{"title":"ACAC (albumin-collodion coated activated charcoal) hemoperfusion: in-vitro removal and clearance of theophylline.","authors":"E Espinosa-Meléndez, T M Chang","doi":"10.3109/08860228009065324","DOIUrl":"https://doi.org/10.3109/08860228009065324","url":null,"abstract":"<p><p>This study was designed to evaluate the effectiveness of ACAC charcoal to remove theophylline. Activated charcoal prepared according to Chang's technique was used in in vitro batch and clearance experiments. Theophylline was removed with a T1/2 of less than 5 minutes in the stirred batch experiments. The clearance studies showed values of 102, 145, and 208 ml/min (extrapolated to 300 g of ACAC charcoal), for extrapolated flow rates of 120, 240, and 360 ml/min. The ACAC charcoal is very efficient in removing theophylline in vitro from an aqueous solution. The efficiency of ACAC hemoperfusion for the treatment of severe, acute theophylline intoxication has also been demonstrated here.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 1","pages":"21-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065324","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18420760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Shin, M Matsuo, S Shinko, Y Fujita, S Inoue, R Sakai, M Nishioka
{"title":"A study on hemodialysis leukopenia using various dialyzers.","authors":"J Shin, M Matsuo, S Shinko, Y Fujita, S Inoue, R Sakai, M Nishioka","doi":"10.3109/08860228009065327","DOIUrl":"https://doi.org/10.3109/08860228009065327","url":null,"abstract":"<p><p>Hemodialysis leukopenia was studied using various dialyzers and membranes. We found that dialyzers with cellulosic membranes caused marked leukopenia, but in recently developed non cellulosic membranes, its occurrence was significantly less. Additionally, our results showed a newly developed cellulose acetate membrane to correlate well with the non cellulose membranes regarding leukopenia, in spite of it being a derivative of cellulose. The extent of white blood cell decrease seemed to correlate inversely with an increase in the ultrafiltration rate per membrane area of dialyzer. The relationship between leukopenia and hypoxemia was examined also. The results of this investigation are included, however, we feel that more research is necessary before any conclusions can be made.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 1","pages":"51-62"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065327","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18420763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Popli, T S Ing, J T Daugirdas, G S Stroka, E O Osanloo, R M Vilbar, R Pifarre, W P Geis
{"title":"Treatment of uremic pericardial effusion by local steroid instillation via subxiphoid pericardiotomy.","authors":"S Popli, T S Ing, J T Daugirdas, G S Stroka, E O Osanloo, R M Vilbar, R Pifarre, W P Geis","doi":"10.3109/08860228009065330","DOIUrl":"https://doi.org/10.3109/08860228009065330","url":null,"abstract":"<p><p>Seven maintenance hemodialysis patients suffering from intractable uremic pericardial effusion were treated with instillation of a non-absorbable steroid, triamcinolone hexacetonide, into the pericardial sac via a large-bore catheter. The latter was placed under direct vision by subxiphoid pericardiotomy. All patients responded to the treatment while complications of the procedure were few and minor.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 2-3","pages":"83-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065330","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18451574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Aspergillus and Candida precipitins in renal dialysis and transplant patients.","authors":"H S Novey, I D Wells, N D Vaziri","doi":"10.3109/08860227909063952","DOIUrl":"https://doi.org/10.3109/08860227909063952","url":null,"abstract":"<p><p>Serum precipitin tests to Aspergillus and Candida antigens were used to define the rate of infectivity with these fungal organisms in patients on renal dialysis and after kidney transplantation. A total of 58 studies in 53 consecutive patients, of whom 41.5% were post-transplant an average of 14.6 months, failed to detect significantly more precipitin activity than in a normal population. The specificity of this non-immunoreactivity was supported by the absence of clinical or post-mortem evidence of fungal invasion. Since serum precipitins develop despite immunosuppressive therapy, and cases of fungal invasion in transplant recipients may occur sporadically in clusters, monitoring of renal transplant patients with these relatively simple tests should detect endemic occurrences of aspergillosis and candidiasis.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 4","pages":"349-60"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909063952","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemoperfusion: present and future.","authors":"M C Gelfand","doi":"10.3109/08860227909064908","DOIUrl":"https://doi.org/10.3109/08860227909064908","url":null,"abstract":"","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909064908","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11675086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemodialysis for methanol intoxication.","authors":"M Tobin, E Lianos","doi":"10.3109/08860227909064915","DOIUrl":"https://doi.org/10.3109/08860227909064915","url":null,"abstract":"<p><p>A patient with toxic levels of methanol was hemodialyzed while receiving an ethanol infusion. It was demonstrated that during the dialysis significant quantities of both ethanol (17.70 gms) and methanol (26.69 gms) were extracted. Also, it was shown that the ethanol did not competetively inhibit the extraction of the methanol. Since ethanol is removed in significant quantities during dialysis, one should increase its infusion rate during hemodialysis and decrease the rate when the patient is not being dialyzed. This would achieve adequate and constant blood levels of ethanol and would satisfactorily inhibit the metabolism of methanol by the liver.