Phytochemistry Reviews最新文献

{"title":"Guest editorial: special issue on “Microalgae biorefinery: current bottlenecks, challenges, and future directions”","authors":"Pau-Loke Show, Young-Kwon Park, Sulaiman Al-Zuhair, Veeramuthu Ashokkumar","doi":"10.1007/s11101-023-09881-0","DOIUrl":"10.1007/s11101-023-09881-0","url":null,"abstract":"","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 4","pages":"829 - 831"},"PeriodicalIF":7.7,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4749092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing wastewater and flue gas for enhancing biomass and high-value products from microalgae","authors":"Jaemin Joun,&nbsp;Ranjna Sirohi,&nbsp;Byung Sun Yu,&nbsp;Ha Eun Yang,&nbsp;Sang Jun Sim","doi":"10.1007/s11101-023-09876-x","DOIUrl":"10.1007/s11101-023-09876-x","url":null,"abstract":"<div><p>Microalgae cultivation using wastewater has been conducted to treat wastewater and lower carbon footprints. Wastewater can contribute to microalgae culture by supplying nutrients such as nitrogen, phosphorus, and organic carbon sources. Meanwhile, greenhouse gas emissions from fossil fuel consumption are also increasing rapidly, and global warming is intensifying. To overcome this phenomenon, Carbon Capture, Utilization, and Storage technology, a highly efficient greenhouse gas treatment technology that can capture and separate CO₂, has been developed and comprehensively discussed in this review. As a technology for capturing carbon, microalgae are cultured by supplying high concentrations of CO₂ using industrial flue gas. In addition, microalgae are used for removing organic substances, phosphorus, and nitrogen in wastewater. Through such biological treatment processes, it is possible to simultaneously reduce CO₂, remove biocontaminants, and produce high-value-added substances. Recently, research has been conducted on promoting microalgae growth by supplying wastewater and flue gas by enabling mixotrophic cultivation of microalgae. The review finally provides that sewage and industrial flue gas have the potential to improve the productivity of microalgae, reduce cost, and encourage environmental sustainability.</p><h3>Graphical abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 4","pages":"861 - 877"},"PeriodicalIF":7.7,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4427623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chimaphila umbellata; a biotechnological perspective on the coming-of-age prince’s pine","authors":"Urooj Ali,&nbsp;Muhammad Mustajab Khan,&nbsp;Naveera Khan,&nbsp;Rida tul Haya,&nbsp;Muhammad Usama Asghar,&nbsp;Bilal Haider Abbasi","doi":"10.1007/s11101-023-09880-1","DOIUrl":"10.1007/s11101-023-09880-1","url":null,"abstract":"<div><p><i>Chimaphila umbellata</i> has been studied for almost two centuries now, with the first paper exploring the phytochemistry of the plant published in 1860. Almost all contemporary studies focus on the biotechnological advances of <i>C. umbellata</i> including its utilization as a natural alternative in the cosmetic, food, biofuel, and healthcare industry, with a special focus on its therapeutic uses. This literature review critically investigates the significance and applications of secondary metabolites extracted from the plant and presses on the biotechnological approaches to improve its utilization. <i>C. umbellata</i> is home to many industrially and medicinally important phytochemicals, the majority of which belong to phenolics, sterols, and triterpenoids. Other important compounds include 5-hydroxymethylfurfural, isohomoarbutin, and methyl salicylate (the only essential oil of the plant). <i>Chimaphilin</i> is the characteristic phytochemical of the plant. This review focuses on the phytochemistry of <i>C. umbellata</i> and digs into their chemical structures and attributes. It further discusses the challenges of working with <i>C. umbellata</i> including its alarming conservation status, problems with <i>in-vitro</i> cultivation, and research and development issues. This review concludes with recommendations based on biotechnology, bioinformatics, and their crucial interface.