Interdisciplinary cardiovascular and thoracic surgery最新文献

{"title":"Operative technique: Sutureless type ii hybrid arch repair for acute type A aortic dissection.","authors":"John Chien-Hwa Chang, Shih-Ming Huang, Ing-Heng Hii, Chi-Fu Cheng, Pei-Chei Lu, Yi-Tso Cheng","doi":"10.1093/icvts/ivaf081","DOIUrl":"https://doi.org/10.1093/icvts/ivaf081","url":null,"abstract":"<p><strong>Objectives: </strong>Hybrid arch repair improved surgical outcomes in aneurysmal disease. Sutureless anastomosis using an intraluminal ringed graft and stent graft bridging has been reported. We incorporate the vascular ring connector, angiography-assisted sutureless telescoping anastomosis technique, and thoracic endovascular aortic repair, rendering the hybrid arch repair for acute type A aortic dissection sutureless. Herein, we presented our sutureless procedure for acute type A aortic dissection.</p><p><strong>Methods: </strong>Between January 2022 and April 2023, 19 patients who underwent sutureless type II hybrid arch repair were enrolled. The surgical procedures were described. The preoperative demographics, operative details, postoperative outcomes, and follow-up results were retrospectively collected.</p><p><strong>Results: </strong>Nineteen patients with a median age of 62 (interquartile range, 10.5) and male dominant in 73.7% were recorded. The sutureless type II hybrid arch repair was performed in a median operative time of 397 min (interquartile range: 111.5), with a cardiopulmonary bypass time of 184 min (IQR: 52.5). The fully sutureless type II hybrid arch repair further reduced the abovementioned times. In-hospital death was two in 10.5%. Seventeen discharged patients had regular follow-ups in a median of 553 days (IQR: 129). The serial computed tomography scan revealed all reconstructed arch vessels were patent, and positive aortic remodelling was observed at the arch and thoracic endoprosthesis levels at 100% and 94.2%, respectively.</p><p><strong>Conclusions: </strong>Sutureless type II hybrid arch repair is feasible, demonstrating complete procedural success and favourable postoperative outcomes in mid-term follow-up. Long-term monitoring is necessary to assess this procedure's durability and potential complications.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic assisted left atrial appendage occlusion: an important complementary option in the surgical management of atrial fibrillation.","authors":"Alfonso Agnino, Laura Giroletti, Eduardo Celentano, Ascanio Graniero, Ernesto Cristiano, Matteo Parrinello, Giovanni Albano, Mario Gasparri, Stefano Schena","doi":"10.1093/icvts/ivaf082","DOIUrl":"https://doi.org/10.1093/icvts/ivaf082","url":null,"abstract":"<p><strong>Objectives: </strong>The growing popularity of minimally invasive treatment of AF has shown increasing interest in concomitant left atrial appendage occlusion (LAAO). Surgical robotic technology adds advantages such as magnified visualization, enhanced dexterity of movement and decreased invasiveness. Aim of this study is to evaluate effectiveness and early outcomes of robotic-assisted LAAO.</p><p><strong>Methods: </strong>This is an observational, multicentre, retrospective study of patients with AF who underwent robotic-assisted LAAO. In-hospital mortality, perioperative complications, LOS and imaging-driven (cardiac CT scan, TEE) efficacy at 3-month follow-up were analyzed.</p><p><strong>Results: </strong>Between August 2019 and June 2024, 194 patients with documented AF (70.4% male, mean age 67.7 ± 10.1) underwent robotic-assisted epicardial LAAO. The procedure was performed under transoesophageal-echocardiography guidance in 193 patients without complications. In one patient with previous sternotomy, LAAO was not feasible. Blood products transfusion was necessary in one patient, due to significant chest wall bleeding requiring thoracoscopic re-exploration. No stroke or thromboembolic events were observed. Left hemidiaphragm paralysis requiring plication occurred in 3 pts (1.5%). Hospital mortality was 0%. Mean LOS time was 2.2 days (range 1-10 days) and all patients were discharged home. Imaging follow-up was complete in 157 cases (81%) and was achieved by TEE in 91 patients while the remaining 66 underwent cardiac CT scan. Two patients had residual flow in the left atrial appendage and OAC was continued at follow-up.</p><p><strong>Conclusions: </strong>Robotic-assisted LAAO is safe with satisfactory outcome both in an isolated setting and with concomitant hybrid ablating procedures for patients with AF.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143805035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salvage surgery is safe and effective for clinical stage iii non-small cell lung cancer.","authors":"Xun Luo, J W Awori Hayanga, Elwin Tham, Kenneth Ryan, Paul Rothenberg, J Hunter Mehaffey, Jason Lamb, Shalini Reddy, Vinay Badhwar, Alper Toker","doi":"10.1093/icvts/ivaf084","DOIUrl":"https://doi.org/10.1093/icvts/ivaf084","url":null,"abstract":"<p><strong>Objectives: </strong>The utility of surgery for stage-III NSCLC has yet no consensus. Surgery is mainly deployed in a planned multimodality regimen, or as a salvage option after definite chemoradiation. We sought to explore outcomes after salvage surgery, planned surgery, or oncological treatment alone for clinical stage-III NSCLC.