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Interventions to support adolescents and young adults with the healthcare transition from paediatric to adult nephrology health services: A scoping review protocol 干预措施,以支持青少年和年轻人的医疗保健过渡从儿科到成人肾健康服务:范围审查协议
HRB open research Pub Date : 2023-10-30 DOI: 10.12688/hrbopenres.13684.3
Melissa Kinch, Thilo Kroll, Diarmuid Stokes, Suja Somanadhan
{"title":"Interventions to support adolescents and young adults with the healthcare transition from paediatric to adult nephrology health services: A scoping review protocol","authors":"Melissa Kinch, Thilo Kroll, Diarmuid Stokes, Suja Somanadhan","doi":"10.12688/hrbopenres.13684.3","DOIUrl":"https://doi.org/10.12688/hrbopenres.13684.3","url":null,"abstract":"<ns4:p>Background Due to technological advancements and improved medical management of adolescents and young adults (AYAs) living with renal disease, there has been an exponential increase noted in the number of patients advancing from the paediatric to the adult nephrology healthcare setting. Subsequently, more AYAs are required to undergo the process of healthcare transition from paediatric to adult healthcare services. This process can be challenging period for young people and families and is often associated with a decline in physical and psychosocial health outcomes of AYAs with renal disorders. To ensure a successful transition, AYAs must develop the ability to manage their renal condition, including the medical and psychosocial aspects of their condition, independently. Despite significant research into the transition from paediatric to adult healthcare for this unique patient cohort, the transition period remains a challenge at times. This scoping review aims to map, explore, and understand the interventions that are currently available to offer positive perceptions and experiences of transition for both AYAs living with renal disorders and their families. Methods A systematic literature search will be conducted of PubMed, PsycInfo, CINAHL, ASSIA, EMBASE and Web of Science databases from the year 2000 to present. Two independent reviewers will screen the peer-reviewed literature obtained and assess them against the inclusion criteria to determine their inclusion eligibility. Data will be extracted and synthesised using a template refined by the authors. The scoping review will be undertaken in accordance with PRISMA-ScR guidelines. Data will undergo a formal critical appraisal using recognised appraisal tools. Conclusions Through mapping this knowledge, the scoping review will aim to identify interventions that are currently available and identify gaps within the literature. This evidence may support the development of transitional care interventions in the future, promote patient satisfaction, and improve patient outcome measures and experiences.</ns4:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136103326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventions to support adolescents and young adults with the healthcare transition from paediatric to adult nephrology health services: A scoping review protocol. 支持青少年和年轻人从儿科健康服务向成人肾脏病健康服务过渡的干预措施:范围界定审查协议。
HRB open research Pub Date : 2023-10-30 eCollection Date: 2023-01-01 DOI: 10.12688/hrbopenres.13684.2
Melissa Kinch, Thilo Kroll, Diarmuid Stokes, Suja Somanadhan
{"title":"Interventions to support adolescents and young adults with the healthcare transition from paediatric to adult nephrology health services: A scoping review protocol.","authors":"Melissa Kinch,&nbsp;Thilo Kroll,&nbsp;Diarmuid Stokes,&nbsp;Suja Somanadhan","doi":"10.12688/hrbopenres.13684.2","DOIUrl":"10.12688/hrbopenres.13684.2","url":null,"abstract":"<p><strong>Background: </strong>Due to technological advancements and improved medical management of adolescents and young adults (AYAs) living with renal disease, there has been an exponential increase noted in the number of patients advancing from the paediatric to the adult nephrology healthcare setting. Subsequently, more AYAs are required to undergo the process of healthcare transition from paediatric to adult healthcare services. This process can be a challenging period for young people and families and is often associated with a decline in physical and psychosocial health outcomes of AYAs with renal disorders. To ensure a successful transition, AYAs must develop the ability to manage their renal condition, including the medical and psychosocial aspects of their condition, independently. Despite significant research into the transition from paediatric to adult healthcare for this unique patient cohort, the transition period remains a challenge at times. This scoping review aims to map, explore, and understand the interventions that are currently available to offer positive perceptions and experiences of transition for both AYAs living with renal disorders and their families.