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Bladder catheterization and a plasma prostate-specific antigen in patients with benign prostatic hyperplasia and complete urine retention. 膀胱导尿和血浆前列腺特异性抗原在良性前列腺增生和完全尿潴留患者中的应用。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-04-01
S Dutkiewicz, K Stepień, A Witeska
{"title":"Bladder catheterization and a plasma prostate-specific antigen in patients with benign prostatic hyperplasia and complete urine retention.","authors":"S Dutkiewicz,&nbsp;K Stepień,&nbsp;A Witeska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nineteen men with BPH (benign prostatic hyperplasia) were studied who had up to 6 months prior to complete urine retention PSA levels measured (PSA I). Subsequent PSA levels were obtained at 2 weeks post catheterization upon catheter removal (PSA II) and at 4 (PSA III) and 6 weeks post catheterization (PSA IV). Analysed were 18 mean PSA values [ng/ml] (as one patient was found to have prostatic cancer and his data were discarded): PSA I - 6.46, PSA II - 14.26, PSA III - 9.83 and PSA IV - 7.47. Initial data suggest that the irritation of the adenoma by the catheter may cause PSA levels to rise.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 2","pages":"71-3"},"PeriodicalIF":0.0,"publicationDate":"1995-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19899047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does lead acetate intoxication damage acinar cell nuclei in the rat pancreas? ultrastructural observations. 醋酸铅中毒对大鼠胰腺腺泡细胞核有损伤吗?超微结构的观察。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-04-01
A Andrzejewska, B Szynaka, W Stokowska, P Szynaka
{"title":"Does lead acetate intoxication damage acinar cell nuclei in the rat pancreas? ultrastructural observations.","authors":"A Andrzejewska,&nbsp;B Szynaka,&nbsp;W Stokowska,&nbsp;P Szynaka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the paper is to make an ultrastructural analysis of the nuclei of the pancreatic acinar cells in the rat in the course of lead acetate intoxication. The experiment used 84 Wistar rats, divided into 3 experimental groups, and a control group. The experimental rats were given aqueous solution of lead acetate in a dose of 50 mg/dm3 in group I, 500 mg/dm3 in group II and 1000 mg/dm3 in group III. The control rats were given tap water. The animals were killed 2,4 and 6 weeks after the experiment. The pancreatic tissue was collected for ultrastructural analysis and lead level was determined in the blood and in dry pancreatic mass in an atomic absorption spectrometer. After 6 weeks of lead acetate administration the levels increased 5 to 10-fold compared with the control group. It was ultrastructurally demonstrated that a low dose of lead caused chromatin margination, extension of perinuclear space and folding of acinar cell nucleus contours. Chronic administration of high lead doses resulted in the formation of pseudoinclusions and intranuclear real inclusions of the lead-protein complex. The alterations provided evidence of the toxic effect of lead upon the acinar cells nuclei in the pancreas.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 2","pages":"43-6"},"PeriodicalIF":0.0,"publicationDate":"1995-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19899040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ozonotherapy. 臭氧疗法。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-04-01
P Madej, Z Antoszewski, J A Madej
{"title":"Ozonotherapy.","authors":"P Madej,&nbsp;Z Antoszewski,&nbsp;J A Madej","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The medical use of ozone intraarterially, subcutaneously, intramuscularly and externally and in autohaemotransfusion or as a gas introduced into body cavities, as well as drops, compresses or liquids for rinsing etc. brings about very good therapeutic results. Ozone exerts a positive effect on oxygen and nutrient supply of cells, it enhances immunological processes, inhibits inflammatory processes, has a bacterio-, fungi- and virusostatic action when there is impaired resistance to microorganisms, improves rheological properties of the blood and exhibits no side effects in patients. Consequently ozonotherapy may be regarded asan effective method of treatment.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 2","pages":"53-6"},"PeriodicalIF":0.0,"publicationDate":"1995-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19899048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative assessment of myometrial invasion of endometrial carcinoma by transvaginal ultrasonography. 经阴道超声检查子宫内膜癌肌层浸润的术前评价。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