</p><p><strong>Methods: </strong>We identified clinical stage-III NSCLC from the National Cancer Database between 2010-2020. We used timing between radiation and surgical resection to define salvage surgery vs planned surgery. Surgery performed after 3-month following radiation was considered as salvage surgery. We performed propensity score matching to match planned surgery and oncologic treatment alone group to salvage surgery to account for patient and clinical characteristics. After matching, we compared their overall survival. Between salvage surgery and planned surgery, we further compared perioperative outcomes (short-term mortality, 30-day readmission, and length of stay).</p><p><strong>Results: </strong>Among 143,299 patients, 692 (0.5%) underwent salvage surgery and 25,598 (17.9%) underwent planned surgery. Median time from radiation to salvage surgery was 118 days. After the propensity score matching, 10-year survival of salvage surgery (34.6%) or planned surgery (34.5%) was higher than oncological treatment alone (16.8%). 30-day mortality (2.3% vs 3.1%), 90-day mortality (5.1% vs 6.0%), 30-day readmission (3.3% vs 4.2%), length of stay (5 vs 5) were similar between salvage and planned surgery.</p><p><strong>Conclusions: </strong>Salvage surgery conferred better survival than oncologic treatment alone, and similar long term survival and perioperative outcomes with planned surgery. Salvage surgery is a safe and effective option for stage-III NSCLC as planned surgery in selected patients.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143805036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High incidence of permanent pacemaker after Cox-maze IV and mitral valve surgery: A nationwide registry-based study.","authors":"Torbjörn Ivert, Gabriella Boano, Farkas Vanky, Fredrik Gadler, Anders Holmgren, Lena Jidéus, Birgitta Johansson, Göran Kennebäck, Shahab Nozohoor, Henrik Scherstén, Johan Sjögren, Anders Wickbom, Örjan Friberg, Anders Albåge","doi":"10.1093/icvts/ivaf085","DOIUrl":"https://doi.org/10.1093/icvts/ivaf085","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the long-term risk of permanent pacemaker implantation following Cox-maze IV (CMIV) and concurrent mitral valve surgery.</p><p><strong>Methods: </strong>A retrospective, nationwide, registry-based analysis was conducted on postoperative permanent pacemaker implantation in 397 patients with symptomatic mitral valve insufficiency and atrial fibrillation who underwent CMIV and mitral valve surgery in Sweden between 2009 and 2017. They were compared to a registry group of 346 patients with atrial fibrillation who underwent mitral valve surgery without surgical ablation during 2014-2017. The follow-up ended on September 30, 2022.</p><p><strong>Results: </strong>CMIV patients were on average four years younger and had lower surgical risk than registry patients. More CMIV patients underwent early (<30 days) pacemaker implantation (13.3% vs 5.5%, p = 0.002). CMIV patients had a doubled adjusted risk of requiring a pacemaker compared to registry patients after 8 years [HR 1.96, 95% CI 1.27-3.04]. In the CMIV group, 22% (95% CI 18-26%) had a pacemaker by 5 years, increasing to 27% (95% CI 22-31%) by 8 years, compared to 13% (95% CI 10-17%) at both time intervals in the registry group. Atrioventricular block II/III accounted for >60% of early pacemaker indications in both groups, and sinus node dysfunction was the indication for late pacemaker implantation in 48% in the CMIV group.</p><p><strong>Conclusions: </strong>Patients undergoing CMIV concomitant with mitral valve surgery have a higher rate of postoperative pacemaker implantation compared to patients with atrial fibrillation undergoing mitral valve surgery alone. Sinus node dysfunction was the main indication for late pacemaker among CMIV patients.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term mortality after coronary surgery in women patients depend on diabetes and age.","authors":"Victor Dayan, Juan Andres Montero, Maximiliano Hernandez, Carolina Sosa, Santiago Cubas, Stefano Urso, Rafael Sadaba, Nick Freemantle","doi":"10.1093/icvts/ivaf069","DOIUrl":"10.1093/icvts/ivaf069","url":null,"abstract":"<p><strong>Objectives: </strong>There is general consensus of the higher short-term risk in women after coronary artery bypass grafts (CABG), nonetheless, long-term survival is a matter of debate. We aimed to compare in a national database with over 10 years of follow-up long-term survival in women versus men and its interaction with diabetes and age.</p><p><strong>Methods: </strong>This is a national retrospective cohort study from Uruguay. Patients were included if they underwent isolated CABG between 1 January 2002 and 31 December 2022. The primary outcome was survival. The secondary outcome was a composite of operative mortality, postoperative stroke, deep sternal wound infection and kidney failure requiring dialysis. Interaction of age and diabetes was explored in the survival analysis after adjusting for baseline characteristics.