HRB open research最新文献

{"title":"An exploration of the social determinants of the health and well-being among older African immigrants living in San Diego. A socio-ecological approach","authors":"Purity Mwendwa, Tala Al-Rousan","doi":"10.12688/hrbopenres.13820.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13820.1","url":null,"abstract":"Background As immigration continues to be a global phenomenon, the number of aging immigrants will increase. There is a knowledge gap in the United States on the social determinants of health among older immigrants, especially the older refugee population. We aimed to explore the social determinants of health among older African immigrants living in San Diego, California, and to suggest strategies that can inform the design of health-promoting interventions. Methods We employed a qualitative approach using semi-structured interviews with 11 participants (nine females and two males). We used deductive thematic analysis to explore and analyse the factors that influence their health and well-being based on the five levels of the socio-ecological model (individual, interpersonal, organizational, community, and public policy). Results Participants were aged between 62 and 90 years; eight participants had arrived as refugees. Thematic analysis resulted in the following themes within the five levels: individual (pre-migration and migration experiences and impact on health, aging-related health decline, sedentary lifestyle, side effects of medications,language barrier); interpersonal (social support and social participation); organizational (access to healthcare and support services, transportation, - disruption to services due to COVID-19, perception of healthcare and support services); community (social, emotional and practical support, connecting older adults to services) and public policy (financial barriers, immigration policies and legal status). Conclusions Given the distinct linguistic and cultural backgrounds coupled with the unique health needs of our study participants, there is a need for diverse and complementary interventions that seek to build a sense of community and social support for older adults. Such interventions ought to be co-developed with immigrant communities and local organizations to ensure cultural acceptability and effectiveness. Crucially needed are immigration policies that consider the unique situation of older immigrants from low-income backgrounds to ensure equitable access to health and social care services.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"72 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140665584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of a stroke research Public Patient Involvement Panel","authors":"S. O'Reilly, A. Whiston, Eva Corbett, Amy O'Mahony, Molly X Manning, Pauline Boland, Katie Robinson, Rose Galvin, Joanna M Allardyce, Mike Butler, Jim Bradley, Jon Salsberg, Margaret O’Connor, Patricia Pond, Eva Murphy, Liam Glynn, N. Cunningham, Edel Hennessy, S. Hayes","doi":"10.12688/hrbopenres.13838.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13838.1","url":null,"abstract":"Background Public and patient involvement (PPI) is important in stroke research to ensure that research conducted reflects the priorities and needs of people after stroke. Several factors have been found to affect PPI, including location of the research and time requirements for participation. The incidence of stroke is rising, and can result in symptoms including fatigue, depression, and physical/cognitive impairments. Aims 1) Describe the development of a PPI advisory group and a healthcare professional advisory group for stroke rehabilitation research and 2) to explore the perspectives of the members of the PPI groups on being involved in the research process. Methods A stakeholder panel consisting of up to 20 people with stroke, members of the public and healthcare professionals will be formed. A pragmatic purposive sampling technique using snowball sampling will be used to recruit members. The PPI panel will meet four times and will be supported by the guidelines developed from the INVOLVE framework. The PPI panel will be involved as co-researchers in the conceptualisation of future stroke rehabilitation research, the delivery of such studies, the analysis and dissemination of findings. Following the development of the panel, we will conduct semi-structured focus groups to collect qualitative data, examining the perspectives of members. Separate focus groups will be held for people with stroke, family members/cares, and healthcare professionals/researchers. Data will be transcribed and analysed using Braun and Clarke’s Reflexive Thematic Analysis. This will result in a set of themes and subthemes describing participants' opinions and experience of being on a PPI panel in stroke rehabilitation research. Conclusions PPI is an essential part of research in stroke. Stakeholders can provide key insights into the research processes. The results of this qualitative study will provide insight into the barriers and enablers of their participation in PPI in stroke rehabilitation research.