N G De Santo, D Cirillo, R Senatore, T Cicchetti, M Manzo, G Capasso, C Giordano
{"title":"Comparing schedules of daily peritoneal dialysis.","authors":"N G De Santo, D Cirillo, R Senatore, T Cicchetti, M Manzo, G Capasso, C Giordano","doi":"10.3109/08860227809079319","DOIUrl":"https://doi.org/10.3109/08860227809079319","url":null,"abstract":"Starting November 1973, peritoneal dialyses have been performed 7 days a week on a group of 18 patients, 11 of whom still on the program. A short daily dialysis technique at a dialysate flow of 2.5 L/hour was used. This group of patients has undergone 9,724 dialyses, 86.8% of which at home.A group of 4 patients had to be switched to hemodialysis. During the last 16 months a total of 5,670 short daily dialyses have been performed, 97.4% of which at home.Another group of 6 patients has undergone Continuous Ambulatory Peritoneal Dialysis (CAPD) for 24 hours daily with 10-liter dialysate containing 3-4.25 g/100 ml dextrose. A total of 967 dialyses have been performed. Peritonitis occurred in 7 instances, and 2 patients had to be switched to hemodialysis.In summary, daily dialysis with either schedule reveals itself suitable for home program and requires a much smaller financial effort from the community. The data presented indicate that CAPD constitutes the most physiological approach to the problem of waste ...","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 4","pages":"311-24"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809079319","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11922289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V K Bansal, S Popli, T S Ing, J E Hano, W P Geis, M R Kamadana
{"title":"Intraperitoneal infusion of a nonabsorbable steroid in hemodialysis-associated ascites.","authors":"V K Bansal, S Popli, T S Ing, J E Hano, W P Geis, M R Kamadana","doi":"10.3109/08860227809079323","DOIUrl":"https://doi.org/10.3109/08860227809079323","url":null,"abstract":"<p><p>Ascites occurring in long-term hemodialysis patients continues to be a difficult management problem. Several modalities have been employed with varying success. Because of the similarities between uremic pericardial effusion and hemodialysis-associated ascites, infusion of the nonabsorbable steroid, triamcinolone hexacetonide, was attempted in five patients with the latter ailment which had become intractable. None of the patients responded and in two there were adverse effects. We conclude that for the management of this variety of ascites, intraperitoneal administration of a nonabsorbable steroid is ineffective and may be accompanied by undesirable reactions.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 4","pages":"379-85"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809079323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11922293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J R Shideman, R M Meyer, A J Streifel, R E Lynch, S M Mauer, C M Kjellstrand
{"title":"The evaluation and applications of hemodialyzers for pediatric patients.","authors":"J R Shideman, R M Meyer, A J Streifel, R E Lynch, S M Mauer, C M Kjellstrand","doi":"10.3109/08860227809080088","DOIUrl":"https://doi.org/10.3109/08860227809080088","url":null,"abstract":"<p><p>It is difficult to determine which pediatric hemodialyzer to use in a given clinical situation since there is no comprehensive comparison of pediatric hemodialyzers. We evaluated five currently available disposable pediatric hemodialyzers in vitro and in vivo during treatment of pediatric patients. Two dialyzers, Gambro Mini-Minor and Viva Cell 0.2 are well suited to small pediatric patients weighing less than 10 kg. Three of the dialyzers are well suited to the pediatric patients weighing greater than 10 kg (Gambro Minor, Cordis Dow 0.6, Viva Cell 0.5). By considering the clinical status of the child and the performance characteristics of the dialyzer (solute removal, priming volume, ultrafiltration, etc.) it is possible to employ a hemodialyzer which more precisely meets the needs of the child without increasing risk factors associated with pediatric hemodialysis.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 3","pages":"217-33"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11922376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kinetics of infused acetate and effect on plasma pyruvate and lipid concentrations in uremic and non-uremic dogs.","authors":"R J Morin, L S Guo, S J Rorke, W D Davidson","doi":"10.3109/08860227709082389","DOIUrl":"https://doi.org/10.3109/08860227709082389","url":null,"abstract":"<p><p>During acetate infusion at a rate of 10 millimoles/kg/hr arterial blood acetate levels rose progressively to maximums of 7.9 +/- 1.7 mM in uremic dogs and 10.8 +/- 1.4 mM in non-uremic dogs. Following cessation of infusion, removal of acetate followed first order kinetics. Acute uremia had no significant effect on mean clearance rates of acetate (1.28 +/- 0.28 L/kg/hr uremics vs 0.92 +/- 0.22 in non-uremics) or upon blood half-life of acetate following infusion (9.7 min. vs 10.9 min.). Plasma pyruvate levels rose during infusion from 1.5 to 4.4 mg/dl in the uremic dogs and following infusion rose further to 6.5 mg/dl. In the non-uremic dogs pyruvate was not significantly elevated until 30 min. post-infusion. Plasma free fatty acids increased from 79 to 131 mumoles/dl during acetate infusion in the uremic dogs, but did not change significantly in the non-uremic group. Plasma cholesterol and triglycerides increased after induction of uremia, but showed no significant changes as a result of acetate infusion in either group. These results suggest that the electrolyte and lipid abnormalities that occur in hemodialyzed uremic patients may be related to the acetate load these patients receive during dialysis.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 8","pages":"763-80"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709082389","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11811700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The treatment of chronic renal failure by transplantation.","authors":"N L Tilney, A Chang","doi":"10.3109/08860227709038428","DOIUrl":"https://doi.org/10.3109/08860227709038428","url":null,"abstract":"<p><p>The entire transplantation experience at the Peter Bent Brigham Hospital has been reviewed. This extends between 1951 and 1976, a 25 year period. Information on all patients has been undated through September 1976. Four different periods in the total experience have been compared, as determined by variations in immunosuppressive protocols. Although survival of renal allografts have plateaued over the past several years, the progressive decline in recipient mortality makes renal transplantation an increasingly attractive alternative to dialysis. Transplantation should be used in close conjunction with dialysis in the long-term treatment of patients with chronic renal failure.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 4","pages":"379-95"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709038428","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11555927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Matthaei, P Kramer, C Langescheid, C McIntosh, G Schwinn, R Ebert, R Arnold, G Schauder, F Scheler
