PCN reports : psychiatry and clinical neurosciences最新文献

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Possible influence of reflecting on the tense of the client's utterances: A preliminary finding. 反思对来访者话语时态的可能影响:初步发现。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-07 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70407
Tomoyuki Sugita, Hiromi Tsujii, Takao Iwanami, Suimei Morikawa, Tadafumi Kato
{"title":"Possible influence of reflecting on the tense of the client's utterances: A preliminary finding.","authors":"Tomoyuki Sugita, Hiromi Tsujii, Takao Iwanami, Suimei Morikawa, Tadafumi Kato","doi":"10.1002/pcn5.70407","DOIUrl":"10.1002/pcn5.70407","url":null,"abstract":"<p><strong>Aim: </strong>Open Dialogue (OD), developed in Finland, has gained attention in psychiatric care for its emphasis on human rights. However, quantitative research remains limited, and its implementation in Japan is still at an early stage. Reflecting, originally developed in Norway, is a core element of OD's dialogical practice and has shown promise, yet studies on its mechanisms remain scarce.</p><p><strong>Methods: </strong>This study examined how reflecting is associated with changes in the tense structure of client utterances. Audio from outpatient sessions was transcribed, and utterances were categorized into four tense types: future, present, recent past, and past. Changes before and after reflecting were analyzed using repeated measures ANOVA and Wilcoxon tests.</p><p><strong>Results: </strong>Results showed that past-oriented utterances significantly increased in the reflecting group, while no significant changes occurred in the individual consultation group.</p><p><strong>Conclusion: </strong>These findings suggest that reflecting may be associated with increased references to past experiences, which may be related to self-reflection as one aspect of a deepening dialogical process.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70407"},"PeriodicalIF":1.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serial FDG-PET in probable seronegative autoimmune encephalitis presenting as severe behavioral regression in a child with autism. 系列FDG-PET在可能的血清阴性自身免疫性脑炎中表现为自闭症儿童严重的行为倒退。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-07 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70395
Edouard Guez, Theodore Falempin, Cyril Hanin, Alison Arbouche, Rony Boucher, Myriam Hamdi, Marie Raffin, Angèle Consoli, Aurélie Kas, Marianna Giannitelli, David Cohen
{"title":"Serial FDG-PET in probable seronegative autoimmune encephalitis presenting as severe behavioral regression in a child with autism.","authors":"Edouard Guez, Theodore Falempin, Cyril Hanin, Alison Arbouche, Rony Boucher, Myriam Hamdi, Marie Raffin, Angèle Consoli, Aurélie Kas, Marianna Giannitelli, David Cohen","doi":"10.1002/pcn5.70395","DOIUrl":"10.1002/pcn5.70395","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune encephalitis in children may present with predominant psychiatric and behavioral symptoms, creating diagnostic challenges, particularly in patients with pre-existing autism spectrum disorder. Seronegative forms are especially difficult to recognize because neuronal autoantibodies are not detected, and diagnostic overshadowing may delay consideration of immune-mediated etiologies.</p><p><strong>Case presentation: </strong>We report the case of an 11-year-old boy of Turkish background living in France, with autism and normal intelligence, who developed severe subacute behavioral and cognitive regression. Symptoms included explosive aggression, self-injurious behavior, obsessive-compulsive-like behavioral loops, psychotic-like features, agitated catatonic deterioration from baseline, loss of adaptive skills, and marked functional decline. The condition was resistant to intensive psychiatric care and multiple psychotropic treatments. Etiological assessment revealed focal epilepsy, cerebrospinal fluid abnormalities, and abnormal brain fluorodeoxyglucose positron emission tomography (FDG-PET) findings, while extensive work-up excluded infectious, metabolic, genetic, systemic autoimmune, and oncological causes. Neuronal autoantibodies were negative in serum and cerebrospinal fluid. A cautious diagnosis of probable seronegative autoimmune encephalitis was retained based on the clinical course, focal epilepsy, serial FDG-PET abnormalities, follow-up cerebrospinal fluid findings, exclusion of alternative etiologies, and expert consensus. Intravenous immunoglobulin therapy was associated with progressive but partial clinical improvement, and rituximab was introduced after a response plateau.