Interdisciplinary cardiovascular and thoracic surgery最新文献

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Early Supervised Incremental Resistance Training Versus Standard Care Following Median Sternotomy-A Preliminary Analysis of a Randomized Controlled Trial. 早期监督下的增量阻力训练与中位胸骨切开术后的标准治疗——随机对照试验的初步分析。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-05-05 DOI: 10.1093/icvts/ivag085
Nur Ayub Mohd Ali, Mohd Ali Katijjahbe, Doa El-Ansary, Nor Azura Azmi, Tze Huat Chong, Alistair Royse, Ahmad Lutfi Ahmad Bazli, Hairulfaizi Haron, Yuen Wen Adzim Poh, Mohd Rizal Abdul Manaf, Muhammad Ishamuddin Ismail
{"title":"Early Supervised Incremental Resistance Training Versus Standard Care Following Median Sternotomy-A Preliminary Analysis of a Randomized Controlled Trial.","authors":"Nur Ayub Mohd Ali, Mohd Ali Katijjahbe, Doa El-Ansary, Nor Azura Azmi, Tze Huat Chong, Alistair Royse, Ahmad Lutfi Ahmad Bazli, Hairulfaizi Haron, Yuen Wen Adzim Poh, Mohd Rizal Abdul Manaf, Muhammad Ishamuddin Ismail","doi":"10.1093/icvts/ivag085","DOIUrl":"10.1093/icvts/ivag085","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the safety and feasibility of implementing a supervised incremental UL resistance training program in the early postoperative period, and to investigate its initial effects on UL function and patient-reported pain at four weeks and three months after median sternotomy.</p><p><strong>Methods: </strong>This study is a report of the preliminary analysis of a phase II prospective, double-blind, randomized controlled trial that tested the Early Supervised Incremental Resistance Training intervention following a median sternotomy and explored its effects on upper limb function and patient-reported pain at 4 weeks and at 3 months.Primary outcomes were safety (defined by sternal wound complications); feasibility (assessed by recruitment and adherence); and upper limb function (measured by the Unsupported Upper Limb Exercise Test). Secondary outcomes included the Functional Difficulty Questionnaire Shortened Version and pain using the Numeric Rating Scale. Assessments occurred at baseline, discharge, 4 weeks and 3 months postoperatively.</p><p><strong>Results: </strong>Fifty-five participants were recruited (Early Supervised Incremental Resistance Training, n = 27; standard care, n = 28). No sternal complications occurred (relative risk, 0.963; 95% confidence interval, 0.057-16.21). Adherence was 80%, with no dropouts. Between-group differences in the Unsupported Upper Limb Exercise Test were not significant at 4 weeks (mean difference (MD), 1.49; 95% confidence interval, -4.62 to 7.16) or 3 months (mean difference (MD) 1.19; 95% confidence interval, -5.58 to 7.79). No significant differences were found for the Functional Difficulty Questionnaire Shortened Version or the Numeric Rating Scale. Within-group analyses showed significant improvements in the Unsupported Upper Limb Exercise Test, the Functional Difficulty Questionnaire Shortened Version and the Numeric Rating Scale over time.</p><p><strong>Conclusions: </strong>The Early Supervised Incremental Resistance Training was safe, feasible and well-accepted in the acute inpatient setting, with strong recruitment and adherence and no adverse events.</p><p><strong>Trial registration: </strong>ISRCTN 17842822, registered 11 March 2020.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147493933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hidden Cavities and the Illusion of Margin Sufficiency in Deep Wedge Resection. 深楔切除术中隐腔与边缘充分性错觉。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-05-05 DOI: 10.1093/icvts/ivag116
Kishankumar Mahida, Snehal Rajendra Jagtap
{"title":"Hidden Cavities and the Illusion of Margin Sufficiency in Deep Wedge Resection.","authors":"Kishankumar Mahida, Snehal Rajendra Jagtap","doi":"10.1093/icvts/ivag116","DOIUrl":"10.1093/icvts/ivag116","url":null,"abstract":"","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Aortic Arch Replacement With the Frozen Elephant Trunk Technique: Influence of Aortic Arch Anomalies. 冷冻象鼻技术全主动脉弓置换术:主动脉弓异常的影响。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-05-05 DOI: 10.1093/icvts/ivag100
Alessandro Leone, Silvia Snaidero, Luca Di Marco, Chiara Nocera, Davide Pacini
