Exploratory research in clinical and social pharmacy最新文献

{"title":"Qualitative analysis to explore the barriers and facilitators around the implementation of automated dispensing cabinets at a large NHS Trust in England","authors":"Melanie Dalby ,&nbsp;Ali Alazab ,&nbsp;Navila Talib Chaudhry","doi":"10.1016/j.rcsop.2025.100562","DOIUrl":"10.1016/j.rcsop.2025.100562","url":null,"abstract":"<div><h3>Background</h3><div>Automated dispensing cabinets (ADCs) as a tool to store and manage medication are becoming more widely used in healthcare settings. Although there is literature surrounding their effectiveness at reducing medication error and time for nursing and pharmacy staff, there is little information on how to implement ADCs on a large scale in a busy working clinical environment. The purpose of this study was to qualitatively determine the enablers and barriers to the implementation of ADCs in a hospital setting.</div></div><div><h3>Methods</h3><div>Participants were selected through purposeful sampling and invited to attend online focus groups and interviews via Microsoft Teams. These were recorded and transcribed. Two facilitators independently reviewed the transcriptions, coded and developed themes using Nvivo.</div></div><div><h3>Results</h3><div>There were 18 participants that took part in four focus groups and three interviews. These participants were from the pharmacy department, nursing, estates and the external porter company used for medication and supply. Nine themes and 31 sub-themes were identified from the data. The nine themes were; overall thoughts, strategy of implementation, stakeholder engagement, training, workflow changes, environment, evaluation, challenges and solutions to challenges.</div></div><div><h3>Conclusion</h3><div>This study has provided new insight into the required elements for implementing a large scale piece of new technology into a hospital setting. The data complemented other studies such as the challenges with staff training and the importance of ongoing optimisation of the ADCs post implementation. Key recommendations for others looking to implement ADCs include utilising videos and written materials for training early on and including nursing staff in the core project implementation team as well introducing mock cabinets for staff to practice on.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100562"},"PeriodicalIF":1.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and facilitators to community pharmacist-provided injectable naltrexone for formerly incarcerated individuals during community reentry","authors":"Jason S. Chladek ,&nbsp;Michelle A. Chui","doi":"10.1016/j.rcsop.2025.100561","DOIUrl":"10.1016/j.rcsop.2025.100561","url":null,"abstract":"<div><h3>Introduction</h3><div>Medications for opioid use disorder (MOUD), including injectable naltrexone, are a key component in the treatment of opioid use disorder (OUD). These medications are especially important for individuals transitioning out of correctional facilities and back into their communities. Unfortunately, few formerly incarcerated individuals have access to MOUD upon reentry, incurring a 40-fold greater likelihood of overdose following release compared to the general population. In Wisconsin, community pharmacists have the authority to administer naltrexone injections. However, they have not been explored as a resource for improving access to this medication for this patient population.</div></div><div><h3>Objective</h3><div>As a first step, the goal of this study was to understand the barriers and facilitators impacting the use of community pharmacist-provided injectable naltrexone by formerly incarcerated individuals during community reentry period.</div></div><div><h3>Materials and methods</h3><div>The researcher conducted semi-structured interviews with 18 individuals representing five stakeholder groups, including four MOUD prescribers, three community pharmacists, four correctional staff, four community organization or non-profit staff, and three individuals or family members/caregivers of individuals with a history of OUD and incarceration. Deductive and inductive content analysis were used to identify barrier and facilitator categories across the five levels of the Socioecological Model.</div></div><div><h3>Results</h3><div>Overall, participants discussed factors at every level, and many barriers and facilitators confirmed findings from existing literature focused on MOUD access for formerly incarcerated individuals. Participants also identified factors more specific to community pharmacies, including 1) lack of interagency collaboration between pharmacists, prescribers, and correctional facilities and 2) lack of awareness of community pharmacist-provided injectable naltrexone services.