Journal of frailty, sarcopenia and falls最新文献

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Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: A hypothesis-generating observational study. 养老院老年居民出现症状性COVID-19的危险因素:一项产生假设的观察性研究
Journal of frailty, sarcopenia and falls Pub Date : 2023-06-01 DOI: 10.22540/JFSF-08-074
Anna Escribà-Salvans, Sandra Rierola-Fochs, Pau Farrés-Godayol, Miriam Molas-Tuneu, Dyego Leandro Bezerra de Souza, Dawn A Skelton, Ester Goutan-Roura, Eduard Minobes-Molina, Javier Jerez-Roig
{"title":"Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: A hypothesis-generating observational study.","authors":"Anna Escribà-Salvans,&nbsp;Sandra Rierola-Fochs,&nbsp;Pau Farrés-Godayol,&nbsp;Miriam Molas-Tuneu,&nbsp;Dyego Leandro Bezerra de Souza,&nbsp;Dawn A Skelton,&nbsp;Ester Goutan-Roura,&nbsp;Eduard Minobes-Molina,&nbsp;Javier Jerez-Roig","doi":"10.22540/JFSF-08-074","DOIUrl":"https://doi.org/10.22540/JFSF-08-074","url":null,"abstract":"Background. COVID-19 pandemic has had a major impact on society, including on residents of nursing homes (NH), who have a higher risk of complications and mortality due their physical and intellectual disabilities. Aim. To identify which risk factors associated with developing COVID-19 infection with symptoms in institutionalized older people. Methods. A 1-year longitudinal multicenter study was conducted in 5 NH during the period December 2019 to March 2021. The inclusion criteria used were residents aged 65 years or over, living in the NH permanently, with a diagnostic test for COVID-19 confirmed by reverse transcription polymerase chain reaction and/or serological test. The main variable was symptomatic COVID-19, with at least one of the following symptoms (fever, respiratory difficulties, cough, diarrhea, sudden urinary incontinence and disorientation or delirium). Three assessments were performed: baseline, six and twelve months follow-up. Descriptive and bivariate analysis (calculating relative risk-RR) were performed, considering a 95% confidence level and a statistically significant p <0.05. Results. Of the total sample of 78 individuals who tested positive for COVID-19, mean age 84.6 years (SD=7.8), 62 (79.5%) were female; 40 (51.3%) participants presented with COVID-19 symptoms. Living in a private NH (RR=3.6, 95% CI [1.2-11.0], p =0.023) and having suffered a stroke (RR=4.1, 95% CI [1.1-14.7], p =0.033) were positively associated with developing COVID-19 infection with symptoms. Conclusions. Having suffered a stroke and living permanently in a private health care facility were positively associated with symptomatic COVID-19 in this sample of institutionalized older people.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"74-82"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/a7/JFSF-8-074.PMC10233324.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Women's perceptions or experiences of physical activity and exercise interventions to improve bone health: a systematic review. 妇女对身体活动和运动干预改善骨骼健康的看法或经验:系统综述。
Journal of frailty, sarcopenia and falls Pub Date : 2023-06-01 DOI: 10.22540/JFSF-08-094
C Ryanne Plesh, Rebecca A Withers, Dawn A Skelton
{"title":"Women's perceptions or experiences of physical activity and exercise interventions to improve bone health: a systematic review.","authors":"C Ryanne Plesh,&nbsp;Rebecca A Withers,&nbsp;Dawn A Skelton","doi":"10.22540/JFSF-08-094","DOIUrl":"https://doi.org/10.22540/JFSF-08-094","url":null,"abstract":"<p><p>Exercise is an important intervention to maintain bone health in women with osteopenia and osteoporosis. This systematic review aims to gain insight into the experiences or perceptions females have toward bone health interventions, to promote uptake and adherence. Four electronic databases were searched: MEDLINE, CINAHL, PubMed and PsycInfo. Inclusion Criteria: Qualitative studies examining perceptions or views of women to physical activity or exercise interventions aimed at improving bone health. 1,406 papers were identified. After screening, data were extracted from 2 studies considering experiences and 2 papers presenting perceptions of exercise for bone health. All studies scored >8 out of 10 on the CASP Quality Tool. Older women perceived barriers such as safety and advice, and facilitators of tangible results and feedback within supervised group sessions. Older womens' experiences of a digitally delivered exercise intervention included social interactions and voice reminders, with barriers of lack of feedback and knowledge. Younger women expressed enablers as feeling the benefits and physical literacy, and barriers of previous experience participating in tedious exercise. Supervised sessions, with different intensity levels and variety, offering feedback to promote confidence, are valuable to uptake and adherence in both younger and older females.