{"title":"Total Aortic Arch Replacement With the Frozen Elephant Trunk Technique: Influence of Aortic Arch Anomalies.","authors":"Alessandro Leone, Silvia Snaidero, Luca Di Marco, Chiara Nocera, Davide Pacini","doi":"10.1093/icvts/ivag100","DOIUrl":"10.1093/icvts/ivag100","url":null,"abstract":"<p><strong>Objectives: </strong>To assess surgical challenges and outcomes associated with arch anomalies in patients undergoing frozen elephant trunk (FET) for acute and chronic dissections.</p><p><strong>Methods: </strong>From January 2007 to January 2024, 401 patients underwent FET procedure in our centre. We included 285 patients with acute type A/B, chronic type A/B, and residual dissection. Patients were divided into normal arch group (n = 216) and arch anomalies group (n = 69), including aberrant right subclavian artery, bovine trunk, arch vertebral artery, and gothic arch.</p><p><strong>Results: </strong>Overall in-hospital mortality was 15.4% (17.4% in arch anomalies vs 14.8% in arch normal). In-hospital thoracic endovascular aortic repair (TEVAR) occurred in 7.2% (n = 5) of patients with arch anomalies. Stent graft-induced new entry tear at follow-up was 26.1% in arch anomalies vs 17.1% in arch normal group. Long-term survival in the overall patients was not different between the 2 groups (P = .383). In the subgroup of patients treated for chronic aortic dissection, freedom from TEVAR was higher in those with normal arch anatomy (P = .026).</p><p><strong>Conclusions: </strong>Aortic arch anomalies, especially in chronic dissection, were associated with increased endovascular reintervention. The gothic arch is the most challenging configuration due to frequent stent kinking.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13152671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeted Sequencing of Human Aorta Tissue Reveals Undiagnosed Heritable Thoracic Aortic Disease. 人类主动脉组织的靶向测序揭示了未确诊的遗传性胸主动脉疾病。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-05-05 DOI: 10.1093/icvts/ivag102
Ha Lee, Yoonjung Kim, Myeong Su Kim, Kyung-A Lee, Suk-Won Song
{"title":"Targeted Sequencing of Human Aorta Tissue Reveals Undiagnosed Heritable Thoracic Aortic Disease.","authors":"Ha Lee, Yoonjung Kim, Myeong Su Kim, Kyung-A Lee, Suk-Won Song","doi":"10.1093/icvts/ivag102","DOIUrl":"10.1093/icvts/ivag102","url":null,"abstract":"<p><strong>Objectives: </strong>To diagnose undiagnosed heritable thoracic aortic disease (HTAD) using targeted next-generation sequencing technology on human aorta tissue obtained from a single-centre biobank.</p><p><strong>Methods: </strong>From May 2016 to November 2021, 622 patients undergoing surgical repair for thoracic aortic aneurysm or acute aortic syndrome donated blood or tissue samples to the research biobank. A total of 134 aortic tissue samples were retrieved from patients suspected of HTAD. The inclusion criteria were (1) family history, (2) age ≤ 45, (3) annuloaortic ectasia, (4) bicuspid aortic valve, (5) patent ductus arteriosus, (6) polycystic kidney disease, or (7) patients previously classified as variant of uncertain significance by germline sequencing (n = 17). Exclusion criteria included patients previously classified as likely pathogenic or pathogenic by germline sequencing. The targeted panel included 96 genes.</p><p><strong>Results: </strong>A total of 29 variants were identified including FBN1, MYH11, COL11A1, SMAD3, SMAD6, ACTA2, COL3A1, FLNA, PKD2, THSD4, ACVRL1, and FBN2. A total of 27 patients (20.1%) had variants with 2 patients having digenic variants. Clinical data were combined with genetic data, and finally, 17 patients (12.7%) were additionally diagnosed with HTAD.</p><p><strong>Conclusions: </strong>Genomic data analysis of human aortic tissue allowed for additional diagnoses of undiagnosed HTAD, contributing to resolving discrepancies between clinical and genomic data. Considering the surgical treatment of HTAD, human aortic tissue can be a valuable resource for genomic analysis.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mid-term outcomes of titanium plate reconstruction for lung cancer requiring chest wall resection. 钛板重建术治疗胸壁切除肺癌的中期疗效。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-05-04 DOI: 10.1093/icvts/ivag131
Ryu Kanzaki, Shuhei Kobayashi, Daiki Hayashi, Kensuke Kojima, Toshiteru Tokunaga, Hyungeun Yoon
