Surgical treatment for carcinoma of the gallbladder.

J A Polański, P Białek, Z Biejat, M Kisiel, H Makowska, K Filipowicz, H Kwiatkowski
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Abstract

Carcinoma of the gallbladder has always been associated with dismal prognosis. In this study we present single institution experience in surgical treatment for gallbladder cancer obtained during last five years. Even with recent improvement in diagnostic imaging modalities gallbladder malignancies are still diagnosed too late. The choice of operative procedure for a treatment of gallbladder carcinoma still remained the open question. Carcinoma of the gallbladder is not very common disease in Europe, but some how more common in Poland. According to the National Register, based on a study from 1991, 1863 cases of death from the gallbladder carcinomas were registered [13]. At the same time 2015 new cancer cases were diagnosed and registered. These gave us a crude rate of new cases in 1991 as follows: 2.7/100,000 man and 7.7/100,000 female. Those were even higher for some voivodeships in 1988, for example: Lódź (M = 3.95/100,000, F = 10.58/100,000) and Warsaw (M = 3.15/100,000, F = 7.59/100,000). Carcinoma of the gallbladder has always been associated with dismal prognosis. This was essentially the result of the slow and asymptomatic growth of the neoplasm that infiltrates the surrounding structures, such as the portal vein, hepatic artery and liver parenchyma, making a curative surgical treatment almost impossible. So there is a general impression that no progress has been made during last 20 years in the treatment for carcinoma of the gallbladder [2, 7, 9, 12]. However, in last years, we have observed improvements in diagnostic, surgical and intensive care techniques that allowed to offer a wider range of surgical and non-surgical options to our patients [1, 3, 4, 6, 8].(ABSTRACT TRUNCATED AT 250 WORDS)

胆囊癌的外科治疗。
胆囊癌的预后总是很差。在这项研究中,我们介绍了在过去五年中获得的胆囊癌手术治疗的单机构经验。即使最近在诊断成像方式的改进,胆囊恶性肿瘤的诊断仍然太迟。胆囊癌手术方式的选择仍是一个悬而未决的问题。胆囊癌在欧洲不是很常见,但在波兰比较常见。根据国家登记处1991年的一项研究,登记了1863例胆囊癌死亡病例[13]。与此同时,2015年新增癌症病例被诊断和登记。这些数据为我们提供了1991年新病例的大致比率:男性每10万人中有2.7例,女性每10万人中有7.7例。在1988年的一些省份,这一比例甚至更高,例如:Lódź (M = 3.95/100,000, F = 10.58/100,000)和华沙(M = 3.15/100,000, F = 7.59/100,000)。胆囊癌的预后总是很差。这主要是由于肿瘤生长缓慢且无症状,浸润周围结构,如门静脉、肝动脉和肝实质,使得根治性手术治疗几乎不可能。因此,人们普遍认为,在过去的20年中,胆囊癌的治疗没有取得任何进展[2,7,9,12]。然而,在过去的几年里,我们观察到诊断、手术和重症监护技术的进步,为我们的患者提供了更广泛的手术和非手术选择[1,3,4,6,8]。(摘要删节250字)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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