</div></div><div><h3>Conclusions</h3><div>Future research should explore interventions to address the barriers identified in this study and improve connections between community pharmacists and formerly incarcerated individuals. This work can help ensure that these individuals are given the chance to successfully reintegrate into their communities.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100561"},"PeriodicalIF":1.8,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A descriptive report on the impact of pharmacy workflows in the operational success of hospital at home implementation at a county academic hospital system","authors":"Jason N. Levy ,&nbsp;Joshua Wollen ,&nbsp;Phuoc Anne Nguyen ,&nbsp;Catina Brimmer ,&nbsp;Rohan Dwivedi ,&nbsp;Shane Tolleson","doi":"10.1016/j.rcsop.2025.100560","DOIUrl":"10.1016/j.rcsop.2025.100560","url":null,"abstract":"<div><h3>Background</h3><div>The hospital at home (HaH) model has become more prevalent in the American healthcare system due to its ability to decrease acute care costs and readmission risk. Recent publications have provided guidance on optimizing medication management and patient safety by leveraging clinical pharmacy services. There is limited data on pharmacoeconomic impact of HaH implementation, specifically in underinsured patients.</div></div><div><h3>Objective(s)</h3><div>To describe the development of HaH-related pharmacy workflows and evaluate the operational success of the program in an underinsured patient population.</div></div><div><h3>Methods</h3><div>This report describes HaH program implementation between August 1st, 2022, and March 19th, 2024. Patients were eligible for home treatment if they met geographic, clinical, financial, and social criteria.</div></div><div><h3>Outcomes</h3><div>The primary outcome measured was the quantity and cost of medication waste for patients treated at home. Secondary outcomes included HaH medication turnaround time, healthcare resource utilization, and patient safety. All study outcomes were reported using descriptive statistics.</div></div><div><h3>Results</h3><div>Out of 450 patients screened, 3 met criteria and provided consent for HaH enrollment. The total cost of medication waste for all 3 patients was $41.15, and 21 out of 53 dispensed doses (40 %) were wasted. The mean medication verification time was 8.1 min, and the mean medication preparation time was 50.2 min.</div></div><div><h3>Conclusion</h3><div>Study data provides insight into enhancing dispensing practices while establishing the benefits pharmacists bring to the HaH care team. Future research should elaborate on other measures of operational success to identify optimal performance metrics to support expanding pharmaceutical services within the HaH care model.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100560"},"PeriodicalIF":1.8,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a community pharmacy cardiovascular practice transformation (CPT) program on blood pressure","authors":"William R. Doucette ,&nbsp;Eilan Alhersh ,&nbsp;Lindsey Ludwig ,&nbsp;Stevie Veach","doi":"10.1016/j.rcsop.2024.100559","DOIUrl":"10.1016/j.rcsop.2024.100559","url":null,"abstract":"<div><h3>Objectives</h3><div>To implement the Cardiovascular Practice Transformation (CPT) program and evaluate its impact on blood pressure, and to assess the feasibility of implementing the CPT program by identifying obstacles and facilitators.</div></div><div><h3>Methods</h3><div>Twenty-three Iowa pharmacies participated in the program, each monitoring approximately 10 hypertensive patients for 6 months. Pharmacists assessed blood pressure, medication adherence and addressed medication-related problems during patient visits. Pharmacists used a JotForm application to report patient demographics and care provided during visits. Also, blood pressure readings were collected or measured and reported. After six months, an online Qualtrics survey was sent to participating pharmacies to assess obstacles and facilitators to CPT program implementation. Descriptive statistics were calculated for the patient sample and paired <em>t</em>-tests compared baseline and final blood pressure readings. Frequencies were calculated for obstacles and facilitators.</div></div><div><h3>Results</h3><div>A total of 232 patients participated, with 138 patients having both baseline and follow-up blood pressure data. Systolic blood pressure decreased from 144.2 to 133.6 mmHg, and diastolic blood pressure decreased from 84.4 to 78.3 mmHg, with <em>p</em> &lt; 0.01 for both. Peer coaching and CPT resources were the main facilitators, while obstacles included documentation and staff time constraints.</div></div><div><h3>Conclusion</h3><div>Overall, the CPT program successfully supported pharmacies in improving blood pressure management.