Thoracic research and practice最新文献

{"title":"Integration of CURB-65 and CT Severity Score for Prognostic Prediction in Community-acquired Pneumonia.","authors":"Ökkeş Gültekin, Orhan Özçekici, İnan Arslantaş","doi":"10.4274/ThoracResPract.2026.2026-5-6","DOIUrl":"10.4274/ThoracResPract.2026.2026-5-6","url":null,"abstract":"<p><strong>Objective: </strong>This study compared confusion, urea, respiratory rate, blood pressure, age ≥65 years (CURB-65) and computed tomography severity score (CTSS) for predicting 30-day mortality, intensive care unit (ICU) admission, and length of hospital stay in patients with community-acquired pneumonia (CAP) and assessed whether CTSS added prognostic value to CURB-65.</p><p><strong>Material and methods: </strong>This retrospective study included 456 adults with CT-confirmed CAP. CURB-65 and CTSS were calculated. Multivariable logistic regression and receiver operating characteristic analyses were performed for 30-day mortality and ICU admission, and area under the curve (AUC) values were compared using the DeLong test.</p><p><strong>Results: </strong>For mortality prediction, the AUC values were 0.894 for CURB-65, 0.762 for mean CTSS, and 0.909 for the combined mortality model. The combined model did not significantly outperform CURB-65 (<i>P</i> = 0.081). For ICU admission, the AUC values were 0.851, 0.716, and 0.881, respectively; the combined ICU model significantly outperformed CURB-65 (<i>P</i> = 0.003). The mean CTSS was independently associated with mortality and ICU admission, but was not associated with length of hospital stay.</p><p><strong>Conclusion: </strong>CURB-65 remained a strong and practical predictor of mortality and ICU admission in CAP. Mean CTSS provided additional prognostic information for mortality and ICU admission, but not for length of hospital stay. The combined mortality model did not significantly improve discrimination compared with CURB-65 alone, whereas the combined ICU model did significantly improve discrimination in predicting ICU admission.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":"45-52"},"PeriodicalIF":0.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Assessment and Outcomes Across Respiratory Diseases.","authors":"Gaye Ulubay, Begüm Ergan","doi":"10.4274/ThoracResPract.2026.2026.071026","DOIUrl":"10.4274/ThoracResPract.2026.2026.071026","url":null,"abstract":"","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":"27 Spec Issue 1","pages":"1-3"},"PeriodicalIF":0.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: Comparative Clinical Outcomes of Nintedanib and Pirfenidone in Idiopathic Pulmonary Fibrosis: A Five-Year Real-Life Study.","authors":"Ayça Yanalak, Onur Yazıcı","doi":"10.4274/ThoracResPract.2026.2026-8-14","DOIUrl":"https://doi.org/10.4274/ThoracResPract.2026.2026-8-14","url":null,"abstract":"","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Culturally Adapted Floor-to-Stand Exercises for COPD: A Quasi-experimental Study.","authors":"Redouene Sid Ahmed Benazzouz, Massinissa Benyagoub, Hanane Meriem Fatmi, Aicha Zenikheri, Lyna Lagraa, Mohamed Safouane Benazzouz, Faiza Hadjersi, Atef Litim, Mounir Ould Setti","doi":"10.4274/ThoracResPract.2026.2026-2-11","DOIUrl":"10.4274/ThoracResPract.2026.2026-2-11","url":null,"abstract":"<p><strong>Objective: </strong>Conventional pulmonary rehabilitation remains difficult to access in many low-resource settings because of practical, geographic, and sociocultural barriers. Accordingly, floor-to-stand exercises (FSE) were developed as an equipment-free program centered on repeated floor-to-stand transitions that are commonly performed in daily life in North Africa. The main objective of the present study was to estimate program completion rates, identify predictors of non-completion, and describe clinical, functional, and peripheral muscle outcomes in chronic obstructive pulmonary disease (COPD) outpatients with documented difficulty rising from the floor.</p><p><strong>Material and methods: </strong>In this prospective, quasi-experimental pilot study, COPD outpatients participated in the 9-week progressive FSE program. Completion was defined as ≥22 floor-to-stand transitions/day during weeks 7-9. Assessments were performed at baseline and at day 63, and outcomes were compared between completers and non-completers.</p><p><strong>Results: </strong>Fifteen COPD outpatients were included; the completion rate was 46.7% (7/15). Completers had lower baseline Borg CR10 scores (6.0 vs. 7.5; <i>P</i> = 0.047) and higher 6-minute walk distance (330 vs. 261 m; <i>P</i> = 0.037). On day 63, completers improved on the modified Medical Research Council Dyspnea Scale (-2.0; <i>P</i> = 0.015), Borg CR10 (-3.0; <i>P</i> = 0.011), and COPD assessment test (-8.0; <i>P</i> = 0.008), whereas non-completers improved only on the Borg CR10 (-2.0; <i>P</i> = 0.020). Functional tests and peripheral muscle outcomes showed no consistent changes overall.