Christopher Hurst, Lorelle Dismore, Antoneta Granic, Ellen Tullo, Jane M Noble, Susan J Hillman, Miles D Witham, Avan A Sayer, Richard M Dodds, Sian M Robinson
{"title":"Feasibility of engaging older adults living with multiple long-term conditions, frailty, and a recent deterioration in health in a study of lifestyle: protocol for the LiLL-OPM study.","authors":"Christopher Hurst, Lorelle Dismore, Antoneta Granic, Ellen Tullo, Jane M Noble, Susan J Hillman, Miles D Witham, Avan A Sayer, Richard M Dodds, Sian M Robinson","doi":"10.22540/JFSF-08-127","DOIUrl":"https://doi.org/10.22540/JFSF-08-127","url":null,"abstract":"<p><p>Community-dwelling older adults living with multiple long-term conditions (MLTC), frailty and a recent deterioration in health are underserved by research. This results in a limited evidence base for their care, including the potential benefits of lifestyle interventions such as structured exercise. The aims of the LiLL-OPM (Lifestyle in Later Life - Older People's Medicine) study are to determine if it is feasible to carry out a research project with these patients, describe their health and lifestyle, their attitudes to engaging in exercise and their experiences of taking part in the research. Older adults who are attending an Older People's Medicine Day Unit service in Newcastle, UK, and their informal carers will be invited to take part. The study will use mixed methods with semi-structured interviews and a health and lifestyle questionnaire, carried out in a way that is most convenient to participants, including in their own homes and with a flexible schedule of study visits. The findings from the feasibility study will provide invaluable data on how to design research, including the most suitable approaches to recruitment and data collection. This will improve the inclusion in research of older adults living with MLTC, frailty and a recent deterioration in health.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"127-135"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/bd/JFSF-8-127.PMC10233323.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9584098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christos Nikitas, Dimitris Kikidis, Athanasios Pardalis, Michalis Tsoukatos, Sofia Papadopoulou, Athanasios Bibas, Doris E Bamiou
{"title":"Head mounted display effect on vestibular rehabilitation exercises performance.","authors":"Christos Nikitas, Dimitris Kikidis, Athanasios Pardalis, Michalis Tsoukatos, Sofia Papadopoulou, Athanasios Bibas, Doris E Bamiou","doi":"10.22540/JFSF-08-066","DOIUrl":"https://doi.org/10.22540/JFSF-08-066","url":null,"abstract":"<p><strong>Objectives: </strong>Vestibular rehabilitation clinical guidelines document the additional benefit offered by the Mixed Reality environments in the reduction of symptoms and the improvement of balance in peripheral vestibular hypofunction. The HOLOBalance platform offers vestibular rehabilitation exercises, in an Augmented Reality (AR) environment, projecting them using a low- cost Head Mounted Display. The effect of the AR equipment on the performance in three of the commonest vestibular rehabilitation exercises is investigated in this pilot study.</p><p><strong>Methods: </strong>Twenty-five healthy adults (12/25 women) participated, executing the predetermined exercises with or without the use of the AR equipment.</p><p><strong>Results: </strong>Statistically significant difference was obtained only in the frequency of head movements in the yaw plane during the execution of a vestibular adaptation exercise by healthy adults (0.97 Hz; 95% CI=(0.56, 1.39), p<0.001). In terms of difficulty in exercise execution, the use of the equipment led to statistically significant differences at the vestibular-oculomotor adaptation exercise in the pitch plane (OR=3.64, 95% CI (-0.22, 7.50), p=0.049), and in the standing exercise (OR=28.28. 95% CI (23.6, 32.96), p=0.0001).</p><p><strong>Conclusion: </strong>Τhe use of AR equipment in vestibular rehabilitation protocols should be adapted to the clinicians' needs.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"66-73"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ce/d3/JFSF-8-066.PMC10233325.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9584099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frailty as a risk-stratification tool in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).","authors":"Aalam Sohal, Hunza Chaudhry, Isha Kohli, Kirti Arora, Jay Patel, Nimrat Dhillon, Ishandeep Singh, Dino Dukovic, Marina Roytman","doi":"10.22540/JFSF-08-083","DOIUrl":"https://doi.org/10.22540/JFSF-08-083","url":null,"abstract":"<p><strong>Objectives: </strong>The concept of frailty has gained importance, especially in patients with liver disease. Our study systematically investigated the effect of frailty on post-procedural outcomes in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).</p><p><strong>Methods: </strong>We used National Inpatient Sample(NIS) 2016-2019 data to identify patients who underwent TIPS. Hospital frailty risk score (HFRS) was used to classify patients as frail (HFRS>=5) and non-frail (HFRS<5). The relationship between frailty and outcomes such as death, post-procedural shock, non-home discharge, length of stay (LOS), post-procedural LOS, and total hospitalization charges (THC) was assessed.