Npj mental health research最新文献

Transition and dynamic reconfiguration in late-life depression based on hidden Markov model. 基于隐马尔可夫模型的老年抑郁症的转变与动态重构。

Npj mental health research Pub Date : 2025-05-27 DOI: 10.1038/s44184-025-00137-7

Hairong Xiao, Caili Kang, Wei Zhao, Shuixia Guo

引用次数: 0

Mental health impacts of particulate matter exposure and non-optimal temperature among rural and urban children in eastern China. 中国东部城乡儿童颗粒物暴露和非最适温度对心理健康的影响

Npj mental health research Pub Date : 2025-05-19 DOI: 10.1038/s44184-025-00132-y

Yangyang Wu, Jing Wei, Biran Cheng, Hong Sun, Yidong Zhou, Chen Li, Peng Wang, Hao Zhang, Yiyi Wang, Lei Huang, Kai Chen

{"title":"Mental health impacts of particulate matter exposure and non-optimal temperature among rural and urban children in eastern China.","authors":"Yangyang Wu, Jing Wei, Biran Cheng, Hong Sun, Yidong Zhou, Chen Li, Peng Wang, Hao Zhang, Yiyi Wang, Lei Huang, Kai Chen","doi":"10.1038/s44184-025-00132-y","DOIUrl":"10.1038/s44184-025-00132-y","url":null,"abstract":"Over 100 million children worldwide suffer from mental distress, with incidence rates steadily increasing. However, the combined impacts of air pollution and non-optimal temperature on schoolchildren's mental health, as well as the disparities across urban and rural schools and between genders, remain insufficiently explored. Utilizing 95,658 mental distress records from school children in eastern China, we developed nine composite exposure scenarios to evaluate the mental health impacts of short-term (0-14 days) exposure to particulate matter (PM) air pollution (i.e., PM1, PM2.5, PM10), average temperature, and temperature variability (including both intra-day and inter-day temperature fluctuations). We found that children's mental distress was significantly associated with PM pollution, particularly in urban schools, with rising risk trends and intensified hazards for finer particles (PM10 < PM2.5 < PM1). For each 10 μg/m³ increase, the relative risks of mental distress absenteeism for PM1, PM2.5, and PM10 were 1.017, 1.011, and 1.008, respectively. Polluted days coupled with warming temperature >10 °C and large intra-day (>10 °C) and inter-day fluctuations (<-2.5 or >0 °C) consistently exhibited higher and increasing risks, with relative risks ranging from 1.031 to 1.534 (p < 0.05). Girls, constituting 61.4% of the cases examined, exhibited greater vulnerability than boys, with higher threats and rising trends across all scenarios. Among the affected children, 77.9% didn't receive medical assistance. Given the global warming trend, it's crucial to address the combined impacts of extreme weather and PM pollution on schoolchildren's mental health, particularly for girls and in rapidly urbanizing areas.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Randomized trial testing a self-guided digital mental health intervention teaching calming skills for Ukrainian children. 随机试验测试一种自我引导的数字心理健康干预，为乌克兰儿童教授镇静技巧。

Npj mental health research Pub Date : 2025-05-16 DOI: 10.1038/s44184-025-00134-w

Joshua S Steinberg, Jingxuan Sun, Katherine E Venturo-Conerly, Gauri Sood, Patrick Mair, Oksana Davydenko, Robert Porzak, Dennis Ougrin, John R Weisz

{"title":"Randomized trial testing a self-guided digital mental health intervention teaching calming skills for Ukrainian children.","authors":"Joshua S Steinberg, Jingxuan Sun, Katherine E Venturo-Conerly, Gauri Sood, Patrick Mair, Oksana Davydenko, Robert Porzak, Dennis Ougrin, John R Weisz","doi":"10.1038/s44184-025-00134-w","DOIUrl":"10.1038/s44184-025-00134-w","url":null,"abstract":"Ukraine's war-exposed youth face a myriad of barriers to receiving mental health services, perhaps most notably a dearth of mental health professionals. Experts recommend evaluating digital mental health interventions (DMHIs), which require minimal clinician support. Based on the content of empirically supported treatments for war-exposed youth (e.g., Teaching Recovery Techniques), one strategy that might be useful is self-calming (e.g., paced breathing, progressive muscle relaxation). In this pre-registered randomized controlled trial (ClinicalTrials.gov Record: NCT06217705 ; first submitted January 12, 2024), we assessed the acceptability, utility, and clinical efficacy of one such DMHI (Project Calm) relative to a usual schoolwork control among a sample of Ukrainian students in grades 4-11. We analyzed outcomes for the full sample and subsamples with elevated symptoms at baseline. Although Calm was perceived favorably, there were no significant between-group differences in the full sample (N = 626); differences in subsample analyses demonstrated that while internalizing, externalizing, and trauma symptoms held steady for the Calm group, control participants' symptoms reduced. We generated potential explanations for these results (e.g., interference with youths' natural coping skills or fear extinction) through a focus group with school staff. Given that we found no evidence that calming skills taught via DMHI are effective for Ukrainian youth, we suggest that researchers test other strategies delivered by DMHI and that calming skills continue to be taught in provider-guided formats.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subtyping first-episode psychosis based on longitudinal symptom trajectories using machine learning. 基于使用机器学习的纵向症状轨迹对首发精神病进行分型。

