HRB open research最新文献

{"title":"Characteristics of participants in the first fully online National Diabetes Prevention Programme: A quantitative survey","authors":"Clair Haseldine, Gráinne O'Donoghue, Patricia M Kearney, Fiona Riordan, Margaret Humphreys, Liz Kirby, Sheena McHugh","doi":"10.12688/hrbopenres.13807.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13807.1","url":null,"abstract":"<ns3:p>Background Diabetes prevention programmes (DPPs) are being implemented around the world to tackle the rise in type 2 diabetes. In 2021/22, the Health Service Executive(HSE) in Ireland piloted a fully online national diabetes prevention programme(NDPP). Characteristics and factors affecting participation may be different among people attending online DPPs compared to face-to-face programmes. The aim of this study was to describe the demographic, psychosocial and health characteristics of participants in the pilot of the online NDPP in Ireland. Methods A survey from the evaluation of the English NDPP was adapted for the Irish context with Patient and Public Involvement(PPI) input. The survey was sent (between April and June 2022) to all individuals who attended the initial assessment of the pilot NDPP (n=73). It contained questions on health status, co-morbidities, motivation to improve health, quality of life, self-efficacy, beliefs about the risk of diabetes, participation(e.g. recollection and understanding of invite, number of sessions attended), as well as demographic information. Results Response rate was 30.5% (n=22). Mean age of responders was 62 years (range 36–82 years) and over half were men (57.1%, n=12). The majority (81%, n=17) had attended 6 or more of the 14 sessions. Most (90.5% n=19) reported having family members or acquaintances with diabetes, had positive views of their current health status and high quality of life scores (71.4%, n= 15). Mental health scores were slightly higher than the national average. Over half (57.2%, n=12) were confident or very confident about participating in an online DPP. Almost all (95.2%, n=20) believed it was important to manage their risk of type 2 diabetes. Conclusions Participants in the online pilot NDPP had positive views of their general health and positive psychosocial characteristics affecting their decision to participate. These beliefs may be modifiable intervention targets to encourage participation among non-attenders in future programmes.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135883073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting men's awareness, self-examination, and help-seeking for testicular disorders: a systematic review of interventions.","authors":"Mohamad M Saab,&nbsp;Martin Davoren,&nbsp;Aileen Murphy,&nbsp;David Murphy,&nbsp;Eoghan Cooke,&nbsp;Margaret Landers,&nbsp;Serena Fitzgerald,&nbsp;Noel Richardson,&nbsp;Michael Rovito,&nbsp;Christian Von Wagner,&nbsp;Mike Murphy,&nbsp;Darren Dahly,&nbsp;Josephine Hegarty","doi":"10.12688/hrbopenres.12837.3","DOIUrl":"10.12688/hrbopenres.12837.3","url":null,"abstract":"<p><p><b>Background:</b> Testicular cancer (TC) is among the most commonly diagnosed cancers in men aged 15-40 years. The incidence of TC is on the rise. Benign testicular disorders, such as testicular torsion and epididymitis, can lead to testicular ischemia, sepsis, and infertility if left untreated. This updated systematic review aims to evaluate the effectiveness of studies promoting men's knowledge and awareness of testicular disorders and/or self-examination, behaviours and/or intentions to examine their testes, and help-seeking behaviours and/or intentions for testicular disorder symptoms. <b>Methods:</b> Academic Search Complete, Medline, CINAHL, PsycINFO, ERIC, the Cochrane Library, the World Health Organisation International Clinical Trials Registry Platform, and Clinicaltrials.gov were searched for studies published between April 2018 and August 2023. Methodological quality was assessed and results were synthesised meta-narratively. <b>Results:</b> Five studies were included. The majority of the reviewed interventions were successful in increasing men's awareness of TC and self-examination, including a PowerPoint presentation, an online educational brochure, video-assisted teaching, a motivational video, and a virtual reality game. Only one study addressed help-seeking for testicular symptoms and promoted men's awareness of benign as well as malignant testicular diseases. <b>Conclusions:</b> This review highlights the importance of evaluating innovative educational interventions aimed at younger men, whilst raising their awareness of testicular disorders and increasing their help-seeking intentions for testicular disorder symptoms. Given the lack of consensus around scheduled testicular self-examination among younger men, clinicians are encouraged to instruct men to familiarise themselves with the look and feel of their own testes and to seek timely medical attention for abnormalities. <b>Registration:</b> The protocol of the previous version of this review was registered with the International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD42018093671.