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 1","pages":"97-106"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909064915","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11675091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The treatment of severe drug intoxication with charcoal hemoperfusion in series with hemodialysis.","authors":"C Bentley, C M Kjellstrand","doi":"10.3109/08860227909063951","DOIUrl":"https://doi.org/10.3109/08860227909063951","url":null,"abstract":"<p><p>Two patients were treated for serious phenobarbital intoxication with charcoal perfusion and hemodialysis in series. Both patients experienced decreases in coma, but both of them bled after treatment. Phenobarbital levels were decreased to 50% with treatments, and there was not any significant difference of the clearance for the two devices.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 4","pages":"337-48"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909063951","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11478291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L J Dziukas, S M Douglas, P M Carter, D C Campbell, J T Andrews, A J d'Apice, P Kincaid-Smith
{"title":"Evaluation of the Gambro Lundia Major 1.36 m2 disposable parallel plate dialyzer.","authors":"L J Dziukas, S M Douglas, P M Carter, D C Campbell, J T Andrews, A J d'Apice, P Kincaid-Smith","doi":"10.3109/08860227909063948","DOIUrl":"https://doi.org/10.3109/08860227909063948","url":null,"abstract":"<p><p>The Gambro Lundia Major 1.36 m2 dialyzer was assessed in vivo in ten hemodialysis patients. Urea and creatinine clearances (measured as whole blood values at 60 minutes with a blood flow rate of 200 ml/minute) were 166 +/- 8 m/minute (mean +/- standard error of the mean, n = 9) and 115 +/- 4 ml/minute (n = 11). The creatinine clearance is 15% lower than in vitro data. There was a marked decrease in urea and creatinine clearance with third use of the dialyzer. The ultrafiltration rate was 490 ml/hour/100 mmHg. The priming volume was 125 ml (at a transmembrane pressure of 100 mmHg) and residual blood volume in the dialyzer was 0.57 +/- 0.11 ml (n = 5). The handling, storage and ease of disposal of the dialyzer is better than previous models and its performance characteristics are clinically acceptable.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 4","pages":"309-25"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909063948","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11478433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V E Andreucci, V Calderaro, B Memoli, V Terracciano
{"title":"A new semiautomated apparatus for hemofiltration.","authors":"V E Andreucci, V Calderaro, B Memoli, V Terracciano","doi":"10.3109/08860227909063938","DOIUrl":"https://doi.org/10.3109/08860227909063938","url":null,"abstract":"<p><p>A new semiautomated apparatus for hemofiltration has been described. It is a postdilutional hemofiltration system that utilizes the RP-610 dialyzer and is made of standard lines used for hemodialysis, a blood pump and two precise volumetric pumps, Logeais-TEC model, for the ultrafiltrate and for the substitution fluid. The ultrafiltrate compartment of the hemofilter is connected to a manometer for detecting positive or negative pressure. The transmembrane pressure TmP is given only by the pressure on the blood side that is regulated by the screw clamp in the venous line. Once started the whole system may be regulated by this screw clamp in order to maintain zero pressure in the ultrafiltrate compartment, provided that ultrafiltration rate does not exceed 65 ml/min. This system is sufficiently accurate to replace bed scales or any other gravimetric device.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 2-3","pages":"165-71"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909063938","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11716259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relative performance test of hollow fiber dialyzers.","authors":"H Naito, M Shimizu, M Higashi","doi":"10.3109/08860227909063939","DOIUrl":"https://doi.org/10.3109/08860227909063939","url":null,"abstract":"<p><p>While a number of different hollow fiber dialyzers are on the market today, the present author studied three of the cellulosic membrane dialyzers, SD-1, CF-1500 and K-102, as to their dialysance, solutes removal rate, UFR and blood residue characteristics. In order to compare these characteristics due to the difference of the membrane and the structural geometry of the dialyzers, the test results were analysed by means of analyses of variance.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"3 2-3","pages":"173-90"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227909063939","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11716260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}