PCN reports : psychiatry and clinical neurosciences最新文献

{"title":"Relationships among highly sensitive personality (HSP), neuroticism, mental health, neurodevelopmental traits, and adverse childhood experiences (ACEs).","authors":"Akari Matsuzawa, Tsubasa Sasaki, Eiji Shimizu","doi":"10.1002/pcn5.70322","DOIUrl":"https://doi.org/10.1002/pcn5.70322","url":null,"abstract":"<p><strong>Aim: </strong>Awareness of mental health is important to reduce stigma and discrimination and increase access to care. From the viewpoint of mental health conditions, this study examined the relationships among highly sensitive personality (HSP) traits and neuroticism in the general population.</p><p><strong>Methods: </strong>After obtaining informed consents, an anonymous web-based survey for adult participants with equal data collection across genders and age groups (20s, 30s, and 40s) was conducted using self-report questionnaires about HSP, neuroticism, mental health conditions including depression, anxiety, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), trauma-related stress, adverse childhood experiences (ACEs), and awareness of HSP and neurodevelopmental disorders. Participants were divided into the three groups based on HSP or neuroticism, with low, medium, and high groups defined by the mean value ± 1 SD.</p><p><strong>Results: </strong>Data from 2593 participants were analyzed. High-HSP and high-neuroticism groups exhibited higher levels of depression, anxiety, ASD, ADHD traits, trauma-related stress, and ACEs, compared to the other medium and low groups, respectively. Regarding ACEs, both the high-HSP and high-neuroticism groups showed significantly high rates of psychological abuse and neglect. While the high-neuroticism group showed broad associations across all ACE categories, the high-HSP group showed specific and comparable, or slightly stronger, associations with household mental disorders and physical abuse. In the high-HSP group, more participants answered that being HSP or having a neurodevelopmental disorder was part of their identity.</p><p><strong>Conclusion: </strong>High HSP and high neuroticism show mental health similarities, but HSP uniquely internalizes traits as identity.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70322"},"PeriodicalIF":0.9,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-related differences and influencing factors of acute stress symptoms in university students exposed to suicide.","authors":"Isamu Yamazaki, Tohru Takahashi, Daimei Sasayama, Hiroshi Morita, Shinsuke Washizuka","doi":"10.1002/pcn5.70323","DOIUrl":"https://doi.org/10.1002/pcn5.70323","url":null,"abstract":"<p><strong>Aim: </strong>Although clarifying the immediate psychological impact on students exposed to suicide is essential, standardized suicide postvention protocols in university settings are currently lacking. This study examined the temporal differences and contributing factors in the psychological impact of suicide exposure among university students using postvention records from a single Japanese university.</p><p><strong>Methods: </strong>We collected and analyzed the records of 32 student suicide cases at Shinshu University between 2009 and 2023. Of these, 10 were selected for further analysis based on the availability of both postvention interview records and scores from the Japanese-language version of the Impact of Event Scale-Revised (IES-R-J). Among the 136 students who received postvention support, data from 129 students exposed to suicide were included in the analysis. Time-related differences in the initial IES-R-J scores were analyzed using analysis of variance, and the factors influencing the scores were examined using multiple regression analysis.</p><p><strong>Results: </strong>Postvention was implemented in 17 of 32 suicide cases. In the 10 selected cases, higher IES-R-J scores were associated with being female, discovering or witnessing the suicide, fewer days elapsed since the suicide, a documented relationship with the deceased, and personal vulnerability noted in records.</p><p><strong>Conclusion: </strong>This study identified key factors associated with acute stress responses among university students exposed to suicide. Although symptoms generally decline over time, several factors were associated with increased severity. Suicide prevention in universities should prioritize support for individuals at greater risk based on the risk factors identified in this study.