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Zeitschrift fur Versuchstierkunde最新文献

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[The establishment of pathogen-free colonies of Chinese and Syrian hamsters (Cricetulus griseus and Mesocricetus auratus) by foster rearing]. [寄养法建立中国和叙利亚仓鼠(灰仓鼠和auratus)无病原体菌落]。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
E Sickel
{"title":"[The establishment of pathogen-free colonies of Chinese and Syrian hamsters (Cricetulus griseus and Mesocricetus auratus) by foster rearing].","authors":"E Sickel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Naturally born (less than 5 d old) or hysterectomy-derived litters from 7 mice, 90 Chinese and 19 Syrian hamsters were fostered to conventional or gnotobiotic mouse, Chinese hamster or rat dams. Generally, Chinese hamsters and mice are able to serve mutually as foster mothers without special manipulations of dams or pups. Chinese hamsters adopted suckling mice with less problems than mice when fostering young hamsters. In correlation with sucking activity the growth of most of the mouse-fostered Chinese hamsters stopped during the first week after the pup exchange. During this phase only animals with high vitality could survive. When fostered by mice or rats, hysterectomy-derived (gnotobiotic) or newborn Chinese and Syrian hamsters survived only for few days. After initially intensive maternal care the hamster pups were increasingly neglected by the foster dams. This wellknown behavior is explained with the low sucking intensity of hamsters causing the decrease of the foster mother's maternal behaviour depending on the litter's stimuli. By this interaction between the mouse's maternity and the sucking behaviour of the hamster the success of the \"classic\" method of rearing gnotobiotic hamsters became highly chance dependent.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 1","pages":"47-55"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13293311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Modification of the teratogenesis of actinomycin D and cyclophosphamide by a Mycoplasma pulmonis infection in rats]. [肺支原体感染对放线菌素D和环磷酰胺致畸作用的影响]。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
N C Juhr, H Ratsch
{"title":"[Modification of the teratogenesis of actinomycin D and cyclophosphamide by a Mycoplasma pulmonis infection in rats].","authors":"N C Juhr,&nbsp;H Ratsch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present investigation experiments have been made on the modification of the teratogenesis by a Mycoplasma pulmonis infection in rats. Substances with known teratogenic effects (Actinomycin D, Cyclophosphamide) were used. Groups of artificially infected pregnant rats were compared with pregnant rats from the SPF unit. The present study has shown that in the group of artificially infected animals no significant increase of the teratogenic effects by Actinomycin was found. In the Cyclophosphamide-treated groups more and more serious malformations have been observed in relation to dose and day of treatment.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 6","pages":"265-70"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13304240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heart transplantation in the rat: experience with a modified technique of heterotopic grafting. 大鼠心脏移植:异位移植改良技术的经验。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
H Oesterwitz
{"title":"Heart transplantation in the rat: experience with a modified technique of heterotopic grafting.","authors":"H Oesterwitz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Heart transplantation in the rat is a frequently used model to study immunological problems of primary, vascularized allografts. A modified technique of heterotopic grafting is described in detail. The donor heart is transplanted heterotopically into the recipient with the brachiocephalic artery anastomosed to the renal artery with 10 single sutures, and the pulmonary artery to the renal vein with 2 continuous, semicircular sutures which were left untied. Both anastomoses were done end-to-end with 10-0 Ethilon. The experience with 187 rat heart transplants are reported. The time needed for one transplantation ranged from 25 to 35 min (mean 30 min). Complications like bleeding, thrombosis and primary no-function did occur in 12 out of 187 transplants (6.4%). In conclusion, this modified technique of heterotopic heart transplantation in the rat is less time consuming and highly successful.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 5","pages":"211-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13418679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comments on the work of Bundschuh, G., and Madry, M.: "atwp-mutants in an albino mouse subtype (AB/Hum-1)," Z. Versuchtierkd. 1988; 31: 249-254]. [对Bundschuh, G.和Madry, M.工作的评论:“白化小鼠亚型(AB/Hum-1)中的atwp突变体”，Z. Versuchtierkd. 1988;31日:249 - 254)。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