</p><p><strong>Methods: </strong>A systematic literature search will be conducted of PubMed, PsycInfo, CINAHL, ASSIA, EMBASE and Web of Science databases from the year 2000 to present. Two independent reviewers will screen the peer-reviewed literature obtained and assess them against the inclusion criteria to determine their inclusion eligibility. Data will be extracted and synthesised using a template refined by the authors. The scoping review will be undertaken in accordance with PRISMA-ScR guidelines. Data will undergo a formal critical appraisal using recognised appraisal tools.</p><p><strong>Conclusions: </strong>Through mapping this knowledge, the scoping review will aim to identify interventions that are currently available and identify gaps within the literature. This evidence may support the development of transitional care interventions in the future, promote patient satisfaction, and improve patient outcome measures and experiences.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10406192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of telemedicine enabled pre-hospital triage in acute stroke - a protocol for a mixed methods systematic review. 远程医疗对急性中风院前分诊的影响——一项混合方法系统评价的协议。
HRB open research Pub Date : 2023-10-30 eCollection Date: 2022-01-01 DOI: 10.12688/hrbopenres.13514.2
Deirdre McCartan, Stuart Lee, Jorin Bejleri, Paul Murphy, Anne Hickey, David Williams
{"title":"The impact of telemedicine enabled pre-hospital triage in acute stroke - a protocol for a mixed methods systematic review.","authors":"Deirdre McCartan, Stuart Lee, Jorin Bejleri, Paul Murphy, Anne Hickey, David Williams","doi":"10.12688/hrbopenres.13514.2","DOIUrl":"10.12688/hrbopenres.13514.2","url":null,"abstract":"<p><strong>Introduction: </strong>Increasing access to thrombolysis and thrombectomy through improved pathway organisation remains a health service challenge that requires contextualisation to the geographic, demographic and resourcing status of any regional stroke service. Pre-hospital delays or delays during inter-hospital transfers can result in patients being outside the window for one or both interventions. Pre-hospital triage using technology-enabled interdisciplinary communication networks may facilitate rapid individualized care decisions, permitting streamlined care pathways to hospital sites most appropriate to their clinical presentation and history in the first instance. Understanding the experience of those involved in efforts to improve or reorganise care may help to explain the impact observed.</p><p><strong>Objectives: </strong>1. To review the impact of pre-hospital telemedicine enabled workflow intervention strategies on patient outcomes and on service process metrics in hyper-acute stroke care2. To examine how the experience of those involved in providing or receiving such interventions might identify key characteristics of effective interventions.</p><p><strong>Inclusion criteria: </strong>Quantitative, qualitative and primary mixed methods studies will be included. Quantitative studies will assess effectiveness of telemedicine-enabled interventions that facilitate pre-hospital acute stroke triage. Intervention effects on functional outcomes of patients, on intervention rates and on key time metrics in hyperacute stroke care will be assessed. Qualitative studies will explore the experiences of people involved in or impacted by these interventions.</p><p><strong>Methods and analysis: </strong>A convergent segregated mixed methods systematic review will synthesise and integrate primary qualitative, quantitative and mixed methods studies using the Joanna Briggs Institute methodology. Database searches will include OVID (MEDLINE), EMBASE, The Cochrane Library, CINAHL and Web of Science. Critical appraisal will include the Mixed Methods Assessment Tool. Results of quantitative studies and findings of qualitative studies will be integrated and configured to explore and contextualize each single method synthesis.</p><p><strong>Systematic review registration: </strong>This protocol has been submitted for registration with PROSPERO.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspectives and factors associated with informal human milk sharing: a mixed-methods systematic review protocol 与非正式母乳共享相关的观点和因素:一种混合方法的系统评价方案
HRB open research Pub Date : 2023-10-25 DOI: 10.12688/hrbopenres.13718.2
Niamh Vickers, Anne Matthews, Gillian Paul