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70323"},"PeriodicalIF":0.9,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase-based analysis of ICD-10 psychiatric diagnoses in outpatients and inpatients after the 2024 Noto Peninsula Earthquake.","authors":"Yumeno Furukawa, Reiko Hashimoto, Hiroaki Kihara, Tatsuya Nagasawa, Yusuke Nitta, Takashi Uehara","doi":"10.1002/pcn5.70319","DOIUrl":"https://doi.org/10.1002/pcn5.70319","url":null,"abstract":"<p><strong>Aim: </strong>This study examined temporal changes in patterns of clinically treated psychiatric conditions during the first year after the 2024 Noto Peninsula Earthquake. Although post-disaster psychiatric symptoms often peak within the first year, prior studies have frequently lacked standardized phase definitions. We applied disaster-response phases defined in the Ministry of Health, Labour and Welfare manual to clarify phase-specific diagnostic trends and inform allocation of psychiatric resources.</p><p><strong>Methods: </strong>Among 869 new outpatients and 133 new inpatients recorded at Kanazawa Medical University Hospital, the tertiary medical center closest to the epicenter, between January and December 2024, we analyzed 80 first-time outpatients and 29 newly admitted inpatients reporting earthquake-related damage. Medical records were reviewed for demographics, ICD-10 primary diagnoses, disaster-related stressors, and timing of presentation categorized by disaster-response phases.</p><p><strong>Results: </strong>Psychiatric presentations were concentrated within the first month after the disaster, with secondary increases around 7 months and a modest rise at 12 months among outpatients. Most cases occurred during Stage 4 (mid-term recovery; Months 2-12). Among outpatients, neurotic, stress-related, and somatoform disorders (F4; 37.5%) and mood disorders (F3; 27.5%) were most frequent, whereas among inpatients, mood disorders (F3; 44.8%) and schizophrenia spectrum disorders (F2; 24.1%) predominated. Mood disorders were prevalent from the early phase, while F4 disorders increased later. Relocation and housing-related problems were common stressors.</p><p><strong>Conclusion: </strong>Clinically treated psychiatric conditions showed phase-dependent patterns, underscoring the need for phase-specific interventions, including early management of mood disorders, mid-term support for displacement-related stress, and long-term monitoring for symptom re-emergence.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70319"},"PeriodicalIF":0.9,"publicationDate":"2026-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe enduring anorexia nervosa with significant height increase in adulthood: A case report.","authors":"Fuyuki Michiba, Haruka Kozuki, Keima Tose, Takeru Yamauchi, Ami Keidai, Toshiya Murai, Masanori Isobe","doi":"10.1002/pcn5.70296","DOIUrl":"https://doi.org/10.1002/pcn5.70296","url":null,"abstract":"<p><strong>Background: </strong>Anorexia nervosa (AN) is a severe psychiatric disorder characterized by restrictive eating, low body weight, and distorted body image, and is often complicated by endocrine dysfunction. While hypogonadism and delayed puberty are well documented in female patients, reports in males remain scarce because of the lower prevalence of AN in this group. Hypogonadism may result in impaired pubertal development, growth arrest, and reduced testicular volume in male patients. Although weight restoration can sometimes enable catch-up growth when AN begins before puberty, the long-term potential for pubertal onset and height gain in severe enduring anorexia nervosa (SEAN) remains unclear.</p><p><strong>Case presentation: </strong>We present the case of a male patient with SEAN who showed persistent growth delay and absence of pubertal development during adolescence and early adulthood. Radiographic evaluation revealed the presence of unfused epiphyseal plates. Following sustained nutritional rehabilitation and partial weight restoration, the patient showed delayed pubertal onset accompanied by significant height gain. Endocrine assessment confirmed activation of the hypothalamic-pituitary-gonadal axis, with normalization of testosterone levels and gonadal function.</p><p><strong>Conclusion: </strong>This case demonstrates the potential for delayed puberty and substantial catch-up growth in adult male patients with SEAN, provided that epiphyseal closure has not yet occurred. Sustained nutritional rehabilitation is essential for pubertal activation. These findings highlight height gain as a clinically relevant and potentially motivational factor in treatment, while also contributing to a broader understanding of growth outcomes in chronically malnourished populations.