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"78 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140665239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of infertility research conducted in the Republic Of Ireland","authors":"Áine Earley, Angela O’Dea, C. Madden, Paul O'Connor, D. Byrne, Andrew W. Murphy, S. Lydon","doi":"10.12688/hrbopenres.13877.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13877.1","url":null,"abstract":"Background Approximately 25 million citizens in Europe experience infertility. Until September 2023, the Republic of Ireland (RoI) was the only state in the European Union that did not offer any state-funded access to Assisted Reproductive Technology (ART). As research supports the understanding, and improvement, of care delivery, and research activity is associated with healthcare performance, it seems timely to develop an understanding of infertility research to-date in RoI. The aim of this scoping review was to examine the extent and nature of research on infertility conducted in RoI. Methods A protocol for this scoping review was published through the Open Science Framework (https://doi.org/10.17605/OSF.IO/H8F4Y) in March 2023. The search strategy was comprised of electronic searches, review of reference lists, grey literature searches, and screening of publications from the European Society of Human Reproduction and Embryology and the International Committee for Monitoring Assisted Reproductive Technologies. Studies focused on infertility or infertility care that were conducted in RoI were included. Deductive content analysis was used to cluster studies. Results In total, 105 studies were included and published between 1951 and 2023, with a marked increase from 2010. Studies most frequently considered Success Rates of ART (31.4%), Service Description and Evaluation (12.4%), and Optimising Treatment Regimes or Protocols (11.4%). Conclusions The sizable body of research is congruent with the increasing burden of infertility. However, the literature is limited by a predominant focus on ART success rates, a dearth of qualitative studies, limited engagement with healthcare providers, and limited exploration of the quality of care provision. This review may offer a useful model for researchers in other countries. The variability in availability, and outcomes, of ART across Europe conveys the necessity of understanding and advancing research within individual countries and health systems as well as internationally.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"117 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140659426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of positive childhood experiences on adult psychiatric disorder and symptoms: Protocol for a systematic review and meta-analysis of longitudinal cohort studies","authors":"L. Telford, C. Healy, Éilis J O’Reilly, Mary C Clarke","doi":"10.12688/hrbopenres.13833.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13833.1","url":null,"abstract":"Background Mental and substance use disorders are the leading cause of disability among young people worldwide. Early life environments and experiences have a significant influence on development with long-lasting implications for both physical and mental health. While the harmful effects of childhood adversity are well-documented, positive childhood experiences are less well-established and the degree of association with later mental health outcomes is currently undefined. The proposed systematic review will therefore examine the literature exploring associations between exposure to positive childhood experiences and the development of psychiatric disorder or symptoms in adulthood. Methods and analysis Studies examining associations between exposure to positive childhood experiences and risk of adult psychiatric disorder or symptoms will be systematically identified by searching Embase, APA PsycInfo, MEDLINE, and Scopus. Customised search strategies will be built for each database by combining key search terms relating to inclusion criteria. No restrictions on publication date will be applied, however searches will be restricted to the English language. Provided data are sufficient, a random-effects model at the 0.05 level of significance will be used to pool quantitative effect estimates. If meta-analysis is not possible, results will be summarised in tables and reported narratively. The Joanna Briggs Institute Critical Appraisal Checklist for Cohort Studies will be used for quality assessment of included studies and the overall strength of the body of evidence will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation framework. Heterogeneity between included studies will be explored through visual inspection of forest plots and by assessing the I2 statistic. Reporting of this protocol has been guided by the standards of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols Statement. Ethics and dissemination Only published data will be used for this review therefore ethical approval is not required. Findings will be disseminated in a scientific peer-reviewed journal and results presented at conferences.