</p><p><strong>Conclusion: </strong>This case highlights the risk of diagnostic overshadowing in children with autism presenting with severe, treatment-resistant behavioral or catatonic regression. Immune-mediated etiologies should be considered even in the absence of detectable autoantibodies. Serial FDG-PET may support diagnostic reasoning and follow-up, while remaining nonspecific and insufficient as diagnostic proof in isolation.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70395"},"PeriodicalIF":1.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing mortality risk in narcolepsy: Evidence from population studies. 评估发作性睡病的死亡风险:来自人群研究的证据。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-07 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70411
Nawris Alhassan, Susmin Karki, Jagdish Lal
{"title":"Assessing mortality risk in narcolepsy: Evidence from population studies.","authors":"Nawris Alhassan, Susmin Karki, Jagdish Lal","doi":"10.1002/pcn5.70411","DOIUrl":"10.1002/pcn5.70411","url":null,"abstract":"<p><p>Narcolepsy is a chronic neurologic sleep disorder associated with excessive daytime sleepiness, cataplexy, and a higher prevalence of cardiovascular and psychiatric comorbidities. While these factors may predispose individuals to adverse events, observational studies evaluating mortality in narcolepsy have yielded inconsistent results. This systematic review and meta-analysis aimed to quantify the all-cause mortality risk in patients with narcolepsy compared to matched controls. A systematic literature search of PubMed, Embase, Scopus, and Web of Science was conducted up to February 2026 for studies reporting quantitative mortality metrics (Risk Ratios [RR] and Hazard Ratios [HR]) in narcolepsy. Pooled effect estimates were calculated using random- and fixed-effects models. We also performed sensitivity analyses and subgroup analyses based on geographic region (Western vs. Asian) and age (Pediatric vs. Adult/Mixed) to explore heterogeneity. Five studies comprising 212,596 patients with narcolepsy and 526,688,615 controls were included in the primary analysis. The overall pooled RR for mortality was 1.25 (95% CI: 0.98 to 1.61; <i>P</i> = 0.08), demonstrating no statistically significant increase in risk, albeit with substantial heterogeneity (<i>I</i> <sup>2</sup> = 83%). A sensitivity analysis excluding one heavily weighted outlier (Ohayon et al., 2014) reduced heterogeneity (<i>I</i> <sup>2</sup> = 8%; RR = 1.09, 95% CI: 0.95 to 1.24; <i>P</i> = 0.22), showing that the results depend heavily on a single administrative dataset rather than proving narcolepsy carries no mortality risk. Furthermore, the pooled HR for mortality over time across three studies was 1.20 (95% CI: 0.82 to 1.76; <i>P</i> = 0.34). Subgroup analyses revealed no significant variation in mortality risk between Western and Asian populations (<i>P</i> = 0.55) or between pediatric and adult cohorts (<i>P</i> = 0.36). Current evidence does not prove narcolepsy carries a normal life expectancy. Instead, all-cause mortality risk remains uncertain due to fragile data and a lack of cause-specific findings. Because narcolepsy involves serious cardiometabolic, psychiatric, accident, and medication risks, ongoing patient risk management is required.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70411"},"PeriodicalIF":1.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nationwide trends in cigarette, heated tobacco product, e-cigarette, and multiple-product use in Japan 2017-2025. 2017-2025年日本香烟、加热烟草产品、电子烟和多产品使用的全国趋势。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-04 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70409
Satomi Mizuno, Satoshi Inoura, Toshihiko Matsumoto, Takuya Shimane