{"title":"Perspectives and factors associated with informal human milk sharing: a mixed-methods systematic review protocol","authors":"Niamh Vickers, Anne Matthews, Gillian Paul","doi":"10.12688/hrbopenres.13718.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13718.2","url":null,"abstract":"<ns4:p>Background The practice of informal human milk sharing is a relatively new phenomenon and poses significant questions in the domain of infant feeding. Informal human milk sharing is a means of donating human milk from another lactating individual who is not the child’s biological parent, in a casual manner, that is, without the involvement of health professionals or agencies. The advent of digital technology has facilitated the donation and receipt of human milk through digital online platforms and thus has amplified this modern practice. This research aims to comprehensively examine and synthesize evidence about the motivations, barriers, facilitators and experiences of individuals who both donate (donors) and the primary care givers of the infants who receive (recipients) human milk informally to provide to infants. Methods A mixed-methods systematic review will be undertaken. This review will consider qualitative, quantitative and primary mixed-methods studies which report on the factors associated with informal milk sharing, and on donors’ and recipients’ experiences of the practice. Primary mixed-method studies will be included if the individual qualitative and quantitative components can be extracted. Five databases will be searched for studies on informal human milk sharing published from inception of the database. Study quality will be evaluated using the standardized JBI critical appraisal tools, selected based on the methodology in each individual study. Data extraction will be conducted using the JBI mixed methods data extraction form followed by data transformation, synthesis and integration. This mixed-methods systematic review will follow a convergent integrated approach in accordance with JBI guidance. Discussion Informal human milk sharing is a novel practice in the domain of infant feeding. This review will enable a thorough understanding of this practice from both the donors and recipients’ perspective and will have implications for healthcare professionals, policy and future clinical decision-making. Protocol registration number PROSPERO CRD42023405653</ns4:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135113987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspectives and factors associated with informal human milk sharing: a mixed-methods systematic review protocol. 与非正式母乳共享相关的观点和因素:一项混合方法系统审查协议。
HRB open research Pub Date : 2023-10-25 eCollection Date: 2023-01-01 DOI: 10.12688/hrbopenres.13718.1
Niamh Vickers, Anne Matthews, Gillian Paul
{"title":"Perspectives and factors associated with informal human milk sharing: a mixed-methods systematic review protocol.","authors":"Niamh Vickers,&nbsp;Anne Matthews,&nbsp;Gillian Paul","doi":"10.12688/hrbopenres.13718.1","DOIUrl":"10.12688/hrbopenres.13718.1","url":null,"abstract":"<p><strong>Background: </strong>The practice of informal human milk sharing is a relatively new phenomenon and poses significant questions in the domain of infant feeding. Informal human milk sharing is a means of donating human milk from another lactating individual who is not the child's biological parent, in a casual manner, that is, without the involvement of health professionals or agencies. The advent of digital technology has facilitated the donation and receipt of human milk through digital online platforms and thus has amplified this modern practice. This research aims to comprehensively examine and synthesize evidence about the motivations, barriers, facilitators and experiences of individuals who both donate (donors) and the primary care givers of the infants who receive (recipients) human milk informally to provide to infants.</p><p><strong>Methods: </strong>A mixed-methods systematic review will be undertaken. This review will consider qualitative, quantitative and primary mixed-methods studies which report on the factors associated with informal milk sharing, and on donors' and recipients' experiences of the practice. Primary mixed-method studies will be included if the individual qualitative and quantitative components can be extracted. Five databases will be searched for studies on informal human milk sharing published from inception of the database. Study quality will be evaluated using the standardized JBI critical appraisal tools, selected based on the methodology in each individual study. Data extraction will be conducted using the JBI mixed methods data extraction form followed by data transformation, synthesis and integration. This mixed-methods systematic review will follow a convergent integrated approach in accordance with JBI guidance.</p><p><strong>Discussion: </strong>Informal human milk sharing is a novel practice in the domain of infant feeding. This review will enable a thorough understanding of this practice from both the donors and recipients' perspective and will have implications for healthcare professionals, policy and future clinical decision-making.</p><p><strong>Protocol registration number: </strong>PROSPERO CRD42023405653.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10207691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol. 妊娠和分娩并发症与孕产妇长期不良心理健康结局的关联:一项系统回顾和荟萃分析方案