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140688809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the feasibility of a comprehensive patient reported outcome set for postpartum women: the maternal patient-reported outcome set (MOMs Study)","authors":"L. O'Byrne, G. Maher, Jill M Mitchell, Ali Khashan, Richard Greene, John Browne, Fergus McCarthy","doi":"10.12688/hrbopenres.13876.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13876.1","url":null,"abstract":"Background Our team published a systematic review highlighting the lack of a comprehensive measure of health and wellbeing for postpartum women. The aim of this project was to examine the feasibility of a combination of existing measures, chosen for their coverage of key domains and psychometric rigour. The primary objective was to examine the validity and completeness of the novel outcome set within the first week (T1), 6 weeks (T2), and 12 weeks postpartum (T3). Secondary objectives were to examine concordance between patient-clinician reports of delivery complications and assess postpartum response rates. Methods Participants completed demographic and delivery details as well as completing a combination of existing PROM tools: the PQoL (Postpartum women’s Quality of life questionnaire), ICIQ-UI-SF (International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form) and 2 sexual health questions. Participants also rated the validity of these tools. Results The response rates were 69% (n=59)T1, 67% (n=57)T2 and 48% (41)T3. Complete responses at T1 55% (n=47),T2 53% (n=45)T3 44% (n=37). The median time taken to complete the survey was 7 minutes. Across the three time points ~70% (70.2% T1, 73.3% T2, 69% T3) of respondents felt that all outcomes that mattered most to them were captured. The difference between complication rates reported by patients and clinicians was 0% for neonatal and high-dependency unit admissions. Obstetric anal sphincter injury (OASI) was reported by 2 patients and 1 clinician. Postpartum haemorrhage (PPH) was reported by 4 (28%) despite electronic records recording PPH occurrence in 14 patients at T1. Conclusions A combination of tools and additional sexual health questions collected from postpartum women using an online survey across three postnatal time points appears feasible and has good validity and completeness. Patient-clinician concordance in the reporting of complication rates was high for all but PPH where patients tended to report lower rates.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140688664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological factors and diabetic foot ulceration: a scoping review of the bi-directional relationship between diabetic foot ulcer healing and mental health factors","authors":"M. Hanlon, Brian McGuire, C. MacGilchrist, Rosie Dunne, Ellen Kirwan, Deirdre Ní Neachtain, K. Dhatariya, V. Blanchette, H. Durand, Anda Dragomir, Caroline McIntosh","doi":"10.12688/hrbopenres.13755.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13755.1","url":null,"abstract":"Introduction Diabetic foot ulceration (DFU) is a major complication of diabetes and is associated with high morbidity and mortality rates. Psychological factors are believed to play a role in wound healing, but it remains uncertain if psychological interventions can help individuals with an active DFU, or a history of DFUs, to achieve complete or improved wound healing or prevent recurrence. Objective The objective of the proposed scoping review is to investigate the emotional consequences/burden of living with DFU and to examine how psychosocial factors may impact progression and management of ulcerations. Methods This review will be conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews and the Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) will guide the reporting of results. Discussion While factors such as stress, depression, social support, and adherence to treatment have been identified as variables that may negatively affect DFU healing, there is a need for a greater understanding of how psychological and behavioural variables such as these may influence ulcer incidence, healing and recurrence in people with diabetes. This review will comprise of a broad and systematically mapped synthesis of the identified data. Findings will be used to provide a better understanding of the bi-directional relationship between DFU and psychological variables and will provide direction for the development or adaptation of a tailored psychological intervention that will aim to optimise wellbeing and improve outcomes for individuals with DFU.