Npj mental health research Pub Date : 2025-05-15 DOI: 10.1038/s44184-025-00129-7

Yanan Liu, Sara Jalali, Ridha Joober, Martin Lepage, Srividya Iyer, Jai Shah, David Benrimoh

{"title":"Subtyping first-episode psychosis based on longitudinal symptom trajectories using machine learning.","authors":"Yanan Liu, Sara Jalali, Ridha Joober, Martin Lepage, Srividya Iyer, Jai Shah, David Benrimoh","doi":"10.1038/s44184-025-00129-7","DOIUrl":"10.1038/s44184-025-00129-7","url":null,"abstract":"Clinical course after first episode psychosis (FEP) is heterogeneous. Subgrouping and predicting longitudinal symptom trajectories after FEP may help develop personalized treatment approaches. We utilized k-means clustering to identify clusters of 411 FEP patients based on longitudinal positive and negative symptoms. Three clusters were identified. Cluster 1 exhibits lower positive and negative symptoms (LS), lower antipsychotic dose, and relatively higher affective psychosis; Cluster 2 shows lower positive symptoms, persistent negative symptoms (LPPN), and intermediate antipsychotic doses; Cluster 3 presents persistently high levels of both positive and negative symptoms (PPNS), and higher antipsychotic doses. We predicted cluster membership (AUC of 0.74) using ridge logistic regression on baseline data. Key predictors included lower levels of apathy, affective flattening, and anhedonia/asociality in the LS cluster, compared to the LPPN cluster. Hallucination severity, positive thought disorder and manic hostility predicted PPNS. These results help parse the FEP trajectory heterogeneity and may facilitate the development of personalized treatments.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"18"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Canonical and non-canonical roles of oligodendrocyte precursor cells in mental disorders. 少突胶质前体细胞在精神障碍中的典型和非典型作用。

Npj mental health research Pub Date : 2025-05-15 DOI: 10.1038/s44184-025-00133-x

Giulia Poggi, Giulia Treccani, Martina von der Bey, Arnaud Tanti, Michael J Schmeisser, Marianne Müller

引用次数: 0

Electrocardiography-derived autonomic profiles in depression and suicide risk with insights from the UK Biobank. 来自英国生物银行的见解在抑郁症和自杀风险中的心电图衍生的自主神经谱。

Npj mental health research Pub Date : 2025-05-14 DOI: 10.1038/s44184-025-00130-0

Samantha Weber, Mario Müller, Golo Kronenberg, Erich Seifritz, Vladeta Ajdacic-Gross, Sebastian Olbrich

{"title":"Electrocardiography-derived autonomic profiles in depression and suicide risk with insights from the UK Biobank.","authors":"Samantha Weber, Mario Müller, Golo Kronenberg, Erich Seifritz, Vladeta Ajdacic-Gross, Sebastian Olbrich","doi":"10.1038/s44184-025-00130-0","DOIUrl":"https://doi.org/10.1038/s44184-025-00130-0","url":null,"abstract":"The role of the autonomic nervous system (ANS) in depression and suicidality is multifaceted. This study examined whether distinct electrocardiography based ANS profiles exist, associated with a lifetime/recent at-risk cohort or a resilient group. Using data from 15,768 participants from the UK Biobank, four unique ANS activity patterns related to heart rate variability (HRV) measures were identified. Two specific clusters, both with low HRV, showed different risks: one characterized by high relative sympathetic tonus and lower breathing rate, indicated higher resilience with less likely depressive symptoms and suicidal thoughts whereas another cluster with dominant relative parasympathetic activity and high breathing rate, aligned with greater depression and suicide attempt prevalence, potentially representing a high-risk cluster. Resilience to depression might be defined by different psychophysiological entities and coping strategies, where the resilient cluster might be characterized by cognitive coping strategies, and increased susceptibility might be linked to more rigid maladaptive coping strategies.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the impact of AI on physician decision-making for mental health treatment in primary care. 评估人工智能对初级保健中心理健康治疗医生决策的影响。

Npj mental health research Pub Date : 2025-05-10 DOI: 10.1038/s44184-025-00124-y

Katie Ryan, Hyun-Joon Yang, Bohye Kim, Jane Paik Kim

引用次数: 0

Examining measurement discrepancies in adolescent screen media activity with insights from the ABCD study. 用ABCD研究的见解检查青少年屏幕媒体活动的测量差异。

Npj mental health research Pub Date : 2025-05-10 DOI: 10.1038/s44184-025-00131-z

Yihong Zhao, Xuewei Han, Kara S Bagot, Susan F Tapert, Marc N Potenza, Martin P Paulus

