HRB open research最新文献

{"title":"Protocol for a systematic review and systems-based exploration of interventions to reduce medicines wastage","authors":"Áine Harris, Ryan Jayesinghe, Lorna Bonnici West, Derek Stewart, T. Grimes, Patrick Redmond","doi":"10.12688/hrbopenres.13800.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13800.1","url":null,"abstract":"Introduction A reduction in medicines wastage is an important objective in promoting appropriate use of finite resources. The objective of this systematic review is to both assess the effectiveness of interventions to reduce medicines wastage, and apply a systems based exploration of the factors affecting implementation of interventions. Methods A systematic review will be conducted following PRISMA reporting guidelines. Searches will be performed in Cumulated Index to Nursing and Allied Health Literature (CINAHL), Embase, Medline, PubMed, Science Citation Index, PsycInfo, Scopus, the Cochrane Library, grey literature, and trials registries. Data extraction and critical appraisal will be completed independently by two reviewers. If studies are sufficiently homogenous in terms of design and comparators, we will conduct a meta-analysis. Where this is not possible, we will provide a narrative synthesis of results grouping studies with similar interventions together. The barriers and enablers of the described interventions will then be analysed using the Systems Engineering Initiative in Patient Safety (SEIPS 101) model. Conclusions This review will describe the effectiveness of interventions to reduce medicines wastage and issues associated with their implementation in order to inform policy development and intervention implementation in the future. This will have the potential to reduce both the economic and environmental burden of medicines wastage on the health service. PROSPERO registration CRD42022335848 (12/06/2022)","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138617953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"mHealth clinical decision-making tools for maternal and perinatal health care in Sub-Saharan Africa: A systematic review protocol","authors":"Gaudensia A. Olomi, L. Cansdale, Simon Woodworth, Rachel Manongi, Pendo Mlay, Karen Yeates, Nicola West, Jane E. Hirst, Christopher Redman, M. Mahande, B. Mmbaga, A. Khashan","doi":"10.12688/hrbopenres.13799.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13799.1","url":null,"abstract":"Background Mobile health (mHealth) tools are increasingly being used in Sub-Saharan Africa (SSA) to improve the quality of health services. mHealth clinical decision-making tools have several established roles in maternal and perinatal healthcare including health surveillance, data collection and access to guidelines. The adoption of mHealth clinical decision-making tools in low-resource environments like SSA, as well as the lessons learnt from using them, have not yet been determined. As new mHealth technologies are quickly being evaluated and deployed in resource-poor settings, it is crucial to thoroughly analyse what has been accomplished in order to inform implementers and policy makers on the effectiveness of technology in evidence-based practice. Objective This study aims to synthesize the available evidence 1) on the use of mHealth clinical decision-making tools for maternal and perinatal care in SSA, and 2) whether these tools lead to improvements in the quality of maternal and perinatal care in SSA. Methods A systematic review of the literature will be performed to identify publications describing the use mHealth tools for maternal and perinatal clinical decision-making in SSA. PubMed, CINAHL, EMBASE, Global Health and Web of Science will be searched for relevant articles following a predetermined search strategy with no date restrictions. A limited grey literature search will also be carried out. Two independent reviewers will screen the articles. Pre-determined data items will be extracted, and data synthesis carried out using a descriptive approach. Appraisal will be done using the Appraisal of Guidelines Research and Evaluation Health Systems (AGREE-HS) instrument. Conclusions This systematic review protocol for identifying and appraising mHealth clinical decision-making tools in maternal and perinatal care may help to establish best practice for developing and scaling up, thus help to improve care in SSA. Registration PROSPERO (CRD42023452760; 19 August 2023).:","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"77 8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Which outcome measurement instruments are used to measure core infant feeding outcomes in children up to 1 year of age? A scoping review protocol","authors":"K. Matvienko-Sikar, Linda Adair, Lucinda K Bell, C. Birken, Vicki Brown, Darren Dahly, A. Doherty, Rebecca K Golley, Patricia Leahy-Warren, Marian McBride, Elizabeth McCarthy, Andrew W Murphy, Sarah Redsell, C. B. Terwee","doi":"10.12688/hrbopenres.13797.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13797.1","url":null,"abstract":"Background How, what, and when infants are fed plays a role in the aetiology of childhood obesity. Heterogeneity in how infant feeding outcomes are measured in trials of interventions to prevent childhood obesity limits evidence syntheses and understanding of intervention effectiveness. An infant feeding core outcome set (COS) was previously developed to standardised outcome measurement and reporting. The COS represents what to measure; determining how best to measure these outcomes is the next essential step to improve intervention evaluations. The aim of this scoping review is therefore to identify what outcome measurement instruments have been used in trials, and how they have been used, to measure the core infant feeding outcomes. Methods A scoping review will be conducted. MEDLINE, EMBASE, CINAHL, PsychINFO, the Cochrane