Materia medica Polona. Polish journal of medicine and pharmacy最新文献

Adipose tissue distribution and behaviour of selected gastro-entero-pancreatic hormones, glycaemia, growth hormone and somatomedin C in obese children. 肥胖儿童的脂肪组织分布和选定的胃肠胰激素、血糖、生长激素和生长激素C的行为。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1998-01-01

B Zajadacz

引用次数: 0

Anaemia and antioxidant defence of the red blood cells. 贫血和红细胞的抗氧化防御。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1998-01-01

A Kumerova, A Lece, A Skesters, A Silova, V Petuhovs

引用次数: 0

Factors affecting surgical mortality and morbidity in patients with obstructive jaundice. 影响梗阻性黄疸手术死亡率和发病率的因素。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1998-01-01

N N Gönüllü, N Z Cantürk, N Z Utkan, C Yidirir, M Dülger

{"title":"Factors affecting surgical mortality and morbidity in patients with obstructive jaundice.","authors":"N N Gönüllü, N Z Cantürk, N Z Utkan, C Yidirir, M Dülger","doi":"","DOIUrl":"","url":null,"abstract":"The importance of clinical and laboratory parameters which have an effect on postoperative mortality and morbidity was evaluated in 124 patients operated on because of obstructive jaundice. The causes of obstructive jaundice were a malign disease in 38 patients (30.6%) and a benign disease in 86 patients (69.4%). Biliary enteric anastomosis in 66 patients (53%), external drainage in 46 patients (37%), and cholecystectomy in 12 patients (10%) were the surgical techniques of choice for correction of obstructive jaundice. There were significantly high mortality rates in patients with weight loss, more than 10 kg during preoperative the month (p < 0.05); jaundice longer than 21 days, (p < 0.001); and malignancy caused jaundice (p < 0.002). Haematocrite less than 30% (p < 0.05), albumin level below 3 g/dl (p < 0.01), blood urea nitrogen level above 30 mg/dl (p < 0.001), and bilirubine above 10 mg/dl (p < 0.01) were determined as risk factors in mortality. Direct relationships between the number of risk factors, complications, and mortality ratios were determined. One or more complications were determined in patients with more than six risk factors. High mortality rate was also determined in patients who had five and more risk factors. The following factors were evaluated: respiratory, circulatory, renal functions, and infection, and metabolic concomitant diseases, and comorbid scores for each patient were calculated. High rate complications in patients with eight and more comorbid scores and high mortality rates in patients with six and more were also determined. Finally, all these parameters were important in demonstrating postoperative mortality in obstructive jaundice patients. We suggest that surgery after treatment of correctable risk factors decreases postoperative morbidity and mortality.","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"30 1-2","pages":"6-11"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21085741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of epsilon-aminocaproylaminoacids on prothrombin activation and thrombin activity. epsilon-氨基原酰氨基酸对凝血酶原活化和凝血酶活性的影响。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1998-01-01

K Midura-Nowaczek, W Roszkowska-Jakimiec, I Bruzgo, K Worowski

引用次数: 0

Morphological changes in mitochondria and lysosomes of hepatocytes in acute intoxication with 2,4-dichlorophenoxyacetic acid (2,4-D). 2,4-二氯苯氧乙酸急性中毒后肝细胞线粒体和溶酶体的形态学改变(2,4- d)。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1998-01-01

M Sulik, W Kisielewski, B Szynaka, A Kemona, A Sulik, M Sulkowska, M Baltaziak

{"title":"Morphological changes in mitochondria and lysosomes of hepatocytes in acute intoxication with 2,4-dichlorophenoxyacetic acid (2,4-D).","authors":"M Sulik, W Kisielewski, B Szynaka, A Kemona, A Sulik, M Sulkowska, M Baltaziak","doi":"","DOIUrl":"","url":null,"abstract":"The hepatotoxic effect of 2,4-dichlorophenoxyacetic acid (2,4-D) was investigated. Ultrastructural changes were evaluated under a transmission electron microscope. Certain histoenzymatic reactions were examined (to acid phosphatase according to Gomori (AP) and to succinic dehydrogenase (SD) according to Nachlas) in parenchymal cells of the rat liver in acute intoxication induced by this herbicide. The experiment used 60 male Wistar rats divided into two groups: I-control--18 animals and II--42 animals which received chemically pure 2,4-D acid by gastric gavage in a dose of 200 mg/kg b.w. The animals were sacrificed after 12, 24, 48 hours and 4, 10 and 30 days of the experiment. The results indicate that the administration of 2,4-D acid to rats in a dose inducing acute intoxication leads to histoenzymatic and ultrastructural changes in the liver, which suggest nonspecific reversible adaptive-type damage to parenchymal cells. The changes observed indicate disorders in energetic processes in hepatocytes and are morphological exponents of intense detoxicative processes.","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"30 1-2","pages":"16-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21085744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platelet aggregation size and volume in chronic obstructive pulmonary disease. 慢性阻塞性肺疾病的血小板聚集大小和体积。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1997-01-01

I Onder, S Topcu, H S Dökmetas, C Türkay, Z Seyfikli

引用次数: 0

Fibrinogen, factor VII, antithrombin III, cholesterol and triglycerides in young men with myocardial infarction and in their sons. 纤维蛋白原，因子7，抗凝血酶III，胆固醇和甘油三酯在心肌梗死的年轻男性和他们的儿子。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1997-01-01