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37596349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience and perceptions of Social Prescribing interventions; a qualitative study with people with long-term conditions, link workers and health care providers","authors":"Declan J. O'Sullivan, Lindsay M. Bearne, Janas M. Harrington, Joseph G. McVeigh","doi":"10.12688/hrbopenres.13762.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13762.2","url":null,"abstract":"<ns3:p>Background Long-term conditions (LTC) are a leading cause of reduced quality of life and early mortality. People with LTC are living longer with increasing economic and social needs. Novel patient centred care pathways are required to support traditional medical management of these patients. Social Prescribing (SP) has gained popularity as a non-medical approach to support patients with LTC and their unmet health needs. The current focus group study aims to explore the experiences and perceptions to SP interventions from the perspective of people with long-term conditions, link workers, healthcare providers and community-based services. Methods Six-eight participants will be recruited into three specific 60-minute focus groups relative to their role as a patient, link worker and community-based service. Eight-12 participants with a Health care provider and GP background will be interviewed individually online. The participants within these focus groups and semi-structured interviews will be invited to provide opinions on what factors they think are important to the successful implementation of a SP service from their respective stakeholder positions. The data will be recorded and exported to NVivo software for further analysis using Thematic Reflexive analysis methods. Coded categorical data will inform emerging themes from which a narrative summary will be consolidated and presented for dissemination. Conclusion The conclusions made from this study will help inform the next study, which will aim to develop a pilot SP service for patients with long-term musculoskeletal conditions as part of an overall larger project.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135969564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of COVID-19 vaccines for the treatment of people with post-COVID-19 condition: a rapid review","authors":"K.M. Saif-Ur-Rahman, Kavita Kothari, Corinna Sadlier, Frank Moriarty, Ani Movsisyan, Sean Whelan, Petek Eylul Taneri, Matthew Blair, Gordon Guyatt, Declan Devane","doi":"10.12688/hrbopenres.13638.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13638.2","url":null,"abstract":"<ns3:p><ns3:bold>Background:</ns3:bold> Vaccination for coronavirus disease 2019 (COVID-19) has demonstrated reduced risk of hospitalisation and death against more recent variants of COVID-19. Some studies suggested improvements in patients with post-COVID-19 condition (PCC) following vaccination. We systematically explored available evidence on the effect of COVID-19 vaccines on the treatment of people with PCC. <ns3:bold>Methods:</ns3:bold> We conducted a rapid review of the literature following systematic approaches. We searched Medline (OVID), EMBASE (Elsevier), ClinicalTrials.gov, and the International Clinical Trials Registry Platform (ICTRP) for randomised trials, non-randomised trials, controlled before-after studies, and interrupted time-series studies of the effect of COVID-19 vaccines for treating people with PCC. Two independent review authors screened citations. Two review authors extracted data independently. We had planned to assess the risk of bias and use the GRADE approach (Grading of Recommendations, Assessment, Development, and Evaluation) to assess the certainty of evidence if there were completed studies. <ns3:bold>Results:</ns3:bold> We identified two ongoing randomised controlled trials. Both trials examine the effectiveness of therapeutic vaccines on PCC. The anticipated completion date of the CIMAvax-EGFA trial is January 2023, and the completion date of the COVID-19 mRNA vaccine trial is not stated. <ns3:bold>Conclusions:</ns3:bold> There is currently an absence of high‐quality evidence evaluating the effectiveness of COVID-19 vaccines for treating people with post-COVID-19 condition. The absence of published studies and only two ongoing trials highlight the need for additional studies on the effectiveness of vaccines for PCC. We recommend that researchers consider PCC as per the definition provided by the World Health Organization and use the available core outcome set for PCC in deciding which outcomes to measure and report in the trials. <ns3:bold>PROPSERO registration:</ns3:bold> CRD42022330821 (20/06/2022)</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136209007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting perineal trauma during childbirth using data from a general obstetric population.","authors":"Gillian M Maher, Laura J O'Byrne, Joye McKernan, Paul Corcoran, Richard A Greene, Ali S Khashan, Fergus P McCarthy","doi":"10.12688/hrbopenres.13656.2","DOIUrl":"10.12688/hrbopenres.13656.2","url":null,"abstract":"<p><strong>Background: </strong>Perineal trauma is a common complication of childbirth and can have serious impacts on long-term health. Few studies have examined the combined effect of multiple risk factors. We developed and internally validated a risk prediction model to predict third and fourth degree perineal tears using data from a general obstetric population.