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140689218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The economic impact of living with a rare disease for children and their families: a scoping review protocol.","authors":"Niamh Buckle, Orla Doyle, Naonori Kodate, Suja Somanadhan","doi":"10.12688/hrbopenres.13765.2","DOIUrl":"10.12688/hrbopenres.13765.2","url":null,"abstract":"<p><strong>Background: </strong>Rare diseases are an often chronic, progressive and life-limiting group of conditions affecting more than 30 million people in Europe. These diseases are associated with significant direct and indirect costs to a spectrum of stakeholders, ranging from individuals and their families to society overall. Further quantitative research on the economic cost for children and their families living with a rare disease is required as there is little known on this topic. This scoping review aims to document the extent and type of evidence on the economic impacts of living with a rare disease for children and their families.</p><p><strong>Methods: </strong>This scoping review will follow the PRISMA-ScR and Joanna Briggs Institute guidelines and follow the six-stage methodology for scoping reviews: (1) identifying the research question, (2) identifying relevant studies, (3) study selection, (4) charting the data, (5) collating, summarising and reporting results and (6) knowledge user consultation. Key inclusion criteria have been developed according to the Population-Concept-Context (PCC) framework. The databases EconLit, ABI/Inform, MEDLINE, PubMed, CINAHL, and Scopus will be searched for possible articles for inclusion. Two independent reviewers will screen titles and abstracts of potential articles using a dual review process to ensure all relevant studies are included. All included articles will be assessed using a validated quality appraisal tool. A panel of patient and public involvement representatives experiencing rare diseases and knowledge users will validate the review results.</p><p><strong>Conclusions: </strong>This scoping review will map the current literature on the economic impact of paediatric rare diseases to understand how these impacts affect children living with rare diseases and their families. This evidence has the potential to influence policy and future research in this area and will support further research on the economic impact of rare diseases on families.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11187531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Participation in physical activity by adolescents with physical disability: Protocol for a national participation snapshot and Delphi consensus study (“Youth Experience Matters”)","authors":"K. Brady, D. Kiernan, Elaine McConkey, Eva O'Gorman, Claire Kerr, Suzanne M. McDonough, Jennifer Ryan, A. Malone","doi":"10.12688/hrbopenres.13741.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13741.2","url":null,"abstract":"Young people with physical disability experience challenges to being physically active. To attain the health benefits of physical activity (PA) and sustain engagement, it is essential that participation is meaningful and enjoyable. This study aims to describe current participation in PA by adolescents with physical disability in Ireland, and to establish consensus on their priorities for enhancing physical activity participation. A parallel convergent mixed methods study will be undertaken, comprising a national cross-sectional quantitative assessment of PA participation (“Participation Snapshot”) and Delphi consensus study (“Delphi”). Adolescents (n=100) aged 13–17 years with a physical disability will be invited to take part. The Participation Snapshot primary outcome is the Children’s Assessment of Participation and Enjoyment (CAPE). Contextual factors including underlying medical diagnosis, demographics, mobility (Functional Mobility Scale), hand function (Manual Ability Classification System) and health related quality of life (Child Health Utility 9D) will also be collected. The Delphi will comprise two to four survey rounds, until consensus is reached. Round 1 consists of a bespoke survey, designed and piloted with a public and patient involvement (PPI) panel, with open-ended questions and Likert scales inviting contributions from adolescents on their prior experience and ideas to enhance participation. Responses will be analysed using inductive thematic analysis to construct items and themes, which will then be deductively mapped to the “F-words” and the family of Participation-Related Constructs frameworks. These items will be presented back to participants in subsequent rounds for selection and ranking, until consensus is achieved on the “top 10 priorities” for enhancing PA participation. The project team and PPI panel will then co-design dissemination material and identify targets for dissemination to relevant stakeholder or policy groups. The findings will provide a basis for developing interventions aiming to enhance future PA participation for adolescents with physical disability.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140743818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare workers' perspectives on barriers and facilitators to referral and recruitment to diabetes prevention programmes: a systematic review protocol.","authors":"Clair Haseldine, Gráinne O'Donoghue, Patricia M Kearney, Fiona Riordan, Sarah Cotterill, Sheena McHugh","doi":"10.12688/hrbopenres.13702.