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 1","pages":"229 - 244"},"PeriodicalIF":7.3,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10298533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flavonoids in major cereal grasses: distribution, functions, biosynthesis, and applications","authors":"Lydia Pui Ying Lam,&nbsp;Lanxiang Wang,&nbsp;Andy C. W. Lui,&nbsp;Hongjia Liu,&nbsp;Toshiaki Umezawa,&nbsp;Yuki Tobimatsu,&nbsp;Clive Lo","doi":"10.1007/s11101-023-09873-0","DOIUrl":"10.1007/s11101-023-09873-0","url":null,"abstract":"<div><p>Cereal food crops like maize (<i>Zea mays</i>), rice (<i>Oryza sativa</i>), sorghum (<i>Sorghum bicolor</i>) and wheat (<i>Triticum aestivum</i>) are members of the grass family (Poaceae). Together with bioenergy grasses, they play essential roles in agriculture and biorefinery, comprising an important component of bio-economy. Grasses accumulate a unique range of flavonoids (a class of plant-specific specialized metabolites) that contribute to defense responses, fertility, pigmentation and cell wall lignification. This review summarizes the distribution, functions, biosynthesis and regulation of flavonoids, including flavanones, tricin and flavone <i>O</i>-conjugates, flavone <i>C</i>-glycosides, 3-deoxyanthocyanidins, phlobaphenes, anthocyanins, proanthocyanidins (condensed tannins) and flavonols, in grasses focusing on model cereal grasses. In particular, the constitutive, predominant and widespread tricin-lignin, flavone <i>O</i>-conjugates and flavone <i>C</i>-glycosides as well as the inducible and/or lineage-specific sakuranetin (a flavanone), maysin (a flavone <i>C</i>-glycoside), 3-deoxyanthocyanidins and phlobaphenes, are highlighted. Finally, the impacts and importance of cereal grass flavonoids on scientific research, agricultural production, food and health, and biorefinery are discussed.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 5","pages":"1399 - 1438"},"PeriodicalIF":7.7,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41083965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Garcinia kola: a critical review on chemistry and pharmacology of an important West African medicinal plant","authors":"Jan Tauchen,&nbsp;Adela Frankova,&nbsp;Anna Manourova,&nbsp;Irena Valterova,&nbsp;Bohdan Lojka,&nbsp;Olga Leuner","doi":"10.1007/s11101-023-09869-w","DOIUrl":"10.1007/s11101-023-09869-w","url":null,"abstract":"<div><p><i>Garcinia kola</i> Heckel (Clusiaceae) is a tree indigenous to West and Central Africa. All plant parts, but especially the seeds, are of value in local folklore medicine. <i>Garcinia kola</i> is used in treatment of numerous diseases, including gastric disorders, bronchial diseases, fever, malaria and is used to induce a stimulating and aphrodisiac effect. The plant is now attracting considerable interest as a possible source of pharmaceutically important drugs. Several different classes of compounds such as biflavonoids, benzophenones, benzofurans, benzopyran, vitamin E derivatives, xanthones, and phytosterols, have been isolated from <i>G. kola</i>, of which many appears to be found only in this species, such as garcinianin (found in seeds and roots), kolanone (fruit pulp, seeds, roots), gakolanone (stem bark), garcinoic acid, garcinal (both in seeds), garcifuran A and B, and garcipyran (all in roots). They showed a wide range of pharmacological activities (e.g. analgesic, anticancer, antidiabetic, anti-inflammatory, antimalarial, antimicrobial, hepatoprotective and neuroprotective effects), though this has only been confirmed in animal models. Kolaviron is the most studied compound and is perceived by many studies as the active principle of <i>G. kola</i>. However, its research is associated with significant flaws (e.g. too high doses tested, inappropriate positive control). Garcinol has been tested under better conditions and is perhaps showing more promising results and should attract deeper research interest (especially in the area of anticancer, antimicrobial, and neuroprotective activity). Human clinical trials and mechanism-of-action studies must be carried out to verify whether any of the compounds present in <i>G. kola</i> may be used as a lead in the drug development.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 5","pages":"1305 - 1351"},"PeriodicalIF":7.7,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11101-023-09869-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41084226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemistry, data mining, pharmacology, toxicology and the analytical methods of Cyperus rotundus L. (Cyperaceae): a comprehensive review","authors":"Bian-Xia Xue,&nbsp;Ru-Shang He,&nbsp;Jia-Xin Lai,&nbsp;Nana Ama Mireku-Gyimah,&nbsp;Li-Hua Zhang,&nbsp;Hong-Hua Wu","doi":"10.1007/s11101-023-09870-3","DOIUrl":"10.1007/s11101-023-09870-3","url":null,"abstract":"<div><p><i>Cyperus rotundus</i> L. has been widely used in the treatment and prevention of numerous diseases in traditional systems of medicine around the world, such as nervous, gastrointestinal systems diseases and inflammation. In traditional Chinese medicine (TCM), its rhizomes are frequently used to treat liver disease, stomach pain, breast tenderness, dysmenorrheal and menstrual irregularities. The review is conducted to summarize comprehensively the plant’s vernacular names, distribution, phytochemistry, pharmacology, toxicology and analytical methods, along with the data mining for TCM prescriptions containing <i>C. rotundus</i>. Herein, 552 compounds isolated or