{"title":"Mid-term outcomes of titanium plate reconstruction for lung cancer requiring chest wall resection.","authors":"Ryu Kanzaki, Shuhei Kobayashi, Daiki Hayashi, Kensuke Kojima, Toshiteru Tokunaga, Hyungeun Yoon","doi":"10.1093/icvts/ivag131","DOIUrl":"https://doi.org/10.1093/icvts/ivag131","url":null,"abstract":"<p><strong>Objectives: </strong>Chest wall resection for non-small cell lung cancer (NSCLC) with chest wall invasion is rare and technically demanding, requiring complete resection and durable reconstruction. Although titanium-based devices are increasingly used, NSCLC-specific outcome data remain limited. We evaluated short- and mid-term outcomes of titanium plate-based chest wall reconstruction in NSCLC.</p><p><strong>Methods: </strong>We retrospectively reviewed 16 consecutive patients who underwent en bloc pulmonary and chest wall resection with titanium plate reconstruction for NSCLC between 2013 and 2019. Indications included resection of ≥ 3 ribs or anticipated instability. Reconstruction used perforated titanium plates tailored to defect geometry. Postoperative complications, late reconstruction-related events, and oncologic outcomes were analysed.</p><p><strong>Results: </strong>Preoperative therapy was administered in 8 patients (50%), including chemoradiotherapy in 7. R0 resection was achieved in 94%. Defects were predominantly posterior, with reconstruction adjacent to the scapula in 12 patients (75%). Thirty-day postoperative complications occurred in 9 patients (56%), consisting predominantly of pulmonary events. Postoperative chemotherapy was given to 6 patients (38%). During a median follow-up of 24 months (mean 54 months), two late complications occurred: chest wall haematoma and empyema. Only one chest wall local recurrence was observed. No structural failure or scapular impingement occurred. Five-year recurrence-free and overall survival rates were 35% and 63%, respectively.</p><p><strong>Conclusions: </strong>Titanium plate-based chest wall reconstruction enables extensive en bloc resection for NSCLC with chest wall invasion while maintaining mid-term structural stability. With appropriate patient selection and follow-up, this technique provides acceptable mid-term outcomes with durable structural stability.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The SurCOP procedure for ventricular septal rupture: analysis of outcomes and preoperative risk factors to guide surgical timing. SurCOP手术治疗室间隔破裂:结果和术前危险因素分析指导手术时机。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-04-30 DOI: 10.1093/icvts/ivag129
Chunxu Song, Nan Zhang, Jingtao Cao, Jiayi Guo, Jiayi Shi, Kaiwen Xiao, Chao Liu
{"title":"The SurCOP procedure for ventricular septal rupture: analysis of outcomes and preoperative risk factors to guide surgical timing.","authors":"Chunxu Song, Nan Zhang, Jingtao Cao, Jiayi Guo, Jiayi Shi, Kaiwen Xiao, Chao Liu","doi":"10.1093/icvts/ivag129","DOIUrl":"https://doi.org/10.1093/icvts/ivag129","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to explore the curative effect of Surgical repair Combining an Occluder and a Patch (SurCOP) procedure on postinfarction ventricular septal rupture and the related preoperative factors of death risk to assist clinical decision-making.</p><p><strong>Methods: </strong>This retrospective multicentre study included patients with postinfarction ventricular septal rupture who underwent Surgical repair Combining an Occluder and a Patch (SurCOP) procedure from 2017 to 2025. Preoperative variables were analyzed using univariable and multivariable logistic regression to identify independent risk factors for 30-day mortality.</p><p><strong>Results: </strong>A total of 60 patients were included. The 30-day mortality rate was 23.3%. Multivariable analysis identified older age (OR = 1.100, p = 0.032), higher preoperative creatinine (OR = 1.017, p = 0.017), and shorter time from acute myocardial infarction to surgery (OR = 0.894, p = 0.032) as independent risk factors. Mortality was highest (66.7%) when surgery occurred within 7 days of acute myocardial infarction, compared to 19.2% (7-14 days) and 17.8% (>14 days).</p><p><strong>Conclusions: </strong>The Surgical repair Combining an Occluder and a Patch procedure may enable earlier surgical intervention in patients with ventricular septal rupture. Given that advanced age, high preoperative creatinine, and a shorter acute myocardial infarction to surgery time are independent risk factors for early death, delaying surgery until around one-week post- acute myocardial infarction-when haemodynamically tolerated-is a strategy that may improve outcomes.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The NAVIGATE registry: Early endovascular repair of the ascending aorta with the nexus ascending module. 导航登记:早期血管内修复的升主动脉连接上升模块。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-04-30 DOI: 10.1093/icvts/ivag128
