Interdisciplinary cardiovascular and thoracic surgery最新文献

{"title":"Resectability and Neoadjuvant Chemoimmunotherapy in Stage II-III Non-Small Cell Lung Cancer: A European Case-Vignette Survey.","authors":"Savvas Lampridis, Akshay J Patel, Eleni Josephides, Fabian Doerr, Carmelina Cristina Zirafa, Seray Hazer, Andres Obeso, Ilies Bouabdallah, Monica Casiraghi, Andrea Billè","doi":"10.1093/icvts/ivag196","DOIUrl":"10.1093/icvts/ivag196","url":null,"abstract":"<p><strong>Objectives: </strong>Immunotherapy has expanded curative-intent options in non-small cell lung cancer (NSCLC), but management recommendations remain variable. This survey examined variation in resectability assessment and treatment sequencing among thoracic oncology clinicians managing stage II-III NSCLC.</p><p><strong>Methods: </strong>A web-based case-vignette survey was distributed to thoracic oncology clinicians, primarily in Europe. Seven stage II-III NSCLC vignettes, based on the ninth-edition TNM classification, were presented. Treatment options were recorded as independent yes/no endorsements. The primary outcome was endorsement of neoadjuvant chemoimmunotherapy among vignette evaluations considered resectable. Vignette-level binary outcomes were analysed using exploratory generalized estimating equations clustered by respondent.</p><p><strong>Results: </strong>Sixty-eight respondents provided vignette-level assessments. Resectability was generally endorsed in the N0/N1 and selected single-station N2 scenarios but was substantially lower in the multi-station and T3/T4 N2 scenarios. Among cases considered resectable, endorsement of neoadjuvant chemoimmunotherapy increased markedly in N2 scenarios, whereas cases considered unresectable were commonly associated with endorsement of concurrent chemoradiotherapy. In an exploratory model restricted to resectable-branch evaluations (249 observations from 57 respondents), any N2 involvement was associated with endorsement of neoadjuvant chemoimmunotherapy (adjusted odds ratio 28.42, 95% CI 7.31-110.42; P < .001), though the wide interval reflects the limited effective sample.</p><p><strong>Conclusions: </strong>Variation was greatest in borderline N2 disease, particularly multi-station and higher-T N2 scenarios, where clinicians diverged in defining resectability and in selecting surgery-based vs chemoradiotherapy-based pathways. These findings support the need for clearer multidisciplinary frameworks in stage II-III NSCLC, within the limits of a surgeon-weighted respondent pool and an anatomically focused vignette set.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13385344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148400234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Cannulation Strategies for Minimally Invasive Mitral Valve Surgery.","authors":"Juri Sromicki, Nestoras Papadopoulos, Lisa Tröbinger, Vasileios Ntinopoulos, Monika Hebeisen, Milan Milojevic, Hector Rodriguez Cetina Biefer, Omer Dzemali","doi":"10.1093/icvts/ivag185","DOIUrl":"10.1093/icvts/ivag185","url":null,"abstract":"<p><strong>Objectives: </strong>Minimally invasive mitral valve surgery (MIV-MVS) continues to evolve through refinements in surgical technique and perioperative management. This study evaluated the association between arterial cannulation strategy and perioperative adverse events.</p><p><strong>Methods: </strong>Three arterial cannulations were used: central ascending aortic cannulation (AC), open femoral cannulation via groin cutdown (oFC), and percutaneous femoral cannulation (pFC) using pre-closure devices. Patients from 2 centres were assessed for the composite safety end-point of 30-day mortality or stroke, the composite efficacy end-point of all-cause death, stroke, or cannulation-related adverse events, and postoperative delirium. Cannulation-related adverse events included conversion to sternotomy or re-thoracotomy, vessel dissection or bleeding, and cannulation-site infection.</p><p><strong>Results: </strong>Between January 2013 and January 2020, 823 patients underwent MIV-MVS. Aortic cannulation was performed in 266 patients (32.3%), oFC in 396 (48.1%), and pFC in 161 (19.6%). The composite end-point of 30-day all-cause death or stroke occurred in 19 patients (2.3%) and was similar between AC and FC (odds ratio [OR] 1.16, 95% CI, 0.41-3.16). The extended composite efficacy end-point occurred less frequently with AC than with any FC (OR 0.46, 95% CI, 0.21-0.94), mainly due to fewer access-site complications. Aortic cannulation was also associated with lower odds of perioperative delirium (OR 0.51, 95% CI, 0.29-0.86). No significant difference was observed between oFC and pFC.