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Vancomycin therapy for serious staphylococcal infections in chronic hemodialysis patients. 万古霉素治疗慢性血液透析患者严重葡萄球菌感染。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065341
M H Bierman, C A Needham-Walker, M Hammeke, J D Egan
{"title":"Vancomycin therapy for serious staphylococcal infections in chronic hemodialysis patients.","authors":"M H Bierman,&nbsp;C A Needham-Walker,&nbsp;M Hammeke,&nbsp;J D Egan","doi":"10.3109/08860228009065341","DOIUrl":"https://doi.org/10.3109/08860228009065341","url":null,"abstract":"<p><p>Vancomycin therapy during 7 episodes of serious staphylococcal infections in chronic hemodialysis patients was monitored by a sensitive bioassay technique. One gm of vancomycin was given during dialysis at a mean dosage interval of 7 days for a mean duration of 48 days. Serum peak and trough vancomycin levels were monitored during therapy. Accumulation of vancomycin occurred in 1 patient on prolonged therapy; progressive rising through levels required a reduction in vancomycin dosage. Pre and post-dialysis vancomycin levels in one patient were unchanged. Vancomycin was effective in eradication of all staphylococcal infections and bacteremias. Three A-V shunt infections required surgical revision; 2 A-V fistula infections were salvaged with vancomycin therapy alone. We conclude that 1 gm vancomycin every 7 days is an effective regimen for serious staphylococcal infections in chronic hemodialysis patients. Monitoring of vancomycin levels insures maintenance of adequate levels and prevents toxic accumulation.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 4","pages":"179-84"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065341","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18218567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Intraperitoneal infusion of non-absorbable steroids in the treatment of ascites and sterile peritonitis. 腹腔注射不可吸收类固醇治疗腹水和无菌性腹膜炎。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065326
J A Diaz-Buxo, J T Chandler, C D Farmer, P J Walker
{"title":"Intraperitoneal infusion of non-absorbable steroids in the treatment of ascites and sterile peritonitis.","authors":"J A Diaz-Buxo,&nbsp;J T Chandler,&nbsp;C D Farmer,&nbsp;P J Walker","doi":"10.3109/08860228009065326","DOIUrl":"https://doi.org/10.3109/08860228009065326","url":null,"abstract":"<p><p>The experience with intraperitoneal infusion of non-absorbable steroids (triamcinolon hexacetonide) in the treatment of intractable hemodialysis-associated ascites and severe sterile peritonitis is presented. All patients uniformly responded to therapy with prolonged periods of remission and no significant complications. We conclude that intraperitoneal steroidal administration offers an effective modality of therapy in the treatment of these complications.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 1","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065326","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18420762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Vascular responsiveness and body fluid status in patients on chronic hemodialysis. 慢性血液透析患者的血管反应性和体液状态。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065340
M Tajiri, Y Aizawa, S Sakai, K Imai, Y Hirasawa
{"title":"Vascular responsiveness and body fluid status in patients on chronic hemodialysis.","authors":"M Tajiri,&nbsp;Y Aizawa,&nbsp;S Sakai,&nbsp;K Imai,&nbsp;Y Hirasawa","doi":"10.3109/08860228009065340","DOIUrl":"https://doi.org/10.3109/08860228009065340","url":null,"abstract":"<p><p>The vascular responsiveness and the body fluid distribution were studied in 5 hypotensive and 11 normotensive patients on long-term hemodialysis. A diminished vascular responsiveness to intravenously infused norepinephrine or angiotensin II was found in uremic patients, especially in the hypotensive group. A slightly larger, but non-significant circulating blood volume (CBV) and a less extracellular fluid volume (ECF) was found in the hypotensive group as compared with those of the normotensive group. These results suggest that with autonomic nervous dysfunction, such a diminution of vascular responsiveness may be an another factor responsible for the development of hypotension.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 4","pages":"167-77"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065340","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18218566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Hemodialysis studies of antidiuretic hormone. 抗利尿激素的血液透析研究。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065342
N D Vaziri, R Skowsky, J Saiki, A Warner