HRB open research Pub Date : 2023-10-24 eCollection Date: 2023-01-01 DOI: 10.12688/hrbopenres.13660.3
Elizabeth O Bodunde, Daire Buckley, Eimear O'Neill, Gillian M Maher, Karen Matvienko-Sikar, Karen O'Connor, Fergus P McCarthy, Ali S Khashan
{"title":"Pregnancy and birth complications associations with long-term adverse maternal mental health outcomes: a systematic review and meta-analysis protocol.","authors":"Elizabeth O Bodunde, Daire Buckley, Eimear O'Neill, Gillian M Maher, Karen Matvienko-Sikar, Karen O'Connor, Fergus P McCarthy, Ali S Khashan","doi":"10.12688/hrbopenres.13660.3","DOIUrl":"10.12688/hrbopenres.13660.3","url":null,"abstract":"<p><strong>Background: </strong>Existing studies have established an association between pregnancy, birth complications, and mental health in the first few weeks postpartum. However, there is no clear understanding of whether pregnancy and birth complications increase the risk of adverse maternal mental outcomes in the longer term. Research on maternal adverse mental health outcomes following pregnancy and birth complications beyond 12 months postpartum is scarce, and findings are inconsistent.</p><p><strong>Objective: </strong>This systematic review and meta-analysis will examine the available evidence on the association between pregnancy and birth complications and long-term adverse maternal mental health outcomes.</p><p><strong>Methods and analysis: </strong>We will include cohort, cross-sectional, and case-control studies in which a diagnosis of pregnancy and/or birth complication (preeclampsia, pregnancy loss, caesarean section, preterm birth, perineal laceration, neonatal intensive care unit admission, major obstetric haemorrhage, and birth injury/trauma) was reported and maternal mental disorders (depression, anxiety disorders, bipolar disorders, psychosis, and schizophrenia) after 12 months postpartum were the outcomes. A systematic search of PubMed, Embase, CINAHL, PsycINFO, and Web of Science will be conducted following a detailed search strategy until August 2022. Three authors will independently review titles and abstracts of all eligible studies, extract data using pre-defined standardised data extraction and assess the quality of each study using the Newcastle-Ottawa Scale. We will use random-effects meta-analysis for each exposure and outcome variable to calculate overall pooled estimates using the generic inverse variance method. This systematic review will follow the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines.</p><p><strong>Ethical consideration: </strong>The proposed systematic review and meta-analysis is based on published data; ethics approval is not required. The results will be presented at scientific meetings and publish in a peer-reviewed journal.</p><p><strong>Prospero registration: </strong>CRD42022359017.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between intrapartum fetal pulse oximetry and adverse perinatal and long-term outcomes: a systematic review and meta-analysis protocol 产时胎儿脉搏血氧测定与不良围产期和长期预后之间的关系:一项系统综述和荟萃分析方案
HRB open research Pub Date : 2023-10-20 DOI: 10.12688/hrbopenres.13802.1
Jill M. Mitchell, Siobhan Walsh, Laura J. O'Byrne, Virginia Conrick, Ray Burke, Ali S. Khashan, John Higgins, Richard Greene, Gillian M. Maher, Fergus P. McCarthy
{"title":"Association between intrapartum fetal pulse oximetry and adverse perinatal and long-term outcomes: a systematic review and meta-analysis protocol","authors":"Jill M. Mitchell, Siobhan Walsh, Laura J. O'Byrne, Virginia Conrick, Ray Burke, Ali S. Khashan, John Higgins, Richard Greene, Gillian M. Maher, Fergus P. McCarthy","doi":"10.12688/hrbopenres.13802.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13802.1","url":null,"abstract":"<ns7:p><ns7:bold>Background:</ns7:bold> Current methods of intrapartum fetal monitoring based on heart rate, increase the rates of operative delivery but do not prevent or accurately detect fetal hypoxic brain injury. There is a need for more accurate methods of intrapartum fetal surveillance that will decrease the incidence of adverse perinatal and long-term neurodevelopmental outcomes while maintaining the lowest possible rate of obstetric intervention. Fetal pulse oximetry (FPO) is a technology that may contribute to improved intrapartum fetal wellbeing evaluation by providing a non-invasive measurement of fetal oxygenation status.</ns7:p><ns7:p> <ns7:bold>Objective:</ns7:bold> This systematic review and meta-analysis aims to synthesise the evidence examining the association between intrapartum fetal oxygen saturation levels and adverse perinatal and long-term outcomes in the offspring.