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Resection of the liver in a metastatic disease caused by renal carcinoma. 肾癌引起的转移性疾病的肝脏切除术。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
A A Antoniewicz, M Krawczyk, J A Polański, A Borówka, A Borkowski
{"title":"Resection of the liver in a metastatic disease caused by renal carcinoma.","authors":"A A Antoniewicz,&nbsp;M Krawczyk,&nbsp;J A Polański,&nbsp;A Borówka,&nbsp;A Borkowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two patients are presented who had their livers resected because of the metastasis of the kidney tumour. It is a contribution in the discussion on the possibility of treatment of a well-advanced cancer disease. The treatment chosen was possible because of the close co-operation between two different teams of surgeons.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"143-4"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18672038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pregnant woman with Ebstein's anomaly. A case report. 一个患有Ebstein异常的孕妇。一份病例报告。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
F Gültekin, E Baskin, A Gökalp, K Dogan
{"title":"A pregnant woman with Ebstein's anomaly. A case report.","authors":"F Gültekin,&nbsp;E Baskin,&nbsp;A Gökalp,&nbsp;K Dogan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ebstein's anomaly is characterised by downward displacement of the tricuspid valve into the right ventricle. The most deformed leaflets are the septal and mural ones. The abnormally situated tricuspid orifice produces a portion of the right ventricle lying between the atrioventricular ring and the origin of the valve. This proximal segment is atrialized. Commonly associated anatomical defects include a atrial septal second defect, a ventricular septal defect, pulmonary stenosis or atresia, and mitral valve prolapse. An accessory conduction pathway (Wolf-Parkinson White syndrome) was found in this malformation. It is thought that this malformation is due to a direct teratogenic effect of lithium on the atrioventricular junction. Ebstein's anomaly can be accurately identified by echocardiography and angiography.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"149-51"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18670562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of quinolinic acid administered during pregnancy on the hippocampal formation of rat's offspring (ultrastructural investigation). 妊娠期间给予喹啉酸对大鼠后代海马形成的影响(超微结构观察)。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
M Beskid, Z Rózycka
{"title":"The effect of quinolinic acid administered during pregnancy on the hippocampal formation of rat's offspring (ultrastructural investigation).","authors":"M Beskid,&nbsp;Z Rózycka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pyramidal cells of CA1 hippocampal area of rat's offspring was ultrastructurally examined after quinolinic acid administration to mothers during the gestational period, in order to mimic the congenital metabolic disturbances resulting from an endogenous excess of quinolinic acid within foetal tissues. Hence, quinolinic acid was administered to mothers intraperitoneally in a dose of 60 mmol, once daily, throughout the entire gestation period. Brain specimens were taken on Day 5 after birth, from experimental and control animals. The only observed change within the pyramidal cells was swelling of both neuronal somata and dendrites, as well as a distinct swelling of astroglia cytoplasm and processes. Besides this, toxic effects, like edema signs, were observed. Neurons of the hippocampal formation were found to be particularly susceptible to quinolinic acid toxicity. The highly vulnerable neurons were located within the CA1-area. The neuronal vulnerability correlates remarkably well with those responding to the excitatory effects of quinolinic acid in electrophysiological experiments (Perkins and Stone 1983 a,b). This region was shown to be rich in NMDA receptors (Cotman et al. 1987; Greenamyre et al. 1984). The susceptibility of neuronal cell bodies of the hippocampal formation of an adult mammalian to the quinolinic acid toxicity, has been investigated with great interest (Schwarcz et al. 1984; Taraszewska et al. 1991; Kida and Matyja 1990; Speciale et al. 1987). Yet there is little information on the course of the foetal development. Hence, in our experiments, quinolinic acid was administered to the mother throughout the gestation period in order to mimic the congenital metabolic disturbances resulting from an excess of quinolinic acid within foetal tissues.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"133-8"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18672034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vestibular system in alcohol and drug addicts. 酒精和毒品成瘾者的前庭系统。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
M Józefowicz-Korczynska, M Lukomski, P Kurnatowski
