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A study to explore the role of a low threshold, fitness focussed physical rehabilitation intervention with protein supplementation to target physical function and frailty in people with problematic substance use and homelessness: protocol for a single-arm pre-post intervention study. 一项探索低门槛、以健身为重点的身体康复干预与蛋白质补充的作用的研究,以有问题药物使用和无家可归者的身体功能和虚弱为目标:单臂事后干预研究方案。
HRB open research Pub Date : 2024-10-29 eCollection Date: 2023-01-01 DOI: 10.12688/hrbopenres.13678.2
Fiona Kennedy, Clíona Ní Cheallaigh, Roman Romero-Ortuno, Suzanne Doyle, Julie Broderick
{"title":"A study to explore the role of a low threshold, fitness focussed physical rehabilitation intervention with protein supplementation to target physical function and frailty in people with problematic substance use and homelessness: protocol for a single-arm pre-post intervention study.","authors":"Fiona Kennedy, Clíona Ní Cheallaigh, Roman Romero-Ortuno, Suzanne Doyle, Julie Broderick","doi":"10.12688/hrbopenres.13678.2","DOIUrl":"10.12688/hrbopenres.13678.2","url":null,"abstract":"<p><strong>Background: </strong>People who are homeless are more likely to experience poor mental health and addiction as well as suffering from non-communicable diseases. There is evidence of frailty and accelerated physical ageing among people experiencing homelessness. Appropriate physical rehabilitation and nutritional supplementation strategies can stabilise or reverse frailty and general physical decline, but it is not known how this type of intervention would work in practice in this population.</p><p><strong>Aim: </strong>To evaluate the feasibility and pre-post intervention impact of a low threshold physical rehabilitation intervention with protein supplementation to target physical functioning and frailty in people with problematic substance use who are experiencing homelessness.</p><p><strong>Methods: </strong>The intervention will consist of a 12-week low threshold rehabilitation programme with protein supplementation. Participants will be service users of the Ballyfermot Advance Project, a day services centre for people with addiction issues and experiencing homelessness. Primary outcomes will be feasibility including numbers recruited, retention of participants and adherence to the exercise intervention and protein supplement. Any adverse events will be recorded. Secondary outcomes will be strength and muscular mass, physical performance and lower extremity physical function, pain, frailty and nutritional status.</p><p><strong>Discussion: </strong>An immediate impact may be simply a distraction from difficult circumstances and potentially an improvement of physical health of participants, which can be a conduit for the emergence of other positive behaviours and recovery. Longer term, this study will generate preliminary data on which to inform the design of a definitive randomised controlled trial of physical rehabilitation and protein supplementation, if indicated.</p><p><strong>Ethics and dissemination: </strong>Ethical approval was granted by the Faculty of Health Sciences Research Ethics Committee in TCD. Study findings will be disseminated through publication into an international peer-reviewed journal and presented at national and international conferences.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"26"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocol for a systematic search and critical discourse analysis of research on national HIV pre-exposure prophylaxis programmes among gay, bisexual, and other men who have sex with men. 对男同性恋、双性恋和其他男男性行为者中的国家 HIV 暴露前预防计划研究进行系统搜索和批判性话语分析的规程。
HRB open research Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.12688/hrbopenres.13841.2
David Comer, Chris Noone
{"title":"Protocol for a systematic search and critical discourse analysis of research on national HIV pre-exposure prophylaxis programmes among gay, bisexual, and other men who have sex with men.","authors":"David Comer, Chris Noone","doi":"10.12688/hrbopenres.13841.2","DOIUrl":"10.12688/hrbopenres.13841.2","url":null,"abstract":"<p><strong>Background: </strong>HIV pre-exposure prophylaxis (PrEP) is a medication that prevents the acquisition of HIV, most commonly taken in the form of a pill. PrEP is an efficacious tool for HIV prevention, including among gay, bisexual, and other men who have sex with men (gbMSM). PrEP is often provided through formal PrEP programmes. Research on these programmes may employ discourses shaped by heteronormativity and homophobia. Given that expert language influences how HIV prevention is understood and delivered, problematic discourses in research likely extend into PrEP implementation. This study will use critical discourse analysis (CDA) to explore research on PrEP programme implementation for gbMSM. Within this literature, we will identify interpretive repertoires used to discuss gbMSM; the subject positions afforded to gbMSM; and the implications of these interpretive repertoires and subject positions for gbMSM engaging with HIV PrEP programmes.