S Hoffmann, W Arnold
{"title":"[Comments on the work of Bundschuh, G., and Madry, M.: \"atwp-mutants in an albino mouse subtype (AB/Hum-1),\" Z. Versuchtierkd. 1988; 31: 249-254].","authors":"S Hoffmann,&nbsp;W Arnold","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 1","pages":"56"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13470375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in the intestinal microflora of normal and dystrophic BIO 8262 Nij Syrian hamsters. 正常和营养不良的bio8262 Nij叙利亚仓鼠肠道菌群的差异。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
D P Engelen, J P Koopman, M E van der Brink, M H Bakker, A M Stadhouders, H de Boer
{"title":"Differences in the intestinal microflora of normal and dystrophic BIO 8262 Nij Syrian hamsters.","authors":"D P Engelen,&nbsp;J P Koopman,&nbsp;M E van der Brink,&nbsp;M H Bakker,&nbsp;A M Stadhouders,&nbsp;H de Boer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The microflora of the gastro-intestinal tract of dystrophic BIO 8262 Nij Syrian hamsters and Kun:Sh Syrian hamsters as controls was investigated by means of culturing techniques and scanning electron microscopy. The oesophagus, forestomach, stomach, small intestine, coecum and faeces were assessed for the presence of Enterobacteriaceae, Staphylococci, Lactobacilli, Streptococci, Clostridia, Bacteroides and yeasts. The normal hamsters showed low levels of yeasts in the oesophagus, forestomach and stomach; yeasts were not present in the other compartments. Relatively low levels of Staphylococci and Enterobacteriaceae were found in all gut segments; also Bacteroides was found in low levels in the upper part of the gut. The other groups of bacteria showed relatively high levels in all segments. In dystrophic BIO 8262 Nij hamsters no Enterobacteriaceae and yeasts have been detected in the gut. Scanning electron microscopy showed no difference in adhesion between both hamsters strains.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 2","pages":"91-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13503325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[XXVIIth scientific meeting and 25th anniversary of the Society for Laboratory Animal Science. Hannover, FRG, September 25-28, 1989. Abstracts]. [xxvii]科学会议和实验动物科学学会25周年纪念。汉诺威，德国，1989年9月25-28日。摘要]。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
{"title":"[XXVIIth scientific meeting and 25th anniversary of the Society for Laboratory Animal Science. Hannover, FRG, September 25-28, 1989. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 3","pages":"S1-48"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13549454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An alternative method for the quantitative collection of faeces and urine of cats as validated by the determination of mineral balance. 一种通过测定矿物质平衡验证的定量收集猫粪便和尿液的替代方法。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
F J Pastoor, A T van't Klooster, A C Beynen
{"title":"An alternative method for the quantitative collection of faeces and urine of cats as validated by the determination of mineral balance.","authors":"F J Pastoor,&nbsp;A T van't Klooster,&nbsp;A C Beynen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Generally, in order to collect faeces and urine of cats, the animals are housed in metabolism cages with wire-mesh bases. We have developed an alternative method to collect faeces and urine quantitatively and separately, using cages with solid floors. The use of such cages allows long-term experiments to be carried out without increased risk for injury to feet or legs. Modified litter boxes were constructed so that faeces and urine were separated and the cats could bury their faeces. With the use of this method the excretion of calcium, magnesium and phosphorus by mature cats was determined. Mineral retention over a period of ten days did not differ significantly from zero, suggesting that the method developed is valid for the measurement of mineral excretion. Evidence is presented that under our experimental conditions faeces should be collected for at least five days so as to cancel out largely the impact of day-to-day variation in defecation on the variance of mineral retention.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 6","pages":"259-63"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13238102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The topography of the abdominal organs of Monodelphis domestica (Marsupialia)]. [有袋动物(Monodelphis domestica)腹部器官的地形图]。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
R Koch, H Gasse, H Wilkens