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70296"},"PeriodicalIF":0.9,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postictal psychosis concealed during long-term video-electroencephalographic monitoring and unmasked after discharge: A case report.","authors":"Shotaro Fujiwara, Takuto Ishida, Ryotaro Higuchi, Ayumu Kocha, Yo Muraoka, Yuki Nagashima, Hiroki Kocha, Atsuo Nakagawa, Yoshiyo Oguchi","doi":"10.1002/pcn5.70321","DOIUrl":"https://doi.org/10.1002/pcn5.70321","url":null,"abstract":"<p><strong>Background: </strong>Postictal psychosis (PIP) is a serious complication that can follow seizure clusters, including those provoked during long-term video-electroencephalographic monitoring (LTVEM). Early detection and appropriate treatment of PIP are crucial to implement LTVEM safely. However, managing PIP becomes challenging when patients conceal symptoms, and psychotic symptoms are ambiguous.</p><p><strong>Case presentation: </strong>A female patient in her 30s with drug-resistant mesial temporal lobe epilepsy due to right hippocampal sclerosis underwent LTVEM at an epilepsy center. After seizure clusters occurred on hospital Days 2 and 3, she remained superficially stable apart from subtle psychotic symptoms beginning on hospital Day 4. Despite a thorough psychiatric assessment, she denied any psychotic experiences and was discharged as scheduled on hospital Day 7. Immediately after discharge, however, she displayed overt psychotic symptoms, necessitating emergency involuntary psychiatric admission. Her psychotic symptoms resolved within 16 days of psychiatric hospitalization. Upon recovery, she disclosed that she had concealed her symptoms during LTVEM because auditory command hallucinations had discouraged her from discussing the symptoms with her physicians, and her persecutory delusions, which were directed specifically toward the hospital and medical staff, had fostered a profound mistrust.</p><p><strong>Conclusion: </strong>The present case highlights a diagnostic pitfall caused by overlooking PIP occurring during LTVEM, particularly in patients in whom the psychotic content is directed against the hospital and medical staff. The absence of overt behavioral disturbances does not exclude PIP. Close multidisciplinary collaboration between epileptologists and psychiatrists is essential to ensure the patient's safety.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70321"},"PeriodicalIF":0.9,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guided internet-delivered compassion-focused therapy for women with recurrent pregnancy loss: A protocol of a randomized controlled trial.","authors":"Yuka Ito, Yuki Kawai Iwasaki, Kenichi Asano, Masatake Toshimitsu, Eisuke Sakakibara, Hinano Yumura, Yoshiaki Kanamori, Sawako Kamo, Saki K Doi, Natsu Sasaki, Kotaro Imamura, Keiichi Kumasawa, Takayuki Iriyama, Daisuke Nishi","doi":"10.1002/pcn5.70293","DOIUrl":"https://doi.org/10.1002/pcn5.70293","url":null,"abstract":"<p><strong>Aim: </strong>This randomized controlled trial aims to examine the effects of an internet-delivered compassion-focused therapy program on depressive symptoms in women with recurrent pregnancy loss.</p><p><strong>Methods: </strong>The target population will be non-pregnant women aged 18-50 years with at least two pregnancy losses who visit the recurrent pregnancy loss outpatient clinics. Participants who fulfill the eligibility criteria will be randomly assigned to either a 5-week intervention group (<i>n</i> = 55) or a waitlist control group (<i>n</i> = 55). Participants in the intervention group will be asked to complete four weekly video modules (20-25 min each), including psychoeducation, experiential exercises, and homework assignments based on compassion-focused therapy principles. The intervention incorporates psychiatrist-guided support through weekly messages encouraging participants to share insights and questions about the program. The primary outcome is depression severity measured by the Patient Health Questionnaire-9. Secondary outcomes are psychological distress, perinatal grief, self-compassion, rumination, and worry about future pregnancies. Assessments will be conducted at baseline, 5-week follow-up (post-intervention), and 13-week follow-up. Mixed model analyses will be conducted to test the effectiveness of the intervention.</p><p><strong>Results: </strong>As this is a study protocol, results are not yet available.</p><p><strong>Conclusion: </strong>If the intervention program demonstrates significant benefits, it could be offered to all women with recurrent pregnancy loss in Japan.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70293"},"PeriodicalIF":0.9,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical cortical neural activity in internet gaming disorder comorbid with autism spectrum disorder during a cue reactivity task: A magnetoencephalography study.","authors":"Faisal Budisasmita Paturungi Parawansa, Atsunori Sugimoto, Ekachaeryanti Zain, Yukina Nakazawa, Fuuta Sakuma, Kiyohiro Yoshinaga, Muhammad Dwi Wahyu, Hiroyuki Kasahara, Jun Egawa, Hiroshi Shirozu, Atsuhiko Iijima, Shuken Boku","doi":"10.1002/pcn5.70312","DOIUrl":"https://doi.org/10.1002/pcn5.70312","url":null,"abstract":"<p><strong>Aim: </strong>Significant, positive correlations between internet gaming disorder (IGD) and autism spectrum disorder (ASD) are known. Individuals with ASD are prone to problematic internet use due to addiction or restricted interests. Here, we examined cortical neural activity in individuals with IGD comorbid with ASD during a gaming-related cue reactivity task, using magnetoencephalography (MEG).