</p><p><strong>Methods: </strong>Systematic search methods identified relevant articles through timebound searching (2012-2023) in ProQuest ASSIA, EBSCOhost PsycInfo, OVID Medline, OVID Embase, and EBSCOhost CINAHL, with forward and backward citation searching of included studies. Grey literature will be identified through ProQuest and Google Scholar. Screening will be conducted by two independent reviewers, who will conduct random partial double screening for titles and abstracts and for all full text articles. Data will be analysed and synthesised using CDA informed by critical realism (CR). CDA focuses on relationships between language and power, including how language enables inequality. The analytic process will explore the background of included studies, identify themes, and analyse external and internal relations in included studies.</p><p><strong>Conclusions: </strong>Highlighting issues with discourses in PrEP implementation may enhance reflective engagement with assumptions underlying this research, preventing further stigmatisation of gbMSM's sexual and protective practices. As PrEP programmes become more common, diverse and inclusive perspectives in PrEP programme research may inform interventions that enhance their acceptability and implementation.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"7 ","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Altmetric coverage of health research in Ireland 2017-2023: a protocol for a cross-sectional analysis. 2017-2023年爱尔兰健康研究的Altmetric覆盖率:横向分析协议。
HRB open research Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.12688/hrbopenres.13895.2
Melissa K Sharp, Patricia Logullo, Pádraig Murphy, Prativa Baral, Sara Burke, David Robert Grimes, Máirín Ryan, Barbara Clyne
{"title":"Altmetric coverage of health research in Ireland 2017-2023: a protocol for a cross-sectional analysis.","authors":"Melissa K Sharp, Patricia Logullo, Pádraig Murphy, Prativa Baral, Sara Burke, David Robert Grimes, Máirín Ryan, Barbara Clyne","doi":"10.12688/hrbopenres.13895.2","DOIUrl":"10.12688/hrbopenres.13895.2","url":null,"abstract":"<p><strong>Background: </strong>Scientific publications have been growing exponentially, contributing to an oversaturated information environment. Quantifying a research output's impact and reach cannot be solely measured by traditional metrics like citation counts as these have a lag time and are largely focused on an academic audience. There is increasing recognition to consider 'alternative metrics' or altmetrics to measure more immediate and broader impacts of research. Better understanding of altmetrics can help researchers better navigate evolving information environments and changing appetites for different types of research.</p><p><strong>Objectives: </strong>Our study aims to: 1) analyse the amount and medium of Altmetric coverage of health research produced by Irish organisations (2017 - 2023), identifying changes over time and 2) investigate differences in the amount of coverage between clinical areas (e.g., nutrition vs. neurology).</p><p><strong>Methods: </strong>Using Altmetric institutional access, we will gather data on research outputs published 1 January 2017 through 31 December 2023 from active Irish organisations with Research Organisation Registry (ROR) IDs. Outputs will be deduplicated and stratified by their Australian and New Zealand Standard Research Classification relating to ≥1 field of health research: Biological Sciences, Biomedical and Clinical Sciences, Chemical Sciences, Health Sciences, and Psychology. We will clean data using R and perform descriptive analyses, establishing counts and frequencies of coverage by clinical area and medium (e.g., traditional news, X, etc.); data will be plotted on a yearly and quarterly basis where appropriate.</p><p><strong>Results and conclusions: </strong>Improved understanding of one's information environment can help researchers better navigate their local landscapes and identify pathways for more effective communication to the public. All R code will be made available open-source, allowing researchers to adapt it to evaluate their local landscapes.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"7 ","pages":"36"},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Initial Implementation of a Clinical Monitoring Strategy in a Non-regulated Trial: a research note from the ReStOre II Trial. 非规范试验中临床监控策略的制定和初步实施:ReStOre II 试验的研究说明。
HRB open research Pub Date : 2024-10-18 eCollection Date: 2023-01-01 DOI: 10.12688/hrbopenres.13763.2
Linda O'Neill, Fiona Murphy, Derval Reidy, Camille Poisson, Juliette Hussey, Emer Guinan
