微镜。

IF 12.1 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 DOI: 10.1146/annurev-neuro-070918-050357

Elizabeth M C Hillman, Venkatakaushik Voleti, Wenze Li, Hang Yu

{"title":"Light-Sheet Microscopy in Neuroscience.","authors":"Elizabeth M C Hillman, Venkatakaushik Voleti, Wenze Li, Hang Yu","doi":"10.1146/annurev-neuro-070918-050357","DOIUrl":"10.1146/annurev-neuro-070918-050357","url":null,"abstract":"Light-sheet microscopy is an imaging approach that offers unique advantages for a diverse range of neuroscience applications. Unlike point-scanning techniques such as confocal and two-photon microscopy, light-sheet microscopes illuminate an entire plane of tissue, while imaging this plane onto a camera. Although early implementations of light sheet were optimized for longitudinal imaging of embryonic development in small specimens, emerging implementations are capable of capturing light-sheet images in freely moving, unconstrained specimens and even the intact in vivo mammalian brain. Meanwhile, the unique photobleaching and signal-to-noise benefits afforded by light-sheet microscopy's parallelized detection deliver the ability to perform volumetric imaging at much higher speeds than can be achieved using point scanning. This review describes the basic principles and evolution of light-sheet microscopy, followed by perspectives on emerging applications and opportunities for both imaging large, cleared, and expanded neural tissues and high-speed, functional imaging in vivo.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"42 ","pages":"295-313"},"PeriodicalIF":12.1,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800245/pdf/nihms-1052828.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37407599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Motor Theory of Sleep-Wake Control: Arousal-Action Circuit. 睡眠-觉醒控制的运动理论:觉醒-动作回路。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-01-30 DOI: 10.1146/annurev-neuro-080317-061813

Danqian Liu, Yang Dan

{"title":"A Motor Theory of Sleep-Wake Control: Arousal-Action Circuit.","authors":"Danqian Liu, Yang Dan","doi":"10.1146/annurev-neuro-080317-061813","DOIUrl":"https://doi.org/10.1146/annurev-neuro-080317-061813","url":null,"abstract":"Wakefulness, rapid eye movement (REM) sleep, and non-rapid eye movement (NREM) sleep are characterized by distinct electroencephalogram (EEG), electromyogram (EMG), and autonomic profiles. The circuit mechanism coordinating these changes during sleep-wake transitions remains poorly understood. The past few years have witnessed rapid progress in the identification of REM and NREM sleep neurons, which constitute highly distributed networks spanning the forebrain, midbrain, and hindbrain. Here we propose an arousal-action circuit for sleep-wake control in which wakefulness is supported by separate arousal and action neurons, while REM and NREM sleep neurons are part of the central somatic and autonomic motor circuits. This model is well supported by the currently known sleep and wake neurons. It can also account for the EEG, EMG, and autonomic profiles of wake, REM, and NREM states and several key features of their transitions. The intimate association between the sleep and autonomic/somatic motor control circuits suggests that a primary function of sleep is to suppress motor activity.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"42 ","pages":"27-46"},"PeriodicalIF":13.9,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-neuro-080317-061813","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36912721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 99

Acoustic Pattern Recognition and Courtship Songs: Insights from Insects. 声学模式识别和求偶歌曲:来自昆虫的见解。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-02-20 DOI: 10.1146/annurev-neuro-080317-061839

Christa A Baker, Jan Clemens, Mala Murthy

引用次数: 22

Lessons from Worm Dendritic Patterning. 蠕虫树突模式的经验教训。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-04-02 DOI: 10.1146/annurev-neuro-072116-031437

Sharon Inberg, Anna Meledin, Veronika Kravtsov, Yael Iosilevskii, Meital Oren-Suissa, Benjamin Podbilewicz

引用次数: 26

Genes Involved in the Development and Physiology of Both the Peripheral and Central Auditory Systems. 参与外周和中枢听觉系统发育和生理的基因。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-01-30 DOI: 10.1146/annurev-neuro-070918-050428