</p><p><strong>Conclusions: </strong>In patients undergoing MIV-MVS, 30-day death or stroke was similar across cannulation strategies. Aortic cannulation was associated with a lower rate of cannulation-related complications and less perioperative delirium than FC, largely reflecting fewer access-site complications. Further prospective external validation is warranted.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148371338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Status and Priorities of Valved Conduits for Right Ventricle-to-Pulmonary Artery Reconstruction in Japan: A Nationwide Survey.","authors":"Shintaro Nemoto, Hayato Konishi, Akiyo Suzuki, Takahiro Katsumata, Masaru Miura, Yusei Hamada, Yasumi Nishiwaki","doi":"10.1093/icvts/ivag177","DOIUrl":"10.1093/icvts/ivag177","url":null,"abstract":"<p><p>Right ventricle-to-pulmonary artery reconstruction is essential in congenital heart surgery. In Japan, cryopreserved homograft availability is limited, necessitating alternative materials. This study systematically elucidated the status of right ventricle-to-pulmonary artery conduit use and surgeon priorities in Japan. In 2024, a web-based nationwide survey was conducted by the Japanese Society of Paediatric Cardiology and Cardiac Surgery, targeting 126 institutions. We analysed data from 2021 to 2023 regarding primary diagnoses, conduit types, and selection criteria. Responses were obtained from 52 institutions (41.2%), covering 926 cases. Handmade expanded polytetrafluoroethylene valved conduits were most frequently used (80.7%), whereas bovine jugular vein conduits (7.5%) and homografts (1.1%) were rarely employed. \"Functional Durability and Performance\" was the most prioritized criterion (median score: 4.00), with a median expected durability of 10 years. We concluded that in Japan, where a homograft supply system is not established, handmade expanded polytetrafluoroethylene conduits are the primary choice despite their off-label status. A significant gap exists between current performance of conduits in general and clinical expectations for durability, underscoring the need for technological advancements in conduit design.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13324388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Related Long-Term Outcomes in On-Pump Coronary Artery Bypass Grafting-A Propensity Score-Matched Analysis.","authors":"Tim Knochenhauer, Friedrich Sobik, Jonas Pausch, Inken Detlef, Jens Brickwedel, Beate Reiter, Svante Zipfel, Yvonne Schneeberger, Hermann Reichenspurner, Evaldas Girdauskas, Bjoern Sill, Andreas Schaefer","doi":"10.1093/icvts/ivag186","DOIUrl":"10.1093/icvts/ivag186","url":null,"abstract":"<p><strong>Objectives: </strong>Coronary artery bypass grafting shows impaired outcomes in women compared to men. Investigation of sex-related outcome differences mostly comprises different operative strategies, potentially hampering interpretation of data. We herein aimed to investigate sex-related outcome differences in on-pump procedures only.</p><p><strong>Methods: </strong>All consecutive patients undergoing isolated on-pump bypass grafting between 2012 and 2021 at our centre were included in this study. Propensity score-matching was applied to compare outcomes of men and women. Kaplan-Meier analysis was used for investigating differences in survival probabilities. Identification of risk factors for long-term mortality was conducted by multivariable Cox regression.</p><p><strong>Results: </strong>In the matched cohort (326 pairs), women presented with a higher EuroSCORE II (European System for Cardiac Operative Risk Evaluation II) and less prior surgery. Distribution of arterial, venous, and radial bypass grafts was similar between sexes. Women presented more often with superficial wound healing disorders (P = .004), a higher amount of red blood cell transfusions (P < .001), and a longer hospital stay. Mortality at 30 days, 1 year, and 10 years revealed no difference between sexes (10-year mortality: men 27.7% vs women 22.6%; P = .228). Female sex was not significantly associated with long-term mortality.</p><p><strong>Conclusions: </strong>On-pump CABG in women is not associated with a higher prevalence of early or long-term all-cause mortality. Female sex is not a risk factor for long-term mortality. Women need more red blood cell transfusions, present with more superficial wound-healing disorders, and have a longer hospital stay. These findings underscore the overall safety of on-pump CABG in women.