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Optimal control of intermittent normal conduction in a tachycardia-dependent right bundle branch block. 心动过速依赖性右束支传导阻滞间歇正常传导的优化控制。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-10-01
K Izumi
{"title":"Optimal control of intermittent normal conduction in a tachycardia-dependent right bundle branch block.","authors":"K Izumi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tachycardia-dependent right bundle branch block (RBBB) with atrial fibrillation in a patient under digitalis therapy is presented, in which supernormal phase of intraventricular conduction was well-documented. The development of long intervals terminated by a normally conducted beat was attributed to the occurrence of concealed atrio-ventricular (A-V) conduction of the atrial fibrillation impulse during the supernormal phase. The ventricular interval caused by a normally conducted beat (xs) in the interval of 1.01-1.63 s was transformable into a vector differential equation dy/dx = In (x + a) + 1, where parameter a = 0, 0.04, 0.08, 0.16, and 0.24. This is piecewise continuous and integrable. The function in (x + 0.04) + 1 was considered to give the solution of the problem of optimal control, which is equivalent to the problem of finding Green's function of the region, i.e. to solving the Dirichlet problem. The solution curves, given by y = (x + a) in (x + a) + 1, can be interpreted as distributions. There were structurally stable vector field points on a differentiable manifold, i.e, attractors. In general, the modelling may be applicable to tachycardia-dependent RBBB.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 4","pages":"141-8"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20247804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoglobulin A--alpha-1-antitrypsin complex in rheumatic diseases. 免疫球蛋白A- α -1-抗胰蛋白酶复合物在风湿病中的作用。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-10-01
J K Lacki, K Klama, S H Mackiewicz
{"title":"Immunoglobulin A--alpha-1-antitrypsin complex in rheumatic diseases.","authors":"J K Lacki,&nbsp;K Klama,&nbsp;S H Mackiewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immunoglobulin A-alpha-1-antitrypsin complex (IgA-AT) is a nonimmune complex formed by disulphide bonding between an active thiol group available on the cysteine residue of alpha heavy chains of IgA and a cysteine in position 232 of alpha l-antitrypsin in single polypeptide chain. The level of the complex can easy be determined using the ELISA method and findings are expressed in arbitrary units. In the healthy adults' sera the IgA-AT complex level is lower than 0.4 arbitrary unit. The elevated levels of the complex were found in a number of rheumatic diseases. In 50% of SLE patients, its levels are increased, particularly in those with current central nervous system involvement. Similarly, in approximately 50% sera derived from RA patients they are also found to be higher. Their presence correlates with anatomical progression of the disease. IGA-AT complex is found in RA (in 90% of cases) but not in the osteoarthritis synovial fluid. Our findings can be applied in clinical praxis in differential diagnosis of early rheumatoid arthritis and osteoarthritis. The IGA-AT complex can be also found in ankylosing spondylitis. The complex has been determined in a relatively large number of IgA myeloma sera. In 30% of the cases its levels were 10-fold higher than the upper limit for healthy adults.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 4","pages":"138-40"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20247805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intractable epilepsy in children who develop epilepsy in the first decade of life--a prospective study. 顽固性癫痫的儿童谁发展癫痫的头十年-一项前瞻性研究。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-10-01
J Czochańska, Z Losiowski, B Langner-Tyszka, J Bielicka-Cymerman, M Cendrowska, B Schmidt-Sidor, E Szczepanik, K Szymańska
{"title":"Intractable epilepsy in children who develop epilepsy in the first decade of life--a prospective study.","authors":"J Czochańska,&nbsp;Z Losiowski,&nbsp;B Langner-Tyszka,&nbsp;J Bielicka-Cymerman,&nbsp;M Cendrowska,&nbsp;B Schmidt-Sidor,&nbsp;E Szczepanik,&nbsp;K Szymańska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prospective studies on 347 children under treatment due to seizures which appeared in the first 10 years of life helped to evaluate and define the incidence of epilepsy resistant to treatment. With regard to each patient the following aspects were analysed: the kind of seizures, their etiology, accompanying neurological disorders and a type of epileptic syndrome, kind of treatment applied before admission to the clinical department as well as socioeconomic conditions of the families. Patients under study were divided into four age groups to evaluate the results. Epilepsy, which was completely resistant to treatment, was observed in 10% of the patients, partially resistant in 20%. Resistance is the outcome of the following factors: onset of epilepsy in early childhood, symptomatic etiology coexisting symptoms of CNS damage, occurrence of unfavourable epileptic syndromes such as Lennox-Gastaut, wrong selection and low dosage of drugs, inappropriate polytherapy and adverse social conditions. On the basis of the results obtained, the authors suggested point evaluation as a kind of screening in prediction of failures in treatment.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 4","pages":"133-7"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20247802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quinolinic acid: effect on neurons of the paraventricular nucleus of the hypothalamus. 喹啉酸:对下丘脑室旁核神经元的影响。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-10-01