{"title":"[The topography of the abdominal organs of Monodelphis domestica (Marsupialia)].","authors":"R Koch,&nbsp;H Gasse,&nbsp;H Wilkens","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>30 adult animals (14 females, 16 males) were studied macroscopically. The main findings are as follows: 1. The intestine is without striking macroscopic features that characterize the different parts of it. A variation of position of ileum, cecum, and colon, respectively, is due to the length of their mesenteries. 2. In adult males, the intestines are displaced from their position in the caudal part of the abdomen by the urethra (the urethral diameter is even wider than that of the gut, because the wall contains masses of prostatic glandular tissue). 3. The liver is clearly divided into lobes, however, there is no notch between the quadrate lobe and the left medial lobe. The falciform ligament is regarded as the border-line between these lobes, while the gall bladder separates the quadrate lobe from the right medial lobe. 4. The spleen lies almost entirely caudal to the costal arch. It extends dorsally between the stomach and the left kidney. Along the body wall, it reaches the ventral median line and shows even a slight orientation towards the xiphoid cartilage. 5. The greater omentum may extend to the cranial end to the urinary bladder. It is extremely thin and therefore hardly visible. 6. In females, subperitoneal fat may extend from the caudo-dorsal body wall along the lateral walls down to ventral regions, in some cases even occupying a considerable part of the caudo-ventral abdomen.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 6","pages":"251-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13238962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative biochemical and genetic studies of the GOX-1 (HAO-1) and the XDH-1 polymorphism in the rat (Rattus norvegicus). 褐家鼠GOX-1 (HAO-1)和XDH-1多态性的比较生化和遗传学研究。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
B Brysch, I C Reetz, H J Hedrich
{"title":"Comparative biochemical and genetic studies of the GOX-1 (HAO-1) and the XDH-1 polymorphism in the rat (Rattus norvegicus).","authors":"B Brysch,&nbsp;I C Reetz,&nbsp;H J Hedrich","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Biochemical and genetic studies have been carried out to test whether the GOX-1 (HAO-1) and the XDH-1 polymorphism in the rat are determined by one locus or by two different closely linked loci. Besides similar migration behaviour upon electrophoresis the phenotypes of both polymorphisms share major biochemical properties such as responses to heat inactivation at 50 and 70 degrees C and isoelectric points. This suggests that they represent only one enzyme. The one-enzyme hypothesis is supported by linkage analyses performed in 50 offspring of a backcross population [(SPRD-Cu3 x BN)F1 x SPRD Cu3] and 14 LXB recombinant inbred strains (progenitor strains LEW and BN) in which not a single recombinational event can be observed. The latter finding agrees well with the GOX-1/XDH-1 distribution pattern investigated in 93 inbred strains and substrains (BENDER et al. 1984). Because of these results and due to a preferential reactivity with glycolic acid we propose to designate this polymorphism only as glycolate oxidase (GOX-1).</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 1","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13293309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herniation of the liver through the diaphragm in Mol: WIST rats. Mol: WIST大鼠肝膈疝。
Zeitschrift fur Versuchstierkunde Pub Date : 1990-01-01
E Kristiansen
{"title":"Herniation of the liver through the diaphragm in Mol: WIST rats.","authors":"E Kristiansen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The occurrence of herniation of liver through the diaphragm in Mol: WIST rats from toxicological studies conducted over a period of approximately 15 years at the Institute of Toxicology, National Food Agency, Denmark, is described. The incidence of diaphragmatic hernia in male rats indicates a tendency toward an increase through the years. The long term carcinogenicity studies initiated in 1971, 1976 and 1982 (age of the rats at necropsy approximately 2 1/2 year) revealed no diaphragmatic hernias in the 1971 study and 4% in both the 1976 and the 1982 study. In females, 0%, 1% and 1% respectively with diaphragmatic hernias were found. Among the animals from two one-year studies, only with male rats, initiated in 1985 and 1987 respectively, 7% and 5% of the males had diaphragmatic hernias.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"33 3","pages":"120-2"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13298951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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