</p><p><strong>Conclusion: </strong>The FSE was feasible and safe in this study, with improvements primarily in symptoms and disease impact. Larger controlled studies are needed to confirm the effectiveness and optimize adherence. Trial registration: ClinicalTrials.gov NCT07277855.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":"27-36"},"PeriodicalIF":0.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation, Cultural Adaptation, and Validation of the Turkish Version of the St George's Respiratory Questionnaire for Idiopathic Pulmonary Fibrosis (SGRQ-I).","authors":"Esra Pehlivan, Zeynep Betül Özcan, Cahidenur Koçak, Fulya Senem Karaahmetoğlu, Melih Zeren, Ramazan Eren, Barış Demirkol, Umut İlhan, Halit Çınarka, Erdoğan Çetinkaya","doi":"10.4274/ThoracResPract.2026.2026-6-11","DOIUrl":"10.4274/ThoracResPract.2026.2026-6-11","url":null,"abstract":"<p><strong>Objective: </strong>Idiopathic pulmonary fibrosis (IPF) substantially impairs health-related quality of life (HRQoL). The IPF-specific St George's Respiratory Questionnaire (SGRQ-I) is not available in Turkish. This study aimed to translate, culturally adapt, and validate the SGRQ-I for Turkish-speaking patients with IPF.</p><p><strong>Material and methods: </strong>Following international guidelines, the SGRQ-I underwent forward translation, reconciliation, back translation, developer review, and cognitive debriefing. Adult patients with IPF were consecutively recruited. Validity was assessed against the Turkish SGRQ and by examining associations with forced vital capacity (FVC), diffusing capacity for carbon monoxide (DLCO), the six-minute walk test (6MWT), gender-age-physiology (GAP) stage, modified Medical Research Council (mMRC) grade, and long-term oxygen therapy (LTOT) status. Test-retest reliability was assessed over seven days in clinically stable patients.</p><p><strong>Results: </strong>One hundred eighty patients were included (mean age 66.3±10.0 years; 36% male). Agreement with the SGRQ was excellent for the activities, impact, and total scores [intraclass correlation coefficients (ICC) >0.90] and moderate for the symptoms score. The SGRQ-I total score was significantly correlated with FVC% (r = -0.476), DLCO% (r = -0.406), and 6MWT distance (r = -0.462, all <i>P</i> < 0.001). SGRQ-I scores differed significantly across groups stratified by DLCO%, GAP stage, mMRC grade, and LTOT status (<i>P</i> < 0.01). Test-retest reliability was good to excellent, with ICCs ranging from 0.891 to 0.962.</p><p><strong>Conclusion: </strong>The Turkish SGRQ-I is a valid and reliable instrument for assessing HRQoL in IPF, supporting its use in clinical practice and multinational research.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":"27 Spec Issue 1","pages":"37-44"},"PeriodicalIF":0.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Frequency of Smoking Status Inquiries: A Cross-sectional Analysis.","authors":"Ömer Faruk Özceylan, Rumeysa Betül Kaya, Zeynep Uzun, Turan Set","doi":"10.4274/ThoracResPract.2026.2026-5-14","DOIUrl":"https://doi.org/10.4274/ThoracResPract.2026.2026-5-14","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the frequency with which smoking status was inquired about and smoking cessation advice was provided during patients' previous outpatient clinic visits.</p><p><strong>Material and methods: </strong>This cross-sectional study was conducted at the Department of Family Medicine, Karadeniz Technical University Faculty of Medicine. Patients aged 18 years or older who voluntarily applied to the family medicine outpatient clinic were included. A total of 384 participants were administered a questionnaire, prepared by the researchers, that assessed sociodemographic characteristics and inquired about smoking status during previous visits, using the face-to-face interview method.</p><p><strong>Results: </strong>The mean age of the participants was 30±12.2 years, and 65.1% (n = 250) were female. Active smoking was reported by 22.1% (n = 85) of the participants. The rate of inquiry about smoking status at the participants' most recent outpatient visit was 28.4% (n = 109). Among current smokers, 28.2 (n = 24) received smoking cessation advice. Among current smokers, 11.8% (n = 10) had never received smoking cessation advice during previous medical encounters.</p><p><strong>Conclusion: </strong>Inquiring about smoking status is a crucial step that should not be overlooked during any medical consultation. To provide effective smoking cessation recommendations, it is essential to identify tobacco users. Therefore, every patient encounter should be used as an opportunity for intervention.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Pleural Breach and Perioperative and Long-Term Outcomes after Thymectomy for Myasthenia Gravis: A Two-Center Retrospective Study.","authors":"Muhammad Shoaib Nabi, Zeeshan Sarwar, Rafay Shamshad, Hassan Iftikhar","doi":"10.4274/ThoracResPract.2026.2026-3-3","DOIUrl":"https://doi.org/10.4274/ThoracResPract.2026.2026-3-3","url":null,"abstract":"<p><strong>Objective: </strong>Thymectomy is an established treatment for myasthenia gravis and thymic tumors. This study evaluated the impact of pleural breach on perioperative pleural-related morbidity and long-term neurologic and oncologic outcomes following thymectomy.