{"title":"Hemodialysis studies of antidiuretic hormone.","authors":"N D Vaziri,&nbsp;R Skowsky,&nbsp;J Saiki,&nbsp;A Warner","doi":"10.3109/08860228009065342","DOIUrl":"https://doi.org/10.3109/08860228009065342","url":null,"abstract":"<p><p>Hemodialyzability of antidiuretic hormone (ADH) was studied in 14 patients undergoing hemodialysis procedure. In addition hemofiltration (dry dialysis) was performed in 8 patients and hemofiltrate samples were collected for ADH assay. The mean values for plasma ADH level in ingoing and outgoing blood were nearly identical. Moreover, no ADH was detectable in the hemofiltrate samples. These findings suggest lack of significant ADH removal by dialysis or hemofiltration.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 4","pages":"185-90"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18218568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Acute flank pain in dialysed patients. Demonstration of hydronephrosis by computer tomography. 透析患者的急性侧腹疼痛。计算机断层扫描显示肾积水。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065333
J Bommer, E Ritz, G van Kaick
{"title":"Acute flank pain in dialysed patients. Demonstration of hydronephrosis by computer tomography.","authors":"J Bommer,&nbsp;E Ritz,&nbsp;G van Kaick","doi":"10.3109/08860228009065333","DOIUrl":"https://doi.org/10.3109/08860228009065333","url":null,"abstract":"<p><p>Repeated episodes of acute renal flank pain were observed in a uremic patient on maintenance hemodialysis. Computer tomography during the acute attack repeatedly showed unilateral hydronephrosis which always subsided after passage of stones. X-ray failed to visualize the non-radioopaque stones and sonography was non-contributory. The stones consisted of organic matrix and contained protein material. The present observation documents that computer tomography is valuable in establishing the diagnosis of acute ureteral obstruction resulting from non-radioopaque renal stones in dialysed patients with contracted kidneys.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 2-3","pages":"109-14"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18451570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Peritoneal dialysis in the treatment of severe hypercalcemia. 腹膜透析治疗重度高钙血症。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065336
J W Hamilton, M Lasrich, P Hirszel
{"title":"Peritoneal dialysis in the treatment of severe hypercalcemia.","authors":"J W Hamilton,&nbsp;M Lasrich,&nbsp;P Hirszel","doi":"10.3109/08860228009065336","DOIUrl":"https://doi.org/10.3109/08860228009065336","url":null,"abstract":"<p><p>A 56-year-old man with multiple myeloma and compromised renal function underwent peritoneal dialysis for the treatment of severe hypercalcemia. During dialysis, peritoneal clearances of total calcium, unbound calcium, urea, and creatinine were assessed. Clearances of total calcium (4.8 +/- 0.4 ml/min) and unbound calcium (7.8 +/- 0.5 ml/min) were shown to vary directly with the clearances of urea (15.5 +/- 1.3 ml/min) and creatinine (8.5 +/- 0.8 ml/min). Despite relatively low clearances of all these solutes, during the period of 42 hours, 1,638 mg of calcium was removed in the dialysate and total serum calcium decreased from 17.6 mg/dl to 10.2 mg/dl. Our data indicates that peritoneal dialysis is an effective adjunct in controlling severe hypercalcemia and should be considered when other forms of therapy are inadequate.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 2-3","pages":"129-38"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065336","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18451572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Dialysis pruritus: effect of cimetidine. 透析性瘙痒:西咪替丁的作用。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065337
J Aubia, J Aguilera, I LLorach, C Garcia, E Rius, J LLoveras, J Masramon, M LLorach
{"title":"Dialysis pruritus: effect of cimetidine.","authors":"J Aubia,&nbsp;J Aguilera,&nbsp;I LLorach,&nbsp;C Garcia,&nbsp;E Rius,&nbsp;J LLoveras,&nbsp;J Masramon,&nbsp;M LLorach","doi":"10.3109/08860228009065337","DOIUrl":"https://doi.org/10.3109/08860228009065337","url":null,"abstract":"<p><p>The effect of oral Cimetidine compared to a classic antihistaminic and to a placebo was evaluated, under the double hypothesis of its anti-PTH and anti-pruritus action, in a population of patients recently included in Hemodialysis that were asked about the incidence and intensity of pruritus according to a scored questionnaire made for this purpose. No different efficacy of Cimetidine versus the antihistaminic classic and the placebo was observed in our study.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 4","pages":"141-5"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065337","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18218563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Sequential intraperitoneal administration of nitroprusside in patients maintained on peritoneal dialysis. 维持腹膜透析的病人按序腹腔注射硝普塞。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065344