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148400224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extrapleural Approach for Thoracic Vertebral Stabilization.","authors":"Igor E Konstantinov, Vincent H Le, Michael B Johnson, Amine Mazine","doi":"10.1093/icvts/ivag161","DOIUrl":"10.1093/icvts/ivag161","url":null,"abstract":"<p><p>Surgical access to the upper thoracic vertebral bodies, defined as T1-T5, remains a technical challenge. The anterior extrapleural approach provides excellent visualization and access to the thoracic vertebrae; however, it remains a challenge due to the presence of the great vessels, sternum and trachea. Herein, we describe the case of a 16-year-old boy with avoidant/restrictive food intake disorder and autism spectrum disorder, who presented with lower limb paraparesis following a traumatic hyperflexion injury. Imaging revealed a T2 pathological burst fracture due to spinal haemangioma and osteopenia. Thoracic vertebral decompression and stabilization were performed through an anterior extrapleural approach using a median sternotomy combined with a lateral cervical incision. This approach provided excellent exposure of the anterior upper thoracic vertebral bodies.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Left Anterior Descending Artery Aneurysm With an Unusual Direct Continuity to the Aortic Arch.","authors":"Sahin Iscan, Erturk Karaagac, Serkan Yazman, Yuksel Besir","doi":"10.1093/icvts/ivag180","DOIUrl":"10.1093/icvts/ivag180","url":null,"abstract":"<p><p>A giant coronary artery aneurysm connected directly to the aortic arch is a rare and interesting cardiac pathology. When patients with coronary aneurysms and fistulas are not carefully investigated with advanced imaging techniques, surgeons may experience sudden problems intraoperatively, which may increase patients' morbidity. In this case report, we presented a surgical treatment and pre- and intraoperative surgical approaches to a patient with an interesting direct connection between a giant left anterior descending artery aneurysm and an aortic arch via a separate vessel, which was diagnosed thanks to a computed tomography scan, in a patient presenting with an acute myocardial infarction.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marked Response to Immunochemotherapy in Airway Mucosal Recurrence of Lung Squamous Cell Carcinoma.","authors":"Zijian Li, Chudong Wang, YenZhir Tay, Shuben Li","doi":"10.1093/icvts/ivag193","DOIUrl":"10.1093/icvts/ivag193","url":null,"abstract":"<p><strong>Objectives: </strong>Airway mucosal recurrence after complete resection of primary lung cancer is rare and lacks standard treatment. We aim to report a marked response to immunochemotherapy in a patient with multifocal airway mucosal recurrence of lung squamous cell carcinoma.</p><p><strong>Case description: </strong>A 50-year-old male patient presented with an irritative cough 2 years after right upper sleeve lobectomy for lung squamous cell carcinoma (SCC) (pT1bN0M0). Computed tomography and bronchoscopy revealed multiple recurrent polypoidal lesions in the trachea, with biopsy confirming recurrent SCC. After restaging and multidisciplinary evaluation, the patient was offered immunochemotherapy. The recurrent mucosal lesions exhibited a favourable response to the combination of a PD-1 inhibitor and chemotherapy.</p><p><strong>Conclusions: </strong>This case suggests a potentially effective strategy for high-risk patients with airway mucosal recurrence of lung squamous cell carcinoma.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13378447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Video-Assisted Transcervical-Transtracheal Repair for Post-Intubation Tracheal Laceration.","authors":"Chun-Han Shih, Chien-Wei Huang, Ting-Shou Chang","doi":"10.1093/icvts/ivag191","DOIUrl":"10.1093/icvts/ivag191","url":null,"abstract":"<p><strong>Background: </strong>Post-intubation tracheal laceration (PITL) is a rare but life-threatening complication. Early recognition and appropriate management are critical to prevent severe morbidity.</p><p><strong>Case presentation: </strong>A 30-year-old female with class III obesity (BMI: 41.8 kg/m²) presented with progressive subcutaneous emphysema and pneumomediastinum from a 3 cm full-thickness posterior tracheal laceration (Cardillo level IIIa) after orthopaedic surgery under general anaesthesia. On postoperative day 3, she underwent video-assisted transcervical-transtracheal repair via a temporary cervical tracheostomy. Utilizing a rigid endoscope and a protocol-driven, SpO2-guided intermittent apnoeic technique, the laceration was successfully repaired with a 3-0 Monocryl running suture without complications.</p><p><strong>Conclusions: </strong>The video-assisted transcervical-transtracheal approach offers a minimally invasive and effective alternative to conventional surgeries for PITL.