Central Register of Controlled Trials, OpenGrey and GreyNet will be searched from inception. Papers are eligible for inclusion if they report trials involving primary data collection that measure and report at least one core infant feeding outcome in infants ≤one year of age. Following searching and screening, eligible studies will be categorised into the following four overarching categories for data extraction, synthesis and write-up: caregiver-related outcomes; diet-related outcomes; feeding environment outcomes; child weight outcomes. Data will be narratively described and presented in tabular format, with findings presented in four separate review papers delineated by the four overarching categories. Discussion This scoping review forms part of the Standardised measurement for Childhood Obesity Prevention (SCOPE) study (www.eiascope.com). Evidence from this scoping review on what measurement instruments are used, and how they are used, represents an essential first step in developing recommendations and guidance about how best to measure core infant feeding outcomes for childhood obesity prevention. This can improve evidence syntheses and understanding of what infant feeding interventions are most effective for childhood obesity prevention.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age of first self-harm act in childhood and adolescence: A scoping review protocol.","authors":"Daisy Wiggin, Elaine McMahon, Fiona McNicholas, Eve Griffin","doi":"10.12688/hrbopenres.13764.2","DOIUrl":"10.12688/hrbopenres.13764.2","url":null,"abstract":"<p><strong>Background: </strong>Self-harm in youth is associated with adverse outcomes for many. The age of first self-harm is not often reported in the literature and there is considerable heterogeneity in how it is reported and in the methods used to estimate it. The objective of this study will be to examine the age of first self-harm act in childhood and adolescence and to identify the research methods used to assess this.</p><p><strong>Methods: </strong>This scoping review will follow JBI guidance. Five electronic databases, Medline, PsycInfo, CINAHL Plus, Embase, and Web of Science will be searched from inception. Grey literature will be searched via Google Scholar. Studies reporting the age of first act of self-harm in young people aged 17 years and younger are of interest. Any study design and methodology will be eligible for inclusion. Included studies may use any self-harm definition, any measures used to assess self-harm and the age of the first act. The focus can be in any context, including health services presenting or community samples. Title and abstract screening and full text screening will be carried out by two reviewers independently. The data extraction tool will be piloted by two reviewers independently, included studies will undergo data extraction by one reviewer and this will be checked by a second, independent reviewer.</p><p><strong>Results: </strong>The resulting data will be presented using descriptive statistics, in tabular format, and accompanied with a narrative presentation of results. The results of this study will be distributed by publication in an academic journal.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"36"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10714104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138814660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Quality, Use and Impact of Psychotropic (Use) in older adults with intellectual disabilities (EQUIP): study protocol","authors":"Ashleigh Gorman, Marina Odalović, P. McCallion, Eilish M Burke, Malcolm MacLachlan, M. McCarron, M. Henman, Maeve Moran, J. O’Connell, Mike Walsh, Rohit Shankar, M. O'Dwyer","doi":"10.12688/hrbopenres.13645.2","DOIUrl":"https://doi.org/10.12688/hrbopenres.13645.2","url":null,"abstract":"Widespread, and sometimes inappropriate use of psychotropics in adults with intellectual disability has been an international concern. These medicines have been used to treat mental health conditions, but also, controversially, some types of behaviours not necessarily associated with the diagnosis or in the absence of a relevant diagnosis. Results from the Intellectual Disability Supplement to the Irish Longitudinal Study on Ageing (IDS-TILDA) study of older adults with intellectual disability in Ireland revealed that 60% were taking psychotropics in 2010. In the intervening decade changes in regulations, policy, and increased decongregation of people with intellectual disability have taken place likely influencing the use of psychotropics. The HSE National Clinical Programme for People with Disability (NCPDD) established in the 2020 has medicines optimisation as a key priority. Existing multi-wave data from the IDS-TILDA study and the HSE national prescribing database offers an opportunity to better understand psychotropic use and prescribing patterns. This is a novel collaboration on lived experience, research, practice and policy. The aim of this research is to examine the quality and trends of psychotropic use of older adults with intellectual disability over a ten-year period in Ireland to evaluate the effects of and to inform both practice and policy to optimise medicines use and health outcomes. Health and medication data from ten years (four waves) of the IDS-TILDA study and corresponding medicines data from the HSE-PCRS prescribing database are available. Descriptive and longitudinal analysis will examine association between long-term psychotropic use, changes in trends of use, and the impact of decongregation on medicines use. This research will inform the development of national guidance on medicines optimisation for older people with intellectual disability and has the potential to change prescribing practices and improve health and wellbeing for older people with intellectual disability.