</p><p><strong>Results: </strong>A total of 13,700 patients underwent TIPS during 2016-2019. Of them, 5,995 (43.76%) patients were frail, while 7,705 (56.24%) were non-frail. There were no significant differences between the two groups based on age, gender, race, insurance, and income. Frail patients had higher mortality (15.18% vs. 2.07%, p<0.001), a higher incidence of non-home discharge (53.38% vs. 19.08%, p<0.001), a longer overall LOS (12.5 days vs. 3.35,p<0.001), longer post-procedural stay (8.2 days vs. 3.4 days, p<0.001), and higher THC ($240,746.7 vs. $121,763.1, p<0.001) compared to the non-frail patients. On multivariate analysis, frail patients had a statistically significant higher risk of mortality (aOR-3.22, 95% CI-1.98- 5.00, p<0.001).</p><p><strong>Conclusion: </strong>Frailty assessment can be beneficial in risk stratification in patients undergoing TIPS.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/c7/JFSF-8-083.PMC10233326.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of an exercise-based rehabilitation programme in functional recovery and prevention of secondary falls after a hip fracture in older adults: A systematic review.","authors":"Anna Pantouvaki, Evridiki Patelarou, Grigorios Kastanis, Kalliopi Alpantaki, Michail Zografakis Sfakianakis","doi":"10.22540/JFSF-08-118","DOIUrl":"https://doi.org/10.22540/JFSF-08-118","url":null,"abstract":"<p><p>We performed a systematic review to evaluate whether an exercise-based intervention programme, for older people with a hip fracture, is effective in functional recovery and in preventing secondary fall-related injuries. This systematic review was conducted according to Cochrane review guidelines and based on the PRISMA statement. Six electronic databases (Medline, PubMed, Cochrane Library, CIHNAL, Embase, Google Scholar) from 2010 to 31 December 2021 were searched for randomised controlled trials (RCTs) of functional recovery or fall prevention exercises after a hip fracture surgery in older people (≥65 years). Thirty-four references were identified initially, however, only 8 studies (1617 patients) met the eligibility criteria. Despite the heterogeneity of the onset, duration and of the characteristics of exercise-based intervention, as well as the type of setting it was delivered in, there was evidence that an exercise-based rehabilitation programme improved physical function and gait ability. There was no evidence about preventing a secondary fall after a hip fracture. In conclusion, an exercise-based intervention programme can generally improve functional recovery after a hip fracture. It remains uncertain if it affects the prevention of a secondary fall over a 1-year follow-up period.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"118-126"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f6/8d/JFSF-8-118.PMC10233327.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9584096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pavlos Angelopoulos, Maria Tsekoura, Konstantinos Mylonas, Grigorios Tsigkas, Evdokia Billis, Elias Tsepis, Konstantinos Fousekis
{"title":"The effectiveness of blood flow restriction training in cardiovascular disease patients: A scoping review.","authors":"Pavlos Angelopoulos, Maria Tsekoura, Konstantinos Mylonas, Grigorios Tsigkas, Evdokia Billis, Elias Tsepis, Konstantinos Fousekis","doi":"10.22540/JFSF-08-107","DOIUrl":"https://doi.org/10.22540/JFSF-08-107","url":null,"abstract":"<p><p>Therapeutic exercise is integral to the comprehensive rehabilitation of patients with cardiovascular disease and, as such, is recommended by the American Heart Association as a valuable and effective treatment method for such patients. The type of exercise applied to these patients is aerobic and resistance exercise with mild intensities and loads to avoid overloading the cardiovascular system. Blood flow restriction exercise is a novel exercise modality in clinical settings that has in many studies a similar effect on muscle hypertrophy, strength, and cardiovascular response to training at a 70% strength level without blood flow restriction. Since this exercise mode does not require high-intensity loads, it can be a safe method for improving muscle strength, cardiovascular endurance, and functionality in cardiovascular patients. Given that, the objective of this review is to assess and summarize existing evidence for the use of blood flow restriction in cardiovascular patients. A scoping review of existing clinical trials was conducted. Eleven studies were examined that suggested the use of blood flow restrictions in cardiovascular patients to achieve improvements in muscle strength, functionality, and cardiovascular parameters such as blood pressure decrease.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"107-117"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/76/00/JFSF-8-107.PMC10233322.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9584094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Escribà-Salvans, Sandra Rierola-Fochs, Pau Farrés-Godayol, Miriam Molas-Tuneu, Dyego Leandro Bezerra de Souza, Dawn A Skelton, Ester Goutan-Roura, Eduard Minobes-Molina, Javier Jerez-Roig