M Jastrzebska, B Torbus-Lisiecka, J Pieczul-Mróz, K Chełstowski, M Naruszewicz

{"title":"Fibrinogen, factor VII, antithrombin III, cholesterol and triglycerides in young men with myocardial infarction and in their sons.","authors":"M Jastrzebska, B Torbus-Lisiecka, J Pieczul-Mróz, K Chełstowski, M Naruszewicz","doi":"","DOIUrl":"","url":null,"abstract":"The concentrations of fibrinogen (Fb) and the activities of factor VII (F VIIC) and antithrombin III (AT III) both in men less than 55 years old with a history of myocardial infarction (MI) and with normolipemia (MI-NLP) or hyperlipoproteinemia (MI-HLP) and in their sons have been measured. A significantly higher levels of Fb were found in both MI groups. Significantly higher levels of F VIIC and AT III were found only in the MI-NLP group. No lipid or haemostatic disorders were noted in sons. Furthermore, a positive correlation between the level of F VIIC and triglycerides (TG) or total cholesterol (TCh) in the patients and sons was revealed. A positive correlation was found between: (a) Fb levels in MI-HLP patients and in their sons; (b) TG levels in MI-HLP patients and in their sons; and (c) AT III activity in MI patients and in their sons. Fibrinogen appears to be associated with ischemic heart disease more closely than factor VII, the latter being strongly linked with hypertriglyceridemia. Elevated activities of AT III may reflect the haemostatic response to the prothrombotic state in IHD on the one hand whereas they may contribute to the development of IHD on the other.","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"29 1-4","pages":"3-7"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21085157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidermoid carcinoma of the male urethra. Case report. 男性尿道表皮样癌。病例报告。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1997-01-01

G Ozdemir, Z E Günes, S Sargin, A Yazicoglu, H Ozdemir

引用次数: 0

Burch bladder neck colposuspension, comparison of early and late results. Burch膀胱颈部悬吊，早期与晚期结果比较。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1997-01-01

N Mutlu, M Kazado, M Culha, E Merder, M Baykal, N Canbazoglu

{"title":"Burch bladder neck colposuspension, comparison of early and late results.","authors":"N Mutlu, M Kazado, M Culha, E Merder, M Baykal, N Canbazoglu","doi":"","DOIUrl":"","url":null,"abstract":"Purpose: Suprapubic or endoscopic Burch colposuspension is a preferred technique for the treatment of stress urinaly incontinence in selective cases. We have attempted to investigate the early and long term results of suprapubic surgery for the treatment of stress incontinence and cystocele.Patients and method: 98 patients with grade 1-2 stress urinary incontinence and grade 1-2 cystocele were included in this study. Preoperative testing include the Boney test, pad test, cystography, cystometry, leak point pressure, and urethral pressure profile studies.Results: Our success rate was 93% three months after surgery for stress incontinence, 81% after twelve months (range 11 to 14) and 67% after 48 months (range 44-55). Grade 1 cystocele was corrected with a 76% success rate and Grade 2 cystocele was corrected with a 70% success rate 3 months after surgery. Twelve months later, these rates were 68% and 56% respectively. At the time of the last control these rates were 59% and 37% for cystocele, respectively.Conclusion: Burch colposuspension is an effective method for the treatment of Grade 1-2 stress incontinence and grade 1 cystocele in the early and late control examinations, but is not effective in patients with grade 2 cystocele in the long-term follow up examinations.","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"29 1-4","pages":"8-10"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21085158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Release of human monocytes protein C and the cofactor protein S in vitro. 人单核细胞蛋白C和辅助因子蛋白S的体外释放。

Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1997-01-01

J Giedrojć, J Kłoczko, A Szpak, P Radziwon, M Klimiuk, J Zuk, M Bielawiec, H K Breddin

{"title":"Release of human monocytes protein C and the cofactor protein S in vitro.","authors":"J Giedrojć, J Kłoczko, A Szpak, P Radziwon, M Klimiuk, J Zuk, M Bielawiec, H K Breddin","doi":"","DOIUrl":"","url":null,"abstract":"Monocytes may contribute to a coagulation process by expression of the tissue factor and by synthesizing factors V, VII, X and XIII. Cultured blood monocytes also express both the tissue plasminogen activator and the plasminogen activator inhibitor I. The present study assesses the ability of human monocytes to secrete protein C and its cofactor protein S, which are potent inhibitors of the clotting cascade. Monocytes derived from the blood of healthy volunteers and prepared according to Boyum were cultured for up to 36 hours with or without lipopolisaccharide from Escherichia coli. After different times of incubation, the concentrations of proteins C and S in the supernatants were measured in order to determine synthesis of proteins, monocytes were cultured in the presence or absence of cycloheximide, the protein synthesis inhibitor. The concentration of protein C was estimated by means of the ELISA Protein C test (Boehringer Mannheim). Protein S concentrations were measured by rocket immunoelectrophoresis according to Laurell, using monospecific antisera (American Diagnostica Inc., N.Y.). The study showed that human monocytes, when stimulated by lipopolisaccharide, release proteins C and S in vitro. The concentration of these proteins in the culture supernatants markedly increased with time during the 36-hour observation. The supernatants obtained from the culture of unstimulated monocytes did not contain detectable quantities of the investigated proteins. The exposure of the cells to cycloheximide did not suppress the release of proteins C and S. In conclusion, our results suggest that monocytes are not able to synthesize proteins C and S. They can only release these factors. Furthermore, monocytes may be responsible for coagulation due to the inactivation of factors Va and VIIIa by protein C.","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"29 1-4","pages":"14-6"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21085159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0