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 2","pages":"94-106"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fe/e0/JFSF-8-094.PMC10233328.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Rheumatoid Arthritis and MUScle (RAMUS) Study: Protocol for an observational single-arm study of skeletal muscle in patients with rheumatoid arthritis receiving tofacitinib. 类风湿关节炎和肌肉(RAMUS)研究:接受托法替尼治疗的类风湿关节炎患者骨骼肌观察性单臂研究方案。
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-053
Joshua L Bennett, Maha Egail, Amy E Anderson, Richard Dodds, Catherine Feeney, Gráinne S Gorman, Arthur G Pratt, Avan A Sayer, Kieren G Hollingsworth, John D Isaacs
{"title":"The Rheumatoid Arthritis and MUScle (RAMUS) Study: Protocol for an observational single-arm study of skeletal muscle in patients with rheumatoid arthritis receiving tofacitinib.","authors":"Joshua L Bennett,&nbsp;Maha Egail,&nbsp;Amy E Anderson,&nbsp;Richard Dodds,&nbsp;Catherine Feeney,&nbsp;Gráinne S Gorman,&nbsp;Arthur G Pratt,&nbsp;Avan A Sayer,&nbsp;Kieren G Hollingsworth,&nbsp;John D Isaacs","doi":"10.22540/JFSF-08-053","DOIUrl":"https://doi.org/10.22540/JFSF-08-053","url":null,"abstract":"<p><p>People with rheumatoid arthritis (RA) are disproportionately affected by sarcopenia, the generalised loss of muscle strength and mass, consequently facing an increased risk of falls, functional decline and death. Currently, there are no approved pharmacological treatments for sarcopenia. RA patients who start tofacitinib (a Janus kinase inhibitor) develop small increases in serum creatinine that are not explained by renal function changes and could reflect sarcopenia improvement. The RAMUS Study is a proof of concept, single-arm observational study in which patients with RA who commence tofacitinib according to routine care will be offered participation according to eligibility criteria. Participants will undergo lower limb quantitative magnetic resonance imaging, whole-body dual energy x-ray absorptiometry, joint examination, muscle function testing and blood tests at three time points: prior to starting tofacitinib and 1 and 6 months afterwards. Muscle biopsy will be performed before and 6 months after starting tofacitinib. The primary outcome will be lower limb muscle volume changes following treatment initiation. The RAMUS Study will investigate whether muscle health improves following tofacitinib treatment for RA. Identifying a potential pharmacological treatment for sarcopenia could have important implications for individuals with RA and for older people in general. ISRCTN registry ID: 13364395.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"53-59"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/eb/JFSF-8-053.PMC9975967.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10837185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Sarcopenia in Rheumatoid arthritis. A narrative review. 类风湿性关节炎中的肌肉减少症。叙述性评论
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-044
Dimitra Moschou, Michail Krikelis, Christos Georgakopoulos, Evangelia Mole, Efstathios Chronopoulos, Symeon Tournis, Clio Mavragani, Konstantinos Makris, Ismene Dontas, Susana Gazi
{"title":"Sarcopenia in Rheumatoid arthritis. A narrative review.","authors":"Dimitra Moschou,&nbsp;Michail Krikelis,&nbsp;Christos Georgakopoulos,&nbsp;Evangelia Mole,&nbsp;Efstathios Chronopoulos,&nbsp;Symeon Tournis,&nbsp;Clio Mavragani,&nbsp;Konstantinos Makris,&nbsp;Ismene Dontas,&nbsp;Susana Gazi","doi":"10.22540/JFSF-08-044","DOIUrl":"https://doi.org/10.22540/JFSF-08-044","url":null,"abstract":"<p><p>Sarcopenia was recently identified as an entity in the ICD-10 classification of October 2016. According to the recommendation of the European Working Group on Sarcopenia in Older People (EWGSOP2), sarcopenia is defined as low muscle strength and low muscle mass, while physical performance is used to categorize the severity of sarcopenia. In recent years, sarcopenia has become increasingly common in younger patients with autoimmune diseases such as Rheumatoid arthritis (RA). Due to the chronic inflammation caused by RA, patients have reduced physical activity, immobility, stiffness, and joint destruction and all of that lead to the loss of muscle mass, muscle strength, disability and significantly lowering the patients' quality of life. This article is a narrative review about sarcopenia in RA, with a special focus in its pathogenesis and management.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"44-52"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/06/50/JFSF-8-044.PMC9975974.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The effectiveness of mental imagery on motor, cognitive and emotional status of older people with early-stage dementia: A study protocol. 心理意象对老年早期痴呆患者运动、认知和情绪状态的影响:一项研究方案。