E Riambau, J Lloveras, J Aubía, J Masramón, C García, M A Orfila, M Llorach
{"title":"Sequential intraperitoneal administration of nitroprusside in patients maintained on peritoneal dialysis.","authors":"E Riambau,&nbsp;J Lloveras,&nbsp;J Aubía,&nbsp;J Masramón,&nbsp;C García,&nbsp;M A Orfila,&nbsp;M Llorach","doi":"10.3109/08860228009065344","DOIUrl":"https://doi.org/10.3109/08860228009065344","url":null,"abstract":"<p><p>Clinical studies were made in order to determine the effects of intraperitoneal nitroprusside on the peritoneal clearances according to different frequencies of drug administration. An important increase of urea and creatinine clearances with 3.75 mg of nitroprusside per liter of dialysis solution was observed. The maximum effects were observed after four consecutive exchanges with the drug; its effects were maintained all through the peritoneal dialysis session and in some cases increased when alternative series of four exchanges with and without drug were carried on. The significative higher increase of the big solutes clearances suggests a vasodilator action of nitroprusside which should be also reflected on an increase of the middle size molecules clearances. Clinical tolerance was excellent and the blood pressure variations were negligible.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 4","pages":"203-17"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065344","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18218570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
The effect of hemodialysis on levels of cyclic nucleotide-associated hormones in patients with chronic renal failure. 血液透析对慢性肾功能衰竭患者环核苷酸相关激素水平的影响。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065335
C M Maillet, A J Garber
{"title":"The effect of hemodialysis on levels of cyclic nucleotide-associated hormones in patients with chronic renal failure.","authors":"C M Maillet,&nbsp;A J Garber","doi":"10.3109/08860228009065335","DOIUrl":"https://doi.org/10.3109/08860228009065335","url":null,"abstract":"<p><p>In order to determine the molecular basis for the loss of catecholamine responsiveness in skeletal muscle in chronic azotemia, plasma and serum levels of catecholamines and other hormones whose mechanisms of action are associated in part with cyclic nucleotide mediation were assessed in 37 patients with chronic azotemia. Samples were obtained prior to and immediately following conventional hemodialysis. Plasma epinephrine and norepinephrine levels in patients predialysis were increased 50% and 25% respectively compared to control subjects. Levels of insulin, prolactin, aldosterone and renin were also in creased in azotemic patients prior to dialysis. Conventional hemodialysis reduced serum levels of growth hormone, but had no effect of the elevated levels of all other hormones found in patients predialysis. In particular, plasma epinephrine and norepinephrine levels were unaffected by hemodialysis. Despite these findings, hemodialysis did reduce to normal levels the elevated plasma levels of cyclic AMP and cyclic GMP observed in uremic subjects predialysis. These data are consistent with increased adrenergic outflow in patients with chronic azotemia, and suggest a mechanism of homologous desensitization of the catecholamine receptor adenylyl cyclase unit in chronic azotemia.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 2-3","pages":"121-8"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065335","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17317421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Antidiuretic hormone in end-stage renal disease. 终末期肾病的抗利尿激素。
Journal of dialysis Pub Date : 1980-01-01 DOI: 10.3109/08860228009065329
N D Vaziri, R Skowsky, J Saiki
{"title":"Antidiuretic hormone in end-stage renal disease.","authors":"N D Vaziri,&nbsp;R Skowsky,&nbsp;J Saiki","doi":"10.3109/08860228009065329","DOIUrl":"https://doi.org/10.3109/08860228009065329","url":null,"abstract":"<p><p>Quantative data on plasma levels of antidiuretic hormone (ADH) in renal failure are limited. We measured predialysis plasma ADH levels using a double antibody radioimmunoassay in 14 patients with end-stage renal failure. Plasma ADH was inappropriately elevated in the majority of tested patients despite normal plasma osmolality, moderately elevated blood pressure, and hypervolemia. The etiology of increased plasma ADH in our population is unclear.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"4 2-3","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228009065329","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18451573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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