{"title":"Elimination of hormones through hemofiltration.","authors":"D Matthaei, P Kramer, C Langescheid, C McIntosh, G Schwinn, R Ebert, R Arnold, G Schauder, F Scheler","doi":"10.3109/08860227709037659","DOIUrl":"https://doi.org/10.3109/08860227709037659","url":null,"abstract":"<p><p>The concentrations of testosterone, cortisone, gastrin, GIP, somatomedin B, insulin, HGH, and TSH have been determined in the plasma and the ultrafiltrate of five uremic patients undergoing intermittent hemofiltration treatment. There was a considerable loss of gastrin, GIP, somatomedin B, and insulin by hemofiltration treatment; the plasma concentrations, however, did not decrease. Cortisone, HGH, and TSH were not detectable in the ultrafiltrate. Our results therefore indicate that hemofiltration does not cause a hormone deficiency syndrome. On the contrary, the loss of degradation products of hormones with disturbing biological activity may be a favourable effect of the hemofiltration treatment.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 6","pages":"641-9"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709037659","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11811844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Capillary membranes for hemofiltration.","authors":"U V Mylius, E Streicher, H W Schneider","doi":"10.3109/08860227709037667","DOIUrl":"https://doi.org/10.3109/08860227709037667","url":null,"abstract":"Membranes for hemofiltration were manufactured from blood-compatible polyamides in the form of capillaries. Hemofiltration units containing these capillaries were tested in vitro with aqueous solutions of salts and metabolites and with whole human blood. The results show that the capillary membranes fulfill the requirements for a membrane suitable for hemofiltration.","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 7","pages":"715-26"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709037667","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11811851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Köstering, J Girndt, D Matthaei, R Naidu, E Quellhorst
{"title":"Alterations of clotting factors and platelets during hemofiltration.","authors":"H Köstering, J Girndt, D Matthaei, R Naidu, E Quellhorst","doi":"10.3109/08860227709037656","DOIUrl":"https://doi.org/10.3109/08860227709037656","url":null,"abstract":"<p><p>The influence of hemofiltration on the number of platelets and on coagulation factors was investigated in patients with chronic renal insufficiency. These investigations were done on 12 patients during 22 treatments with hemofiltration. Blood samples were taken before hemofiltration, 10, 30 and 120 minutes after the beginning of the treatment and at the end of hemofiltration. In comparison to the original values we found a loss of platelets, a small decrease in the concentration of fibrinogen and a small increase in the fibrin monomer complex, plasminogen, antithrombin III, alpha1-antitrypsin and in alpha2-macroglobulin. The thrombin time, the partial thromboplastin time and Quick's test showed that the blood of these patients contained sufficient hepatin. Use of fibrin plates (Astrup) showed no signs of fibrinolytic activity. Compared to the results, which were obtained some years ago during hemodialysis, we found a smaller extent of alterations of blood coagulation factors and number of platelets.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 6","pages":"607-17"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709037656","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11297366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Asymmetric polyamide hollow-fiber filters in the hemofiltration system.","authors":"E Streicher, H Schneider","doi":"10.3109/08860227709037668","DOIUrl":"https://doi.org/10.3109/08860227709037668","url":null,"abstract":"<p><p>We tested the asymmetric polyamide hollow fiber as the filter in the hemofiltration unit. Effective membrane thickness was 1mu, the diameter of the hollow fiber was 600mu, and the total surface was 1 m2. Membrane cutoff was determined at 13,000 daltons molecular weight. A fully automated system was used to replace the volume of ultrafiltrate with a balanced electrolyte solution. Clearance rates for BUN, creatinine, uric acid, and inorganic phosphate were calculated at 70-75 ml/min when prediluting (i.e., when balanced electrolyte solution is admitted to the arterial line of the extracorporeal circuit). Clearance rate for inulin was determined at 23 ml/min. Sieving coefficients for small molecular weight solutes were determined at 1.0 and for inulin 0.4. This decrease is explained by the development of a secondary protein layer and by unflavorable streaming conditions inside the hollow fiber. The ultrafiltrate remained free of protein.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 7","pages":"727-36"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709037668","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11811852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The doctor-patient relationship as it pertains to patients with terminal renal failure.","authors":"M Viederman","doi":"10.3109/08860227709082387","DOIUrl":"https://doi.org/10.3109/08860227709082387","url":null,"abstract":"","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"1 8","pages":"749-55"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227709082387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11811854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}