</ns7:p><ns7:p> <ns7:bold>Methods:</ns7:bold> We will include randomised control trials (RCTs), cohort, cross-sectional and case-control studies which examine the use of FPO during labour as a means of measuring intrapartum fetal oxygen saturation and assess its effectiveness at detecting adverse perinatal and long-term outcomes compared to existing intrapartum surveillance methods. A detailed systematic search of PubMed, EMBASE, CINAHL, The Cochrane Library and Web of Science will be conducted following a detailed search strategy until August 2023. Three authors will independently review titles, abstracts and full text of articles. Two reviewers will independently extract data using pre-defined data extraction and assess the quality using the Risk of Bias tool for RCTs and Newcastle-Ottawa Scale for observational studies. We will use random-effects meta-analysis for each exposure-outcome association to calculate pooled estimates using the generic variance method. This systematic review will follow the Preferred Reporting Items for Systematic reviews and Meta-analyses guidelines.</ns7:p><ns7:p> <ns7:bold>PROSPERO registration:</ns7:bold> CRD42023457368 (04/09/2023)</ns7:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135569472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of dietary fiber on gut microbiota composition, function and gut-brain-modules in healthy adults – a systematic review protocol 膳食纤维对健康成人肠道微生物群组成、功能和肠-脑模块的影响——一项系统评价方案
HRB open research Pub Date : 2023-10-20 DOI: 10.12688/hrbopenres.13794.1
David Antoine Lachmansingh, Benjamin Valderrama, Thomaz Bastiaanssen, John Cryan, Gerard Clarke, Aonghus Lavelle
{"title":"Impact of dietary fiber on gut microbiota composition, function and gut-brain-modules in healthy adults – a systematic review protocol","authors":"David Antoine Lachmansingh, Benjamin Valderrama, Thomaz Bastiaanssen, John Cryan, Gerard Clarke, Aonghus Lavelle","doi":"10.12688/hrbopenres.13794.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13794.1","url":null,"abstract":"<ns3:p><ns3:bold><ns3:underline>Background</ns3:underline></ns3:bold>: The gut microbiota has been extensively implicated in health and disease. The functional outputs of the gut microbiota, such as microbial metabolites, are considered particularly important in this regard. Significant associations exist between alterations in the relative abundance of specific microbial taxa and mental health disorders. Dietary fiber has the potential to alter gut microbiota composition and function, modifying bacterial enzymatic function and the production of metabolites. As many taxa of microorganisms have enzymes capable of producing or degrading neurochemicals i.e. neuroactive gut brain modules, new predictive tools can be applied to existing datasets such as those harvested from dietary fiber interventions. We endeavor to perform a systematic review in order to identify studies reporting compositional gut microbiota alterations after interventions with dietary fiber in healthy individuals. We aim to also extract from the selected studies publicly available microbial genomic sequence datasets for reanalysis with a consistent bioinformatics pipeline, with the ultimate intention of identifying altered gut brain modules following dietary fiber interventions.</ns3:p><ns3:p> <ns3:bold><ns3:underline>Methods</ns3:underline></ns3:bold>: Interventional trials and randomized controlled studies that are originally published, including cross-over and non-crossover design and involving healthy adult humans will be included. A systematic search of PubMed/MEDLINE and EMBASE, two electronic databases, will be completed.</ns3:p><ns3:p> <ns3:bold><ns3:underline>Discussion</ns3:underline></ns3:bold>: Various types of dietary fiber have an impact on the gut microbiota composition, with some promoting the growth of particular taxa while others are reduced in relative abundance. Our search focuses on the impact of this food component on the microbiota of healthy individuals. Compositional gut microbial changes have been reported and our review will compile and update these observations after reanalysis of their datasets with a consistent bioinformatic pipeline. From this it may be possible to predict more detailed functional consequences in terms of neuroactive gut brain modules, of the compositional alterations in gut microbial taxa.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135569768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2016-2021: A methodological report. 2017-2021年爱尔兰普通医疗服务计划人群的合格率和代表性:一份方法报告。
HRB open research Pub Date : 2023-10-18 eCollection Date: 2022-01-01 DOI: 10.12688/hrbopenres.13622.1
Molly Mattsson, Michelle Flood, Emma Wallace, Fiona Boland, Frank Moriarty