</p><p><strong>Material and methods: </strong>A retrospective multicenter review of 455 patients who underwent thymectomy between January 2005 and December 2024 was conducted at Services Hospital and Surgimed Hospital, Lahore, Pakistan. Patients underwent either a partial transsternal thymectomy (n = 273) or a video-assisted thoracoscopic surgery (VATS) thymectomy (n = 182). The primary outcome was pleural-related postoperative morbidity. Secondary outcomes included neurologic remission, recurrence-free survival (RFS), postoperative complications, and hospital stay.</p><p><strong>Results: </strong>Pleural breach occurred in all VATS cases and incidentally in 29 (10.6%) transsternal cases. VATS thymectomy was associated with lower blood loss (<i>P</i> < 0.001) and shorter hospital stay (<i>P</i> < 0.001), but with longer operative time (<i>P</i> < 0.001). Pleural-related complications were more frequent following pleural breach, but were generally transient and were managed conservatively. On multivariable analysis, pleural breach independently predicted pleural-related morbidity [odds ratio (OR): 2.6, <i>P</i> = 0.006]. The combined proportion of patients achieving complete stable remission, pharmacologic remission, or clinical improvement exceeded 90%. Neurologic remission and 5-year RFS were comparable between groups (<i>P</i> = 0.612 and <i>P</i> = 0.538, respectively).</p><p><strong>Conclusion: </strong>Pleural breach during thymectomy was independently associated with increased transient pleural-related postoperative morbidity (OR: 2.6). However, these complications were generally self-limited and managed conservatively. Long-term neurologic remission and RFS were comparable between surgical approaches, but these findings should be interpreted cautiously given the retrospective observational design.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic Surgeon Density in Türkiye in the Global Context: Implications for Workforce Planning.","authors":"Necati Çıtak","doi":"10.4274/ThoracResPract.2026.2026-2-7","DOIUrl":"https://doi.org/10.4274/ThoracResPract.2026.2026-2-7","url":null,"abstract":"<p><strong>Objective: </strong>Ten years ago, evidence demonstrated that the number of thoracic surgeons in Türkiye was excessive. In the intervening period, health policies have continued to significantly increase the number of thoracic surgeons. It is estimated that this number will almost double within the next ten years. This study aims to investigate, using scientific data, the ideal number of thoracic surgeons required in Türkiye.</p><p><strong>Material and methods: </strong>Thoracic surgery workforce requirements were estimated using national data on annual outpatient visits and hospitalization rates; data from the Turkish Statistical Institute; specialist physician growth rates; and international data from Europe, the Americas, and global sources, according to service targets, population growth, high human development index countries, and global benchmarks.</p><p><strong>Results: </strong>According to Ministry of Health data, 693 licensed thoracic surgeons are currently registered as active physicians in Türkiye. In addition, 353 residents are undergoing specialist training in thoracic surgery. Based on annual outpatient visits (1,100,000) and hospitalization rate (5%), the required number of thoracic surgeons was calculated as 589. Based on specialist physician growth and population growth over the past decade, the required numbers were estimated as 586 and 589, respectively. According to European, American, and global benchmarks, the required numbers were 267, 351, and 102, respectively. Overall, calculations using all methods indicate a workforce excess ranging from 15% to 81.9%.</p><p><strong>Conclusion: </strong>The number of thoracic surgeons in Türkiye is substantially higher than the estimated requirements and is expected to increase further due to ongoing residency training. National workforce planning based on objective criteria is needed to ensure alignment between training capacity and healthcare needs.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breathe Easier: Evaluating Serratus Anterior Plane Block for Rib Fracture Analgesia-A Systematic Review and Meta-analysis.","authors":"Clara Alverina, Safina Fairuz Salwaa, Syaogi Ahmed 'Azizy, Pesta Parulian Maurid Edwar","doi":"10.4274/ThoracResPract.2026.2026-1-12","DOIUrl":"https://doi.org/10.4274/ThoracResPract.2026.2026-1-12","url":null,"abstract":"<p><strong>Objective: </strong>Rib fractures may cause severe pain that impairs ventilation, increases pulmonary complications, and lengthens hospitalization. Conventional analgesic techniques have several limitations, whereas the serratus anterior plane block (SAPB) offers a simpler, ultrasound-guided regional anesthesia alternative. This systematic review and meta-analysis examined whether SAPB improves pain control and reduces opioid use and hospitalization duration.