M Beskid, J Białek, Z Rózycka
{"title":"Quinolinic acid: effect on neurons of the paraventricular nucleus of the hypothalamus.","authors":"M Beskid,&nbsp;J Białek,&nbsp;Z Rózycka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Quinolinic acid was administered intraperitoneally to male Wistar rats in a dose of 60 mmol, once daily for 8 days. The neuronal cell bodies in the paraventricular nucleus of the hypothalamus of quinolinic acid-treated rats exhibited electron microscopic features of increased cellular activity but some damage of neuronal cell bodies was also present. After quinolinic acid treatment, damaged cells predominated within the parvocellular division of the nucleus. The cells varied with respect to the degree of their damage. Besides, the cells exhibiting an increased activity, as well as those looking normally, were also present. In the magnocellular division of the nucleus, the cells exhibiting an increased activity predominated, although some forms of damage could also be distinguished.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 4","pages":"149-53"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20247807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of health resort treatment on insulin and C-peptide concentration in girls with insulin-dependent diabetes. 疗养地治疗对胰岛素依赖型糖尿病女孩胰岛素和c肽浓度的影响
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-10-01
M Bonikowska-Zgaińska
{"title":"Influence of health resort treatment on insulin and C-peptide concentration in girls with insulin-dependent diabetes.","authors":"M Bonikowska-Zgaińska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of treatment in health resorts on the behaviour of C-peptide and insulin concentrations was evaluated in serum and urine of diabetics. The group examined comprised 68 girls with insulin-dependent diabetes estimated by radioimmunological methods. The study was carried out during and after health resort treatment. C-peptide initial concentrations constituted the basis for the examined and comparative group division into the following sub-groups: A--C-peptide secretion within standard limits, B--C-peptide trace secretion, and C--patients whose C-peptide concentrations were not determined. After health resort treatment a statistically significant difference of C-peptide secretion was found in serum in the groups with the well preserved secretion and that with only traces of C-peptides. A statistically significant difference in insulin concentrations was also found. Summing up, after health resort treatment of insulin-dependent diabetics with preserved only insignificant secretion of endogenous C-peptide, the secretion of this hormone increased.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 4","pages":"115-31"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20247803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid peroxidation and activity of antioxidative enzymes in the rat model of ozone therapy. 臭氧治疗大鼠模型中脂质过氧化及抗氧化酶活性的研究。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-10-01
P Laszczyca, E Kawka-Serwecińska, I Witas, B Dolezych, B Falkus, A Mekail, B Ziółkowska, P Madej, P Migula
{"title":"Lipid peroxidation and activity of antioxidative enzymes in the rat model of ozone therapy.","authors":"P Laszczyca,&nbsp;E Kawka-Serwecińska,&nbsp;I Witas,&nbsp;B Dolezych,&nbsp;B Falkus,&nbsp;A Mekail,&nbsp;B Ziółkowska,&nbsp;P Madej,&nbsp;P Migula","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypothetical, therapeutic effects of ozone were investigated in an animal model. One ml of oxygen or mixture of 40 micrograms ozone with oxygen were injected intraperitoneally to male rats for 10 days. Previously, rats had been poisoned with 50 ppm Cd2+ in drinking water for 12 weeks. Exhaustive treadmill running was applied to some animals before sacrification. Ozone injections increased iron-ascorbate-stimulated lipid peroxidation (LPO) in the liver and kidney, catalase (CAT) activity in the heart and glutathione S-transferase (GST) activity in the heart, kidney and liver. Oxygen increased GST activity in the brain and reduced glutathione peroxidase (GPX) activity in the kidney. Cadmium enhanced LPO in the liver and GST activity in the brain, heart, kidney and liver. In contrast to ozone, cadmium inhibited GPX activity in the brain, kidney and liver. Cadmium combined with ozone enhanced the changes of GPX activity in the kidney and liver, that of GST activity in the heart, kidney and liver as well as of CAT activity and LPO in kidney. The results suggest that ozone injections combined with tested factors may provoke an oxidative stress. The effects of ozone therapy can not be explained as the results of ozone action on the antioxidative enzymes in rat.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 4","pages":"155-60"},"PeriodicalIF":0.0,"publicationDate":"1996-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20247806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A cerebrospinal fluid turnover in Parkinson's disease. 帕金森病的脑脊液循环。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-07-01
Z Jamrozik, L Królicki, H Kwieciński, M Florek