{"title":"Development and Initial Implementation of a Clinical Monitoring Strategy in a Non-regulated Trial: a research note from the ReStOre II Trial.","authors":"Linda O'Neill, Fiona Murphy, Derval Reidy, Camille Poisson, Juliette Hussey, Emer Guinan","doi":"10.12688/hrbopenres.13763.2","DOIUrl":"10.12688/hrbopenres.13763.2","url":null,"abstract":"<p><strong>Background: </strong>Data and Safety Monitoring is integral to quality assurance of clinical trials. Although monitoring is a core legal component of regulated clinical trials, non-regulated trials are not mandated to incorporate monitoring. Consequently, the monitoring process has been underutilised and underreported in this setting. This research report outlines the development and plans for implementing a bespoke Clinical Monitoring Strategy within the ' <i>Rehabilitation Strategies Following Oesophagogastric and Hepatopancreaticobiliary Cancer (ReStOre II) Trial'</i>, a non-regulated trial comparing a 12-week multidisciplinary programme of rehabilitation to standard care in a cohort of 120 cancer survivors.</p><p><strong>Methods: </strong>This research note provides a detailed overview of the ReStOre II Clinical Monitoring Strategy and describes the development of the strategy pre and post awarding of the grant. The strategy consists of the establishment and implementation of a comprehensive trial governance structure, inclusive of a Trial Management Group, Trial Steering Committee Meeting, and Independent Data Monitoring Committee. In addition, external trial monitoring by the Clinical Research Facility at St James's Hospital. Three monitoring visits will be conducted during the trial; i) site initiation visit, ii) interim monitoring visit, and iii) close our visit.</p><p><strong>Results: </strong>The Clinical Monitoring Strategy has been finalised and is currently being implemented within the ReStOre II Trial. Two site initiation visits and one interim monitoring visit have been completed to date.</p><p><strong>Conclusion: </strong>This research note provides a template for implementation of a Clinical Monitoring Strategy in a non-regulated clinical trial.</p><p><strong>Registration: </strong>ReStOre II Trial: https://clinicaltrials.gov/ct2/show/NCT03958019.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"46"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11401978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The emerging role of a Stroke Clinical Nurse Specialist (CNS) in Early Supported Discharged: Developing a pathway for stroke nursing for secondary prevention in the community.  A scoping review protocol. 卒中临床护理专家(CNS)在早期支持出院中的新兴角色:开发社区二级预防卒中护理路径。 范围审查协议。
HRB open research Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.12688/hrbopenres.13818.2
Sarah-Jane Byrne, David J Williams, Declan Patton, Paul J Murphy, Frances Horgan
{"title":"The emerging role of a Stroke Clinical Nurse Specialist (CNS) in Early Supported Discharged: Developing a pathway for stroke nursing for secondary prevention in the community.  A scoping review protocol.","authors":"Sarah-Jane Byrne, David J Williams, Declan Patton, Paul J Murphy, Frances Horgan","doi":"10.12688/hrbopenres.13818.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13818.2","url":null,"abstract":"<p><strong>Background: </strong>Stroke represents a major source of mortality and morbidity globally. The role of a stroke Clinical Nurse Specialist (CNS) as an expert team member in early supported discharge (ESD) for stroke, is not well defined or described although it is well established in other models of after-hospital and out-reach specialist care in the community. A greater focus has been on patients receiving rehabilitation post-stroke, however there is a need for a more holistic approach to care which clinical nurse specialists can offer to patients as part of ESD. Nurses are often the cohesive point of contact for other after-hospital services, managing many aspects of secondary prevention.</p><p><strong>Objective: </strong>The aim of this scoping review is to explore the evidence in relation to the role of the stroke nurse providing secondary prevention interventions to stroke patients in a community setting.</p><p><strong>Methods: </strong>We will conduct a scoping review in accordance with the Arksey and O'Malley, 2005 <sup>1</sup> scoping review framework and the PRISMA-ScR guidelines to map available literature on the role of the stroke nurse in post-stroke care of patients in the community. The Cochrane Central Register of Controlled Trials and Systematic literature searches including databases MEDLINE, EMBASE, CINAHL, google scholar and grey literature will be searched using keyword searches. Data will be charted and synthesised and a narrative synthesis will be conducted.</p><p><strong>Conclusions: </strong>This scoping review will be used to identify gaps in the current literature and identify areas for future research in the role of the stroke nurse in ESD in relation to secondary prevention for stroke patients and inform the development of a pathway for stroke nursing in ESD.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"7 ","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracking aspects of healthcare activity during the first nine months of COVID-19 in Ireland: a secondary analysis of publicly available data. 追踪爱尔兰 COVID-19 前九个月医疗保健活动的各个方面:对公开数据的二次分析。