</p><p><strong>Methods: </strong>Risk prediction model using data from all singleton vaginal deliveries at Cork University Maternity Hospital (CUMH), Ireland during 2019 and 2020. Third/fourth degree tears were diagnosed by an obstetrician or midwife at time of birth and defined as tears that extended into the anal sphincter complex or involved both the anal sphincter complex and anorectal mucosa. We used univariable and multivariable logistic regression with backward stepwise selection to develop the models. Candidate predictors included infant sex, maternal age, maternal body mass index, parity, mode of delivery, birthweight, post-term delivery, induction of labour and public/private antenatal care. We used the receiver operating characteristic (ROC) curve C-statistic to assess discrimination, and bootstrapping techniques were used to assess internal validation.</p><p><strong>Results: </strong>Of 8,403 singleton vaginal deliveries, 8,367 (99.54%) had complete data on predictors for model development. A total of 128 women (1.53%) had a third/fourth degree tear. Three variables remained in the final model: nulliparity, mode of delivery (specifically forceps delivery or ventouse delivery) and increasing birthweight (per 100 gram increase) (C-statistic: 0.75, 95% CI: 0.71, 0.79). We developed a nomogram to calculate individualised risk of third/fourth degree tears using these predictors. Bootstrapping indicated good internal performance.</p><p><strong>Conclusions: </strong>Use of our nomogram can provide an individualised risk assessment of third/fourth degree tears and potentially aid counselling of women on their potential risk.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communication partner training for student health and social care professionals engaging with people with stroke acquired communication difficulties: A realist review.","authors":"Yvonne Fitzmaurice, Suzanne Beeke, Jytte Isaksen, Una Cunningham, Caroline Jagoe, Éidín Ní Shé, Ruth McMenamin","doi":"10.12688/hrbopenres.13783.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13783.1","url":null,"abstract":"<ns3:p><ns3:bold>Background: </ns3:bold>Stroke acquired communication impairments impede effective communication. Consequently, in stroke care, communicative interactions can be challenging for both patients and staff and can predispose patients to increased risk of preventable adverse events. Communication partner training (CPT) can mitigate such negative outcomes by optimising communicative interactions. Providing CPT to student health and social care professionals (SH&amp;SCPs) has the potential to enhance their clinical expertise and experiences and enhance the future clinical care of patients with stroke acquired communication impairments. This research aims to expand our understanding of how CPT is operationalised for SH&amp;SCPs in higher education institutions and determine: what works; for whom; in what contexts; how and why?</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> This review is phase 1 of a research project employing a realist approach with public and patient involvement (PPI). It incorporates five iterative steps: 1.) Clarifying the scope; 2.) Searching for evidence; 3.) Selecting and appraising evidence; 4.) Data extraction; 5.) Synthesising data and developing a middle range theory explaining how CPT is expected to work for SH&amp;SCPs. An advisory group, including PPI advisors, content experts, SH&amp;SCPs and realist experts has been set up to consult throughout the review and collaboratively agree the middle range theory.</ns3:p><ns3:p> <ns3:bold>Discussion:</ns3:bold> While there is an evolving evidence base for CPT, including stroke specific CPT for SH&amp;SCPs, it is acknowledged that there are challenges to its implementation in complex real-world settings. In combining empirical evidence with theoretical understanding, realist review permits synthesis of data from diverse sources and goes beyond determining efficacy to explore generative causation and solutions for real world practice. A middle range realist programme theory that coherently explains how CPT is expected to work when teaching SH&amp;SCPs to communicate with people with stroke acquired communication impairments will provide educators with new insights into CPT development and implementation in their higher education institutions.