{"title":"Vestibular system in alcohol and drug addicts.","authors":"M Józefowicz-Korczynska,&nbsp;M Lukomski,&nbsp;P Kurnatowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study was carried out on 223 alcoholics, 96 drug addicts and 50 healthy persons as a control group. Clinical otolaryngological examination, ENG examination, and audiometry diagnosis were made. The results showed lesions of the central part of the vestibular system in alcohol and drug addicts which are much more evident on ENG examination than in clinical otolaryngological findings. We have observed that trauma capitis does not cause increased vestibular disturbances in addicted persons. Audiologic findings indicate significant hearing loss in both groups.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"123-6"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18672032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human papillomavirus (HPV) infection in premalignancy and carcinoma of the penis. Clinical relevance. 人乳头瘤病毒(HPV)在阴茎癌前和癌中的感染。临床相关性。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
S Dutkiewicz, A Witeska
{"title":"Human papillomavirus (HPV) infection in premalignancy and carcinoma of the penis. Clinical relevance.","authors":"S Dutkiewicz,&nbsp;A Witeska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent progress in molecular biology suggests a certain relationship between the penile cancer and human papillomavirus infection. The relationship between carcinomas of the penis and cervix uteri is very important in married couples. Genital HPV infections manifest themselves as condylomas. Men who carry the virus must be identified and treated. The authors discuss the current therapy and present rare cases of penis carcinoma whose etiology is connected with HPV inflammation. The treatment of the inflammation with HPV should be least invasive.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"139-41"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18672037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetically determined sparteine oxidation and sulfadimidine acetylation polymorphism in patients with non-occupational urinary bladder cancer. 非职业性膀胱癌患者斯巴达胺氧化和磺胺嘧啶乙酰化多态性的基因测定
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
K Orzechowska-Juzwenko, P Niewiński, J Pawlik, P Milejski, J Dembowski, L Swiebodzki, J Lorenz
{"title":"Genetically determined sparteine oxidation and sulfadimidine acetylation polymorphism in patients with non-occupational urinary bladder cancer.","authors":"K Orzechowska-Juzwenko,&nbsp;P Niewiński,&nbsp;J Pawlik,&nbsp;P Milejski,&nbsp;J Dembowski,&nbsp;L Swiebodzki,&nbsp;J Lorenz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of our study revealed a predominance of the percentage of extensive metabolizers (EM) of sparteine (94.8%) among 58 patients with non-occupational urinary bladder cancer in comparison with the percentage of extensive metabolizers (91.2%) in healthy persons; the difference being not statistically significant. However, among ultrarapid (EM) oxidators with the metabolic ratio (MR) < 0.5 the difference in the MR frequency distribution between 15 patients with bladder cancer (25.9%) and 18 healthy persons (11.25%) was statistically significant. Therefore, our studies provide some evidence of a possible relationship between the EM sparteine oxidation phenotype and the susceptibility to non-occupational bladder cancer. Not statistically significant slight prevalence of the percentage of slow acetylators (SA) (53.1%) among 32 urinary bladder cancer patients in comparison with the percentage of SA (49%) among 45 healthy persons may confirm the conclusion that a slow acetylator phenotype is not associated with the increased risk of the development of non-occupational urinary bladder cancer.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"145-8"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18670560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropeptide Y and alpha-adrenoceptor interactions in patients with essential hypertension. 神经肽Y与肾上腺素受体在原发性高血压患者中的相互作用。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-10-01
B Wocial, H Ignatowska-Switalska, P Pruszczyk, Z Zukowska-Grójec, W Januszewicz
{"title":"Neuropeptide Y and alpha-adrenoceptor interactions in patients with essential hypertension.","authors":"B Wocial,&nbsp;H Ignatowska-Switalska,&nbsp;P Pruszczyk,&nbsp;Z Zukowska-Grójec,&nbsp;W Januszewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neuropeptide Y (NPY) is a vasoconstrictor sympathetic cotransmitter and a modulator of adrenergic function whose role in hypertension is yet unknown. We studied the co-release of NPY and noradrenaline (NA) in patients with essential hypertension (13 females, 11 males, age 42 +/- 13 years) by measuring plasma levels of NPY-immunoreactivity (-ir, radioimmunoassay) and NA (radioenzymatic method) following administration of clonidine (CL 300 micrograms, p.o.). At rest, only NPY-ir levels significantly correlated with diastolic blood pressure (DBP, r = 0.42, p < 0.05). Three hours after CL, there were a