HRB open research Pub Date : 2024-09-13 eCollection Date: 2021-01-01 DOI: 10.12688/hrbopenres.13372.3
Domhnall McGlacken-Byrne, Sarah Parker, Sara Burke
{"title":"Tracking aspects of healthcare activity during the first nine months of COVID-19 in Ireland: a secondary analysis of publicly available data.","authors":"Domhnall McGlacken-Byrne, Sarah Parker, Sara Burke","doi":"10.12688/hrbopenres.13372.3","DOIUrl":"https://doi.org/10.12688/hrbopenres.13372.3","url":null,"abstract":"<p><strong>Background: </strong>Sláintecare aims to introduce universal healthcare in Ireland. The COVID-19 pandemic poses both challenges and opportunities to this process. This study explored the impact of COVID-19 on aspects of Irish healthcare during the first nine months of the pandemic and considers the implications for Sláintecare implementation.</p><p><strong>Methods: </strong>Secondary analysis was undertaken on publicly available data on three key domains of the Irish healthcare system: primary care, community-based allied healthcare, and hospitals. Descriptive statistics were computed using Microsoft Excel 2016.</p><p><strong>Results: </strong>Up to March 2021, 3.76 million COVID-19 tests were performed by Ireland's public healthcare system, 2.48 million (66.0%) of which were referred from the community. General practitioners delivered 2.31 million telephone triages of COVID-19 symptoms, peaking in December 2020 when 416,607 consultations occurred. Patient numbers across eight allied healthcare specialties fell by 35.1% versus previous years, with the greatest reductions seen in speech and language therapy (49.0%) and audiology (46.1%). Hospital waiting lists increased from 729,937 to 869,676 (or by 19.1%) from January 2019 to January 2021. In January 2021, 629,919 patients awaited a first outpatient clinic appointment, with 170,983 (27.1%) waiting longer than 18 months. The largest outpatient lists were observed in orthopaedic surgery (n=77,257); ear, nose and throat surgery (n=68,073); and ophthalmology (n=47,075). The proportion of patients waiting more than 12 months for a day-case gastrointestinal endoscopy rose from 6.0% in January 2020 to 19.0% in January 2021.</p><p><strong>Conclusions: </strong>Healthcare activity has been significantly disrupted by COVID-19, leading to increased wait times and greater barriers to healthcare access during the pandemic. Yet, Ireland's health system responses also revealed strong willingness and ability to adapt and to implement novel solutions for healthcare delivery, rapidly and at scale. This has demonstrated what is achievable under Sláintecare and provides a unique opportunity to 'build back better' towards sustainable recovery.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"4 ","pages":"98"},"PeriodicalIF":0.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic test accuracy of screening tools for the detection of neurocognitive disorders in older adults post-trauma: A protocol for a systematic review. 用于检测创伤后老年人神经认知障碍的筛查工具的诊断测试准确性:系统综述方案。
HRB open research Pub Date : 2024-09-03 eCollection Date: 2024-01-01 DOI: 10.12688/hrbopenres.13894.2
Niamh A Merriman, Mary E Walsh, Niamh O'Regan, Marie Carrigan, Pamela Hickey, Louise Brent, Catherine Blake
{"title":"Diagnostic test accuracy of screening tools for the detection of neurocognitive disorders in older adults post-trauma: A protocol for a systematic review.","authors":"Niamh A Merriman, Mary E Walsh, Niamh O'Regan, Marie Carrigan, Pamela Hickey, Louise Brent, Catherine Blake","doi":"10.12688/hrbopenres.13894.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13894.2","url":null,"abstract":"<p><strong>Background: </strong>Neurocognitive disorders (NCDs), including delirium, cognitive impairment, or dementia are prevalent in up to 39% of older adults in acute care, particularly older trauma patients. Undiagnosed NCDs result in poor outcomes, such as increased incidence of depressive symptoms, longer length of stay, and mortality.</p><p><strong>Objective: </strong>This study aims to identify the diagnostic test accuracy of screening tools for the detection of NCDs in older trauma patients in acute settings.</p><p><strong>Design: </strong>Systematic review protocol.</p><p><strong>Literature search: </strong>Electronic databases (MEDLINE, Embase, CINAHL, PsycInfo, Cochrane Library) will be searched for journal articles. Search terms related to NCDs, delirium and cognitive screening tools, and diagnostic accuracy will be included.