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136296280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a core outcome set (COS) for Dementia with Lewy bodies (DLB).","authors":"Emilia Grycuk,&nbsp;Emily Eichenholtz,&nbsp;Dag Aarsland,&nbsp;Sara Betzhold,&nbsp;Gillian Daly,&nbsp;Ann-Kristin Folkerts,&nbsp;Elke Kalbe,&nbsp;Joseph Pm Kane,&nbsp;Irina Kinchin,&nbsp;Ian Saldanha,&nbsp;Valerie Smith,&nbsp;John-Paul Taylor,&nbsp;Rachel Thompson,&nbsp;Iracema Leroi","doi":"10.12688/hrbopenres.13590.2","DOIUrl":"10.12688/hrbopenres.13590.2","url":null,"abstract":"<p><p><b>Background:</b> Dementia with Lewy bodies (DLB) is an important cause of dementia with a range of clinical manifestations, including motor, neuropsychiatric, and autonomic symptoms. Compared with more common forms of dementia such as Alzheimer's disease, DLB has been the focus of significantly fewer treatment studies, often with diverse outcome measures, making comparison and clinical implementation difficult. A core outcome set (COS) can address this by ensuring that data are comparable, relevant, useful, and usable for making the best healthcare decisions. <b>Methods:</b> Using a multi-stage approach, development of the DLB-COS will include the following stages: (1) A systematic review, following PRISMA guidelines to create an initial long list of outcomes; (2) A two-round online Delphi including clinicians, scientists, policymakers, and individuals with lived experience of DLB and their representatives; (3) An online consensus meeting to agree on the final core list of outcomes (the final DLB-COS) for use in research and clinical practice; (4) A systematic review to identify appropriate measurement instruments for the DLB-COS outcomes; (5) A final consensus meeting of the professional stakeholders who attended the online consensus meeting to agree on the instruments that should be used to measure the outcomes in the DLB-COS; and (6) Global dissemination. <b>Discussion:</b> This is a multi-stage project to develop a COS to be used in treatment trials for DLB. A DLB-COS will ensure the selection of relevant outcomes and will identify the instruments to be used to measure DLB globally. <b>Keywords</b>: Dementia, Dementia with Lewy Bodies, Core Outcome Set, Delphi, Systematic Review, Ageing, Cognition, Memory.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41222243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence for using point-of-care diagnostics in the management of respiratory tract infections in primary care: a scoping review protocol","authors":"Judith Cole, Carmel Hughes, Cathal Cadogan, Akke Vellinga, Gerard Molloy, Tom Fahey, Greg Sheaf, Anthony Maher, Cristin Ryan","doi":"10.12688/hrbopenres.13770.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13770.1","url":null,"abstract":"<ns4:p><ns4:bold>Background: </ns4:bold>Antimicrobial resistance (AmR) is widely considered a global health threat and is associated with significant morbidity, mortality and costs. Inappropriate antimicrobial use is the most important modifiable risk factor for AmR. Most human antimicrobial medicines use occurs in primary care [prescribed by general practitioners (GPs), dispensed by community pharmacists (CPs)]. However, up to 50% of use is deemed inappropriate. Point-of-care diagnostic tests are used as a basis for antimicrobial stewardship interventions to improve the diagnostic certainty of respiratory tract infections (RTIs), and therefore ensure prudent antimicrobial use. However, there is a lack of guidance on their use, and they are therefore not routinely used in clinical practice.</ns4:p><ns4:p> <ns4:bold>Objective: </ns4:bold>A scoping review will be conducted to synthesise the available evidence to inform the development of best practice guidance for using point-of-care diagnostics in the management of RTIs in primary care.</ns4:p><ns4:p> <ns4:bold>Methods: </ns4:bold>A scoping review will be conducted following guidance from the Joanna Briggs Institute (JBI) and reported using the PRISMA-ScR guidelines. Databases including Web of Science, MEDLINE, CINAHL, EMBASE, the International HTA database and the Cochrane Central Register of Controlled Trials, as well as grey literature, will be searched. Screening will be undertaken independently by two reviewers to identify studies and literature reporting the use of point-of-care diagnostics in the management of RTIs in primary care by GPs and/ or CPs. Findings will be described using narrative synthesis.</ns4:p><ns4:p> <ns4:bold>Conclusion: </ns4:bold>The findings of this scoping review will be used to produce draft guidance on the use of point-of-care diagnostic tests in primary care, which will undergo further development using a Delphi consensus methodology involving experts in the field of RTIs, antimicrobial stewardship, point-of-care diagnostics and primary care.</ns4:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135814623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rehabilitation needs of people with brain tumours in Ireland: Protocol for a prospective, mixed methods action research study (“Brain-RESTORE”)","authors":"Ailish Malone, Bernadine O'Donovan, Paul Carroll, Sarah Donnelly, Eloise Cowie, Liam Grogan, Stephen MacNally, Mary O'Sullivan, Jan Sorenson, Eoin J. Tiernan, Rory J. O'Connor, John MacFarlane, Sorcha O'Keeffe, Andrew W. Murphy, Fiona Keegan, Frances Horgan, Kathleen Bennett","doi":"10.12688/hrbopenres.13786.