Phytochemistry Reviews最新文献

{"title":"A comprehensive review on phytochemistry, pharmacology, preclinical, and clinical trials of Cydonia oblonga","authors":"Tuba,&nbsp;Muhammad Ajaz Hussain,&nbsp;Gulzar Muhammad,&nbsp;Muhammad Arshad Raza,&nbsp;Adnan Ashraf,&nbsp;Muhammad Tahir Haseeb,&nbsp;Muhammad Mushtaq,&nbsp;Zahid Shafiq","doi":"10.1007/s11101-024-09946-8","DOIUrl":"10.1007/s11101-024-09946-8","url":null,"abstract":"<div><p><i>Cydonia oblonga</i> M. (Quince), a deciduous shrub from the family <i>Rosaceae</i>, has been recognized in the last decade mainly because of its potential to prevent/cure cancer, high cholesterol, blood sugar, chronic stress, peptic ulcer, liver injuries, asthma, and various fertility disorders. Several metabolites, including flavonoids, phenolic acids, polyphenols, carotenoids, lignans, stilbenes, triterpenoids, procyanidins, glycosides, and organic acids, have been identified as the major phytochemical components. Different parts of <i>C. oblonga</i> are known to demonstrate a broad spectrum of biological activities against numerous microbial infections, free radicals-mediated damages, cancer cells proliferation, lipid profile dysfunction, glucose metabolism disorder, lethal oxalocalcic kidney stones, hydatid cysts of protoscolices, and inflammatory diseases. In preclinical trials, neuro-protective, anti-hyperglycemic, anti-hyperlipidemic, anti-inflammatory, and wound healing activities and protective effects on hepatocellular carcinoma, testicular tissue alteration, endocrine disruption, cardiotoxicity, depression, and blood pressure have been investigated for the valuable plant. The clinical studies explore the plant's potential to treat reproductive, respiratory, and gastrointestinal disorders and support using <i>C. oblonga</i> as a new herbal medicine. However, additional research is needed to unravel its intricate action mechanisms, evaluate safe dosing strategies, identify any adverse effects, and validate its pharmacological effects in a broad population over a longer timeframe before approving it as a new herbal treatment. In conclusion, the review presents detailed analyses of the phytochemistry, pharmacology, preclinical, and clinical trials of <i>C</i>. <i>oblonga</i>.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"24 1","pages":"85 - 118"},"PeriodicalIF":7.3,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140324839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular targeting of constituents of commonly used spices and its molecular interactions in endothelial dysfunction: A review","authors":"Pronay Mandal,&nbsp;S. K. Kanthlal","doi":"10.1007/s11101-024-09939-7","DOIUrl":"10.1007/s11101-024-09939-7","url":null,"abstract":"<div><p>Endothelial dysfunction, characterized by impaired endothelial function, is critical in developing cardiovascular diseases. Emerging evidence suggests that certain constituents of commonly used spices potentially mitigate endothelial dysfunction. This review summarizes the current literature on the constituents of commonly used spices and their molecular interactions in endothelial system. We first provide an overview of physiological significance as well as dysfunction of endothelium and its role in cardiovascular diseases, including the mechanisms like oxidative stress, inflammation, atherosclerosis, hypertension, thrombosis, and impaired nitric oxide (NO) bioavailability. The physiological significance such as, regulation of thrombosis and fibrinolysis, preventing atherosclerosis and neo-angiogenesis, were discussed. Various spices reported to possess vascular-targeting properties, including curcumin from turmeric, allicin from garlic, gingerol from ginger, piperine from black pepper, quercetin from onion, 2-methoxycinnamaldehyde from cinnamon etc. were discussed. We highlight the molecular interactions of these spice constituents with endothelial cells, including their effects on oxidative stress, inflammation, atherosclerosis, thrombosis, and NO bioavailability. Evidence from in vitro, animal, and human studies reveals that, spice constituents modulate various signaling pathways and enhance NO bioavailability, which collectively contribute to their potential beneficial effects on endothelial function. Furthermore, we discuss the potential mechanisms including reduced expression of ICAM, VCAM, and selectin, inhibition of NF-κB activation and translocation, and decreased ROS and H₂O₂ levels. In conclusion, the constituents of commonly used spices, such as (allicin, curcumin, quercetin, gingerol etc.) promises a novel approach for modulating endothelial function in vascular disorders. Further research in this area may provide valuable insights into the potential use of these spice constituents as complementary or alternative therapies for cardiovascular diseases.