{"title":"A cerebrospinal fluid turnover in Parkinson's disease.","authors":"Z Jamrozik,&nbsp;L Królicki,&nbsp;H Kwieciński,&nbsp;M Florek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 30 patients with Parkinson's disease (PD) CT scan, isotopic cisternography and neuropsychological examination were performed to test possible relationship between cerebrospinal fluid (CSF) turnover, intellectual impairment and brain atrophy. Pathological cisternography was found in one third of the patients and it was positively correlated with the Columbia Rating Scale. Cerebral atrophy on CT was found more frequently in patients with earlier onset of PD. Combined pathological pattern on CT scan and on cisternography was correlated with intellectual decline. We conclude from this study, that in PD intellectual deterioration and brain atrophy separately are not connected with abnormal CSF turnover.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 3","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"1996-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20114935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analgesic effect of synthetic human calcitonin in patients with primary osteoporosis. 合成人降钙素对原发性骨质疏松患者的镇痛作用。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-07-01
P Kapuściński, M Tałałaj, J Borowicz, E Marcinowska-Suchowierska, R Brzozowski
{"title":"An analgesic effect of synthetic human calcitonin in patients with primary osteoporosis.","authors":"P Kapuściński,&nbsp;M Tałałaj,&nbsp;J Borowicz,&nbsp;E Marcinowska-Suchowierska,&nbsp;R Brzozowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Examinations were performed in 20 adult male and female patients (pts) suffering from acute back pain due to vertebral compression fracture secondary to osteoporosis proved by lateral X-rays of the dorso-lumbar spine (Th3-L5), and bone mineral density with the method of dual energy X-ray absorptiometry. The synthetic human calcitonin (SUC) (0.5 mg) was injected I.M. every day during 28 days. Analgesic effect was evaluated on 0, 3, 7, 14, 21 and 28th day by patient's assessment of functional capacity, and physician's assessment of pain and mobility. On the same days biochemical variables of Ca-P homeostasis were determined. Treatment with calcitonin resulted in a positive analgesic effect. The functional capacity and mobility of pts increased with diminution of pain. No significant alterations of Ca-P homeostasis was observed. Mild and transient side effects as nausea and tachycardia were negligible. SHC appears to have a significant analgesic effect in treatment of primary osteoporosis.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 3","pages":"83-6"},"PeriodicalIF":0.0,"publicationDate":"1996-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20114936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cesarean section in grandmultiparas. 剖宫产术。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-07-01
F A Ali, B Spiewankiewicz
{"title":"Cesarean section in grandmultiparas.","authors":"F A Ali,&nbsp;B Spiewankiewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Grandmultiparity which has been considered to be a factor in maternal and neonatal morbidity [3], is still high in Libya as compared with European countries. A retrospective study of one aspect of this problem concerned the Cesarean section in patients who had delivered 6 or more babies. During the period of January Ist to the end of December 1993, the records of all grandmultiparous women who delivered by a Cesarean section (287 cases) were reviewed at Obstetric Department of University Hospital in Benghazi-Libya. The incidence was 7.9%. The most common indications for the Cesarean section were: fetopelvic disproportion or failure to progress (26.5%), previous Cesarean sections (19.5%), malpresentation (16%), placenta praevia and failed induction for each of them (7%). The perinatal mortality was 17/1000. We conclude that grandmultiparas require Cesarean sections more frequently than nongrandmultiparas, especially primary and emergency Cesarean sections. For such patients an effective family planning program is necessary.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 3","pages":"87-91"},"PeriodicalIF":0.0,"publicationDate":"1996-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20114937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Doxazosin-alpha-1-adrenergic antagonists drug in the long-term (3 years). Management of benign prostatic hyperplasia. 长期(3年)服用多沙唑辛- α -1肾上腺素能拮抗剂。良性前列腺增生的处理。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1996-07-01
S Dutkiewicz
{"title":"Doxazosin-alpha-1-adrenergic antagonists drug in the long-term (3 years). Management of benign prostatic hyperplasia.","authors":"S Dutkiewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To evaluate the efficacy and tolerability of doxazosin in the long-term (3yr.) treatment of bladder outflow obstruction resulting from BPH. Data were obtained in 64 patients with BPH. The main outcome measures were urodynamic and symptomatic evaluation for efficacy. In the three year follow up study on doxazosin, including 33 patients remaining on the drug drug and 11 operated (total 44) and excluding those who abandoned the therapy or died, the positive effect of the treatment was found in 75 percent and failure in 25 percent of cases. Doxazosin was well-tolerated and produced both urodynamic and symptomatic improvement in men with BPH. Results from clinical trials demonstrate doxazosin is effective and safe and well tolerated in both normotensive and hypertensive patients with BPH.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"28 3","pages":"93-102"},"PeriodicalIF":0.0,"publicationDate":"1996-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20113662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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