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100559"},"PeriodicalIF":1.8,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, perceptions, facilitators, and barriers towards asthma self-management among patients: A systematic review of the literature","authors":"Saba Alyas ,&nbsp;Rabia Hussain ,&nbsp;Bayan Faisal Ababneh ,&nbsp;Siew Chin Ong ,&nbsp;Zaheer-Ud-Din Babar","doi":"10.1016/j.rcsop.2024.100558","DOIUrl":"10.1016/j.rcsop.2024.100558","url":null,"abstract":"<div><h3>Background</h3><div>Asthma self-management is an effective approach that empowers patients with asthma to control their condition and reduce its impact on their daily lives.</div></div><div><h3>Objective</h3><div>This systematic review aims to synthesize evidence regarding the knowledge, perceptions, facilitators, and barriers related to asthma self-management among patients.</div></div><div><h3>Methods</h3><div>A systematic literature search was conducted across five databases (PubMed, Science Direct, Scopus, Web of Science, and Google Scholar) using specific key terms. Studies that reported knowledge, perceptions, facilitators and barriers towards asthma self-management were included. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed to report this review. All the data from included studies were analyzed through narrative synthesis approach.</div></div><div><h3>Results</h3><div>A total of 17 studies were included in this review. The findings indicated that most patients had inadequate knowledge of asthma self-management, particularly regarding asthma fundamentals, and inhaler techniques. Patients' cultural beliefs, and perceived social stigma influenced their self-management practices. Facilitators of asthma self-management included strong partnerships with healthcare providers, social support, access to medication, and having a written asthma action plan. Conversely, poor communication with healthcare professionals, travel, smoking, and workplace challenges were identified as barriers.</div></div><div><h3>Conclusion</h3><div>There is a pressing need for education and training programs to enhance understanding of the disease, and inhaler technique in patients with asthma. Healthcare professionals should create tailored asthma action plans according to patients' beliefs and needs. Moreover, healthcare policies should be developed to promote facilitators and address barriers, to ensure effective asthma management.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100558"},"PeriodicalIF":1.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the gap: Enhancing pharmacist-physiscian collaboration through the provision of comprehensive medication reviews in community pharmacy","authors":"Ana I. Sanchez-Molina ,&nbsp;Shalom I. Benrimoj ,&nbsp;Ramon Ferri-Garcia ,&nbsp;Fernando Martinez-Martinez ,&nbsp;Miguel Angel Gastelurrutia ,&nbsp;Noelia Amador-Fernandez ,&nbsp;Victoria Garcia-Cardenas","doi":"10.1016/j.rcsop.2024.100555","DOIUrl":"10.1016/j.rcsop.2024.100555","url":null,"abstract":"<div><h3>Background</h3><div>Collaborative practice between physicians and pharmacists is particularly important in the provision of pharmacy services, such as Comprehensive Medication Reviews (CMR), which often require a close coordination between these professionals. Understanding the level and nature of this collaboration can assist in the development of strategies to enhance integrated care.</div></div><div><h3>Objectives</h3><div>(1) To evaluate the changes in level of collaborative practice between community pharmacists and physicians in the context of a CMR service compared to usual practice, from the perspective of community pharmacists, and (2) to explore the determinants of such collaborative practice.</div></div><div><h3>Design</h3><div>This research was conducted alongside a 12-months prospective longitudinal observational study.</div></div><div><h3>Methods</h3><div>Community pharmacists providing CMR and pharmacists providing usual care (nCMR) from six provinces in Spain participated in the study. To measure the level of collaborative practice from the perspective of the community pharmacist, a previously validated tool was used. Collaborative practice was assessed at baseline, 6 months and 12 months. A multiple regression analysis was undertaken.</div></div><div><h3>Results</h3><div>323 pharmacists participated in the study. At the 12-month time point there were statistical differences between CMR and nCMR groups for all factors considered in the level of collaborative practice. Determinants which showed positive significant differences between groups included: rural location of the pharmacy, pharmacists being a pharmacy owner, and female gender of the physician. The age of the pharmacist was negatively associated with higher levels of collaborative practice.</div></div><div><h3>Conclusion</h3><div>The study provides novel evidence on the level and nature of the collaborative practice between community pharmacists and physicians.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100555"},"PeriodicalIF":1.