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 6","pages":"1805 - 1834"},"PeriodicalIF":7.3,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140325127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advancements in natural compounds for cancer therapy and prevention","authors":"R. Pavithra,&nbsp;Mohammad Rashid Khan,&nbsp;Mohd Shahanbaj Khan","doi":"10.1007/s11101-024-09940-0","DOIUrl":"10.1007/s11101-024-09940-0","url":null,"abstract":"<div><p>Even after a century of substantial advancements in oncology medicines, cancer still ranks as one of the top causes of death worldwide. As a result, there is an ongoing and pressing need for the development of new cancer drugs. Natural compounds and their semi-synthetic derivatives continue to show promise as potential therapeutic leads, due to their high chemical diversity, biochemical specificity, significant molecular activities, and pharmacological properties. They serve as excellent starting points for the discovery of new drugs, inspiring new breakthroughs in biology, chemistry, and medicine. In recent years, scientists have made significant advancements in the development of naturally occurring or partly synthesized analogues with improved bioactivity, simpler synthetic targets and reduced toxicity. This review aims to summarize the importance and biological actions of natural compounds identified form plants and their role in prevention of cancer treatment.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 6","pages":"1835 - 1859"},"PeriodicalIF":7.3,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140325129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glucosinolates, isothiocyanates, and their role in the regulation of autophagy and cellular function","authors":"Paola Maycotte,&nbsp;Marcelo Illanes,&nbsp;Diego A. Moreno","doi":"10.1007/s11101-024-09944-w","DOIUrl":"10.1007/s11101-024-09944-w","url":null,"abstract":"<div><p>Autophagy is a cellular degradation process important for the maintenance of cytoplasmic integrity which can be upregulated in response to stress which is active in eukaryotic cells. Promotion of autophagy has been related to lifespan expansion, tumor suppression and the maintenance of metabolic health. Also, alterations in this pathway have been related to human diseases or pathological states including neurodegenerative diseases, stroke, metabolic alterations, or cancer. Extensive research on the effects of natural products on autophagy has been made, with a particular focus on phenolic compounds. However, plant nitrogen-containing specialized metabolites have recently acquired great importance due to their potential therapeutic uses. Among these, glucosinolates (GSL), a group of thioglucosides and their bioactive metabolites, isothiocyanates (ITC) and indoles, are known to modulate cellular processes important for disease treatment and prevention. These compounds are almost exclusive of cruciferous foods (Brassicas), including broccoli, cabbages, radishes, kale, mustards, rocket salad or arugula, wasabi, and so on. The cruciferous vegetables are widely distributed worldwide and highly consumed in Europe, Asia and the Americas. Due to the important role of autophagy as a cellular homeostatic maintenance process, and its alterations in pathological states, we reviewed the recent evidence relating the effects of GSL metabolites and their role as modulators of autophagy. The potential to modulate this process is crucial for the maintenance of human health and to treat highly prevalent diseases where autophagy is involved, such as neurodegenerative, metabolic disorders, or cancer.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"24 1","pages":"49 - 83"},"PeriodicalIF":7.3,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140324835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aldoximes: compounds at the crossroads of multiple metabolic pathways in plant","authors":"Doosan Shin,&nbsp;Veronica C. Perez,&nbsp;Jeongim Kim","doi":"10.1007/s11101-024-09950-y","DOIUrl":"10.1007/s11101-024-09950-y","url":null,"abstract":"<div><p>Aldoximes are amino acid-derivatives well recognized as precursors of defense compounds, such as glucosinolates and cyanogenic glycosides. However, recent studies have elucidated the multifaceted roles of aldoximes in plant survival beyond defense, as they exert influence over multiple metabolic pathways, including auxin biosynthesis and the phenylpropanoid pathway. Aldoxime accumulation affects the homeostasis of auxin, an essential plant hormone that controls almost every aspect of plant growth and development. While auxin biosynthesis primarily occurs through the conserved TAA/YUC pathway, tryptophan-derived aldoxime and phenylalanine-derived aldoxime also serve as precursors of two major auxins, indole-3-acetic acid (IAA) and phenylacetic acid (PAA), respectively. Notably, this conversion process is not limited to Brassicales and is present in monocots like maize and sorghum. Furthermore, in Brassicales, the accumulation of aldoximes derived from aliphatic and aromatic amino acids represses the phenylpropanoid pathway that produces an array of specialized metabolites crucial for plant survival. These novel findings extend beyond the conventional understanding of aldoximes and shed light on their intricate involvement in enhancing plant fitness. In this review, we discuss the role of aldoximes as precursors for auxins and their inhibitory effect on phenylpropanoid biosynthesis. We also explore the mechanisms by which aldoximes influence these metabolic pathways. Finally, we discuss the implications of these findings for our understanding of plant biology.