identified from <i>C. rotundus</i> were systematically collated and classified, concerning monoterpenoids, sesquiterpenoids, flavonoids, phenylpropanoids, phenolics and phenolic glycosides, triterpenoids and steroids, diterpenoids, quinonoids, alkaloids, saccharides and others. Their pharmacological effects on the digestive system, nervous system, gynecological diseases, and other bioactivities like antioxidant, anti-inflammatory, anti-cancer, insect repellent, anti-microbial activity, etc. were summarized accordingly. Moreover, except for the data mining on the compatibility of <i>C. rotundus</i> in TCM, the separation, identification and analytical methods of <i>C. rotundus</i> compositions were also systematically summarized, and constituents of the essential oils from different regions were re-analyzed using multivariate statistical analysis. In addition, the toxicological study progresses on <i>C. rotundus</i> revealed the safety property of this herb. This review is designed to serve as a scientific basis and theoretical reference for further exploration into the clinical use and scientific research of <i>C. rotundus</i>.\u0000</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 5","pages":"1353 - 1398"},"PeriodicalIF":7.7,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41083927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabis monoterpene synthases: evaluating structure–function relationships","authors":"B. Markus Lange,&nbsp;Narayanan Srividya","doi":"10.1007/s11101-023-09861-4","DOIUrl":"10.1007/s11101-023-09861-4","url":null,"abstract":"<div><p>Terpene synthases catalyze the first committed step in the biosynthesis of terpenes, a structurally diverse class of natural products that also encompasses volatiles derived from precursors in the C10 to C15 range (termed monoterpenes and sesquiterpenes, respectively). In the review section of this article, we are providing information about all functionally characterized monoterpene synthases (MTSs) and sesquiterpene synthases (STSs) of <i>Cannabis sativa</i> L. We are also exploring the locations of MTSs and STSs in the chromosome-level assembly of the reference chemovar CBDRx. A follow-up computational structure–function analysis focuses on MTSs, as there is already a rich literature available on the topic. More specifically, by employing sequence comparisons and homology structural modeling, we infer which amino acid residues are likely to constrain the available space in the active site of cannabis MTSs. The emphasis of these studies was to investigate why some MTSs accept only a C10 diphosphate as substrate, while mixed MTS/STS enzymes also accommodate a C15 diphosphate. By combining a literature review and computational analyses in a hybrid format, we are laying the foundation for future studies to better understand the determinants of substrate and product specificity in these fascinating enzymes.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 2","pages":"449 - 465"},"PeriodicalIF":7.7,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4148086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of exogenously applied antioxidants on plant growth and resilience","authors":"Aline Rodrigues de Queiroz,&nbsp;Connor Hines,&nbsp;Jeremy Brown,&nbsp;Seema Sahay,&nbsp;Jithesh Vijayan,&nbsp;Julie M. Stone,&nbsp;Nate Bickford,&nbsp;Melissa Wuellner,&nbsp;Katarzyna Glowacka,&nbsp;Nicole R. Buan,&nbsp;Rebecca L. Roston","doi":"10.1007/s11101-023-09862-3","DOIUrl":"10.1007/s11101-023-09862-3","url":null,"abstract":"<div><p>Plant growth and resilience require balancing an inherently oxidative metabolism with powerful antioxidant systems that help maintain homeostasis. When the environment changes, reactive oxygen species are potent indicators of that change, allowing adaptation through re-balancing metabolism and antioxidant systems. A large body of evidence supports the use of exogenously applied antioxidants to improve both plant growth and their resilience to stress. Notably, some phenotypic effects are similar upon the application of chemically diverse antioxidants, while others are distinct. In this review, we analyze research from antioxidant treatment experiments and highlight the similarities in their practical applications and their effects on plant stress tolerance, photosynthesis, native antioxidant systems, and phytohormones. We also briefly cover the specific effects of individually applied antioxidants and what is known about their potential modes of action. Given the strong potential of antioxidant applications, we discuss research needed to promote their agricultural use. Finally, we identify outstanding questions about how the exogenous application of antioxidants mechanistically affects plant growth.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 2","pages":"407 - 447"},"PeriodicalIF":7.