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the knowledge, attitude and practice of healthcare professionals and healthcare professional students towards household pharmaceutical waste disposal","authors":"Sheng Yuan Hiew,&nbsp;Bee Yean Low","doi":"10.1016/j.rcsop.2024.100556","DOIUrl":"10.1016/j.rcsop.2024.100556","url":null,"abstract":"<div><h3>Background</h3><div>Active pharmaceutical residues introduced into the environment through irresponsible household disposal of unused and expired medication can damage nature and health. Through medication take-back programmes, these risks can be mitigated. However, healthcare professionals' neglect of their responsibility to ensure proper disposal practices has perpetuated subpar norms among the public.</div></div><div><h3>Objectives</h3><div>The objectives of this systematic review were to assess the knowledge, attitude, and practice of household pharmaceutical waste disposal among healthcare professionals and healthcare professional students as well as to compare their respective levels of knowledge, attitude and practice.</div></div><div><h3>Methods</h3><div>A systematic search of published articles from 2014 to 2023 in three online journal databases (Pubmed, Scopus, and Web of Science) yielded an initial pool of 10,381 records, which was narrowed down by title and abstract screening to 46 relevant publications for full-text examination and the final inclusion of 21 papers for data extraction and synthesis.</div></div><div><h3>Results</h3><div>The findings revealed deficiencies in academic curricula and medication disposal training, leading to inadequate knowledge and perceptions among healthcare professionals. Many healthcare professionals consider public education about safe medication disposal practices to be outside their job descriptions, leading to infrequent communication of medication disposal methods to their consumers and service users. Additionally, inadequate and inaccessible infrastructure further hinders proper medication disposal practices despite awareness of the consequences.</div></div><div><h3>Conclusions</h3><div>This study provides insights for policymakers and educators to address these and enhance healthcare professionals' participation in improving safe medication disposal practices. Efforts to strengthen training programmes, incorporate comprehensive education on medication disposal into curricula, and improve infrastructure for safe medication disposal are essential to effectively address the issue of household pharmaceutical waste disposal.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100556"},"PeriodicalIF":1.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-development of a community pharmacy training regarding fentanyl and xylazine test strips","authors":"Grace Marley ,&nbsp;Cheryl Viracola ,&nbsp;Ainsley Bryce ,&nbsp;Anthony Hudson ,&nbsp;Elizabeth Locklear ,&nbsp;Bayla Ostrach ,&nbsp;Delesha Carpenter","doi":"10.1016/j.rcsop.2024.100557","DOIUrl":"10.1016/j.rcsop.2024.100557","url":null,"abstract":"<div><h3>Introduction</h3><div>Fentanyl and xylazine test strips (FTS, XTS) are simple point-of-care tests that determine the presence of fentanyl or xylazine in a substance before use. Access to FTS and XTS is limited. For pharmacists who are willing to sell an FTS, there is little guidance about how to implement FTS sales and counseling as no training for community pharmacists regarding FTS and XTS exists. This article describes how a FTS and XTS training for community pharmacists was co-designed.</div></div><div><h3>Methods</h3><div>A co-design strategy was utilized that involved an advisory panel of eight members: three practicing community pharmacists, two harm reduction experts, a website developer, the director of practice advancement for the state pharmacy association, and a patient-provider communication expert. A total of six meetings occurred to develop the training over seven months from July 2023 to February 2024. The advisory panel met once a month to discuss training goals, develop training information, and revise and structure the training to ensure the acceptability and appropriateness of the training for North Carolina community pharmacists.</div></div><div><h3>Results</h3><div>The co-design strategy led to the development of a 6-module 30-min training. Module topics included information that stakeholders felt was most important to include: (1): What and Why of Test Strips, (2) Why pharmacies? (3) How to use/ “Best practices of testing” (4) Logistics (5) FAQs and (6) Resources. Panelists determined an online self-paced webinar would be most useful for pharmacists to reference when needed.</div></div><div><h3>Conclusion</h3><div>The inclusion of stakeholders, including product end-users, leads to the creation of content that is salient and feasible for pharmacists to implement, which may increase their ability to integrate a new pharmacy service (FTS and XTS sales and counseling) into their pharmacy workflow.