C G Zorlu, O Cobanoglu, E Ekici, Y Ergun, E Kuscu, O Gokmen
{"title":"Preoperative assessment of myometrial invasion of endometrial carcinoma by transvaginal ultrasonography.","authors":"C G Zorlu,&nbsp;O Cobanoglu,&nbsp;E Ekici,&nbsp;Y Ergun,&nbsp;E Kuscu,&nbsp;O Gokmen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Preoperative transvaginal ultrasonographic evaluation of myometrial invasion was performed in 33 patients with endometrial cancer and compared with histologic findings. TVU was remarkably precise in predicting deep myometrial invasion (accuracy 91.7%) but superficial myometrial invasion (sensitivity 20%). TVU was highly accurate in patients with tumours limited to the endometrium (sensitivity 100%) and the sensitivity of TVU in distinguishing nil or superficial versus deep invasion was 87.8%. TVU appears to be an efficient, economic, and practical tool for this purpose, however its limitation leads to more complex imaging techniques, especially in patients in whom preoperative irradiation or conservative management is planned.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"23-5"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19548926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment for carcinoma of the gallbladder. 胆囊癌的外科治疗。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
J A Polański, P Białek, Z Biejat, M Kisiel, H Makowska, K Filipowicz, H Kwiatkowski
{"title":"Surgical treatment for carcinoma of the gallbladder.","authors":"J A Polański,&nbsp;P Białek,&nbsp;Z Biejat,&nbsp;M Kisiel,&nbsp;H Makowska,&nbsp;K Filipowicz,&nbsp;H Kwiatkowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Carcinoma of the gallbladder has always been associated with dismal prognosis. In this study we present single institution experience in surgical treatment for gallbladder cancer obtained during last five years. Even with recent improvement in diagnostic imaging modalities gallbladder malignancies are still diagnosed too late. The choice of operative procedure for a treatment of gallbladder carcinoma still remained the open question. Carcinoma of the gallbladder is not very common disease in Europe, but some how more common in Poland. According to the National Register, based on a study from 1991, 1863 cases of death from the gallbladder carcinomas were registered [13]. At the same time 2015 new cancer cases were diagnosed and registered. These gave us a crude rate of new cases in 1991 as follows: 2.7/100,000 man and 7.7/100,000 female. Those were even higher for some voivodeships in 1988, for example: Lódź (M = 3.95/100,000, F = 10.58/100,000) and Warsaw (M = 3.15/100,000, F = 7.59/100,000). Carcinoma of the gallbladder has always been associated with dismal prognosis. This was essentially the result of the slow and asymptomatic growth of the neoplasm that infiltrates the surrounding structures, such as the portal vein, hepatic artery and liver parenchyma, making a curative surgical treatment almost impossible. So there is a general impression that no progress has been made during last 20 years in the treatment for carcinoma of the gallbladder [2, 7, 9, 12]. However, in last years, we have observed improvements in diagnostic, surgical and intensive care techniques that allowed to offer a wider range of surgical and non-surgical options to our patients [1, 3, 4, 6, 8].(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"11-3"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19548922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does combined single intravenous injection of doxorubicin and verapamil have any influence on hemodynamic parameters in rabbits? 单次静脉注射阿霉素与维拉帕米对家兔血流动力学参数有影响吗?
