{"title":"Spontaneous Hymenolepis nana infection in a breeding colony of nude mice.","authors":"P Hauff, W Arnold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The spontaneous occurrence of a parasitic infection with the dwarf tapeworm Hymenolepis nana is nude mice was observed under conventional conditions. Clinical, pathological and histological observations are described.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 3","pages":"133-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13550840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Septic arthritis--an experimental animal model useful in free oxygen radical research.","authors":"W E Linhart, S Spendel, G Weber, S Zadravec","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An experimental animal model for bacterial joint inflammation has been tested. Using 16 rabbits divided into 4 groups, we injected knee joints of two groups with Staphylococcus aureus and the other 2 with NaCl. One group in each was also injected with superoxide dismutase (SOD). A technique was developed which allowed frequent standardized aspirations of the joints carried out through the patella tendon. By this means, we aspirated 16 joints 112 times over 72 h, obtaining estimates of the activity of intra-articularly injected SOD. TBA-reactive substances (TBARS) measured in joint fluid and plasma were different in each of the groups, with the highest values found in animals with septic arthritis treated with SOD. Leucocyte and differential blood cell counts were checked at 12 hour intervals.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 2","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13503322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trichospirura leptostoma: a possible cause of wasting disease in the marmoset.","authors":"R Pfister, K Heider, B Illgen, R Beglinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An outbreak of wasting disease-like syndrome in a marmoset colony was found to have been caused by a nematode. After passing through several larval stages in an intermediate host, the cockroach, the parasite inhabited the pancreas of the marmoset. The cardinal symptoms were emaciation, anaemia, and elevated hepatic enzyme activities; the pancreas reacted with a fibrosing inflammation.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 4","pages":"157-61"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13276662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U Gothe, L Wollweber, G Gothe, E Anders, R Lauterbach
{"title":"A simple immunotest for monitoring the egg maturation in rainbow trout (Oncorhynchus mykiss).","authors":"U Gothe, L Wollweber, G Gothe, E Anders, R Lauterbach","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>On the principle of the single-radial-immunodiffusion a method has been developed to estimate serum vitellogenin quantitatively in maturing rainbow trouts. Serum vitellogenin (VG) content correlates with the egg diameters. Thus it is possible both to establish the beginning of the egg maturation and to monitor it in a simple way.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 5","pages":"241-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13279750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J P van Bergeijk, H van Herck, S F de Boer, G W Meijer, A P Hesp, J van der Gugten, A C Beynen
{"title":"Effects of group size and gentling on behaviour, selected organ masses and blood constituents in female Rivm: TOX rats.","authors":"J P van Bergeijk, H van Herck, S F de Boer, G W Meijer, A P Hesp, J van der Gugten, A C Beynen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of group size (individually versus 3 in a cage) and gentling on behaviour and blood constituents were studied in female rats. Gentled rats showed less freezing and/or escaping when approached in an objective handling test than non-gentled rats; the type of caging had no significant influence. In a small field, gentled rats displayed significantly more turning and standing upright, whereas these parameters did not differ between rats housed either individually or three in a cage. In both tests, gentled rats produced significantly less urine than did control rats. Neither caging nor gentling significantly influenced the group mean values and variance of masses of adrenals, spleen and thymus and plasma concentrations of glucose, cholesterol, triglycerides and corticosterone. Removal of a cage from the rack and getting out a rat caused increase in plasma concentrations of corticosterone in its remaining cage mates.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 2","pages":"85-90"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13295197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Metabolism of 14C-labeled urea in conventional and bacteria-free guinea pigs].","authors":"N C Juhr, J Franke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This report deals with the utilization of 14C-labeled urea in antibiotically decontaminated, bacteria-free guinea pigs using intragastric resp. intraperitoneal administration route. With conventional animals 52% of the intragastrically administered 14C dose can be demonstrated in the exhaled air, 1.2% in organs and 41% in the urine. 1.8% were found in intestinal and faecal contents. In bacteria-free animals 29% of the activity appeared in the exhaled air, 52% in urine and 2% remain in the intestinal tract, feces and animal body. Intraperitoneal administration of 14C urea revealed 17% resp. 14% in the exhaled air, 72% resp. 66% in urine and 2% resp. 3% in intestinal tract, feces and animal body in conventional resp. bacteria-free guinea pigs.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 3","pages":"123-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13299506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of age and body mass of recipients on survival of transferred embryos in mice.","authors":"K Nonaka, H Sasada, J Nagai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To examine the effects of age and body mass of recipients on embryo survival during gestation, ICR embryos were transferred to nulli- or primi-parous females of 4 strains of mice. Out of 530 recipients, 383 (72.3%) produced a litter. Transfer of 3,465 embryos to 383 recipients resulted in production of 1,637 pups born alive, an overall rate of embryo survival of 47.2 +/- 1.1%. Regression analyses revealed that embryo survival decreased in older recipients and increased in heavier recipients. The results were consistent in each parity/strain group and all groups combined.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 4","pages":"193-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13390826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Kaspareit-Rittinghausen, F Deerberg, K G Rapp, A Wcislo
{"title":"Renal hypertension in rats with hereditary polycystic kidney disease.","authors":"J Kaspareit-Rittinghausen, F Deerberg, K G Rapp, A Wcislo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hereditary polycystic kidney disease (PKD) was observed in a Han:SPRD rat mutant. Cysts were of tubular origin and occurrence was more pronounced in males than in females. In male rats polycystic kidney disease was associated with a marked elevation of systolic blood pressure. Therefore this rat mutant can be considered as a laboratory animal model for renal hypertension associated with adult polycystic kidney disease in man.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 5","pages":"201-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13418677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of growth hormone on secretion of pregnancy-associated murine protein-1 (PAMP-1) in female and male rats.","authors":"J Hau, P H Jørgensen, O M Poulsen, B Bak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of 2 daily injections of human growth hormone (hGH) on serum levels of pregnancy-associated murine protein-1 (PAMP-1) was analysed in male and female Mol:WIST rats. In untreated control male rats the PAMP-1 level in the circulation is below the detection limit of rocket immunoelectrophoresis whereas females have a high serum level of PAMP-1. hGH treatment of male rats resulted in a dose-dependent increase in PAMP-1 concentration, whereas a similar treatment of female rats resulted in a significant decrease of the PAMP-1 concentration in serum. Methylprednisolone treatment either alone or in combination with hGH had no significant effect on the level of PAMP-1 in serum of male rats. It is concluded that the normal sexually determined different secretion pattern of PAMP-1 can be modified towards an intermediate pattern by administration of exogenous hGH.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 6","pages":"277-82"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13238104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A modification of the rat kidney transplantation model: reduction of experimental animals.","authors":"P Vogt, A Lipécz, K Wähling","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Inbred rats display several abnormalities of the renal arteries, which are relevant for the technique used in the kidney transplantation model. After analysis of anatomical variations of renal vascular supply in inbred Lewis rats we describe an improved standardized technique of bilateral kidney grafting. After harvesting both kidneys from the donor animal they can be transplanted into 2 recipient animals. That allows to save up to 50% of donor animals.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 3","pages":"111-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13817834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}