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13702.2","url":null,"abstract":"<p><strong>Background: </strong>Diabetes is a growing global health problem. International guidelines recommend identification, screening, and referral to behavioural programmes for those at high risk of developing type 2 diabetes. Diabetes prevention programmes (DPPs) can prevent type 2 diabetes in those at high risk, however many eligible participants are not referred to these programmes. Healthcare workers (HCWs) are pivotal to the referral and recruitment processes. This study aims to identify, appraise and synthesise the evidence on barriers and facilitators to referral and recruitment to DPPs from the perspective of HCWs.</p><p><strong>Methods: </strong>A \"best fit\" framework synthesis method will synthesise qualitative, quantitative, and mixed methods evidence on factors that affect HCWs referral and recruitment to DPPs, with the Theoretical Domains Framework (TDF) as the <i>a priori</i> framework. MEDLINE, EMBASE, CINAHL, PsychINFO, Web of Science and Scopus will be searched for primary studies published in English. Year of publication will be restricted to the last 26 years (1997-2023). Quality will be assessed using the Mixed Methods Appraisal Tool. A mix of deductive coding using the TDF and inductive coding of data that does not fit the TDF will be synthesised into themes representing the whole dataset. The relationships between the final set of themes will be explored to create a new model to understand HCWs' perspectives on referral and recruitment to DPPs. Sensitivity analysis will be carried out on this conceptual model. Confidence in the synthesised findings will be assessed using the GRADE-CERQual approach. One author will screen, extract, appraise the literature while a second author will independently verify a 20% sample at each stage.</p><p><strong>Discussion: </strong>Participation in DPPs is key for programme impact. HCWs typically identify those at risk and refer them to DPPs. Understanding HCWs' perspectives on the barriers and facilitators to referral and recruitment will inform future implementation of DPPs.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11004599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between intrapartum fetal pulse oximetry and adverse perinatal and long-term outcomes: a systematic review and meta-analysis protocol.","authors":"Jill M Mitchell, Siobhan Walsh, Laura J O'Byrne, Virginia Conrick, Ray Burke, Ali S Khashan, John Higgins, Richard Greene, Gillian M Maher, Fergus P McCarthy","doi":"10.12688/hrbopenres.13802.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13802.2","url":null,"abstract":"<p><strong>Background: </strong>Current methods of intrapartum fetal monitoring based on heart rate, increase the rates of operative delivery but do not prevent or accurately detect fetal hypoxic brain injury. There is a need for more accurate methods of intrapartum fetal surveillance that will decrease the incidence of adverse perinatal and long-term neurodevelopmental outcomes while maintaining the lowest possible rate of obstetric intervention. Fetal pulse oximetry (FPO) is a technology that may contribute to improved intrapartum fetal wellbeing evaluation by providing a non-invasive measurement of fetal oxygenation status.</p><p><strong>Objective: </strong>This systematic review and meta-analysis aims to synthesise the evidence examining the association between intrapartum fetal oxygen saturation levels and adverse perinatal and long-term outcomes in the offspring.</p><p><strong>Methods: </strong>We will include randomised control trials (RCTs), cohort, cross-sectional and case-control studies which examine the use of FPO during labour as a means of measuring intrapartum fetal oxygen saturation and assess its effectiveness at detecting adverse perinatal and long-term outcomes compared to existing intrapartum surveillance methods. A detailed systematic search of PubMed, EMBASE, CINAHL, The Cochrane Library, Web of Science, ClinicalTrials.Gov and WHO ICTRP will be conducted following a detailed search strategy until February 2024. Three authors will independently review titles, abstracts and full text of articles. Two reviewers will independently extract data using a pre-defined data extraction form and assess the quality of included studies using the Risk of Bias tool for RCTs and Newcastle-Ottawa Scale for observational studies. The grading of recommendations, assessment, development, and evaluation (GRADE) approach will be used to evaluate the certainty of the evidence. We will use random-effects meta-analysis for each exposure-outcome association to calculate pooled estimates using the generic variance method. This systematic review will follow the Preferred Reporting Items for Systematic reviews and Meta-analyses and MOOSE guidelines.</p><p><strong>Prospero registration: </strong>CRD42023457368 (04/09/2023).</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11019289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}