{"title":"Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2016-2021: A methodological report.","authors":"Molly Mattsson, Michelle Flood, Emma Wallace, Fiona Boland, Frank Moriarty","doi":"10.12688/hrbopenres.13622.1","DOIUrl":"10.12688/hrbopenres.13622.1","url":null,"abstract":"<p><strong>Background: </strong>In Ireland, the means tested General Medical Services (GMS) scheme provides access to a range of healthcare services at no or low cost to approximately one third of the population. Individuals eligible for the GMS scheme are often a focus of research, as a population that account for a large proportion of healthcare services use. The aim of this study is to describe the eligibility rates and representativeness of the GMS scheme population over time, with respect to age group, sex, and geographical area in Ireland.</p><p><strong>Methods: </strong>Population data was obtained from the Central Statistics Office (CSO), using 2016 Census figures and projected population figures for 2017-2021. GMS eligibility figures for 2016-2021 were obtained from the HSE Primary Care Reimbursement Service (PCRS). GMS eligibility rates and relative rates of eligibility were calculated for 2016-2021 by age group and sex. Additionally, 2016 eligibility rates were calculated by geographical area.</p><p><strong>Results: </strong>The crude eligibility rate decreased from 36.4% in 2016 to 31.2% in 2020, with a slight increase to 31.6% in 2021. In the 75+ years age group, 78.2% of the total population were eligible for the GMS scheme in 2021. The age group with the lowest rate of eligible individuals was the 25-34 age group, with 19.5% eligible in 2021. The eligibility rate was higher among females compared to males throughout the study period. The highest eligibility rate was seen in Donegal, with a crude rate of 52.8%. Dublin had the lowest rate, with a crude rate of 29.3%.</p><p><strong>Conclusions: </strong>GMS eligibility varies greatly depending on age, sex, and geographical area, and decreased between 2016 and 2021. This study uses the most up-to-date data available to provide age group, sex and area-based figures for GMS eligibility which may inform planning and conduct of research focusing on GMS-eligible individuals.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41146995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2016-2021: A methodological report 2016-2021年爱尔兰普通医疗服务计划人口的合格率和代表性:一份方法报告
HRB open research Pub Date : 2023-10-18 DOI: 10.12688/hrbopenres.13622.2
Molly Mattsson, Michelle Flood, Emma Wallace, Fiona Boland, Frank Moriarty
{"title":"Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2016-2021: A methodological report","authors":"Molly Mattsson, Michelle Flood, Emma Wallace, Fiona Boland, Frank Moriarty","doi":"10.12688/hrbopenres.13622.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13622.2","url":null,"abstract":"<ns3:p>Background In Ireland, the means tested General Medical Services (GMS) scheme provides access to a range of healthcare services at no or low cost to approximately one third of the population. Individuals eligible for the GMS scheme are often a focus of research, as a population that account for a large proportion of healthcare services use. The aim of this study is to describe the eligibility rates and representativeness of the GMS scheme population over time, with respect to age group, sex, and geographical area in Ireland. Methods Population data was obtained from the Central Statistics Office (CSO), using 2016 Census figures and projected population figures for 2017-2021. GMS eligibility figures for 2016-2021 were obtained from the HSE Primary Care Reimbursement Service (PCRS). GMS eligibility rates and relative rates of eligibility were calculated for 2016-2021 by age group and sex. Additionally, 2016 eligibility rates were calculated by geographical area. Results The crude eligibility rate decreased from 36.4% in 2016 to 31.2% in 2020, with a slight increase to 31.6% in 2021. In the 75+ years age group, 78.2% of the total population were eligible for the GMS scheme in 2021. The age group with the lowest rate of eligible individuals was the 25–34 age group, with 19.5% eligible in 2021. The eligibility rate was higher among females compared to males throughout the study period. The highest eligibility rate was seen in Donegal, with a crude rate of 52.8%. Dublin had the lowest rate, with a crude rate of 29.3%. Conclusions GMS eligibility varies greatly depending on age, sex, and geographical area, and decreased between 2016 and 2021. This study uses the most up-to-date data available to provide age group, sex and area-based figures for GMS eligibility which may inform planning and conduct of research focusing on GMS-eligible individuals.</ns3:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135883207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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