</p><p><strong>Study selection criteria: </strong>Cross-sectional, prospective, or retrospective cohort studies of adults aged ≥60 post-trauma, in an acute setting, will be included where the study aimed to validate a screening tool for detection of 1) delirium or 2) cognitive impairment, or dementia against a reference standard of a clinical decision, based on standardised diagnostic criteria or a validated tool.</p><p><strong>Data synthesis: </strong>Two review authors will conduct study selection, data extraction, and appraisal. Data will be extracted based on the Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies (PRISMA-DTA) checklist. Studies will be assessed for methodological quality by two independent review authors using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. Narrative summaries will be generated describing risk of bias and concerns regarding applicability. Quantitative synthesis of study findings will be conducted.</p><p><strong>Conclusion: </strong>This systematic review will aim to identify screening tools with the best diagnostic accuracy for detection of 1) delirium and 2) cognitive impairment or dementia in adults aged ≥60 post-trauma in acute care settings. Results will inform clinical practice to enhance the probability of patients with NCDs receiving appropriate care and management.</p><p><strong>Registration: </strong>PROSPERO https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024518730 (11/03/2024).</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"7 ","pages":"33"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11437317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and incidence of peripheral neuropathy, peripheral artery disease, foot disease, and lower extremity amputation in people with diabetes in Ireland; a systematic review protocol. 爱尔兰糖尿病患者周围神经病变、周围动脉疾病、足部疾病和下肢截肢的患病率和发病率;系统性审查协议。
HRB open research Pub Date : 2024-08-21 eCollection Date: 2024-01-01 DOI: 10.12688/hrbopenres.13823.2
Sinead Kavanagh, Jennifer A Pallin, Ann Sinead Doherty, Peter Lazzarini, Linda O'Keeffe, Claire M Buckley
{"title":"Prevalence and incidence of peripheral neuropathy, peripheral artery disease, foot disease, and lower extremity amputation in people with diabetes in Ireland; a systematic review protocol.","authors":"Sinead Kavanagh, Jennifer A Pallin, Ann Sinead Doherty, Peter Lazzarini, Linda O'Keeffe, Claire M Buckley","doi":"10.12688/hrbopenres.13823.2","DOIUrl":"10.12688/hrbopenres.13823.2","url":null,"abstract":"<p><strong>Introduction: </strong>Internationally, the prevalence of diabetes is increasing, and with this comes an increase in diabetes related complications. Diabetic foot disease is the most common lower extremity complication in people with diabetes causing 2% of the global disease burden. It, is associated with major morbidity, mortality, and costs to health services. Despite this burden, the incidence and prevalence of diabetic foot disease is unknown in Ireland. This paper presents a protocol for a systematic review to examine the incidence and prevalence of diabetic foot disease in the Irish population.</p><p><strong>Methods: </strong>A systematic review will be performed using the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Pubmed, EMBASE, and Lenus, the Irish Health Research repository, will be searched for publications in any language and without restrictions to date. Title, abstract, and full text screening will be carried out independently by two investigators. Publications reporting on the incidence or prevalence of peripheral neuropathy, peripheral artery disease, ulceration, or amputation in people with diabetes in Ireland, from a defined geographical catchment area of Ireland, will be included. Joanna Briggs Institute (JBI) Critical Appraisal tool will be used to assess included studies methodological quality. Results will be reported in line with the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines.</p><p><strong>Conclusion: </strong>The results of this systematic review can be used to inform appropriate stakeholders on the incidence and prevalence of diabetic foot disease in Irish populations, enabling decision making around appropriate use of resources to help prevent, and improve management of this disease.</p><p><strong>Systematic review registration: </strong>CRD42023472904.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"7 ","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contextual factors and intentional rounding in acute hospitals: understanding what works, for whom, in what settings: a realist synthesis protocol. 急症医院中的环境因素和有意查房:了解在什么情况下对什么人有效:现实主义综合方案。
HRB open research Pub Date : 2024-08-21 eCollection Date: 2023-01-01 DOI: 10.12688/hrbopenres.13792.2
Aileen Hetherton, Frances Horgan, Jan Sorensen, Siobhan E Mc Carthy