</p><p><strong>Methods: </strong>MEG was used to record neural activity in right-handed male participants aged 11-20 years (11 IGD-ASD, 13 healthy controls; intelligence quotient [IQ] ≥ 80). IGD and ASD were diagnosed per DSM-5-TR criteria. During MEG recording, participants viewed gaming cues and neutral base stimuli in a cue reactivity task. Source-level cortical activity was estimated using minimum norm estimation (MNE), and statistical comparisons were performed using two-tailed nonparametric permutation tests with false discovery rate (FDR) correction.</p><p><strong>Results: </strong>In the IGD-ASD group, neural activity was significantly elevated at 137 ms in the right fusiform gyrus during gaming cues compared with the base condition (<i>p</i> = 0.000039). Between-group comparisons under cue conditions (200-270 ms) showed higher right frontal activation (<i>p</i> = 0.0028) and lower activation in left lateral occipital (<i>p</i> = 0.000092), fusiform (<i>p</i> = 0.00025), lingual (<i>p</i> = 0.0017), and parahippocampal regions (<i>p</i> = 0.000049) in the IGD-ASD group compared with controls.</p><p><strong>Conclusion: </strong>The IGD-ASD group showed increased right frontal activity and decreased left occipital, fusiform, lingual, and parahippocampal activity during exposure to the gaming cue, suggesting atypical visual and cognitive processing mechanisms in this comorbid group. Further studies comparing individuals with ASD and those with IGD-ASD, as well as by examining the neurophysiological characteristics of individuals with ASD who develop or recover from IGD, might clarify the pathology of these populations.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70312"},"PeriodicalIF":0.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of depressive symptom trajectory patterns with zuranolone: Time-series clustering of Japanese Phase 2 and Phase 3 trial data.","authors":"Masaki Kato, Takamichi Baba, Saki Nakano, Yuto Kashiwagi, Tomoko Motomiya, Nakao Iwata","doi":"10.1002/pcn5.70320","DOIUrl":"https://doi.org/10.1002/pcn5.70320","url":null,"abstract":"<p><strong>Aim: </strong>Major depressive disorder (MDD) shows varied treatment responses. Previous Phase 2 and 3 trials demonstrated the efficacy of 2-week oral zuranolone in Japanese MDD patients, but individual symptom trajectories were not analyzed. To address this gap, this study aimed to characterize patterns of depressive symptom trajectories among these patients.</p><p><strong>Methods: </strong>We conducted a pooled analysis of Phase 2/3 randomized, double-blind, placebo-controlled trials in Japanese adults with MDD. Participants received zuranolone 30 mg or placebo once daily for 14 days, with a 6-week follow-up. Patients with complete 17-item Hamilton Rating Scale for Depression (HAM-D17) data at baseline and 10 subsequent time points through Day 57 were included. Change from baseline scores underwent Dynamic Time Warping-based k-means clustering identified symptom trajectory patterns in the zuranolone group, with optimal cluster number determined by the elbow method. A Random Forest classifier then assessed scale items linked to symptom worsening trajectories.</p><p><strong>Results: </strong>Four distinct trajectories were identified. Three clusters showed varying degrees of symptom reduction during treatment, stabilizing during follow-up. The fourth cluster showed symptom reduction during the treatment period and a mean increase in HAM-D17 scores after Day 15, primarily due to worsening insomnia. Each Patient Health Questionnaire-9 (PHQ-9) score showed a similar course to the corresponding HAM-D17 scores. No notable differences were observed among clusters in baseline demographics, episode duration, or initial severity.</p><p><strong>Conclusion: </strong>This study reveals diverse symptom trajectories in zuranolone-treated patients and provides clinically relevant insights, highlighting the importance of early post-dosing monitoring-particularly of sleep symptoms-to inform clinical management and future research.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70320"},"PeriodicalIF":0.