Revue francophone des laboratoires : RFL最新文献

{"title":"Actualités sur la fièvre Q","authors":"Maxime Colson ,&nbsp;Matthieu Million ,&nbsp;Pierre-Edouard Fournier ,&nbsp;Sophie Edouard","doi":"10.1016/S1773-035X(25)76407-2","DOIUrl":"10.1016/S1773-035X(25)76407-2","url":null,"abstract":"<div><h3>Résumé</h3><div><em>Coxiello burnetii</em> est une bactérie intracellulaire stricte capable de survivre dans le milieu extérieur. La primo-infection ou fièvre Q aiguë peut se manifester par une fièvre isolée, un syndrome pseudogrippal, une hépatite ou une pneumopathie. La présence d’anticorps antiphospholipides doit systématiquement être recherchée car ils viennent fréquemment compliquer les fièvres Q aiguës et sont impliqués notamment dans la survenue de thromboses, endocardites aiguës, méningites. Les patients porteurs de valvulopathies, prothèses cardiaques ou vasculaires sont plus à risques d’évolution vers des formes focalisées persistantes avec risque important de mortalité en l’absence de traitement. Le diagnostic microbiologique repose sur la sérologie et la PCR mais doit être complété par l’anatomopathologie et l’imagerie. La recherche systématique d’une valvulopathie par échographie cardiaque est primordiale afin de prévenir l’évolution vers l’endocardite en administrant une antibioprophylaxie prolongée si nécessaire. En cas de mauvaise évolution sérologique, le PET scanner est recommandé afin de détecter la présence de foyers infectieux persistants et permet un diagnostic très précoce. L’administration per os de doxycyline associée à I’hydroxychloroquine permet de contrôler les infections chroniques dans la plupart des cas mais nécessite une administration prolongée sur une à plusieurs années.</div></div><div><h3>Abstract</h3><div><em>Coxiella burnetii</em> is a strict intracellular bacterium that is able to survive in the environment. Primary infection, or acute Q fever, may manifest as an isolated fever, flu-like syndrome, hepatitis or pneumopathy. The presence of anti-phos-pholipid antibodies should be systematically searched, as they frequently complicate acute Q fever and could be implicated in thrombosis, acute endocarditis or meningitis…. Patients presenting with valvulopathy, cardiac or vascular prostheses are at greater risk of developing persistent focal forms, with a high risk of mortality in the absence of treatment. Microbiological diagnosis is based on serology and PCR, but should be complemented by anatomopathology and imaging. The search for valvulopathy by cardiac echography is essential to prevent progression to endocarditis, with prolonged antibiotic prophylaxis if necessary. In case of unsatisfactory evolution of serological titers, PET scan is recommended to detect or confirm/invalidate the presence of persistent infectious foci, and enable an earliest diagnosis. Oral administration of doxycyline combined with hydroxychloroquine allow to control chronic infections in most cases, but requires prolonged administration over one or more years.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Pages 39-49"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le cannabis, c’est pas bon pour le cœur !","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76391-1","DOIUrl":"10.1016/S1773-035X(25)76391-1","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 10"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un nouveau récepteur : un non-opioïde pour ne plus avoir mal","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76393-5","DOIUrl":"10.1016/S1773-035X(25)76393-5","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 11"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tu seras un homme mon garçon, mon fils","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76394-7","DOIUrl":"10.1016/S1773-035X(25)76394-7","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 11"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La malbouffe brouillerait la réponse cérébrale à l’insuline","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76386-8","DOIUrl":"10.1016/S1773-035X(25)76386-8","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 6"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plus de trois heures d’attente pour la moitié des patients","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76390-X","DOIUrl":"10.1016/S1773-035X(25)76390-X","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 9"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Handicap 2025 Le guide pratique","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76396-0","DOIUrl":"10.1016/S1773-035X(25)76396-0","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 12"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Textes juridiques","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76397-2","DOIUrl":"10.1016/S1773-035X(25)76397-2","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 13"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apnées du sommeil et maladie de Parkinson : la CPAP protectrice ?","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76392-3","DOIUrl":"10.1016/S1773-035X(25)76392-3","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Page 10"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les rickettsioses","authors":"Diane Fournier ,&nbsp;Jacques Sevestre ,&nbsp;Pierre-Edouard Fournier ,&nbsp;Sophie Edouard","doi":"10.1016/S1773-035X(25)76406-0","DOIUrl":"10.1016/S1773-035X(25)76406-0","url":null,"abstract":"<div><h3>Résumé</h3><div>Les rickettsioses sont des infections zoonotiques causées par les bactéries des genres <em>Rickettsia</em> et <em>Orientia</em> et transmises par des arthropodes. Elles sont présentes dans le monde entier mais la distribution de chaque espèce est calquée sur celle de son réservoir et/ou vecteur. Les rickettsioses sont l’une des principales causes d’infections associées aux voyages. Elles peuvent être difficiles à diagnostiquer car la plupart des patients présentent des symptômes bénins, mais certaines, comme la fièvre boutonneuse méditerranéenne, présentent un tableau clinique caractéristique. En revanche, le typhus épidémique et la fièvre pourprée des montagnes Rocheuses sont associés à une mortalité importante.</div></div><div><h3>Abstract</h3><div>Rickettsioses are zoonotic infections caused by bacteria from the genera <em>Rickettsia</em> and <em>Orientia</em>, and transmitted by arthropods.They are present all over the world but the distribution of each species parallels that of its reservoir(s) and/or vector(s). Rickettsioses are one of the leading causes of travel-related infections.They may be difficult to diagnose because most patients have mild symptoms, but some, such as Mediterranean spotted fever, have a characteristic clinical presentation. However, epidemic typhus and Rocky Mountain spotted fever are associated with significant mortality.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 573","pages":"Pages 30-38"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}