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13394491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148377499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative C-Reactive Protein Resolution Patterns in Patients With and Without Postoperative Atrial Fibrillation After Cardiac Surgery.","authors":"Melina Heine, Felix Ulbrich, Samuel Justice, Babak Saravi, Simon A Amacher, Julian Hubrich, Leonard Simeth, Charles N Serhan, Jochen D Muehlschlegel, Jakob Wollborn","doi":"10.1093/icvts/ivag179","DOIUrl":"10.1093/icvts/ivag179","url":null,"abstract":"<p><strong>Objectives: </strong>Postoperative atrial fibrillation is common after cardiac surgery. Effective preventative measures are lacking, partly due to an incomplete understanding of its pathogenesis. Inflammation is a major contributor to postoperative atrial fibrillation development. This study aims to further characterize the association between systemic inflammation and postoperative atrial fibrillation.</p><p><strong>Methods: </strong>A secondary analysis was conducted on a single-center cohort of patients undergoing cardiac surgery. The original study enrolled 405 cardiac surgery patients. After exclusion of patients with a history of persistent or permanent atrial fibrillation, patients undergoing heart transplantation, and patients with incomplete interleukin measurements, 319 patients were included in the present analysis. Postoperative atrial fibrillation was identified through chart review and was defined as at least 1 AF episode lasting more than 30 s, as documented by telemetry or a 12-lead electrocardiogram during the patient's initial hospitalization. Perioperative levels of interleukins and C-reactive protein were measured. The decline in C-reactive protein levels between postoperative days 3 and 10 was modeled using a linear regression. The association with postoperative atrial fibrillation and other outcomes after cardiac surgery was assessed using logistic and Tobit regression models.</p><p><strong>Results: </strong>Of the 319 patients included in the study, 51% developed postoperative atrial fibrillation, most commonly on postoperative days 2 and 3. Cardiopulmonary bypass and intraoperative ventilation time were significantly associated with an increased risk of postoperative atrial fibrillation. Patients with postoperative atrial fibrillation had longer intensive care unit stays and longer times to extubation. C-reactive protein levels peaked on postoperative day 3 and declined more slowly in postoperative atrial fibrillation patients. A slower C-reactive protein decline was independently associated with postoperative atrial fibrillation (odds ratio: 1.71, P = .046), prolonged postoperative intensive care unit length of stay, and time to extubation. Interleukin-10 levels were significantly higher in patients with postoperative atrial fibrillation (mean ratio: 1.28, P < .001).</p><p><strong>Conclusions: </strong>Postoperative atrial fibrillation is a prevalent complication after cardiac surgery and correlates with a slower postoperative C-reactive protein decline. This study suggests that postoperative atrial fibrillation is associated with delayed resolution of postoperative inflammation.</p><p><strong>Trial registration number: </strong>German Clinical Trials Registry (DRKS No. 00017057), Date of registration April 5, 2019, www.drks.de.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally Invasive Valve Repair and Hybrid Treatment for Racemose Bronchial Artery Malformation With Coronary Arterial Inflow.","authors":"Makoto Matsuura, Toshiaki Ito, Satoshi Ariumura, Motoki Nagatsuka","doi":"10.1093/icvts/ivag202","DOIUrl":"10.1093/icvts/ivag202","url":null,"abstract":"<p><p>Racemose haemangioma of the bronchial artery is a rare vascular malformation characterized by abnormal communication between the bronchial and pulmonary vasculature. Coronary arterial inflow may further complicate minimally invasive cardiac surgery because excessive collateral flow can impair myocardial protection and increase intracardiac return during cardiac arrest. We report a case of atrial functional mitral regurgitation and tricuspid regurgitation associated with racemose bronchial artery malformation with coronary arterial inflow from the left circumflex artery. Preoperative embolization of systemic feeders from the bronchial and left subclavian arteries was followed by minimally invasive valve repair and surgical ligation of the coronary inflow vessel. The postoperative course was uneventful. A staged hybrid strategy may be effective for managing racemose bronchial artery malformation with coronary arterial inflow.</p>","PeriodicalId":73406,"journal":{"name":"Interdisciplinary cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}