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13786.1","url":null,"abstract":"<ns3:p><ns3:bold>Background:</ns3:bold> Approximately 480 people annually in Ireland are diagnosed with a primary brain tumour. Brain tumours are a heterogeneous group of conditions, varying in histopathology, location, and progression. A consistent feature is neurological impairment, which can lead to profound effects on physical and cognitive function. There is evidence that people with brain tumours can benefit from rehabilitation, but pathways are poorly described, and no best practice is defined. This leads to significant unmet need. The aim of this study is to understand the rehabilitation needs of people diagnosed with a brain tumour in Ireland, and gain insight to inform policy and practice.</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> A prospective, mixed methods study with embedded action research will be conducted. Patients (n=122) with a new diagnosis of primary brain tumour, and optionally, a nominated carer or family member, will be recruited through a national neuro-oncology service. Rehabilitation need (Mayo-Portland Adaptability Inventory), quality of life (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Brain Cancer Module, EuroQol-5D-5L), healthcare utilisation and, optionally, carer needs (Carer Support Needs Assessment Tool) will be assessed at four, eight and 12 months post diagnosis. An embedded qualitative study will invite 30 patients and carers to a semi-structured interview to explore their lived experience of rehabilitation needs and services following brain tumour diagnosis. Finally, using an Action Research approach, healthcare professionals involved in caring for people with brain tumours will be invited to participate in co-operative inquiry groups, to reflect on emerging aggregate findings and identify actions that could be undertaken while the study is underway.</ns3:p><ns3:p> <ns3:bold>Conclusions:</ns3:bold> By understanding rehabilitation need, the findings will help healthcare professionals and health service providers understand how to prioritise the supports required and encourage policy makers to adequately resource neurorehabilitation to meet the needs of people with a brain tumour diagnosis.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135815308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing men's awareness of testicular diseases (E-MAT) feasibility trial: Protocol for a mixed method process evaluation","authors":"Josephine Hegarty, Megan McCarthy, Martin Davoren, Frances Shiely, Janas M. Harrington, Gillian Shorter, David Murphy, Eoghan Cooke, Billy O'Mahony, Mohamad M. Saab","doi":"10.12688/hrbopenres.13515.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13515.2","url":null,"abstract":"<ns3:p><ns3:bold>Background</ns3:bold>: Testicular cancer (TC) is the most common malignancy in men under 50 years. Athletes are particularly at risk of testicular trauma and diseases. Experiencing negative testicular symptoms does not necessarily imply that men seek help. Men’s awareness of testicular diseases is often lacking and their intention to seek help for testicular symptoms is sub-optimal. The use of virtual reality (VR) may be effective in promoting men’s awareness of testicular diseases.</ns3:p><ns3:p> The Enhancing Men's Awareness of Testicular diseases (E-MAT) feasibility trial aims to test the effect of E-MAT<ns3:sub>VR </ns3:sub>(intervention; interactive experience using virtual reality [VR]) compared to information delivered Electronically E-MAT<ns3:sub>E</ns3:sub> (control; same information as E-MAT<ns3:sub>VR </ns3:sub>delivered as plain text and images) on testicular knowledge, and testicular self-examination among male athletes affiliated with a national sports organisation.</ns3:p><ns3:p> The overall aim of this mixed method process evaluation will be to describe (i) the experiences of participants and key stakeholders (e.g., researchers); (ii) the perceived effectiveness of intervention components; (iii) acceptability of the feasibility trial and intervention procedures; (iv) the relationship between implementation, mechanisms, and context; and (v) the barriers and facilitators to support effective conduct of a future definitive trial. </ns3:p><ns3:p> <ns3:bold>Methods: </ns3:bold>This mixed method process evaluation will use a descriptive realist evaluation. Quantitative data will be gathered using a usability and satisfaction survey, in addition to fidelity checks during intervention delivery. Quantitative data will be analysed using descriptive and inferential statistics. Qualitative data will be gathered from semi-structured interviews and focus groups with participants and key stakeholders to investigate their experiences of E-MAT<ns3:sub>VR</ns3:sub> and E-MAT<ns3:sub>E</ns3:sub>, and explore areas for improvement. Thematic analysis of transcripts will be conducted.</ns3:p><ns3:p> <ns3:bold>Conclusions: </ns3:bold>This process evaluation will provide an in-depth understanding of how the interventions worked within this cohort and lessons for a future definitive trial.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136061881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}