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-060
Anna Christakou, Christina Bouzineki, Marousa Pavlou, George Stranjalis, Vasiliki Sakellari
{"title":"The effectiveness of mental imagery on motor, cognitive and emotional status of older people with early-stage dementia: A study protocol.","authors":"Anna Christakou,&nbsp;Christina Bouzineki,&nbsp;Marousa Pavlou,&nbsp;George Stranjalis,&nbsp;Vasiliki Sakellari","doi":"10.22540/JFSF-08-060","DOIUrl":"https://doi.org/10.22540/JFSF-08-060","url":null,"abstract":"<p><p>Dementia involves the loss of cognitive abilities and represents a decline from the prior level of function which impairs functional abilities in day-to-day life. No previous experimental research has been done to assess mental imagery (MI) effectiveness in the motor, cognitive and emotional status of individuals with early-stage dementia. One hundred and forty older individuals with early-stage dementia from the Day Care Centre of the Alzheimer Association in Athens will take part in this study. The sample will be randomly divided into three groups: MI and physical exercise (intervention group), only physical exercise (1<sup>st</sup> control group), and neither MI nor physical exercise (2<sup>nd</sup> control group). Assessment will be obtained one week prior to the program, in the middle of the program (6<sup>th</sup> week of the intervention program) and after the end of the program (13<sup>th</sup> week of the intervention program). Participants of the intervention group will perform a 30-minute MI programme after the end of every physiotherapy session. Reliable and valid instruments will be used to assess the primary outcomes, i.e., balance and functional status as well as the secondary outcomes i.e., cognitive ability, emotional state and quality of life. The two-way Mixed ANOVA with factors 'intervention' (between groups) and 'time' (within group) will be used as a statistical analysis. Approvals of clinical trial protocol: a) UNIWA Research Committee study protocol approval: 93292 - 26/10/2021. b) ClinicalTrials.gov: ID NCT05232526.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"60-65"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/01/JFSF-8-060.PMC9975972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9410799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Instructor and client views of a community falls prevention service and the impact of the COVID-19 pandemic: A qualitative exploration of a service in England. 教师和客户对社区预防跌倒服务的看法和COVID-19大流行的影响:对英格兰一项服务的定性探索。
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-009
Leah Jayes, Joanne R Morling, Sophie Carlisle, Ilze Bogdanovica, Tessa Langley
{"title":"Instructor and client views of a community falls prevention service and the impact of the COVID-19 pandemic: A qualitative exploration of a service in England.","authors":"Leah Jayes,&nbsp;Joanne R Morling,&nbsp;Sophie Carlisle,&nbsp;Ilze Bogdanovica,&nbsp;Tessa Langley","doi":"10.22540/JFSF-08-009","DOIUrl":"https://doi.org/10.22540/JFSF-08-009","url":null,"abstract":"<p><strong>Objectives: </strong>Falls are the most common cause of injury related deaths in people over 75 years. The aim of this study was to explore the experience of providers (instructors) and service users (clients) of a fall's prevention exercise programme and the impact of the COVID-19 pandemic in Derbyshire, UK.</p><p><strong>Methods: </strong>Ten one-to-one interviews with class instructors and five focus groups with clients (n=41). Transcripts were analysed using inductive thematic analysis.