Víctor X Mosquera, Andrea Ferreiro, Said Abisi, Luis Riera, Alexander Maßmann, Arun Pherwani, José Garrido
{"title":"The NAVIGATE registry: Early endovascular repair of the ascending aorta with the nexus ascending module.","authors":"Víctor X Mosquera, Andrea Ferreiro, Said Abisi, Luis Riera, Alexander Maßmann, Arun Pherwani, José Garrido","doi":"10.1093/icvts/ivag128","DOIUrl":"https://doi.org/10.1093/icvts/ivag128","url":null,"abstract":"<p><strong>Objectives: </strong>Open repair remains the standard for ascending aortic pathology but carries high morbidity in frail or inoperable patients. This study evaluates the feasibility and early outcomes of endovascular repair using the Nexus Ascending Module, a CE-marked device designed for zone 0.</p><p><strong>Methods: </strong>NAVIGATE is a retrospective multicentre European registry including eight high-risk patients treated between 2023 and 2025 across six tertiary centres. All had focal zone 0 pathology and were deemed unsuitable for open repair. Procedures were planned with ECG-gated CT angiography and performed transfemorally. Technical success, perioperative complications, 30-day mortality, and follow-up outcomes were assessed.</p><p><strong>Results: </strong>Median age was 80.0 years (IQR: 59.5-80.5), and 87.5% had prior cardiac surgery. The median EuroSCORE II was 24.0% (IQR 19.7-44.0%). Pathologies included Contained rupture/pseudoaneurysm (n = 4), mycotic pseudoaneurysm (n = 3), and type A DeBakey II dissection (n = 1). Technical success was achieved in all patients; two required immediate overlapping stent-grafts for complete sealing. No stroke, valve dysfunction, coronary compromise, tamponade, type I/III endoleak, conversion to surgery, or in-hospital/30-day mortality occurred. One access-related complication was observed.Median ICU and hospital stays were 1 and 5 days. At a median follow-up of 15 months (IQR 12-24), no aortic reinterventions or device-related complications occurred. Two patients died from respiratory disease (12 months) and persistent infection (4 months).</p><p><strong>Conclusions: </strong>This small multicentre case series suggests that endovascular repair of isolated zone 0 ascending pathology using the Nexus Ascending Module is technically feasible in highly selected patients; however, these findings are preliminary and hypothesis-generating.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bacillus Calmette-Guérin related mycotic pseudoaneurysm in the aortic arch: clinical and surgical challenges. 卡介苗-谷氨酰胺相关真菌性假性动脉瘤在主动脉弓:临床和手术的挑战。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-04-24 DOI: 10.1093/icvts/ivag120
Sophie Bonni, Natasja W M Ramnath, Koen Selten, Ajay Moza
{"title":"Bacillus Calmette-Guérin related mycotic pseudoaneurysm in the aortic arch: clinical and surgical challenges.","authors":"Sophie Bonni, Natasja W M Ramnath, Koen Selten, Ajay Moza","doi":"10.1093/icvts/ivag120","DOIUrl":"https://doi.org/10.1093/icvts/ivag120","url":null,"abstract":"<p><p>Mycotic aortic aneurysms following intravesical Bacillus Calmette-Guérin (BCG) therapy for urothelial carcinoma are rare but life-threatening. A male patient with BCG-treated bladder cancer presented with syncope, cough, and fever. Computed tomography showed a distal arch pseudoaneurysm, and positron emission tomography indicated infection. Treatment included aortic arch and descending aorta replacement and antimicrobials. Histopathology confirmed Mycobacterium bovis infection. The patient died one month postoperatively due to stroke and organ failure. Early recognition and multidisciplinary management are crucial.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health-related quality of life and associated factors before and after coronary artery bypass grafting: A multicenter prospective study in cyprus. 冠状动脉旁路移植术前后与健康相关的生活质量及相关因素:塞浦路斯的一项多中心前瞻性研究
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-04-24 DOI: 10.1093/icvts/ivag126
Kyriakos Alexandrou, Nicos Middleton, Maria Kyranou, Pavlos Sarafis