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"24 1","pages":"37 - 47"},"PeriodicalIF":7.3,"publicationDate":"2024-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140299443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asclepiadoideae subfamily (Apocynaceae): ethnopharmacology, biological activities and chemophenetics based on pregnane glycosides","authors":"Thalisson Amorim de Souza,&nbsp;Francisca Sabrina Vieira Lins,&nbsp;Jociano da Silva Lins,&nbsp;Alan Ferreira Alves,&nbsp;Samuel Paulo Cibulski,&nbsp;Brito Thiago de Araújo Medeiros,&nbsp;Lucas Silva Abreu,&nbsp;Luciana Scotti,&nbsp;Marcus Tullius Scotti,&nbsp;Marcelo Sobral da Silva,&nbsp;Josean Fechine Tavares","doi":"10.1007/s11101-024-09914-2","DOIUrl":"10.1007/s11101-024-09914-2","url":null,"abstract":"<div><p>Apocynaceae, one of the largest plant families with over 5.100 widely distributed species, serves as a significant model for evolutionary and biochemical studies. Within this family, compounds such as alkaloids, flavonoids, and terpenoids with potential therapeutic activities have been isolated. Among its subfamilies, Asclepiadoideae is recognized as a rich source of C₂₁ pregnane derivatives. This paper presents a comprehensive review of pregnane glycosides (PG) obtained from Asclepiadoideae, employing an interdisciplinary approach that combines chemophenetics with neural network data analysis to identify promising species and bioactive compounds. A dataset comprising 660 unique PGs and 705 botanical occurrences was compiled for this purpose. The ethnopharmacological aspects, as well as the extraction, isolation, and biological activity of PGs, were analyzed and discussed. Chemophenetic analysis using Self-Organizing Maps (SOM) and phylogeny reconstruction revealed similarities between the Marsdenia-Ceropegiae tribes and highlighted the occurrence of seco and diseco pregnane types predominantly within the Asclepiadeae tribe. Both scaffolds exhibited intriguing structural features, and their derivatives have demonstrated anti-inflammatory and cytotoxic activities. These findings provide valuable insights for future research on these compounds and their medicinal plant sources.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 4","pages":"1027 - 1063"},"PeriodicalIF":7.3,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140201195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrients and polyphenols-rich Sorghum bicolor genotypes as complementary therapy for Alzheimer’s disease","authors":"Rasheed A. Abdulraheem,&nbsp;Ralph N. Martins,&nbsp;Prashant Bharadwaj,&nbsp;Zhaoyu Li,&nbsp;Ranil Coorey,&nbsp;Stuart Johnson,&nbsp;W. M. A. D. Binosha Fernando","doi":"10.1007/s11101-024-09942-y","DOIUrl":"10.1007/s11101-024-09942-y","url":null,"abstract":"<div><p>Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and most common cause of dementia among older people. The main pathological hallmarks of AD are formation of insoluble amyloid beta senile plaques and paired helical filaments of neurofibrillary tangles. AD features gradual memory decline, mild to severe cognitive impairment, eventually total dependence of patients on caregivers. Currently available drugs have not been able to modify AD pathology. This has drawn increasing attention to plant food materials with high nutritional and bioactive constituents as potential complementary therapy for AD. <i>Sorghum bicolor</i> is a widely available cost-effective source of proteins, fats, crude fibres, biopeptides and polyphenols which are vital for human wellbeing. This review discussed the major mechanisms underlying AD pathology. The nutritional and bioactive constituents of <i>Sorghum bicolor</i> grains were extensively described. There is limited report on anti-AD activities of sorghum grains. Therefore, the pharmacological mechanisms of action including scavenging of reactive oxygen species, inhibition of oxidative stress, anti-acetylcholinesterase activity and modulation of mitophagy were only speculated. This comprehensive update suggests more robust innovative studies that will provide critical theoretical details necessary to promote utilization of sorghum grains as functional food or source of bioactive molecules for AD therapy.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 6","pages":"1889 - 1912"},"PeriodicalIF":7.3,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11101-024-09942-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140201109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling role of crocin for the treatment of Alzheimer’s and Parkinson’s disease: sojourn from food to nanomedicine","authors":"Harmanpreet Kaur,&nbsp;Bushra Bashir,&nbsp;Amandeep Kaur,&nbsp;Navneet Singh,&nbsp;Sukriti Vishwas,&nbsp;Puneet Kumar,&nbsp;Harish Dureja,&nbsp;Motamarri Venkata Naga Lalitha Chaitanya,&nbsp;Thakur Gurjeet Singh,&nbsp;Gaurav Gupta,&nbsp;Aftab Alam,&nbsp;Francisco Veiga,&nbsp;Ana Cláudia Paiva-Santos,&nbsp;Kamal Dua,&nbsp;Sachin Kumar Singh","doi":"10.1007/s11101-024-09936-w","DOIUrl":"10.1007/s11101-024-09936-w","url":null,"abstract":"<div><p>Flavonoids have a longstanding tradition of being employed in traditional medicine to improve human health. Crocin has been suggested as a potential candidate for addressing a range of ailments, including neurodegenerative diseases (NDs). In the modern era, diverse pharmacological activities of crocin have been explored due to its bioactive constituents like kaempferol, picrocrocin, safranal, and crocetin. It demonstrates pharmacological and therapeutic efficacy against various diseases such as cancer, kidney diseases, NDs, and measles, attributable to several mechanisms. Various studies evidence that it exerts a neuroprotective effect in conditions like Alzheimer’s disease, Parkinson's disease, Huntington's disease, Amyotrophic lateral sclerosis, and others, by modulating relevant parameters. Despite harboring numerous pharmacological benefits, it exhibits low bioavailability due to poor solubility and limited ability to cross the blood–brain barrier (BBB). To address this issue, diverse approaches involving nanoformulations have been developed to enhance their bioavailability, aqueous solubility, and BBB permeability. Various types of studies have been conducted on crocin-loaded nanoparticles against NDs, which are discussed in this paper.