{"title":"Nationwide trends in cigarette, heated tobacco product, e-cigarette, and multiple-product use in Japan 2017-2025.","authors":"Satomi Mizuno, Satoshi Inoura, Toshihiko Matsumoto, Takuya Shimane","doi":"10.1002/pcn5.70409","DOIUrl":"10.1002/pcn5.70409","url":null,"abstract":"<p><strong>Aim: </strong>To describe nationally representative trends in overall and product-specific tobacco use, including cigarettes, heated tobacco products (HTPs), and electronic cigarettes (e-cigarettes), in Japan from 2017 to 2025.</p><p><strong>Methods: </strong>Data came from repeated cross-sectional nationwide surveys of the Japanese population using stratified two-stage random sampling. Self-administered questionnaires assessed tobacco use. Past-30-day prevalence of overall, product-specific, and multiple-product use was estimated using survey-weighted logistic regression, with marginal predicted prevalence standardized to the 2025 age-sex structure.</p><p><strong>Results: </strong>Among 16,499 participants, overall past-30-day tobacco use declined from 24.3% (95% confidence interval [CI]: 22.6-26.0%) in 2017 to 21.0% (CI: 19.4-22.7%) in 2025. Cigarette use decreased from 20.7% (CI: 19.0-22.3%) to 12.3% (CI: 11.1-13.6%), whereas HTP use increased from 5.3% (CI: 4.4-6.1%) to 11.7% (CI: 10.3-13.0%). e-cigarette use remained low, ranging from 0.7% to 1.3%. The most common multiple-product pattern was concurrent cigarette and HTP use, increasing from 2.5% (CI: 1.9-3.1%) to 4.1% (CI: 3.3-4.9%).</p><p><strong>Conclusion: </strong>Overall tobacco use in Japan declined modestly during 2017-2025, alongside a marked decrease in cigarette use and an increase in HTP use, while e-cigarette use remained limited. These findings suggest a shift in tobacco use, with increased HTP use partially offsetting reductions in cigarette smoking.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70409"},"PeriodicalIF":1.3,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13543303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demographic characteristics and psychosocial backgrounds of patients with dextromethorphan overdose in Japan: A multicenter prospective observational study. 日本右美沙芬过量患者的人口学特征和社会心理背景:一项多中心前瞻性观察研究。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-03 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70406
Hironori Katsuki, Yoshito Kamijo, Michiko Takai, Saeko Kohara, Hidetada Fukushima, Yuta Mizuno, Hidenobu Ochiai, Norio Otani, Dai Taguchi, Takuya Shimane, Ryoko Kyan
{"title":"Demographic characteristics and psychosocial backgrounds of patients with dextromethorphan overdose in Japan: A multicenter prospective observational study.","authors":"Hironori Katsuki, Yoshito Kamijo, Michiko Takai, Saeko Kohara, Hidetada Fukushima, Yuta Mizuno, Hidenobu Ochiai, Norio Otani, Dai Taguchi, Takuya Shimane, Ryoko Kyan","doi":"10.1002/pcn5.70406","DOIUrl":"10.1002/pcn5.70406","url":null,"abstract":"<p><strong>Aim: </strong>Few studies in Japan have described young patients presenting to emergency departments after dextromethorphan overdose in detail. Therefore, we aimed to investigate the demographic characteristics and psychosocial backgrounds of patients who presented to emergency departments in Japan after dextromethorphan overdose.</p><p><strong>Methods: </strong>This was a multicenter, prospective, observational study with nonconsecutive enrollment. A standardized questionnaire regarding dextromethorphan overdose and the Drug Abuse Screening Test-20 (DAST-20) were administered in eight emergency departments in Japan. Continuous variables are presented as medians and interquartile ranges.</p><p><strong>Results: </strong>In total, 78 patients were included. The median age was 20 years (17.0-22.0), and 64 patients (82.1%) were female. Fifty-six (71.8%) patients engaged in social activities. Fifty-one patients (65.4%) stated that the purpose of the overdose was suicide/self-harm. The number of patients who reported that the source of information on dextromethorphan overdose was social networking services and internet searches was 27 (35.1%) and 29 (37.7%), respectively. Fifty-eight patients (74.4%) reported that dextromethorphan was purchased from a retail store. Among 66 respondents, 40 (60.6%) had moderate or higher DAST-20 scores. On comparing the younger group aged 10-19 years (<i>n</i> = 38) and the older group aged ≥20 years (<i>n</i> = 40), the number of patients who indicated that the source of information on dextromethorphan overdose was internet searches in the former group (19, 50.0%) was significantly higher than that in the latter group (10, 25.0%).