{"title":"Health-related quality of life and associated factors before and after coronary artery bypass grafting: A multicenter prospective study in cyprus.","authors":"Kyriakos Alexandrou, Nicos Middleton, Maria Kyranou, Pavlos Sarafis","doi":"10.1093/icvts/ivag126","DOIUrl":"https://doi.org/10.1093/icvts/ivag126","url":null,"abstract":"<p><strong>Objectives: </strong>Coronary artery bypass grafting (CABG) improves survival in coronary artery disease (CAD), but its impact on health-related quality of life (HRQOL) remains variable. This study aimed to evaluate changes in HRQOL and associated factors before and after CABG.</p><p><strong>Methods: </strong>This prospective multicentre study, conducted across three hospitals in Cyprus, included patients undergoing elective CABG. HRQOL was assessed using the MacNew questionnaire preoperatively and at three and six months postoperatively. Associations with demographic and clinical factors, including age, gender, postoperative arrhythmias, left ventricular ejection fraction, and type of surgery, were examined. Non-parametric methods were applied due to non-normal data distribution.</p><p><strong>Results: </strong>HRQOL declined at three months compared with baseline (5.03 ± 1.02 vs 4.75 ± 1.00; p = 0.015), but improved significantly at six months (5.99 ± 0.67), exceeding preoperative levels. Male gender was associated with higher HRQOL scores at both follow-up time points (p = 0.011 and p = 0.009). No significant differences were observed by age, postoperative arrhythmia, left ventricular ejection fraction, or type of surgery.</p><p><strong>Conclusions: </strong>HRQOL declined early after CABG but improved significantly by six months, exceeding baseline levels. Male gender was associated with higher HRQOL scores. These findings support the value of incorporating HRQOL assessment into routine postoperative care.</p><p><strong>Trial registration: </strong>Thai Clinical Trials Registry (TCTR), ID: TCTR202247. URL: https://www.thaiclinicaltrials.org/.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical versus bioprosthetic conduits for the bentall procedure: a 10-year propensity score-matched analysis of early and long-term outcomes. 本特尔手术的机械导管与生物假体导管:早期和长期结果的10年倾向评分匹配分析。
Interdisciplinary cardiovascular and thoracic surgery Pub Date : 2026-04-22 DOI: 10.1093/icvts/ivag125
Emine Aleyna Eroglu Polat, Gokay Altaylı, Mehmet Okan Donbaloglu, Mucahit Polat
{"title":"Mechanical versus bioprosthetic conduits for the bentall procedure: a 10-year propensity score-matched analysis of early and long-term outcomes.","authors":"Emine Aleyna Eroglu Polat, Gokay Altaylı, Mehmet Okan Donbaloglu, Mucahit Polat","doi":"10.1093/icvts/ivag125","DOIUrl":"https://doi.org/10.1093/icvts/ivag125","url":null,"abstract":"<p><strong>Objectives: </strong>The optimal conduit choice for the Bentall procedure-mechanical (MC) or biological (BC)-is confounded by significant baseline selection bias. We aimed to evaluate the impact of conduit choice on early and long-term outcomes after mitigating this bias in a contemporary surgical cohort.</p><p><strong>Methods: </strong>We retrospectively reviewed 442 consecutive patients undergoing elective Bentall procedures between 2015 and 2025 (365 MC vs 77 BC). Propensity score matching (1:1 nearest-neighbor, caliper 0.1) was performed based on 10 baseline covariates (including age, EuroSCORE II, and comorbidities) to generate a balanced cohort of 154 patients (77 per group). Operative outcomes, 30-day morbidity/mortality, long-term overall survival, and reoperation-free survival were compared using paired statistical tests and Kaplan-Meier (Log-rank) analysis.</p><p><strong>Results: </strong>PSM successfully balanced baseline covariates, eliminating significant differences in age (mean 64.1 [MC] vs 65.7 [BC] years, p = 0.403) and EuroSCORE II (p = 0.698). The median follow-up was 36.0 months (IQR: 18.0-78.0). In the propensity-matched cohort, no significant differences were found in long-term overall survival (p = 0.574) or reoperation-free survival (p = 0.944) between the mechanical and biological groups. Early mortality was also comparable (p = 0.344). However, the biological group demonstrated a significantly higher rate of early re-exploration for bleeding (24.7% vs 6.5%, p = 0.003), associated with a 3.8-fold increased risk (OR: 4.72, 95% CI: 1.66-13.40).</p><p><strong>Conclusions: </strong>In this 10-year propensity-matched analysis, both mechanical and bioprosthetic conduits demonstrated comparable long-term durability and survival outcomes. Although biological conduits were associated with a higher risk of early re-exploration for bleeding, this did not adversely affect early mortality or long-term reoperation-free survival. These findings suggest that bioprosthetic conduits offer robust mid-term effectiveness, provided that meticulous intraoperative hemostasis is ensured to mitigate early bleeding risks.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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