{"title":"Examining measurement discrepancies in adolescent screen media activity with insights from the ABCD study.","authors":"Yihong Zhao, Xuewei Han, Kara S Bagot, Susan F Tapert, Marc N Potenza, Martin P Paulus","doi":"10.1038/s44184-025-00131-z","DOIUrl":"https://doi.org/10.1038/s44184-025-00131-z","url":null,"abstract":"Concerns about the accuracy of self-reported screen time persist due to discrepancies with objective measures. This study compared passive smartphone tracking via the \"Effortless Assessment of Risk States'' (EARS) app with self-reported screen time from 495 adolescents. Based on self-reports, 94.26% of social media use occurred on smartphones. EARS-recorded social media use was higher (1.64 ± 1.93 h) than past-year self-report (1.44 ± 1.97 h; p = 0.037) but similar to post-sensing self-report (1.63 ± 1.93 h; p = 0.835). Higher picture vocabulary scores were associated with lower odds of under-reporting social media use (OR = 0.96, 95% CI: 0.93-0.99). Both self-reported (β = 0.06, 95% CI: 0.01-0.11) and EARS (β = 0.07, 95% CI: 0.03-0.12) measures correlated with externalizing symptoms. They were also correlated with social media addiction (self-reported:β = 0.15, 95% CI: 0.10-0.20; EARS:β = 0.06, 95% CI: 0.01-0.11). However, past-year self-report uniquely correlated with internalizing symptoms (β = 0.05, 95% CI: 0.01-0.09) and video game addiction (β = 0.05, 95% CI: 0.01-0.10). These findings highlight the value of integrating self-report and objective measures in screen media use research.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When the glass is half full: early life experiences and adult optimism in 22 countries. 当杯子是半满的时候：22个国家的早期生活经历和成人乐观主义。

Npj mental health research Pub Date : 2025-04-30 DOI: 10.1038/s44184-024-00109-3

Ying Chen, Laura D Kubzansky, Eric S Kim, Hayami Koga, Koichiro Shiba, R Noah Padgett, Renae Wilkinson, Byron R Johnson, Tyler J VanderWeele

{"title":"When the glass is half full: early life experiences and adult optimism in 22 countries.","authors":"Ying Chen, Laura D Kubzansky, Eric S Kim, Hayami Koga, Koichiro Shiba, R Noah Padgett, Renae Wilkinson, Byron R Johnson, Tyler J VanderWeele","doi":"10.1038/s44184-024-00109-3","DOIUrl":"https://doi.org/10.1038/s44184-024-00109-3","url":null,"abstract":"Little is known about early-life experiences that may lead to higher optimism levels in adulthood. Using data from 202,898 adults in 22 countries, we evaluated childhood candidate antecedents of optimism. We examined the associations between retrospectively reported childhood experiences and adult optimism levels in each country separately, and cross-nationally by pooling results across countries. Our pooled results suggest that higher adult optimism levels were associated with childhood experiences of having positive relationships with both parents, higher subjective financial status, better childhood self-rated health, frequent religious service attendance, an earlier year of birth, and being female. Conversely, lower adult optimism was associated with childhood experiences of parental divorce, abuse, financial hardship, and feeling like an outsider in the family. However, country-specific analyses showed substantial between-country variations in these associations, suggesting diverse societal influences. This study provides valuable insights into the association between early-life experiences and adult optimism levels across national contexts.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying childhood correlates of adult purpose and meaning across 22 countries (Global Flourishing Study). 在22个国家中确定童年与成人目标和意义的相关性（全球繁荣研究）。

Npj mental health research Pub Date : 2025-04-30 DOI: 10.1038/s44184-025-00127-9

Eric S Kim, Matt Bradshaw, R Noah Padgett, Ying Chen, Koichiro Shiba, James L Ritchie-Dunham, Brendan W Case, Byron R Johnson, Tyler J VanderWeele

{"title":"Identifying childhood correlates of adult purpose and meaning across 22 countries (Global Flourishing Study).","authors":"Eric S Kim, Matt Bradshaw, R Noah Padgett, Ying Chen, Koichiro Shiba, James L Ritchie-Dunham, Brendan W Case, Byron R Johnson, Tyler J VanderWeele","doi":"10.1038/s44184-025-00127-9","DOIUrl":"https://doi.org/10.1038/s44184-025-00127-9","url":null,"abstract":"How might we cultivate a life imbued with purpose and meaning? Though common experience indicates purpose and meaning are inherently important, empirical evidence confirms they are also linked to improved health/well-being. However, childhood antecedents of purpose and meaning in adulthood are understudied. We analyzed nationally representative data from 22 countries in the Global Flourishing Study (N = 202,898) and evaluated whether 11 aspects of a child's upbringing correlate with purpose and meaning in adulthood, and if these associations vary by country. Some childhood factors were associated with increased purpose and meaning, including: good health, good relationship with parents, economic stability, regular religious service attendance, being female, and older birth cohorts. Childhood factors associated with decreased purpose and meaning included: abuse, feeling alienated, poor health, economic hardship, and loss of a parent. These findings may inform the development of programs designed to foster purpose and meaning that are globally adaptable and locally nuanced.","PeriodicalId":74321,"journal":{"name":"Npj mental health research","volume":"4 1","pages":"14"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0