{"title":"Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: A hypothesis-generating observational study.","authors":"Anna Escribà-Salvans, Sandra Rierola-Fochs, Pau Farrés-Godayol, Miriam Molas-Tuneu, Dyego Leandro Bezerra de Souza, Dawn A Skelton, Ester Goutan-Roura, Eduard Minobes-Molina, Javier Jerez-Roig","doi":"10.22540/JFSF-08-074","DOIUrl":"https://doi.org/10.22540/JFSF-08-074","url":null,"abstract":"Background. COVID-19 pandemic has had a major impact on society, including on residents of nursing homes (NH), who have a higher risk of complications and mortality due their physical and intellectual disabilities. Aim. To identify which risk factors associated with developing COVID-19 infection with symptoms in institutionalized older people. Methods. A 1-year longitudinal multicenter study was conducted in 5 NH during the period December 2019 to March 2021. The inclusion criteria used were residents aged 65 years or over, living in the NH permanently, with a diagnostic test for COVID-19 confirmed by reverse transcription polymerase chain reaction and/or serological test. The main variable was symptomatic COVID-19, with at least one of the following symptoms (fever, respiratory difficulties, cough, diarrhea, sudden urinary incontinence and disorientation or delirium). Three assessments were performed: baseline, six and twelve months follow-up. Descriptive and bivariate analysis (calculating relative risk-RR) were performed, considering a 95% confidence level and a statistically significant p <0.05. Results. Of the total sample of 78 individuals who tested positive for COVID-19, mean age 84.6 years (SD=7.8), 62 (79.5%) were female; 40 (51.3%) participants presented with COVID-19 symptoms. Living in a private NH (RR=3.6, 95% CI [1.2-11.0], p =0.023) and having suffered a stroke (RR=4.1, 95% CI [1.1-14.7], p =0.033) were positively associated with developing COVID-19 infection with symptoms. Conclusions. Having suffered a stroke and living permanently in a private health care facility were positively associated with symptomatic COVID-19 in this sample of institutionalized older people.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"74-82"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/a7/JFSF-8-074.PMC10233324.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Women's perceptions or experiences of physical activity and exercise interventions to improve bone health: a systematic review.","authors":"C Ryanne Plesh, Rebecca A Withers, Dawn A Skelton","doi":"10.22540/JFSF-08-094","DOIUrl":"https://doi.org/10.22540/JFSF-08-094","url":null,"abstract":"<p><p>Exercise is an important intervention to maintain bone health in women with osteopenia and osteoporosis. This systematic review aims to gain insight into the experiences or perceptions females have toward bone health interventions, to promote uptake and adherence. Four electronic databases were searched: MEDLINE, CINAHL, PubMed and PsycInfo. Inclusion Criteria: Qualitative studies examining perceptions or views of women to physical activity or exercise interventions aimed at improving bone health. 1,406 papers were identified. After screening, data were extracted from 2 studies considering experiences and 2 papers presenting perceptions of exercise for bone health. All studies scored >8 out of 10 on the CASP Quality Tool. Older women perceived barriers such as safety and advice, and facilitators of tangible results and feedback within supervised group sessions. Older womens' experiences of a digitally delivered exercise intervention included social interactions and voice reminders, with barriers of lack of feedback and knowledge. Younger women expressed enablers as feeling the benefits and physical literacy, and barriers of previous experience participating in tedious exercise. Supervised sessions, with different intensity levels and variety, offering feedback to promote confidence, are valuable to uptake and adherence in both younger and older females.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"94-106"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fe/e0/JFSF-8-094.PMC10233328.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua L Bennett, Maha Egail, Amy E Anderson, Richard Dodds, Catherine Feeney, Gráinne S Gorman, Arthur G Pratt, Avan A Sayer, Kieren G Hollingsworth, John D Isaacs