</p><p><strong>Results: </strong>Most clients were initially motivated to attend the programme to improve their physical health. All clients reported improvements in their physical health as a result of attending the classes; additional benefits to social cohesion were also widely discussed. Clients referred to the support provided by instructors during the pandemic (online classes and telephone calls) as a 'life-line'. Clients and instructors thought more could be done to advertise the programme, especially linking in with community and healthcare services.</p><p><strong>Conclusions: </strong>The benefits of attending exercise classes went beyond the intended purpose of improving fitness and reducing the risk of falls, extending into improved mental and social wellbeing. During the pandemic the programme also prevented feelings of isolation. Participants felt more could be done to advertise the service and increase referrals from healthcare settings.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"9-22"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/e0/JFSF-8-009.PMC9975971.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10837188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balance performance and grip strength as predictors of cognitive function among community-dwelling older adults in the USA. 平衡表现和握力作为美国社区老年人认知功能的预测因子。
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-023
Jennifer Blackwood, Reza Amini, Gerry Conti, Quinn Counseller, Rebekah Taylor, Deena Fayyad
{"title":"Balance performance and grip strength as predictors of cognitive function among community-dwelling older adults in the USA.","authors":"Jennifer Blackwood,&nbsp;Reza Amini,&nbsp;Gerry Conti,&nbsp;Quinn Counseller,&nbsp;Rebekah Taylor,&nbsp;Deena Fayyad","doi":"10.22540/JFSF-08-023","DOIUrl":"https://doi.org/10.22540/JFSF-08-023","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate how balance and grip strength predicts the probability of cognitive function impairment (i.e., executive function: mild and mild-to-moderate impairment, and delayed recall) over eight years in community-dwelling older adults in the US, controlling for sex and race/ethnicity.</p><p><strong>Methods: </strong>The National Health and Aging Trends Study dataset (2011 - 2018) was employed. Dependent variables included the Clock Drawing Test (Executive Function) and Delayed Word Recall Test. Longitudinal ordered logistic regression examined the association between cognitive function and predictors (i.e., balance and grip strength) over eight waves (n=9800, 1,225 per wave).</p><p><strong>Results: </strong>Those who could complete side-by-side standing and semi-tandem tasks were 33% and 38% less likely to have mild or mild-to-moderate executive function impairment, respectively, relative to those who could not complete these tests. One score decrease in grip strength increased the executive function impairment risk by 13% (Odds Ratio: 0.87, CI: 0.79-0.95). Those who completed the side-by-side tasks were 35% (Odds Ratio: 0.65, CI: 0.44-0.95) less likely to experience delayed recall impairments than those who could not complete this test. With one score decrease in grip strength, the risk of delayed recall impairment was increased by 11% (OR: 0.89, CI: 0.80-1.00).</p><p><strong>Conclusions: </strong>A combination of these two simple tests (i.e., semi-tandem stance and grip strength) can screen for cognitive impairment among community-dwelling older adults to identify people with mild and mild-to-moderate cognitive impairment in clinical settings.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"23-31"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/1d/JFSF-8-023.PMC9975970.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of sarcopenia, fear of COVID-19, anxiety, depression and physical activity levels: Associations across patients on hemodialysis within Greece. 肌肉减少症风险、对COVID-19的恐惧、焦虑、抑郁和身体活动水平:希腊血液透析患者之间的关联
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-032
Maria Tsekoura, Nikolaos Kalampakos, Konstantinos Fousekis, Konstantinos Mylonas, Pavlos Angelopoulos, Charalampos Matzaroglou, Theodora Bita, John Gliatis, Elias Tsepis, Evdokia Billis