</p><p><strong>Conclusion: </strong>Dextromethorphan overdose predominantly involved young women, and drug-related problems were common.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70406"},"PeriodicalIF":1.3,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148889751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facial emotional expression in response to alcohol-promoting commercials in individuals with alcohol use disorder: A pilot study. 酒精使用障碍个体对酒精促销广告反应的面部情绪表达:一项初步研究
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-03 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70405
Takefumi Ueno, Naho Nakayama, Shou Fukushima, Kazunori Matsuguchi, Kazuhiro Tojiki, Chenyu Qian, Shisei Tei, Hidehiko Takahashi, Junya Fujino
{"title":"Facial emotional expression in response to alcohol-promoting commercials in individuals with alcohol use disorder: A pilot study.","authors":"Takefumi Ueno, Naho Nakayama, Shou Fukushima, Kazunori Matsuguchi, Kazuhiro Tojiki, Chenyu Qian, Shisei Tei, Hidehiko Takahashi, Junya Fujino","doi":"10.1002/pcn5.70405","DOIUrl":"10.1002/pcn5.70405","url":null,"abstract":"","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70405"},"PeriodicalIF":1.3,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148889746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of depressive symptoms and anxious distress between major depressive disorder and bipolar disorder using the CUDOS-A. 重度抑郁障碍与双相情感障碍抑郁症状与焦虑困扰的比较
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-02 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70403
Kazufumi Oishi, Yasuyuki Matsumoto, Yumi Aoki, Yoshikazu Takaesu, Masami Murao, Taku Maruki, Takashi Tsuboi, Masahiro Nakano, Koichiro Watanabe, Hitoshi Sakurai
{"title":"Comparison of depressive symptoms and anxious distress between major depressive disorder and bipolar disorder using the CUDOS-A.","authors":"Kazufumi Oishi, Yasuyuki Matsumoto, Yumi Aoki, Yoshikazu Takaesu, Masami Murao, Taku Maruki, Takashi Tsuboi, Masahiro Nakano, Koichiro Watanabe, Hitoshi Sakurai","doi":"10.1002/pcn5.70403","DOIUrl":"10.1002/pcn5.70403","url":null,"abstract":"<p><strong>Aim: </strong>Anxious distress is a clinically important specifier associated with adverse outcomes in mood disorders. This study aimed to compare the prevalence of anxious distress and overall depressive symptoms between patients with major depressive disorder (MDD) and bipolar disorder (BD) using validated self-report measures.</p><p><strong>Methods: </strong>This cross-sectional study included 202 psychiatric outpatients (133 MDD and 69 BD) recruited from seven outpatient clinics in Japan. Participants completed the Clinically Useful Depression Outcome Scale supplemented with the DSM-5 anxious distress specifier (CUDOS-A) and the Quick Inventory of Depressive Symptomatology, Self Report (QIDS-SR). Anxious distress was operationally defined using the CUDOS-A items corresponding to the DSM-5 anxious distress specifier. Group differences in prevalence and mean scores were examined using chi-square tests and independent samples <i>t</i>-tests, respectively.</p><p><strong>Results: </strong>The prevalence of anxious distress was 42.9% in patients with MDD and 43.4% in those with BD, with no significant difference between groups (<i>p</i> = 0.95). No significant differences were observed in the mean CUDOS-A total scores (28.0 ± 19.9 vs. 27.0 ± 17.7, <i>p</i> = 0.57) or the QIDS-SR total scores (13.6 ± 7.6 vs. 12.1 ± 7.4, <i>p</i> = 0.18). Furthermore, all individual items of the CUDOS-A showed no significant differences between the two groups.