Journal of frailty, sarcopenia and falls最新文献

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About Falls Efficacy: A commentary on "World guidelines for falls prevention and management for older adults: a global initiative". 关于跌倒功效:对“老年人跌倒预防和管理世界指南:一项全球倡议”的评论。
Journal of frailty, sarcopenia and falls Pub Date : 2024-12-01 DOI: 10.22540/JFSF-09-281
Shawn Leng Hsien Soh, Christopher McCrum, Yoshi Okubo, Melanie Farlie, Sze-Ee Soh, Maw Pin Tan, Christopher Tsung Chien Lien, Dawn A Skelton
{"title":"About Falls Efficacy: A commentary on \"World guidelines for falls prevention and management for older adults: a global initiative\".","authors":"Shawn Leng Hsien Soh, Christopher McCrum, Yoshi Okubo, Melanie Farlie, Sze-Ee Soh, Maw Pin Tan, Christopher Tsung Chien Lien, Dawn A Skelton","doi":"10.22540/JFSF-09-281","DOIUrl":"10.22540/JFSF-09-281","url":null,"abstract":"","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 4","pages":"281-285"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Physical Therapy 4-Month In-Home Dynamic Standing Protocol Maintains Physical Therapy Gains and Improves Mobility, Balance Confidence, Fear of Falling and Quality of Life in Parkinson's Disease: A Randomized Controlled Examiner-Blinded Feasibility Clinical Trial. 物理治疗后4个月在家动态站立方案维持物理治疗成果,改善帕金森病患者的活动能力、平衡信心、对跌倒的恐惧和生活质量:一项随机对照检查-盲法可行性临床试验
Journal of frailty, sarcopenia and falls Pub Date : 2024-12-01 DOI: 10.22540/JFSF-09-267
Miriam van Emde Boas, Chatkaew Pongmala, Abigail M Biddix, Alexis Griggs, Austin T Luker, Giulia Carli, Uros Marusic, Nicolaas I Bohnen
{"title":"Post-Physical Therapy 4-Month In-Home Dynamic Standing Protocol Maintains Physical Therapy Gains and Improves Mobility, Balance Confidence, Fear of Falling and Quality of Life in Parkinson's Disease: A Randomized Controlled Examiner-Blinded Feasibility Clinical Trial.","authors":"Miriam van Emde Boas, Chatkaew Pongmala, Abigail M Biddix, Alexis Griggs, Austin T Luker, Giulia Carli, Uros Marusic, Nicolaas I Bohnen","doi":"10.22540/JFSF-09-267","DOIUrl":"10.22540/JFSF-09-267","url":null,"abstract":"<p><strong>Objective: </strong>Parkinson's patients will experience mobility disturbances with disease progression. Beneficial effects of physical therapy are short-lasting. Novel interventions are needed to maintain these benefits.</p><p><strong>Methods: </strong>Fourteen Parkinson's patients (71±4.08 years) participated in a randomized controlled examiner-blinded feasibility clinical trial. After 12 physical therapy sessions, the intervention group received a height-adjustable desk that facilitates stepping while standing, for 4 months. Explorative outcome measures included MDS-UPDRS II, III, TUG, 8.5m walking test, PDQ-39, sABC, sFES, DEXA scans, and lower extremity strength.</p><p><strong>Results: </strong>Post-physical-therapy, everyone significantly improved on the MDS-UPDRS II, III, TUG, and 8.5m walking test, and PDQ-39. (p<0.05) After 4 months, the control group regressed towards pre-physical-therapy values. In the intervention group, sedentary behavior decreased beyond desk use, indicating a carry-over effect. MDS-UPDRS II, PDQ-39, sFES, sABC, TUG, 8.5m walking test, activity time, sitting time, hip strength all improved with clinically relevant effect sizes.</p><p><strong>Conclusion: </strong>Post-physical therapy in-home reduction of sedentary behavior was associated with maintenance of physical benefits and additional improvements in mobility, activity time, balance and quality of life.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 4","pages":"267-280"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Thematic Analysis of Lived Experiences of Falls in Middle-Aged and Older Adults. 中老年人跌倒生活经历的专题分析。
Journal of frailty, sarcopenia and falls Pub Date : 2024-12-01 DOI: 10.22540/JFSF-09-249
Jodi P Ventre, Toni Hall, Paul S Holmes, Chesney E Craig