{"title":"The Rheumatoid Arthritis and MUScle (RAMUS) Study: Protocol for an observational single-arm study of skeletal muscle in patients with rheumatoid arthritis receiving tofacitinib.","authors":"Joshua L Bennett, Maha Egail, Amy E Anderson, Richard Dodds, Catherine Feeney, Gráinne S Gorman, Arthur G Pratt, Avan A Sayer, Kieren G Hollingsworth, John D Isaacs","doi":"10.22540/JFSF-08-053","DOIUrl":"https://doi.org/10.22540/JFSF-08-053","url":null,"abstract":"<p><p>People with rheumatoid arthritis (RA) are disproportionately affected by sarcopenia, the generalised loss of muscle strength and mass, consequently facing an increased risk of falls, functional decline and death. Currently, there are no approved pharmacological treatments for sarcopenia. RA patients who start tofacitinib (a Janus kinase inhibitor) develop small increases in serum creatinine that are not explained by renal function changes and could reflect sarcopenia improvement. The RAMUS Study is a proof of concept, single-arm observational study in which patients with RA who commence tofacitinib according to routine care will be offered participation according to eligibility criteria. Participants will undergo lower limb quantitative magnetic resonance imaging, whole-body dual energy x-ray absorptiometry, joint examination, muscle function testing and blood tests at three time points: prior to starting tofacitinib and 1 and 6 months afterwards. Muscle biopsy will be performed before and 6 months after starting tofacitinib. The primary outcome will be lower limb muscle volume changes following treatment initiation. The RAMUS Study will investigate whether muscle health improves following tofacitinib treatment for RA. Identifying a potential pharmacological treatment for sarcopenia could have important implications for individuals with RA and for older people in general. ISRCTN registry ID: 13364395.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"53-59"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/eb/JFSF-8-053.PMC9975967.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10837185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sarcopenia in Rheumatoid arthritis. A narrative review.","authors":"Dimitra Moschou, Michail Krikelis, Christos Georgakopoulos, Evangelia Mole, Efstathios Chronopoulos, Symeon Tournis, Clio Mavragani, Konstantinos Makris, Ismene Dontas, Susana Gazi","doi":"10.22540/JFSF-08-044","DOIUrl":"https://doi.org/10.22540/JFSF-08-044","url":null,"abstract":"<p><p>Sarcopenia was recently identified as an entity in the ICD-10 classification of October 2016. According to the recommendation of the European Working Group on Sarcopenia in Older People (EWGSOP2), sarcopenia is defined as low muscle strength and low muscle mass, while physical performance is used to categorize the severity of sarcopenia. In recent years, sarcopenia has become increasingly common in younger patients with autoimmune diseases such as Rheumatoid arthritis (RA). Due to the chronic inflammation caused by RA, patients have reduced physical activity, immobility, stiffness, and joint destruction and all of that lead to the loss of muscle mass, muscle strength, disability and significantly lowering the patients' quality of life. This article is a narrative review about sarcopenia in RA, with a special focus in its pathogenesis and management.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"44-52"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/06/50/JFSF-8-044.PMC9975974.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Christakou, Christina Bouzineki, Marousa Pavlou, George Stranjalis, Vasiliki Sakellari
{"title":"The effectiveness of mental imagery on motor, cognitive and emotional status of older people with early-stage dementia: A study protocol.","authors":"Anna Christakou, Christina Bouzineki, Marousa Pavlou, George Stranjalis, Vasiliki Sakellari","doi":"10.22540/JFSF-08-060","DOIUrl":"https://doi.org/10.22540/JFSF-08-060","url":null,"abstract":"<p><p>Dementia involves the loss of cognitive abilities and represents a decline from the prior level of function which impairs functional abilities in day-to-day life. No previous experimental research has been done to assess mental imagery (MI) effectiveness in the motor, cognitive and emotional status of individuals with early-stage dementia. One hundred and forty older individuals with early-stage dementia from the Day Care Centre of the Alzheimer Association in Athens will take part in this study. The sample will be randomly divided into three groups: MI and physical exercise (intervention group), only physical exercise (1<sup>st</sup> control group), and neither MI nor physical exercise (2<sup>nd</sup> control group). Assessment will be obtained one week prior to the program, in the middle of the program (6<sup>th</sup> week of the intervention program) and after the end of the program (13<sup>th</sup> week of the intervention program). Participants of the intervention group will perform a 30-minute MI programme after the end of every physiotherapy session. Reliable and valid instruments will be used to assess the primary outcomes, i.e., balance and functional status as well as the secondary outcomes i.e., cognitive ability, emotional state and quality of life. The two-way Mixed ANOVA with factors 'intervention' (between groups) and 'time' (within group) will be used as a statistical analysis. Approvals of clinical trial protocol: a) UNIWA Research Committee study protocol approval: 93292 - 26/10/2021. b) ClinicalTrials.gov: ID NCT05232526.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"60-65"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/01/JFSF-8-060.PMC9975972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9410799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}