Effect of patent complete revascularization on myocardium with persistent perfusion defects in preoperative single-photon emission computed tomography.

0 CARDIAC & CARDIOVASCULAR SYSTEMS
Min-Seok Kim, Joon Yeun Park, Seong Wook Hwang, Ki-Bong Kim
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Abstract

Objectives: This study aimed to evaluate the changes in perfusion assessed by myocardial single-photon emission computed tomography after coronary artery bypass grafting (CABG) and to examine the myocardial segments with persistent perfusion defect preoperatively in patients who underwent CABG and who had all patent grafts 1 year postoperatively.

Methods: Patients who underwent complete revascularization, who were assessed by preoperative and postoperative 3- and 12-month myocardial single photon emission computed tomography, and who showed all patent grafts on angiograms taken 1 year postoperatively were included. Myocardial single-photon emission computed tomography imaging was performed during stress and rest, and a 17-segment model was adopted for regional analysis of the perfusion defect. Myocardial segments were analysed based on a 5-point scale (0-4). After excluding the segments with normal stress scores, the difference scores (DSs) of the segments with impaired stress perfusion were calculated. The segments were divided into group P (DS ≤1) and group R (DS ≥2).

Results: Of 2057 myocardial segments from 120 patients, a total of 761 segments [segment group P (n = 572) vs segment group R (n = 189)] with impaired stress perfusion were included in the final analyses. The stress scores tended to decrease in both groups after the operation, although the changes in the stress perfusion scores over time were more significant in group R than in group P. The differences in the rest scores between groups P and R tended to decrease during postoperative year 1. Although the preoperative DSs were significantly lower in group P than in group R, the differences between the groups became insignificant during postoperative year 1.

Conclusions: Complete revascularization including myocardium with persistent perfusion defect should be considered when performing CABG.

术前单光子发射计算机断层扫描对持续灌注缺损心肌的影响。
目的:本研究旨在评价冠状动脉旁路移植术(CABG)后心肌单光子发射计算机断层扫描(cct)灌注的变化,并检查冠状动脉旁路移植术(CABG)患者术前持续灌注缺损的心肌节段和术后1年所有未移植的心肌节段。方法:纳入术前、术后3个月和12个月心肌单光子发射计算机断层扫描评估、术后1年血管造影显示移植物全部通畅的患者。在应激和休息时对心肌进行单光子发射计算机断层成像,采用17节段模型对灌注缺损进行区域分析。心肌段按5分制(0-4)进行分析。排除正常应激评分的节段后,计算应激灌注受损节段的差异评分(DSs)。将各节段分为P组(DS≤1)和R组(DS≥2)。结果:120例患者的2057个心肌节段中,共有761个节段[节段P组(n = 572) vs节段R组(n = 189)]被纳入最终分析。两组术后应激评分均有降低的趋势,但应激灌注评分随时间的变化R组较P组更为显著。术后1年P组与R组间的其余评分差异有减小的趋势。虽然P组术前DSs明显低于R组,但术后1年组间差异不显著。结论:冠状动脉搭桥应考虑完全血运重建,包括心肌持续灌注缺损。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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