{"title":"A Thematic Analysis of Lived Experiences of Falls in Middle-Aged and Older Adults.","authors":"Jodi P Ventre, Toni Hall, Paul S Holmes, Chesney E Craig","doi":"10.22540/JFSF-09-249","DOIUrl":"10.22540/JFSF-09-249","url":null,"abstract":"<p><strong>Objectives: </strong>Fall-related injuries occur at a similar prevalence rate in middle-aged and older adults and may increase concerns about falling and future falls. No research to date has examined how experiences of falls and related concerns, differ between middle-aged and older fallers. This study aimed to address this using qualitative interviews.</p><p><strong>Methods: </strong>Ten middle-aged (55-64 years) and ten older adults (68-83 years) were interviewed about their experiences of falls and concerns about falling. Guided by a social constructivist epistemology, reflexive thematic analysis was used to categorise themes within the data.</p><p><strong>Results: </strong>Five overarching themes were identified. Four themes showed distinctions between groups (i) perceptions of age-related decline; (ii) ageism: stigma associated with 'fallers'; (iii) concerns about loss of independence; and (iv) unravelling perceived control. The fifth theme (v) perceptions of falls risk: concerns and awareness, demonstrated the most similarities.</p><p><strong>Conclusions: </strong>Whilst middle-aged and older fallers showed similar ratings of concern about falling, the behaviours underlying these were qualitatively different. For older adults, concerns led to protective adaptations to reduce their fall risk. Contrastingly, middle-aged adults showed a lack of personal responsibility over their fall risk. The findings highlight the importance of early educational intervention to reduce future falls and frailty.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 4","pages":"249-266"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modified Hospital Frailty Risk Score (mHFRS) as a Tool to Identify and Predict Outcomes for Hospitalised Older Adults at Risk of Frailty. 改进的医院虚弱风险评分(mHFRS)作为识别和预测住院老年人虚弱风险结局的工具
Journal of frailty, sarcopenia and falls Pub Date : 2024-12-01 DOI: 10.22540/JFSF-09-235
Lydia Sim, Ting Yu Chang, Kyaw Khine Htin, Aileen Lim, Thevapriya Selvaratnam, Simon Conroy, Kiat Sern Goh, Barbara Rosario
{"title":"Modified Hospital Frailty Risk Score (mHFRS) as a Tool to Identify and Predict Outcomes for Hospitalised Older Adults at Risk of Frailty.","authors":"Lydia Sim, Ting Yu Chang, Kyaw Khine Htin, Aileen Lim, Thevapriya Selvaratnam, Simon Conroy, Kiat Sern Goh, Barbara Rosario","doi":"10.22540/JFSF-09-235","DOIUrl":"10.22540/JFSF-09-235","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to determine whether modified Hospital Frailty Risk Score (mHFRS) can identify frail hospitalised older adults by comparing mHFRS to HFRS and Clinical Frailty Scale (CFS).</p><p><strong>Methods: </strong>A retrospective review was undertaken in patients =>65 years hospitalised following an Emergency Department attendance between 1<sup>st</sup> July 2022 and 31<sup>st</sup> March 2023. Predictive models were evaluated with correlation and measure of agreement between frailty risk scores, CFS and HFRS, CFS and modified HFRS (mHFRS) using the Spearman's rank correlation and Cohen's kappa (κ).</p><p><strong>Results: </strong>Of 3042 patients, CFS categorised 1635 (53.7%) patients as non-frail (CFS 1-4) and 1407 (46.3%) as frail (CFS 5-9,p<0.001). Frail patients were more likely to be female (55.9%), older (81.8 years, SD 8.41 vs 75.3 years, SD 7.20, p<0.001), with longer LOS (52.5% % vs 31.5%, p<0.001), higher 30-day emergency re-admission (18.5% vs 9.9%, p<0.001) and higher mortality at all time points. We could compute mHFRS for 1623 (53.4%) patients, of whom, 37.5% were low risk, 40.5% intermediate risk and 22.1% high frailty risk. mHFRS showed significant correlation with CFS (p<0.001) and HFRS (p<0.001), respectively and achieved comparable association with clinical outcomes.</p><p><strong>Conclusion: </strong>mHFRS was better at identifying non-frail patients and provides a novel, standardised and comparable frailty risk stratification tool for screening older hospitalised patients.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 4","pages":"235-248"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Youth Migration in Low-income Countries: Who is Going to Provide Care for the Frail Older Adults? 低收入国家的青年移民:谁来照顾体弱多病的老年人?