</p><p><strong>Conclusions: </strong>Both anxious distress and overall depressive symptom severity assessed by self-report measures appear to be comparable between MDD and BD. Although the diagnostic utility of anxious distress for differentiating between the two disorders has not been established, its high prevalence in both groups underscores its clinical significance and supports the need for routine assessment in mood disorders.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70403"},"PeriodicalIF":1.3,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Manic switching is seldom observed during rTMS therapy for unipolar depression: Implications for antidepressant mechanisms. 躁狂转换是很少观察到在rTMS治疗单极抑郁症:对抗抑郁机制的影响。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-09-02 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70402
Yuki Matsuda, Shun Takahashi
{"title":"Manic switching is seldom observed during rTMS therapy for unipolar depression: Implications for antidepressant mechanisms.","authors":"Yuki Matsuda, Shun Takahashi","doi":"10.1002/pcn5.70402","DOIUrl":"10.1002/pcn5.70402","url":null,"abstract":"","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70402"},"PeriodicalIF":1.3,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13536031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catatonia with prominent psychosocial factors: A case report. 心理社会因素突出的紧张症1例。
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-08-25 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70401
Hiroto Noguchi, Yuki Omiya, Masahiro Hishiyama, Mariko Nakau, Sadayuki Hashioka
{"title":"Catatonia with prominent psychosocial factors: A case report.","authors":"Hiroto Noguchi, Yuki Omiya, Masahiro Hishiyama, Mariko Nakau, Sadayuki Hashioka","doi":"10.1002/pcn5.70401","DOIUrl":"10.1002/pcn5.70401","url":null,"abstract":"<p><strong>Background: </strong>Catatonia is a psychomotor syndrome historically linked to schizophrenia but now recognized across diverse psychiatric, medical, and psychosocial contexts. Detailed reports of catatonia arising amid pronounced psychosocial vulnerability remain scarce. We describe catatonia in a patient with co-occurring somatic symptom disorder, functional neurological symptom disorder (FNSD), and dissociative disorder that remitted with pharmacotherapy.</p><p><strong>Case presentation: </strong>A man in his 40's with chronic physical illness and recurrent fears of abandonment by his partner developed functional and dissociative symptoms after his partner's surgery was scheduled and was admitted following the sudden onset of fragmented, childlike speech. No specific neurological or medical cause was identified, and no schizophrenia or mood disorder was present. He developed stupor, mutism, posturing, negativism, mannerisms, and stereotypy, meeting DSM-5-TR criteria for catatonia; the Bush-Francis Catatonia Rating Scale (BFCRS) score was 22. Under lorazepam 3 mg/day and quetiapine 600 mg/day, the BFCRS improved to 3 by hospital Day 34, but worsened during dose reduction of either drug and improved on re-escalation. He was discharged on hospital Day 98 with a BFCRS of 0, with no recurrence at 10 months.</p><p><strong>Conclusion: </strong>Catatonia can arise in patients with co-occurring somatic symptom disorder, FNSD, and dissociative disorder. In this patient, catatonia showed dose-dependent re-emergence during tapering of both lorazepam and quetiapine, with remission on re-escalation. Even when psychosocial factors appear prominent, careful monitoring and gradual dose adjustment may be important for maintaining remission.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 3","pages":"e70401"},"PeriodicalIF":1.3,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical characteristics and risk factors associated with consultation-confirmed delirium in hospitalized patients. 住院患者经会诊确认谵妄的临床特征及相关危险因素
IF 1.3
PCN reports : psychiatry and clinical neurosciences Pub Date : 2026-07-30 eCollection Date: 2026-09-01 DOI: 10.1002/pcn5.70385
Megumi Matsuda, Kazuhiko Yamamuro, Masatsugu Ikeuchi, Akihiro Minami, Izumi Harada, Takahira Yamauchi, Tetsuro Kitamura, Yasuyo Kobayashi, Yukako Ishida, Yusuke Inagaki, Jyunko Minamiguchi, Akira Kido, Takashi Okada
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