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
M Stepień, J Drzewoski
{"title":"Does combined single intravenous injection of doxorubicin and verapamil have any influence on hemodynamic parameters in rabbits?","authors":"M Stepień,&nbsp;J Drzewoski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The hemodynamic effects of a single intravenous injection of doxorubicin (DXR) in a dose of 3 mg/kg, verapamil (Vp) in a dose of 0.2 mg/kg and combined administration of the same doses of both drugs in rabbits were investigated. Cardiac output (CO), stroke volume (SV), heart rate (HR), mean arterial pressure (MAP) and total peripheral resistance (TPR) were estimated before and repeated in the 1st, 15th, 30th, 45th, 60th, 90th and 120th minute after injection of the drugs. It was found that administration of Vp after DXR or DXR after Vp produced significant decrease of MAP. However, no significant changes of CO, SV, HR and TPR in rabbits treated with DXR and Vp were noted. Rhythm disturbances occurred in animals receiving DXR or DXR with Vp. The obtained results indicate the need for further experimental studies before the introduction of combined treatment with DXR and Vp to cancer patients.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"19-22"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19548924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zinc and magnesium serum levels in patients with benign prostatic hyperplasia (BPH) before and after prazosin therapy. 吡唑嗪治疗前后良性前列腺增生(BPH)患者血清锌、镁水平的变化。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
S Dutkiewicz
{"title":"Zinc and magnesium serum levels in patients with benign prostatic hyperplasia (BPH) before and after prazosin therapy.","authors":"S Dutkiewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 32 patients with benign prostatic hyperplasia (BPH) serum levels of zinc and magnesium were studied before and after prazosin therapy with (Minipress-Pfizer), 4 mg daily. Following cessation of therapy a slight increase in Zn levels was observed, i.e. from 99.79 to 103.29 micrograms/dl, whereas Mg levels did not change significantly (1.95 and 1.94 mg/dl, respectively). In comparison with other organs, the human prostate is characterized by high Zn and Mg content. In BPH the Zn levels are increased. They are markedly decreased in carcinoma of the prostate and in prostatitis [4, 5]. Zn and Mg play an important role as catalysts in various enzymatic reactions. It has been postulated that changes in concentrations of these two elements are parallel [6]. Kvist has found that Zn imparts resistance to detergent-induced decondensation of spermatozoon nuclear chromatin. The effect was more pronounced with higher Zn concentrations in a buffer fluid. Other bivalent cations were found to be ineffective in stabilizing nuclear chromatin under such conditions. A possible role for seminal zinc in prevention of the reduction of disulfide cross-links and nuclear decondensation was postulated [2]. Zinc also plays an important role in protein synthesis. Zinc ions inhibit androgen metabolism in the prostate. Physiologic Zn serum levels are equal to or above 90 micrograms/dl [4, 6]. Magnesium, unlike zinc, is uniformly distributed within different areas of the gland. In BPH, both normal and increased Mg levels in the prostate have been reported [6]. Mg plays an important role as an activator of enzymes (phosphatases) involved in ATP metabolism, thus affecting both katabolic and anabolic processes.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"15-7"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19548923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Rett syndrome. A case report. 雷特综合症。一份病例报告。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
A Aydogan, G Inan, S Pinarli
{"title":"The Rett syndrome. A case report.","authors":"A Aydogan,&nbsp;G Inan,&nbsp;S Pinarli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A rare case of a 40 month old girl has been diagnosed clinically to be that of the Rett syndrome, i.e. demonstrating regression in the development, repetitive handwringing movements and inability to speak. There were no specific laboratory findings.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"27-8"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19548927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The activity of glucose-6-phosphate dehydroxygenase and glutathione enzymes in red blood cells in patients with haemoblastoses. 葡萄糖-6-磷酸脱氢酶和谷胱甘肽酶在造血干细胞患者红细胞中的活性。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
A Kumerova, A Silova, A Lece, V Petuchov
{"title":"The activity of glucose-6-phosphate dehydroxygenase and glutathione enzymes in red blood cells in patients with haemoblastoses.","authors":"A Kumerova,&nbsp;A Silova,&nbsp;A Lece,&nbsp;V Petuchov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The activity of glucose-6-phosphate dehydrogenase (G6PD), glutathione reductase (GSSG-R), glutathione peroxidase (GSH-Px) and MDA levels have been assayed in red blood cells (RBC), obtained from 57 people suffering from haemoblastoses. The activities of G6PD in the RBC in patients with polycythemia vera (PV) and chronic lymphoid leukemia (CML) are significantly higher than those in healthy patients. Changes in the activity of glutathione dependent enzymes GSSG-R and those of GSH-Px in the RBC go in opposite directions: the activity of GSSG-R is significantly enhanced in patients with PV and CML, but the activity of GSH-Px is decreased in all patients suffering from haemoblastoses. The high levels of MDA in the RBC of all patients with haemoblastoses indicate intensification of lipid peroxidation in their RBC.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19550182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benign prostatic hyperplasia. Current strategy and pharmacotherapeutical potential. 良性前列腺增生。目前的策略和药物治疗潜力。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1995-01-01
S Dutkiewicz
{"title":"Benign prostatic hyperplasia. Current strategy and pharmacotherapeutical potential.","authors":"S Dutkiewicz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"27 1","pages":"3-6"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19548930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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