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of workplace psychosocial factors on premenstrual dysphoric disorder: A six-month prospective study on Japanese female workers.","authors":"Mako Iida, Kazuhiro Watanabe, Miho Egawa, Yuka Ito, Yoshiaki Kanamori, Rikako Tsuji, Daisuke Nishi, Natsu Sasaki","doi":"10.1002/pcn5.70313","DOIUrl":"https://doi.org/10.1002/pcn5.70313","url":null,"abstract":"<p><strong>Aim: </strong>This study examined the longitudinal associations between psychosocial factors in the workplace and the emergence of premenstrual dysphoric disorder (PMDD) symptoms among Japanese female workers, with a particular focus on psychological distress as a potential moderator.</p><p><strong>Methods: </strong>We conducted a 6-month follow-up of 2000 full-time Japanese female workers aged 20-39 without PMDD symptoms at baseline. PMDD symptoms were assessed at follow-up using a validated PMDD scale. Psychosocial factors in the workplace (job demands, job control, supervisor and coworker support, and workplace rewards) were measured at baseline using the New Brief Job Stress Questionnaire. Psychological distress was assessed using the Kessler 6 psychological distress scale (K6), and participants were stratified by K6 scores (K6 < 5 and K6 ≥ 5). Logistic regression analyses were performed.</p><p><strong>Results: </strong>Of the eligible participants, 1064 completed both surveys (response rate: 61.6%). In the adjusted models, high job control was associated with the emergence of PMDD symptoms among all participants (odds ratio [OR] = 1.26, <i>p</i> = 0.025) and those with high psychological distress (OR = 1.37, <i>p</i> = 0.011). Job stability was negatively associated with the emergence of PMDD symptoms among participants with high psychological distress (OR = 0.48, <i>p</i> = 0.010). No significant associations were found among those with low psychological distress.</p><p><strong>Conclusion: </strong>Job stability was a protective factor for the emergence of PMDD symptoms among female workers with high psychological distress, while job control may act as an enhancing factor in the overall sample and among those with high psychological distress. Ensuring job stability might be a measure to prevent PMDD symptoms, especially for female workers with high psychological distress.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70313"},"PeriodicalIF":0.9,"publicationDate":"2026-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12967474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of young carers' experiences on their mental health in emerging adulthood: Evaluation from a psychiatric perspective.","authors":"Miki Ono, Yuuka Matsuzaki, Minori Sato, Jun Tsuchida, Akiyoshi Shimura, Yu Tamada, Chihiro Morishita, Jiro Masuya, Masayuki Kikkawa, Takeshi Inoue","doi":"10.1002/pcn5.70316","DOIUrl":"https://doi.org/10.1002/pcn5.70316","url":null,"abstract":"<p><strong>Aim: </strong>Previous research has primarily explored the negative impacts of caregiving on young carers (YCs)' mental health during childhood and adolescence, with limited focus on emerging adulthood. In particular, quantitative evidence on the development of depression in YCs in emerging adulthood is limited, especially regarding its persistence after caregiving ends. To address this, we aimed to assess the mental health of emerging adults with YC experience by categorizing them into past YCs (pYCs) who no longer provide care and those who continue to provide care (current young adult carer/past YCs, cYAC/pYCs) alongside a non-YCs control group. We also aimed to identify factors contributing to depressive symptoms in these groups, focusing on caregiving-related environmental factors during childhood and adolescence.</p><p><strong>Methods: </strong>Participants aged 18-25 were recruited online and divided into three groups. Demographic information, depressive/anxiety symptoms, well-being, and peer victimization were assessed, and binomial logistic regression analysis was performed to examine the factors contributing to depressive symptoms.</p><p><strong>Results: </strong>A total of 162 cYAC/pYCs, 161 pYCs, and 534 non-YCs were analyzed. Both the cYAC/pYCs and pYCs groups had higher levels of depressive and anxiety symptoms than the non-YCs group, with no significant differences between cYAC/pYCs and pYCs. Multivariable analysis demonstrated that female sex, taking care of their own caregiver, solo family caregiving, and experiencing peer victimization were significant predictors of depressive symptoms.</p><p><strong>Conclusion: </strong>Being a YC has lasting impacts on mental health and the risk of depressive symptoms, emphasizing the need for targeted interventions to support this vulnerable population.</p>","PeriodicalId":74405,"journal":{"name":"PCN reports : psychiatry and clinical neurosciences","volume":"5 1","pages":"e70316"},"PeriodicalIF":0.9,"publicationDate":"2026-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12967540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}