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"36 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139250807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Definitions of serious injury in long-term residential care: a systematic review protocol","authors":"David Morrissey, Elizabeth A. O'Donnell, L. Behan, Martin McMahon, L. Keyes","doi":"10.12688/hrbopenres.13705.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13705.1","url":null,"abstract":"Background Evidence indicates that the reporting of serious injury in long-term residential care has increased substantially over the past decade. However, what constitutes a serious injury in residential care is poorly and inconsistently defined. This may result in incidences being unnecessarily reported as a serious injury. It is therefore, crucial to develop a consistent definition of serious injury to reduce reporting burden and to facilitate comparison between different residential care settings and across jurisdictions. This protocol describes the methods for a systematic review of existing definitions from the literature to inform the development of a consistent definition of serious injury in long-term residential care. Methods A wide range of published peer-reviewed and grey literature will be sought for this review, including guidance and policy documents. Searches will be conducted of databases including MEDLINE, CINAHL, SocINDEX, Academic Search Ultimate, and Westlaw International. Grey literature database searches will include Trip and Social Care Online. Country specific searches of government and health and social care websites will be conducted. Quality appraisal will be facilitated using the Quality Assessment for Diverse Studies (QuADS) tool and Tyndall’s checklist. The level of confidence in the findings will be assessed using the GRADE CERQual approach. A customised data extraction form will be used to extract data to reduce the risk of bias. Conceptual content analysis of data will facilitate identification of definitions of serious injury and their frequency within texts. Conclusion The findings will inform the development of a consistent definition of serious injury in long-term residential care that will reduce reporting burden, facilitate the accuracy of data collected and allow for comparison across jurisdictions. A more universal and consistent definition will enable regulators, policy makers, service providers and researchers to develop policy and practical interventions to prevent the occurrence of serious injury in long-term residential care.","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"274 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139256845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol Development for a Qualitative Methodological Study Within a Trial (Qual-SWAT): The KARMA-Dep-2 Trial.","authors":"John McCaffrey, Andrew Hunter","doi":"10.12688/hrbopenres.13721.2","DOIUrl":"10.12688/hrbopenres.13721.2","url":null,"abstract":"<p><strong>Background: </strong>Despite methodological improvements in clinical trial design and conduct more generally, methodological limitations persist in trials concerning mental health care. A qualitative Study Within A Trial (Qual-SWAT), embedded in the KARMA-Dep-2 host trial, will be undertaken to explore and gain an understanding of two methodological questions in randomised trials specific to mental health care: (1) what are the key barriers and enablers of participation in randomised trials in mental health; and (2) how can randomised trials become part of routine mental health care. These issues will be examined from patient-participant and clinician- / researcher-participant perspectives, in alignment with PRioRiTy research themes.</p><p><strong>Methods: </strong>A descriptive qualitative study design will be used. Data will be collected via one-to-one semi-structured interviews, conducted via Microsoft Teams. The interview data will be analysed using Braun and Clarke's Thematic Analysis approach. One-to-one interviews will be conducted with three participant groups ( <i>N</i> = 30): 1) host trial patient-participants ( <i>n</i> = 10); 2) potentially eligible host trial patient-participants who refused enrolment in the host trial ( <i>n</i> = 10); and 3) clinician- / researcher-participants who are associated with work on the host trial ( <i>n</i> = 10).</p><p><strong>Ethics and dissemination: </strong>Ethical approval has been granted by St. Patrick's Mental Health Services Research Ethics Committee, Ireland (Ref: Protocol 09/20). When the study is completed, a report will be prepared and submitted to the Health Research Board (HRB). Findings will be shared with the host trial team and study participants, and submitted for publication.</p><p><strong>Host trial registration: </strong>ClinicalTrials.gov ( NCT04939649); EudraCT ( 2019-003109-92). Official title: Ketamine as an Adjunctive Therapy for Major Depression - A Randomised Controlled Trial: [KARMA-Dep (2)].</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"6 ","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10074278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using behavioural science to enhance use of core outcome sets in trials: protocol.","authors":"Karen Matvienko-Sikar, Molly Byrne, Mike Clarke, Jamie Kirkham, Jan Kottner, Katie Mellor, Fiona Quirke, Ian J Saldanha, Valerie Smith, Elaine Toomey, Paula Williamson","doi":"10.12688/hrbopenres.13510.2","DOIUrl":"10.12688/hrbopenres.13510.2","url":null,"abstract":"<p><strong>Background: </strong>Core outcome sets (COS) represent agreed-upon sets of outcomes, which are the minimum that should be measured and reported in all trials in specific health areas. Use of COS can reduce outcome heterogeneity, selective outcome reporting, and research waste, and can facilitate evidence syntheses. Despite benefits of using COS, current use of COS in trials is low. COS use can be understood as a behaviour, in that it is something trialists do, or not do, adequately. The aim of this study is to identify strategies, informed by behaviour change theory, to increase COS use in trials.