</p><p><strong>Material and methods: </strong>A systematic review and meta-analysis were performed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A literature search of PubMed, Scopus, EBSCO, Taylor & Francis, Web of Science, and ScienceDirect was conducted to identify randomized and observational studies comparing SAPB with opioid-based analgesia or other regional blocks in patients with rib fracture pain. The primary outcome was pain severity visual analogue scale/numeric rating scale (VAS/NRS) at predefined time points, whereas opioid consumption and hospital length of stay (LOS) served as secondary outcomes. Given the variability of pain assessment scales across studies (NRS 0-10 and VAS 0-100), continuous outcomes were pooled as standardized mean differences (SMDs) using a random-effects model. Seven studies comprising 611 patients met the inclusion criteria and were included in the analysis.</p><p><strong>Results: </strong>The meta-analysis showed that baseline pain scores were broadly comparable between SAPB and comparators, with no statistically significant difference overall (baseline SMD: 0.18; <i>P</i> = 0.25) or within either subgroup. Compared with opioids, SAPB was associated with significantly lower pain scores at 3 hours (SMD: -0.40; <i>P</i> = 0.04) and, in the opioid subgroup, at 12 hours (SMD: -0.44; <i>P</i> = 0.002). Overall pooled estimates at 6, 12, and 24 hours did not reach statistical significance owing to substantial heterogeneity (I² 87-96%). Compared with other regional blocks, SAPB was associated with higher pain scores at 6 hours (SMD: 0.85; <i>P</i> = 0.004), whereas the comparison at 24 hours was inconclusive, with the overall estimate not statistically significant (SMD: -0.76; <i>P</i> = 0.15). A pooled analysis also showed a significant reduction in opioid consumption with SAPB (SMD: -0.35; 95% confidence interval: -0.67 to -0.02; <i>P</i> = 0.04). Findings on hospital LOS were inconsistent across studies and remain inconclusive.</p><p><strong>Conclusion: </strong>Overall, low-certainty evidence suggests that SAPB may provide effective and longer-lasting analgesia, reduce opioid requirements, and support respiratory function, indicating a potential role as an adjunct in the management of rib fracture pain.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Prognostic Nutritional Index in Conjunction with Lung Cancer Stage and PET-CT SUVmax.","authors":"İlknur Kaya, Ümran Erbay, Şebnem Emine Parspur, Feride Marım, Mehmet Doğan, Şerife Kaya, Jülide Kan","doi":"10.4274/ThoracResPract.2026.2026-4-7","DOIUrl":"10.4274/ThoracResPract.2026.2026-4-7","url":null,"abstract":"<p><strong>Objective: </strong>Lung cancer is among the malignancies with the highest mortality rates globally, where nutritional and immune status significantly influence disease progression and prognosis. The study aimed to investigate the relationship of the prognostic nutritional index (PNI) with both the maximum standardized uptake value (SUVmax), measured by positron emission tomography-computed tomography, and the clinical stage of lung cancer.</p><p><strong>Material and methods: </strong>Patients who underwent fiberoptic bronchoscopy and were diagnosed with lung cancer at the Department of Pulmonology, Kütahya Health Sciences University, between January 1, 2022 and May 31, 2025, were retrospectively evaluated. A total of 241 patients diagnosed with lung cancer via bronchoscopy were evaluated; of these, 205 patients diagnosed with non-small-cell lung cancer (n = 205) were assessed according to stage.</p><p><strong>Results: </strong>A total of 241 lung cancer patients were included; the mean age was 68.35±8.52 years and 95.0% were male. The mean PNI was 41.41±9.50 and the mean primary tumor SUVmax was 10.53±5.22. PNI and primary tumor SUVmax showed a very weak negative association that did not reach statistical significance (Spearman ρ = -0.127; <i>P</i> = 0.055). Clinical stage was positively associated with SUVmax (ρ = 0.253; <i>P</i> < 0.001) and negatively associated with PNI (ρ = -0.186; <i>P</i> = 0.007).</p><p><strong>Conclusion: </strong>Higher clinical stage was associated with higher primary tumor SUVmax and lower PNI. The association between PNI and SUVmax was weak and not statistically significant; therefore, it should not be considered clinically discriminative on its own. PNI may serve as an adjunctive indicator of nutritional and immune status, but prospective studies with survival outcomes and multivariable adjustment are required before it can be used as a prognostic or staging tool.</p>","PeriodicalId":75221,"journal":{"name":"Thoracic research and practice","volume":" ","pages":"294-299"},"PeriodicalIF":0.8,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}