{"title":"Contextual factors and intentional rounding in acute hospitals: understanding what works, for whom, in what settings: a realist synthesis protocol.","authors":"Aileen Hetherton, Frances Horgan, Jan Sorensen, Siobhan E Mc Carthy","doi":"10.12688/hrbopenres.13792.2","DOIUrl":"10.12688/hrbopenres.13792.2","url":null,"abstract":"<p><strong>Background: </strong>This study aims to understand and explain the influence of contextual factors on the implementation of Intentional Rounding in acute hospitals using the realist synthesis methodology.Falls of hospital admitted patients are one of the most frequent concerns for patient safety in the acute hospital environment. The reasons why people fall are complex. International guidelines recommend a multifactorial assessment and effective prevention and management of identified risk factors in order to reduce the number of falls. Intentional Rounding (IR) is one approach for delivering this. IR is an umbrella term, understood as a structured process whereby nurses or care staff carry out regular checks with individual patients using a standardised protocol to address such issues as positioning, pain, personal needs and placement of possessions.</p><p><strong>Methods: </strong>This study will use realist synthesis to understand what works, for whom, in what circumstances, and in what settings. Realist synthesis is a theory driven interpretive approach to evidence synthesis. It is our intention to analyse IR as an intervention, which aims to enhance patient care and safety in hospital settings. The synthesis forms part of a larger implementation study examining interventions that reduce the number of falls that occur in hospitals. Search terms will include intentional rounding, purposeful rounding, comfort rounding and hourly rounding and will encompass search terms beyond IR and falls rates to avoid limiting the synthesis. This synthesis will conform to the RAMESES (realist and meta-narrative evidence synthesis group) publication and reporting quality standards.</p><p><strong>Conclusions: </strong>The findings will inform the next phase of an implementation study on IR in acute hospital settings, to address evidence informed enablers and barriers to IR. The results will be disseminated in a peer-reviewed journal and through presentations.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"72"},"PeriodicalIF":0.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11234086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is known from the existing literature about the treatment of Mallet Injury using 3D printed splints? A Scoping Review Protocol. 关于使用 3D 打印夹板治疗槌状损伤的现有文献有哪些?范围审查协议》。
HRB open research Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.12688/hrbopenres.13865.2
Una M Cronin, Alice Shannon, Micheal Ó hAodha, Aidan O'Sullivan, Niamh M Cummins, Leonard OSullivan
{"title":"What is known from the existing literature about the treatment of Mallet Injury using 3D printed splints? A Scoping Review Protocol.","authors":"Una M Cronin, Alice Shannon, Micheal Ó hAodha, Aidan O'Sullivan, Niamh M Cummins, Leonard OSullivan","doi":"10.12688/hrbopenres.13865.2","DOIUrl":"10.12688/hrbopenres.13865.2","url":null,"abstract":"<p><strong>Background: </strong>Mallet finger injuries are a frequent cause of hospital attendance, being the fifth most common injury in the body. They are therefore a frequent cause of hospital visits. To date, these injuries have primarily been managed using generic splints. As a generic splint provides a generic fit, patients who receive these are not provided with a custom splint experience. As the size and fit of these splints are not bespoke to the patient's anatomy, patients may not always find the fit comfortable and may find complying with these splints difficult at times. However, an opportunity is developing within healthcare where custom splinting can be obtained for some using Three-D (3D) printing. The rationale for this review is to gain an understanding of the research that has been conducted on 3D printing of mallet injury splints.</p><p><strong>Objective: </strong>The objective of this scoping review is to map the current literature on 3D printing associated with mallet finger injury.</p><p><strong>Methods: </strong>The Joanna Briggs Institute (JBI) methodology for scoping reviews will be used throughout along with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Two researchers will search the databases that will include CINAHL, Embase, Cochrane, EbscoHost, Medline/Pubmed, Science Direct, Web of Science, and Google Scholar. The search will include a hand search of sources falling outside the chosen databases. Screen titles, abstracts, and full-text articles will be reviewed by two researchers independently using Rayaan software. The data extracted from the literature will first be presented in a tabulated chart followed by a narrative synthesis.</p><p><strong>Registration: </strong>The protocol was registered on 6 <sup>th</sup> September 2023, with the Open Science Framework. Registration DOI: https://doi.org/10.17605/OSF.IO/FSJPK.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"7 ","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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