</p><p><strong>Methods: </strong>The project will be conducted in two stages, informed by the behaviour change wheel (BCW). The BCW is a theoretically based framework that can be used to classify, identify, and develop behaviour change strategies. In Stage 1, barriers and enablers to COS use will be extracted from published studies that examined trialist's use of COS. Barriers and facilitators will be mapped to the components of COM-B model (capability, opportunity, and motivation), which forms part of the BCW framework. Stage 2 will build on Stage 1 findings to identify and select intervention functions and behaviour change techniques to enhance COS use in trials.</p><p><strong>Discussion: </strong>The findings of this study will provide an understanding of the behavioural factors that influence COS use in trials and what strategies might be used to target these factors to increase COS use in trials.</p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"5 ","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort","authors":"Gillian M. Maher, Louise C. Kenny, Kate Navaratnam, Zarko Alfirevic, Darina Sheehan, Philip N. Baker, Christian Gluud, Robin Tuytten, Marius Kublickas, Boel Niklasson, Johannes J. Duvekot, Caroline B. van den Berg, Pensee Wu, Karolina Kublickiene, Fergus P. McCarthy, Ali S. Khashan","doi":"10.12688/hrbopenres.13812.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13812.1","url":null,"abstract":"<ns7:p>Background Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the assessment and refinement of innovative prototype preeclampsia risk assessment tests based on emerging biomarker technologies. Here we describe IMPROvED’s profile and invite researchers to collaborate. Methods A total of 4,038 low-risk nulliparous singleton pregnancies were recruited from maternity units in Ireland (N=1,501), United Kingdom (N=1,108), The Netherlands (N=810), and Sweden (N=619) between November 2013 to August 2017. Participants were interviewed by a research midwife at ~11 weeks (optional visit), ~15 weeks, ~20 weeks, ~34 weeks’ gestation (optional visit), and postpartum (within 72-hours following delivery). Findings to date Clinical data included information on maternal sociodemographic, medical history, and lifestyle factors collected at ~15 weeks’ gestation, and maternal measurements, collected at each study visit. Biobank samples included blood, urine, and hair collected at each study visit throughout pregnancy in all units plus umbilical cord/blood samples collected at birth in Ireland and Sweden. A total of 74.0% (N=2,922) had an uncomplicated pregnancy, 3.1% (N=122) developed preeclampsia, 3.6% (N=143) had a spontaneous preterm birth, and 10.5% (N=416) had a small for gestational age baby. We evaluated a panel of metabolite biomarkers and a panel of protein biomarkers at 15 weeks and 20 weeks’ gestation for preeclampsia risk assessment. Their translation into tests with clinical application, as conducted by commercial entities, was hampered by technical issues and changes in test requirements. Work on the panel of proteins was abandoned, while work on the use of metabolite biomarkers for preeclampsia risk assessment is ongoing. Future plans In accordance with the original goals of the IMPROvED study, the data and biobank are now available for international collaboration to conduct high quality research into the cause and prevention of adverse pregnancy outcomes.</ns7:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"31 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136348626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-designing a recruitment strategy for lung cancer screening in high-risk individuals: protocol for a mixed-methods study","authors":"Maeve Reilly, Ahmeda Ali, Prof Frank Doyle, Seamus Cotter, Laura Heavey, Prof Kate Brain, Prof Nicole Rankin, Grace Mccutchan, Prof Patrick Redmond","doi":"10.12688/hrbopenres.13793.1","DOIUrl":"https://doi.org/10.12688/hrbopenres.13793.1","url":null,"abstract":"<ns7:p>Background Lung cancer is a significant cause of cancer-related mortality globally, with early detection through screening critical to improving patient outcomes. However, recruiting high-risk individuals, particularly in deprived populations, for screening remains a considerable challenge. This study aims to co-design a targeted recruitment strategy for lung cancer screening, tailored to the specific needs and experiences of high-risk individuals, in collaboration with a Patient and Public Involvement (PPI) panel and expert stakeholders in Ireland. Methods We will employ a mixed-methods design guided by the Medical Research Council (MRC) framework for developing complex interventions. Our approach will integrate systematic review findings on screening participation interventions, evaluation of the recruitment strategy's feasibility in an Irish context, and the application of behavioural science frameworks. The target population includes individuals over 55 years, either current smokers or those who quit within the last year, who reside in highly deprived areas. Conclusion This co-designed recruitment strategy will combine evidence-based research, local context understanding, and stakeholder input to develop a solution that is both scientifically robust and tailored to the target population's needs. This patient-centred approach aims to increase the potential for successful implementation of lung cancer screening programs, thereby improving early detection and patient outcomes.</ns7:p>","PeriodicalId":73254,"journal":{"name":"HRB open research","volume":"76 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136346464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}