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 6","pages":"1737 - 1760"},"PeriodicalIF":7.3,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140201192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyamines: defeat or survival of the fungus","authors":"Beata Augustyniak,&nbsp;Yelyzaveta Kochneva,&nbsp;Jan Widuła,&nbsp;Anna Kulma","doi":"10.1007/s11101-024-09937-9","DOIUrl":"10.1007/s11101-024-09937-9","url":null,"abstract":"<div><p>Polyamines are low molecular weight amines that serve numerous pivotal functions in eukaryotic cells, such as contributing to processes like embryogenesis, organogenesis in plants, and host interactions in fungi. Over the years, there has been significant interest in these compounds concerning the enhancement of plant resistance to pathogenic infections. As polyamines play indispensable roles in both plant and fungal functionalities, elucidating their precise significance in the interplay between these two organisms remains intricate. Furthermore, it is becoming evident that polyamines can yield disparate effects contingent upon factors such as prevailing conditions, concentrations, and the specific species of both plants and fungi.</p><p>This paper provides an analysis of recent research conducted mostly within the last five years, concentrating on the multifaceted role of polyamines in the dynamic between plants and two types of fungi: phytopathogenic and mycorrhizal. The investigation places particular emphasis on two principal aspects. Firstly, it delves into the influence of polyamines on fungal pathogens, encompassing aspects such as mycotoxin production and the infection process. Secondly, it explores the intricate interplay of the plant's immune response to fungal pathogens.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 6","pages":"1761 - 1774"},"PeriodicalIF":7.3,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140205591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental, industrial, and health benefits of Moringa oleifera","authors":"Harshika Mahaveerchand,&nbsp;Abdul Ajees Abdul Salam","doi":"10.1007/s11101-024-09927-x","DOIUrl":"10.1007/s11101-024-09927-x","url":null,"abstract":"<div><p>The rise of air, water, and soil pollution poses a significant threat to global health, leading to widespread disease and premature mortality. Soil health is vital, ensuring the production of safe food, but it is compromised by pollutants such as heavy metals, pesticides, plastics, and excessive fertilization, resulting in the depletion of beneficial microorganisms and subsequently groundwater contamination. Water bodies are polluted due to contamination from industrial effluents, domestic wastewater, agricultural runoff, and oil spillage, further intensifying environmental pollution. On the other hand, atmospheric pollution, characterized by high emissions of gases, volatile compounds, greenhouse gases, not only impacts the climate but also poses serious risks to human health, leading to respiratory diseases, cardiovascular issues, and increased cancer risks. Thus, the strategic utilization of traditional plants emerges as a potent tool for environmental restoration and improving human health. The plants possess natural filtering capabilities, absorbing pollutants from air, soil, and water, thus mitigating their adverse effects. Through phytoremediation, plants can be actively used to extract and remove contaminants, contributing to detoxification and improving water and soil quality. Additionally, plants offer various health benefits. <i>Moringa oleifera</i> or the drumstick plant belonging to the <i>Moringaceae</i> family is one such indigenous plant with wide applications, that can be grown in extreme arid conditions. Since ancient times, this plant has been used for treating skin infections, anaemia, and blood impurities. This plant thrives in diverse climates addressing over 300 different aliments. Rich in phytochemicals and bioactive compounds, <i>M. oleifera</i> serve as a superfood, offering high nutritional values and exhibiting potential for drug development with fewer side effects. Extensive research has elucidated the diverse properties and applications of <i>M. oleifera</i>, however, in-depth research is needed to identify bioactive molecules, phytochemicals, and protein compounds involved, which will aid in understanding of the mechanisms of action of the plant's diverse functions. Although studies have reported several of individual <i>M. oleifera</i> attributes<i>,</i> there is no comprehensive study available addressing its diverse applications. This review covers the findings of past three decades and provides a detailed outline of <i>M. oleifera</i> plant and its various parts, its applications in environmental, industrial, food and health aspects documented to date.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 5","pages":"1497 - 1556"},"PeriodicalIF":7.3,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11101-024-09927-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140146534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}