{"title":"Risk of sarcopenia, fear of COVID-19, anxiety, depression and physical activity levels: Associations across patients on hemodialysis within Greece.","authors":"Maria Tsekoura,&nbsp;Nikolaos Kalampakos,&nbsp;Konstantinos Fousekis,&nbsp;Konstantinos Mylonas,&nbsp;Pavlos Angelopoulos,&nbsp;Charalampos Matzaroglou,&nbsp;Theodora Bita,&nbsp;John Gliatis,&nbsp;Elias Tsepis,&nbsp;Evdokia Billis","doi":"10.22540/JFSF-08-032","DOIUrl":"https://doi.org/10.22540/JFSF-08-032","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this multicenter cross-sectional study was to investigate the association between SARC-F, fear of COVID 19, anxiety, depression and physical activity in patients undergoing hemodialysis.</p><p><strong>Methods: </strong>This study was conducted in 3 hemodialysis centers in Greece during the period of the COVID-19 pandemic. Sarcopenia risk was assessed using the Greek version of SARC-F (≥4). Demographic and medical history were collected from the patient's medical charts. The participants were also asked to fill the Fear of COVID-19 Scale (FCV-19S), the Hospital Anxiety and Depression Scale (HADS), and the International Physical Activity Questionnaire (IPAQ) questionnaire.</p><p><strong>Results: </strong>A hundred and thirty-two (132) patients on hemodialysis (92 men, 70.75±13.14 years) were enrolled. Sarcopenia risk (utilizing the SARC-F) was found in 41.7% of patients on hemodialysis. The average duration of hemodialysis was 3.94±4.58 years. The mean score values for SARC-F, FCV-19S and HADS were 3.9±2.57, 21.08±5.32, and 15.02±6.69, respectively. The majority of patients were physically inactive. The SARC-F scores were strongly associated with age (r=56; p<0.001), HADS (r=0.55; p<0.001), levels of physical activity (r=0.5; p<0.001), but not with FCV-19S (r=0.27; p<0.001).</p><p><strong>Conclusion: </strong>A statistically significant relationship was recorded between sarcopenia risk and age, anxiety/depression and levels of physical inactivity in patients on hemodialysis. Future studies are necessary in order to evaluate the association of specific characteristics of patients.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"32-37"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/21/JFSF-8-032.PMC9975969.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sarcopenia: An Assessment into the Prevalence and Disease Burden in Chronic Pancreatitis Patients. 肌肉减少症:慢性胰腺炎患者患病率和疾病负担的评估。
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-038
Taiwo Oyebola, Akash Mavilakandy, James A Stephenson, Ruth Boyce, Neil Bhardwaj, Giuseppe Garcea
{"title":"Sarcopenia: An Assessment into the Prevalence and Disease Burden in Chronic Pancreatitis Patients.","authors":"Taiwo Oyebola,&nbsp;Akash Mavilakandy,&nbsp;James A Stephenson,&nbsp;Ruth Boyce,&nbsp;Neil Bhardwaj,&nbsp;Giuseppe Garcea","doi":"10.22540/JFSF-08-038","DOIUrl":"https://doi.org/10.22540/JFSF-08-038","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the prevalence of sarcopenia in patients referred to a Multidisciplinary Chronic Pancreatitis (CP) Clinic at the University Hospitals of Leicester.</p><p><strong>Methods: </strong>All patients who had undergone CT scans were identified. Controls were identified from CT colonograms with no features of malignancy or pancreatic pathology. The psoas muscle index (PMI) was calculated using the formula: total psoas muscle cross-sectional area at the third lumbar vertebral level (cm<sup>2</sup>)/ the patient's height squared (m<sup>2</sup>). PMI cut-offs were <6.31cm<sup>2</sup>/m<sup>2</sup> and <3.91cm<sup>2</sup>/m<sup>2</sup> for males and females, respectively.</p><p><strong>Results: </strong>58 CP CT scans were available for analysis along with 62 control scans. 71.9% of CP patients had a PMI below the cut-off for their gender, compared to 45.2% of the controls. The mean PMI (±SD) for male CP patients and male controls were 5.54cm<sup>2</sup>/m<sup>2</sup> (±1.60) and 6.73 cm<sup>2</sup>/m<sup>2</sup> (±1.54), (<i>P</i>=0.0023). The mean PMI (±SD) for female CP patients and female controls were 3.82 cm<sup>2</sup>/m<sup>2</sup> (+/-1.46) and 4.98 cm<sup>2</sup>/m<sup>2</sup> (+/-1.43), (<i>P</i>=0.0021).</p><p><strong>Conclusions: </strong>CP patients had a mean PMI below the cut-off value, suggesting that CP patients are largely sarcopenic. As malnutrition is a significant feature of CP, optimisation of nutrition may help to ameliorate sarcopenia in CP patients.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"8 1","pages":"38-43"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/2b/JFSF-8-038.PMC9975973.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Muscle power predicts frailty status over four years: A retrospective cohort study of the National Health and Aging Trends Study. 肌肉力量预测衰弱状态超过四年:国家健康和老龄化趋势研究的回顾性队列研究。
Journal of frailty, sarcopenia and falls Pub Date : 2023-03-01 DOI: 10.22540/JFSF-08-001
Caitlin M Burbank, Adam Branscum, Marit L Bovbjerg, Karen Hooker, Ellen Smit
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