</div></div><div><h3>Patient or public contribution</h3><div>This training was developed through a co-design strategy for community pharmacists with community pharmacist input. This training also utilized feedback from harm reduction experts who have trained people who use drugs on the best practices of testing their substances with FTS and XTS. The incorporation of their feedback was integral to the development of this training and will ensure that the training is feasible for the pharmacist to integrate into their workflow.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100557"},"PeriodicalIF":1.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging gaps in medication therapy management at community health centers: A mixed-methods study on patient perceptions and pharmacists' preparedness","authors":"Nanang Munif Yasin ,&nbsp;Fivy Kurniawati ,&nbsp;Firda Ridhayani","doi":"10.1016/j.rcsop.2024.100554","DOIUrl":"10.1016/j.rcsop.2024.100554","url":null,"abstract":"<div><h3>Background</h3><div>The primary goals of Medication Therapy Management (MTM) are to avoid pharmaceutical mistakes, facilitate accessible therapy, and encourage patients to actively participate in their health management.</div></div><div><h3>Objectives</h3><div>This study aimed to determine patients' perceptions of MTM services, evaluate the knowledge, attitudes, and practices (KAP) of Community Health Center (CHC) pharmacists regarding MTM services, and develop strategies to improve MTM services in CHCs.</div></div><div><h3>Methods</h3><div>A mixed-method approach was designed in three parts. First, a study was conducted with diabetic or hypertensive patients at CHCs around Yogyakarta to assess their perceptions of MTM elements and benefits. Second, a survey was conducted among CHC pharmacists to determine their KAP concerning MTM and the current service provided. In the third part, findings from the second stage were used to establish appropriate MTM services for CHCs through focus group discussions (FGDs) and to explore obstacles to implementation. Qualitative data were analyzed using inductive content analysis.</div></div><div><h3>Results</h3><div>Among 117 patient participants, over 60.0 % perceived positive benefits from five elements of MTM. Among 37 pharmacist participants, 19 (51.4 %) of them did not understand MTM concepts, with 14 (37.9 %) pharmacists demonstrating a low level of knowledge. Nearly all pharmacists held a positive attitude towards MTM. Time constraints were identified as barriers to MTM implementation. Based on the FGD with 24 pharmacists, three main themes and ten sub-themes were identified.</div></div><div><h3>Conclusions</h3><div>MTM services have not been fully implemented by pharmacists at CHCs. Future implementation of MTM is expected to be more adaptive to the CHCs condition, integrated with existing systems, standardized in terms of procedures and facilities.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100554"},"PeriodicalIF":1.8,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High alert medications off the radar: A systematic review","authors":"Michelle Santos Menezes,&nbsp;Fernanda Valença-Feitosa,&nbsp;Aline Santana Góes,&nbsp;Millena Rakel dos Santos,&nbsp;Laila Santana Silva,&nbsp;Sylmara Nayara Pereira dos Santos,&nbsp;Divaldo Pereira de Lyra Jr,&nbsp;Alfredo Dias de Oliveira Filho","doi":"10.1016/j.rcsop.2024.100551","DOIUrl":"10.1016/j.rcsop.2024.100551","url":null,"abstract":"<div><h3>Objective</h3><div>To identify new drugs that present an increased risk of causing significant damage to critically ill patients due to failure in the administration process.</div></div><div><h3>Method</h3><div>The systematic literature review was conducted in the PubMed, Lilacs, Scopus, Web of Science and gray literature. The year in which the study was conducted was not restricted.</div></div><div><h3>Results</h3><div>The initial search in the databases identified 1477 studies. Fifty manuscripts were selected for evaluation of the full text, at the end of which seven articles were included in this systematic review. As for the characteristic of medication errors, the highest frequency occurred in the administration and prescription phases. In all included studies, incidents with drugs that led to damage were observed. The drugs that are not included in the official lists as High Alert Medications (HAM) that presented an increased risk of causing damage due to medication errors found were: risperidone and piperacycline + tazobactan, in addition to the Infectious Agent class.</div></div><div><h3>Conclusion</h3><div>The results revealed that in fact there are drugs not listed as HAM that, when used in errors, promote greater risks of generating damage in critically ill patients. These described drugs should be considered for inclusion in future official lists of HAM.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"17 ","pages":"Article 100551"},"PeriodicalIF":1.8,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}