Journal of frailty, sarcopenia and falls Pub Date : 2024-12-01 DOI: 10.22540/JFSF-09-232
Jagadish K Chhetri
{"title":"Youth Migration in Low-income Countries: Who is Going to Provide Care for the Frail Older Adults?","authors":"Jagadish K Chhetri","doi":"10.22540/JFSF-09-232","DOIUrl":"10.22540/JFSF-09-232","url":null,"abstract":"","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 4","pages":"232-234"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11613975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Impact of Each Item of the SARC-F Questionnaire in Patients Undergoing Major Surgery for Urologic Cancer. SARC-F 问卷各项目对泌尿系统癌症大手术患者预后的影响
Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-201
Kohei Hirose, Shugo Yajima, Ryo Andy Ogasawara, Naoki Imasato, Sao Katsumura, Madoka Kataoka, Yasukazu Nakanishi, Hitoshi Masuda
{"title":"Prognostic Impact of Each Item of the SARC-F Questionnaire in Patients Undergoing Major Surgery for Urologic Cancer.","authors":"Kohei Hirose, Shugo Yajima, Ryo Andy Ogasawara, Naoki Imasato, Sao Katsumura, Madoka Kataoka, Yasukazu Nakanishi, Hitoshi Masuda","doi":"10.22540/JFSF-09-201","DOIUrl":"10.22540/JFSF-09-201","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to evaluate the association between scores on each item of the SARC-F questionnaire and life expectancy in patients undergoing major surgery for urologic cancer.</p><p><strong>Methods: </strong>This retrospective study included 1018 patients undergoing elective major urologic cancer surgery. All patients completed the SARC-F questionnaire preoperatively. Demographic and clinical data were collected. The primary endpoint was an association between SARC-F scores and overall survival (OS).</p><p><strong>Results: </strong>Of the 1018 patients, the median age was 72 years and 920 (90%) were male. Multivariate analysis revealed four factors significantly and independently associated with shorter OS: assistance with walking score ≥1 (Hazard ratio: HR=2.18, <i>P</i>=0.044), cancer stages ≥ III (HR=7.98, <i>P</i><0.001), high blood loss ≥78 ml or blood transfusion during surgery (HR=4.53, <i>P</i>=0.007 and HR=2.41, <i>P</i>=0.037, respectively).</p><p><strong>Conclusions: </strong>This study found that among the items of the SARC-F questionnaire, assistance with walking was a strong predictor of life expectancy. Incorporating such a simple screening tool into the preoperative assessment would help to ensure more appropriate perioperative care for urologic cancer patients.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"201-206"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can EWGSOP2 and SDOC Definitions of Sarcopenia Identify Functional Muscle Quality? EWGSOP2 和 SDOC 对 "肌肉疏松症 "的定义能否识别功能性肌肉质量?
Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-192
Patricia Parreira Batista, Monica Rodrigues Perracini, Daniele Sirineu Pereira, Juleimar Soares Coelho De Amorim, Leani Souza Máximo Pereira
{"title":"Can EWGSOP2 and SDOC Definitions of Sarcopenia Identify Functional Muscle Quality?","authors":"Patricia Parreira Batista, Monica Rodrigues Perracini, Daniele Sirineu Pereira, Juleimar Soares Coelho De Amorim, Leani Souza Máximo Pereira","doi":"10.22540/JFSF-09-192","DOIUrl":"10.22540/JFSF-09-192","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the European Working Group on Sarcopenia in Older People (EWGSOP2) and the Sarcopenia Definition and Outcomes Consortium (SDOC) in identifying muscle quality indexes (MQI) and lower limb muscle performance in older women aged ≥ 65.</p><p><strong>Methods: </strong>Participants meeting EWGSOP2 and SDOC criteria were classified into the sarcopenia group (GS); others were placed in the non-sarcopenia group (GNS). Using an isokinetic dynamometer, we assessed peak torque (PT), maximal work (MW), and power (POW) of lower limbs. MQI was calculated as the ratio of muscle performance to appendicular lean mass, adjusted for body mass index (BMI) and lean tissue mass of the right lower limb (LTM).</p><p><strong>Results: </strong>We included 96 older women. In both SDOC (n=37) and EWGSOP2 (n=48) sarcopenia groups, muscle performance and BMI-adjusted MQI were significantly lower. Sarcopenia (SDOC) was significantly associated with all lower limb muscle performance and MQI variables [adjusted model by age and race: MQI<sub>POW/LTM</sub> OR = 0.67 (95% CI 0.52; 0.85); MQI<sub>PT/LTM</sub> OR = 0.76 (95% CI 0.64; 0.89)].</p><p><strong>Conclusions: </strong>Older women diagnosed with sarcopenia by EWGSOP2 and SDOC criteria showed significant declines in muscle function and quality. The SDOC definition discriminated muscle contraction quality components in older individuals with and without sarcopenia.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"192-200"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Measurement and Reporting of Falls: Recommendations for Research on Falls Data Collection and Capturing Social Determinants of Health. 跌倒的测量和报告:关于跌倒数据收集和捕捉健康社会决定因素研究的建议》。
Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-166
Deborah A Jehu, Dawn A Skelton
{"title":"The Measurement and Reporting of Falls: Recommendations for Research on Falls Data Collection and Capturing Social Determinants of Health.","authors":"Deborah A Jehu, Dawn A Skelton","doi":"10.22540/JFSF-09-166","DOIUrl":"10.22540/JFSF-09-166","url":null,"abstract":"","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"166-168"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drugs with Anticholinergic Properties and Association with Hip Fractures in Older Patients: A Danish Nationwide Cohort-Study. 具有抗胆碱能特性的药物与老年患者髋部骨折的关系:丹麦全国队列研究
Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-207
Rebekka Vedelsbøl, Pavithra Laxsen Anru, Jesper Ryg
{"title":"Drugs with Anticholinergic Properties and Association with Hip Fractures in Older Patients: A Danish Nationwide Cohort-Study.","authors":"Rebekka Vedelsbøl, Pavithra Laxsen Anru, Jesper Ryg","doi":"10.22540/JFSF-09-207","DOIUrl":"10.22540/JFSF-09-207","url":null,"abstract":"<p><strong>Objectives: </strong>Hip fractures (HFx) resulting from falls are a significant health concern, and drugs with anticholinergic properties (DAP) increase the risk of falls. This study aimed to assess the association between use of DAP at hospital admission and HFx risk in older patients.</p><p><strong>Methods: </strong>This nationwide population-based study included all patients ≥65 years admitted to Danish geriatric wards during 2005-2014. Outcome of interest was first HFx within 2-years follow-up. The Anticholinergic Cognitive Burden (ACB) scale quantified DAP use. Cox regression analysis of data from four national registries was adjusted for activities of daily living, age, marital status, admission year, BMI, fracture history, previous admissions, dementia, anti-osteoporotic drugs, and Charlson comorbidity index.</p><p><strong>Results: </strong>74,589 patients (62.8% female) were included, 45,463 (60.9%) received DAP at index, and 7,861 HFx occurred during follow-up. Cumulative 2-year HFx hazard was highest for ACB=0 (15.3%). Higher ACB-score was not associated with increased HFx risk in univariable nor multivariable analyses. In sensitivity analysis, use of DAP with high anticholinergic burden (≥2) did not alter results.</p><p><strong>Conclusions: </strong>In this high-incidence national cohort, higher ACB-score was not associated with increased HFx risk. Our results call for further research on association between specific DAP and risk of HFx.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"207-217"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the Cycle of Physical Frailty in Falls Clinic Attendees Through Structural Equation Modeling. 通过结构方程模型研究跌倒门诊就诊者身体虚弱的周期。
Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-227
Román Romero Ortuño, Eoin Duggan
{"title":"Examining the Cycle of Physical Frailty in Falls Clinic Attendees Through Structural Equation Modeling.","authors":"Román Romero Ortuño, Eoin Duggan","doi":"10.22540/JFSF-09-227","DOIUrl":"10.22540/JFSF-09-227","url":null,"abstract":"<p><p>In 1998, Fried and Walston introduced the Cycle of Frailty (CF) as a foundational concept for defining the physical frailty phenotype (FP). While the FP has been extensively validated, the CF hypothesis lacks equivalent support. This study aimed to internally validate the CF using structural equation modeling (SEM) in a clinical dataset of adults aged 50 or older attending an outpatient falls clinic. Measures included: age, morbidity, nutrition, sarcopenia by bioelectrical impedance, VO<sub>2</sub>max, handgrip strength, basal metabolic rate (BMR), 5-times chair stand test (5CST), physical activity, and total energy expenditure (TEE). The SEM, incorporating CF hypothesized causal pathways, was tested using IBM® SPSS® Amos 27.0.0 (maximum likelihood method) with a sample of 102 adults (mean age 69.8 years, 58.8% women). Overall, the SEM was supported by the data (χ<sup>2</sup> = 44.4, df = 37, p = 0.189), with significant (p < 0.05) regression weights for morbidity→sarcopenia, age→sarcopenia, sarcopenia→VO<sub>2</sub>max, sarcopenia→handgrip strength, handgrip strength→5CST, physical activity→TEE, TEE→nutrition, and BMR→TEE. However, nutrition→sarcopenia, sarcopenia→BMR, VO<sub>2</sub>max→5CST, and 5CST→physical activity were not significant. Although the SEM was limited by inclusion of surrogate CF measures (e.g., 5CST instead of gait speed, VO<sub>2</sub>max based on age-predicted maximal/resting heart rate), it provided some internal support for the CF hypothesis.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"227-231"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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