J P van Bergeijk, H van Herck, S F de Boer, G W Meijer, A P Hesp, J van der Gugten, A C Beynen
{"title":"Effects of group size and gentling on behaviour, selected organ masses and blood constituents in female Rivm: TOX rats.","authors":"J P van Bergeijk, H van Herck, S F de Boer, G W Meijer, A P Hesp, J van der Gugten, A C Beynen","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effects of group size (individually versus 3 in a cage) and gentling on behaviour and blood constituents were studied in female rats. Gentled rats showed less freezing and/or escaping when approached in an objective handling test than non-gentled rats; the type of caging had no significant influence. In a small field, gentled rats displayed significantly more turning and standing upright, whereas these parameters did not differ between rats housed either individually or three in a cage. In both tests, gentled rats produced significantly less urine than did control rats. Neither caging nor gentling significantly influenced the group mean values and variance of masses of adrenals, spleen and thymus and plasma concentrations of glucose, cholesterol, triglycerides and corticosterone. Removal of a cage from the rack and getting out a rat caused increase in plasma concentrations of corticosterone in its remaining cage mates.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 2","pages":"85-90"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Versuchstierkunde","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The effects of group size (individually versus 3 in a cage) and gentling on behaviour and blood constituents were studied in female rats. Gentled rats showed less freezing and/or escaping when approached in an objective handling test than non-gentled rats; the type of caging had no significant influence. In a small field, gentled rats displayed significantly more turning and standing upright, whereas these parameters did not differ between rats housed either individually or three in a cage. In both tests, gentled rats produced significantly less urine than did control rats. Neither caging nor gentling significantly influenced the group mean values and variance of masses of adrenals, spleen and thymus and plasma concentrations of glucose, cholesterol, triglycerides and corticosterone. Removal of a cage from the rack and getting out a rat caused increase in plasma concentrations of corticosterone in its remaining cage mates.
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