</p><p><strong>Results: </strong>During the included study period, 21 959 patients (5778 were women) underwent isolated CABG in Uruguay. Among people with diabetes, women had worse survival, while no differences between gender were found in the non-diabetic population. Survival at 1 year after CABG was significantly lower in women (hazard ratio (HR) = 1.20; 95% confidence interval (CI): 1.07, 1.35; P = 0.002). Survival after 1-year was higher in women (P < 0.001). Absence of diabetes improved survival (HR = 0.83; 95% CI: 0.77, 0.89; P < 0.001), while presence of diabetes made survival between men and women similar (HR = 1.00; 95% CI: 0.92, 1.09; P = 0.946). Interaction between age and gender showed that women older than 60 years old had better survival than men. Composite outcome was worse in women (OR = 1.47; 95% CI: 1.24, 1.75).</p><p><strong>Conclusions: </strong>Women patients have worse overall mortality but better long-term survival than men. Diabetes and age have significant interaction with the long-term outcomes. Better survival is seen in women older than 60 years old.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous ruptured congenital bronchial diverticulum presenting with total lung collapse and chronic empyema thoracic.","authors":"Padungkiat Tangpiroontham","doi":"10.1093/icvts/ivaf060","DOIUrl":"10.1093/icvts/ivaf060","url":null,"abstract":"<p><p>Spontaneous rupture of a congenital bronchial diverticulum resulting in total lung collapse and chronic empyema thoracis is a rare condition that presents considerable challenges in preoperative diagnosis and perioperative management. Thorough interpretation of imaging studies and bronchoscopy is crucial for effective surgical planning. This article describes a successful surgical intervention employing primary repair in conjunction with decortication.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical results of combined aortic valve-sparing root replacement and mitral valve repair.","authors":"Veronica Lorenz, Jama Jahanyar, Stefano Mastrobuoni, Antonio Segreto, Luca Zanella, Gaby Aphram, Matteo Pettinari, Gebrine El Khoury, Laurent De Kerchove","doi":"10.1093/icvts/ivaf067","DOIUrl":"10.1093/icvts/ivaf067","url":null,"abstract":"<p><strong>Objectives: </strong>Aortic valve-sparing root replacement using the reimplantation technique and mitral valve (MV) repair are well-established surgical approaches for the treatment of aortic root pathologies and mitral valve insufficiency. However, the management of concomitant diseases with a dual valve-preserving strategy remains poorly described. Therefore, the aim of this study is to evaluate the long-term outcomes of concomitant valve-sparing surgery and MV repair.</p><p><strong>Methods: </strong>This case series includes all the patients who underwent combined valve-sparing root replacement and MV repair at Cliniques Universitaires Saint-Luc (Brussels, Belgium) between January 2000 and June 2022. Actual survival rate and freedom from reoperation were calculated by the Kaplan-Meier method, and the log rank test was used for statistical evaluation.</p><p><strong>Results: </strong>Forty-five patients were included in the study; they were divided into two groups (13 patients with and 32 patients without connective tissue disorders). There was no hospital mortality. Three patients (7%) required pacemaker implantation. Overall survival at 10 years was 90% (95% confidence interval [CI]: 64-97%). Furthermore, freedom from all reoperations at 10 years was 84% (95% CI: 64-93%). Analysing the two subgroups, we found no statistically significant difference in terms of 10-year survival (log rank P = 0.146). However, freedom from reoperation at 10 years was significantly lower in the connective tissue disorder group (63% vs 91%, log rank P = 0.031). Most patients treated with transaortic edge-to-edge repair required MV reoperation.</p><p><strong>Conclusions: </strong>Combined valve-sparing root replacement with the reimplantation technique and MV operations are complex surgeries. However, they can be performed safely, with excellent long-term survival and repair durability. Applying standard Carpentier techniques for MV repair is crucial, especially in patients with connective tissue disorders.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of diaphragm paralysis and its surgical interventions on outcomes after the staged Fontan procedure.","authors":"Ruxandra Dumitru, Muneaki Matsubara, Thibault Schaeffer, Takuya Osawa, Jonas Palm, Carolin Niedermaier, Nicole Piber, Paul Philipp Heinisch, Bettina Ruf, Alfred Hager, Peter Ewert, Jürgen Hörer, Masamichi Ono","doi":"10.1093/icvts/ivaf072","DOIUrl":"10.1093/icvts/ivaf072","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the incidence of diaphragm paralysis and its impact on outcomes after the Fontan procedure in patients with single ventricles.