decrease in mean arterial pressure and plasma NA (by 31 +/- 14 mmHG, p < 0.05 and 92 +/- 10 pg/ml, p < 0.01) but no change in NPY-ir levels. Patients were subsequently subdivided into groups with high (> or = 90 mmHg) or normal DBP (< or = 89 mmHg) and with or without elevated plasma NA levels (above or below 414 pg/ml, a normotensive mean +1 standard deviation). In hypertensives, but not in those with normal DBP, plasma NPY-ir correlated not only with DBP but also with systolic and mean blood pressure (r = 0.53 and r = 0.60, respectively) at rest. Hypertensives with \"high\" NA had significantly lower resting plasma NPY-ir levels than those with \"low\" NA (7.1 +/- 3.6 vs 14.7 +/- 6.0 fmol/ml, p < 0.05). In the former group, CL evoked the greatest fall in plasma NA, and also decreased NPY-ir levels by 50% (p < 0.05). Thus, patients with essential hypertension were found to display differential patterns of changes in sympathetic cotransmitters to clonidine. NPY may contribute to the increased blood pressure in hypertensives and together with NA, mediate hypotensive action of clonidine but only in the hyperadrenergic subgroup of hypertensives.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 4","pages":"127-31"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18672033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular analysis of alleles segregation at RFLPs within RB-1 gene in four families with hereditary retinoblastoma. 4个遗传性视网膜母细胞瘤家族RB-1基因RFLPs等位基因分离的分子分析。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-07-01
E Kostyk, J Wieckiewicz, A Sutkowska, H Zygulska-Mach, J J Pietrzyk
{"title":"Molecular analysis of alleles segregation at RFLPs within RB-1 gene in four families with hereditary retinoblastoma.","authors":"E Kostyk,&nbsp;J Wieckiewicz,&nbsp;A Sutkowska,&nbsp;H Zygulska-Mach,&nbsp;J J Pietrzyk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Four families with suspected hereditary retinoblastoma in proband and one other family member were examined by genetic segregation analysis of the RB-1 gene loci with specific RFLPs of chromosome 13. Two families, TA-6 and partially CK-46, were informative using this method. In TA-6 family healthy sister (TA-6/10) of the proband was shown not to be a carrier of the mutant RB-1 gene. These results show that the segregation analysis of RB-1 gene loci with specific RFLPs, used as the DNA markers, could be helpful in the genetic diagnosis and counselling in families with hereditary retinoblastoma.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 3","pages":"105-8"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18607681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The "H-graft" in portacaval shunt in dogs. 狗门静脉分流中的“h -移植物”。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-07-01
A Grga, Z Maticić, D Hlevnjak, B Hofman
{"title":"The \"H-graft\" in portacaval shunt in dogs.","authors":"A Grga,&nbsp;Z Maticić,&nbsp;D Hlevnjak,&nbsp;B Hofman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>When working experimentally on dogs we have investigated the possibility of using an autogenous vein graft and polytetrafluoroethylene (Gore-Tex) prosthesis in the construction of the portacaval shunt. The portacaval shunt flow has been examined under similar hemodynamic conditions by experimenting on surviving dogs with the internal jugular vein and the above prosthesis. This study presents methods of research, hemodynamic measurements and the technique of portacaval shunt construction. After performance of the arteriovenous mesenteric-renal fistula we have succeeded in raising partially the portal vein pressure with the increase in the venous blood flow markedly higher. The portacaval shunt flow and the mesenteric-renal fistula have been verified by aortography and on autopsy. The jugular vein employed in the construction of the portacaval shunt remained unobstructed in 6 dogs (75 per cent) and the Gore-Tex prosthesis in 4 (50 per cent).</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 3","pages":"109-12"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18607682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin metastasis of bladder carcinoma. A case report. 膀胱癌的皮肤转移。一份病例报告。
Materia medica Polona. Polish journal of medicine and pharmacy Pub Date : 1994-07-01
T A Serel, G Ozdemir, L S Yaman, H Ozdemir
{"title":"Skin metastasis of bladder carcinoma. A case report.","authors":"T A Serel,&nbsp;G Ozdemir,&nbsp;L S Yaman,&nbsp;H Ozdemir","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of not commonly encountered metastasis of bladder cancer to skin has been studied. The usual sites of the bladder cancer metastasis are lymph nodes, liver, lung and bone.</p>","PeriodicalId":76124,"journal":{"name":"Materia medica Polona. Polish journal of medicine and pharmacy","volume":"26 3","pages":"113-4"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18608267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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