Nicolas Michalski, Christine Petit

{"title":"Genes Involved in the Development and Physiology of Both the Peripheral and Central Auditory Systems.","authors":"Nicolas Michalski, Christine Petit","doi":"10.1146/annurev-neuro-070918-050428","DOIUrl":"https://doi.org/10.1146/annurev-neuro-070918-050428","url":null,"abstract":"The genetic approach, based on the study of inherited forms of deafness, has proven to be particularly effective for deciphering the molecular mechanisms underlying the development of the peripheral auditory system, the cochlea and its afferent auditory neurons, and how this system extracts the physical parameters of sound. Although this genetic dissection has provided little information about the central auditory system, scattered data suggest that some genes may have a critical role in both the peripheral and central auditory systems. Here, we review the genes controlling the development and function of the peripheral and central auditory systems, focusing on those with demonstrated intrinsic roles in both systems and highlighting the current underappreciation of these genes. Their encoded products are diverse, from transcription factors to ion channels, as are their roles in the central auditory system, mostly evaluated in brainstem nuclei. We examine the ontogenetic and evolutionary mechanisms that may underlie their expression at different sites.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"42 ","pages":"67-86"},"PeriodicalIF":13.9,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-neuro-070918-050428","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36912310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Glia-Neuron Interactions in Caenorhabditis elegans. 秀丽隐杆线虫的神经胶质细胞相互作用。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-03-18 DOI: 10.1146/annurev-neuro-070918-050314

Aakanksha Singhvi, Shai Shaham

引用次数: 45

Repeat-Associated Non-ATG Translation: Molecular Mechanisms and Contribution to Neurological Disease. 重复相关的非atg翻译:神经系统疾病的分子机制和贡献。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-03-25 DOI: 10.1146/annurev-neuro-070918-050405

Lien Nguyen, John Douglas Cleary, Laura P W Ranum

引用次数: 50

Magnetic Strategies for Nervous System Control. 神经系统控制的磁策略。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-04-02 DOI: 10.1146/annurev-neuro-070918-050241

Michael G Christiansen, Alexander W Senko, Polina Anikeeva

{"title":"Magnetic Strategies for Nervous System Control.","authors":"Michael G Christiansen, Alexander W Senko, Polina Anikeeva","doi":"10.1146/annurev-neuro-070918-050241","DOIUrl":"https://doi.org/10.1146/annurev-neuro-070918-050241","url":null,"abstract":"Magnetic fields pass through tissue undiminished and without producing harmful effects, motivating their use as a wireless, minimally invasive means to control neural activity. Here, we review mechanisms and techniques coupling magnetic fields to changes in electrochemical potentials across neuronal membranes. Biological magnetoreception, although incompletely understood, is discussed as a potential source of inspiration. The emergence of magnetic properties in materials is reviewed to clarify the distinction between biomolecules containing transition metals and ferrite nanoparticles that exhibit significant net moments. We describe recent developments in the use of magnetic nanomaterials as transducers converting magnetic stimuli to forms readily perceived by neurons and discuss opportunities for multiplexed and bidirectional control as well as the challenges posed by delivery to the brain. The variety of magnetic field conditions and mechanisms by which they can be coupled to neuronal signaling cascades highlights the desirability of continued interchange between magnetism physics and neurobiology.","PeriodicalId":8008,"journal":{"name":"Annual review of neuroscience","volume":"42 ","pages":"271-293"},"PeriodicalIF":13.9,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-neuro-070918-050241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37114848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 37

Dexterous Hand Movements and Their Recovery After Central Nervous System Injury. 中枢神经系统损伤后灵巧手运动及其恢复。

IF 13.9 1区医学

Annual review of neuroscience Pub Date : 2019-07-08 Epub Date: 2019-04-02 DOI: 10.1146/annurev-neuro-070918-050436

Tadashi Isa

引用次数: 22