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11101-023-09862-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4002273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications","authors":"Karolina Grabowska,&nbsp;Weronika Buzdygan,&nbsp;Agnieszka Galanty,&nbsp;Dagmara Wróbel-Biedrawa,&nbsp;Danuta Sobolewska,&nbsp;Irma Podolak","doi":"10.1007/s11101-023-09864-1","DOIUrl":"10.1007/s11101-023-09864-1","url":null,"abstract":"<div><p><i>Bassia</i> All. is a genus from the <i>Amaranthaceae</i> family, which was created by merging selected species belonging to the former <i>Bassia</i> and <i>Kochia</i> genera with those classified to <i>Chenolea</i>, <i>Londesia</i>, <i>Kirilowia</i> and <i>Panderia.</i> The reorganised <i>Bassia</i> genus currently comprises around 20 species, which are annual herbs or perennial subshrubs native to Eurasia and Africa. <i>Bassia</i> plants are well known for their therapeutic applications in folk medicine and traditional medical systems, and they are also used for nonmedical purposes. Some members of this genus, such as <i>Bassia scoparia</i> (syn. <i>Kochia scoparia</i>) is of great medical importance and economic value. The plant is cultivated in some regions of Asia as a crop to collect <i>Kochiae fructus,</i> which is used for both curative and food purposes. Phytochemical studies carried out on <i>Bassia</i> species indicate that these plants synthesize metabolites belonging to different groups of compounds (e.g., triterpene saponins, sterols, flavonoids, fatty acids, lignanamides, alkaloids, organic acids). Some of the structures are rarely found in the plant kingdom. Biological activity studies carried out on <i>Bassia</i> plants revealed various effects exerted by extracts and isolated compounds, including anti-inflammatory, cytotoxic, antioxidant, antimicrobial, hypoglycemic, anti-obesity, etc. Modern research explained some of the mechanisms of action. This review covers literature from 1935 to 2022, and assembles and discusses data on phytochemistry, biological activity, as well as medical and nonmedical use of the representatives of the genus <i>Bassia</i>. In this review we present the current state of knowledge about the plants of the genus.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 5","pages":"1197 - 1246"},"PeriodicalIF":7.7,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11101-023-09864-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41084304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential avenue of genetic engineered algal derived bioactive compounds: influencing parameters, challenges and future prospects","authors":"Richa Kothari,&nbsp;Har Mohan Singh,&nbsp;Rifat Azam,&nbsp;Kajol Goria,&nbsp;Anu Bharti,&nbsp;Anita Singh,&nbsp;Somvir Bajar,&nbsp;Ashish Pathak,&nbsp;A. K. Pandey,&nbsp;V. V. Tyagi","doi":"10.1007/s11101-023-09859-y","DOIUrl":"10.1007/s11101-023-09859-y","url":null,"abstract":"<div><p>The rising living standards of humans have a high demand for natural resources. Algal biomass has emerged as a substitute for conventional resources obtained from animals and plants. Compositionally, algae constitute extractable carbohydrates, proteins, lipids, and other valuable bioactive compounds (BACs) in abundance. BACs profusely derived from algal biomass include long-chain polysaccharides, fatty acids such as mono- and polyunsaturated fatty acids (MUFA and PUFA), phenols, and proteins. The coupling of wastewater with algae for resource recovery for the BACs extraction can serve as a source of plenteous biochemicals with high industrial values like pigments, polysaccharides, lipids, antioxidants, and growth-promoting compounds. Extracted algal BACs can incorporate in the manufacturing of numerous cosmetic products, pharmaceuticals, and nutraceuticals. The productivity and quality of algal produce are still low relative to their demand. Genetic engineering has emerged as a proven approach to enhance the quality and quantity of algal produces and provide a better avenue for biofuel and value-added chemicals productions. Currently, genetic engineering has grabbed significant attention from researchers, and continuous efforts are encouraged to improve industrially viable algal species that can satisfy future demand. This article focuses on the wide range of BACs derived from algae and wastewater for resource recovery, genetic engineering in algae for BACs, influencing processing parameters for genetic engineered algae, concerns associated with genetic engineered algae, and future perspective.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"22 4","pages":"935 - 968"},"PeriodicalIF":7.7,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11101-023-09859-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4796255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}