呼吸节奏和模式及其对情绪的影响。

IF 12.1 1区 医学 Q1 NEUROSCIENCES
Annual review of neuroscience Pub Date : 2022-07-08 Epub Date: 2022-03-08 DOI:10.1146/annurev-neuro-090121-014424
Sufyan Ashhad, Kaiwen Kam, Christopher A Del Negro, Jack L Feldman
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引用次数: 0

摘要

呼吸是一种重要的有节奏的运动行为,对大脑和身体有着惊人的广泛影响。呼吸的明显简单性掩盖了一个复杂的神经控制系统,即呼吸中心模式发生器(bCPG),该系统表现出多种操作模式来调节气体交换并协调呼吸与一系列行为。在这篇综述中,我们重点介绍了我们对bCPG理解的一些进展。bCPG的核心是前Bötzinger复合体(preBötC),它通过一种出乎意料的复杂突现机制驱动吸气节奏。前BötC韵律生成的同步动力学为系统注入了鲁棒性和不稳定性。这些动态由整个大脑的输入调节,并产生广泛分布的有节奏、有模式的活动。这种联系和新兴的文献支持了呼吸、情绪和认知之间的联系,这种联系在实验上变得容易处理。这些进展为阐明呼吸和其他哺乳动物神经回路的功能和功能障碍带来了巨大的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Breathing Rhythm and Pattern and Their Influence on Emotion.

Breathing Rhythm and Pattern and Their Influence on Emotion.

Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain and body. The apparent simplicity of breathing belies a complex neural control system, the breathing central pattern generator (bCPG), that exhibits diverse operational modes to regulate gas exchange and coordinate breathing with an array of behaviors. In this review, we focus on selected advances in our understanding of the bCPG. At the core of the bCPG is the preBötzinger complex (preBötC), which drives inspiratory rhythm via an unexpectedly sophisticated emergent mechanism. Synchronization dynamics underlying preBötC rhythmogenesis imbue the system with robustness and lability. These dynamics are modulated by inputs from throughout the brain and generate rhythmic, patterned activity that is widely distributed. The connectivity and an emerging literature support a link between breathing, emotion, and cognition that is becoming experimentally tractable. These advances bring great potential for elucidating function and dysfunction in breathing and other mammalian neural circuits.

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来源期刊
Annual review of neuroscience
Annual review of neuroscience 医学-神经科学
CiteScore
25.30
自引率
0.70%
发文量
29
期刊介绍: The Annual Review of Neuroscience is a well-established and comprehensive journal in the field of neuroscience, with a rich history and a commitment to open access and scholarly communication. The journal has been in publication since 1978, providing a long-standing source of authoritative reviews in neuroscience. The Annual Review of Neuroscience encompasses a wide range of topics within neuroscience, including but not limited to: Molecular and cellular neuroscience, Neurogenetics, Developmental neuroscience, Neural plasticity and repair, Systems neuroscience, Cognitive neuroscience, Behavioral neuroscience, Neurobiology of disease. Occasionally, the journal also features reviews on the history of neuroscience and ethical considerations within the field.
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