</p><p><strong>Methods: </strong>Patients undergoing staged Fontan palliation between 1994 and 2023 were reviewed. Patients who had diaphragm paralysis were identified, and the impact of diaphragm paralysis on outcomes after Fontan completion was evaluated.</p><p><strong>Results: </strong>Among 601 patients who underwent staged Fontan completion during the study period, diaphragm paralysis was observed in 79 patients (13.1%) before Fontan (33 after stage I palliation and 46 after Glenn) and in 32 patients (5.3%) after the Fontan. Among 111 patients with diaphragm paralysis, 77 had spontaneous recovery, 13 recovered after plication and 21 remained without recovery. Patients with diaphragm paralysis before the Fontan demonstrated higher pulmonary arterial pressure (median 10 vs 9 mmHg, P = 0.045) and lower pulmonary artery symmetry index (median 0.54 vs 0.59, P = 0.046) than those without diaphragm paralysis. The use of an autologous pericardial patch in stage 1 was a risk factor for diaphragm paralysis development (odds ratio: 2.61, P = 0.012). Diaphragm paralysis was associated with an increased risk of protein-losing enteropathy (hazard ratio: 2.31, P = 0.003), particularly in patients without recovery after plication (hazard ratio: 4.85, P = 0.031).</p><p><strong>Conclusions: </strong>Diaphragm paralysis following Fontan completion significantly increases the risk of protein-losing enteropathy and long-term mortality, particularly in patients who fail to recover after plication. Early identification and appropriate management of diaphragm paralysis may be crucial for optimizing outcomes.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First reported surgical explantation of infected thoracic branched endograft requiring complex arch and descending thoracic aortic repair.","authors":"Michael A Catalano, Cecillia Chin, Nimesh D Desai, Kendall M Lawrence","doi":"10.1093/icvts/ivaf073","DOIUrl":"10.1093/icvts/ivaf073","url":null,"abstract":"<p><p>We present a 51-year-old woman with thoracic aortitis and rapidly enlarging descending thoracic aortic aneurysm in the setting of Clostridium septicum bacteraemia. After antibiotic treatment, she underwent left carotid-subclavian transposition and endovascular repair with thoracic branched endograft (TBE) with left carotid artery coverage. Three months postoperatively, she developed endograft infection, with a rapidly enlarging pseudoaneurysm at the proximal landing zone. She underwent TBE explant and descending thoracic aortic reconstruction. This report illustrates a rare complication and the first described surgical TBE explantation.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective evaluation of the Moleculight i:X™ in the early detection of driveline infections.","authors":"Angelina Olbrich, Arash Motekallemi, Heinz Deschka, Heinrich Rotering, Jürgen Sindermann, Nana-Maria Wagner, Henryk Welp, Angelo M Dell'Aquila","doi":"10.1093/icvts/ivae215","DOIUrl":"10.1093/icvts/ivae215","url":null,"abstract":"<p><strong>Objectives: </strong>Driveline infection (DLI) is a common complication in patients with left ventricular assist devices. This complication can seriously undermine quality of life while on left ventricular assist devices. Current diagnosis of a DLI in the outpatient setting is based on clinical examination and later bacteria isolation. The Moleculight i:XTM is a handheld fluorescence imaging device capable to visualize bacterial colonization in real-time. We here evaluated the performance of the Moleculight i:XTM for diagnosis of DLIs as this device may have the potential advantage to rapidly identify infection and therefore promptly influence therapy.</p><p><strong>Methods: </strong>A total of 107 examinations in patients with suspected DLIs were prospectively included in this study. All examinations took place in the outpatient setting. In addition to the standard treatment, Moleculight fluorescence images were captured and swabs were taken at the area of maximal luminosity. Wounds and pictures were reviewed and classified as positive or negative by a wound specialist and two heart surgeons independently from microbiological results.</p><p><strong>Results: </strong>The Moleculight i:XTM showed positive results (red fluorescence) in 19 cases (17.76%), whereas microbiological examination was positive for microorganisms in 74 cases (69.16%). The most common bacteria was Staphylococcus aureus. The findings resulted in a sensitivity of 13.51% and a specificity of 72.73%. The positive predictive value was 52.63% and the negative predictive value was 27.27%. Sub-analyses of different wound dressings or previous antibiotic treatment did not show any relevant difference.</p><p><strong>Conclusions: </strong>The results of the Moleculight i:X show a low sensitivity and specificity when being used to detect DLIs in the outpatient setting. Clinical examination and swabs should remain the gold standard despite the delay for bacteria isolation and consequent antibiotic treatment. Sensitivity and specificity of the Moleculight i:X in open wounds after surgical revision of the driveline remain to be clarified.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}