Exploratory research in clinical and social pharmacy最新文献

{"title":"Improved medication adherence and health literacy in parents of children with ADHD: Effects of a targeted educational program","authors":"Nafiseh Valaei Sharif ,&nbsp;Peivand Ghasemzadeh ,&nbsp;Niayesh Mohebbi ,&nbsp;Sogand Ghasemzadeh","doi":"10.1016/j.rcsop.2025.100634","DOIUrl":"10.1016/j.rcsop.2025.100634","url":null,"abstract":"<div><h3>Background</h3><div>Although medication is important for children with Attention Deficit Hyperactivity Disorder (ADHD), medication adherence is low among parents. One of the key factors affecting medication adherence and disorder management is health literacy.</div></div><div><h3>Objective</h3><div>This study aimed to assess the effectiveness of an educational program for parents of children with ADHD in improving medication adherence and health literacy.</div></div><div><h3>Methods</h3><div>An educational program was developed that covered four main topics: general disorder information, treatment, parenting based on emotional needs, and basic health information. A total of 191 parents were screened and assigned 108 eligible participants to either the intervention group (<em>n</em> = 74) or the control group (<em>n</em> = 35). The intervention group received a two-month educational program delivered via messenger application, while the control group received general counseling. Medication adherence and health literacy were measured before and after the intervention. <em>t</em>-test, ANOVA, ANCOVA, and chi-square test were used to compare group differences.</div></div><div><h3>Results</h3><div>Post-intervention, the intervention group showed significantly higher medication adherence (6.87 ± 1.36) than the control group (5.46 ± 1.45). The intervention group also demonstrated higher health literacy scores (82.34 ± 6.96) than the control group (72.15 ± 6.52). Covariance analysis revealed significant improvements in health literacy (F = 162.73, <em>p</em> &lt; 0.001, eta squared = 0.657) and medication adherence (F = 40.41, p &lt; 0.001, eta squared = 0.322) scores. A significant difference was found in medication adherence improvement based on economic status (<em>p</em> = 0.037) in the intervention group. However, no significant differences in medication adherence and health literacy were observed based on parental gender, education level, or insurance status.</div></div><div><h3>Conclusion</h3><div>The educational program showed improvement in medication adherence and health literacy among parents of children with ADHD.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100634"},"PeriodicalIF":1.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Streamlining one-dose package-handling process improves operational efficiency when dispensing drugs: A retrospective study","authors":"Takahiro Kato ,&nbsp;Miki Kato ,&nbsp;Kazuyo Nagashiba ,&nbsp;Masayuki Takeuchi ,&nbsp;Masafumi Onishi","doi":"10.1016/j.rcsop.2025.100635","DOIUrl":"10.1016/j.rcsop.2025.100635","url":null,"abstract":"<div><h3>Background</h3><div>Japanese pharmacists aim to improve efficiency and communication by simplifying work processes and developing protocols. While assistants and robots have been shown to improve drug dispensing, reports on the efficiency of pharmacies with automated dispensing systems are limited. This study explores factors affecting pharmacist efficiency in dispensing.</div></div><div><h3>Methods</h3><div>77Daily reports from our hospital pharmacy (December 1, 2020–November 30, 2021) were retrospectively analyzed. The primary outcome was the mean duration of drug dispensing. Multiple regression analyses identified factors affecting dispensing time. Strategies to address these factors were implemented, and outcomes were evaluated using data from December 1, 2021–November 30, 2022.</div></div><div><h3>Results</h3><div>Univariate analysis identified that the prescription/pharmacist ratio, number of one-dose package (ODP) prescriptions, and powdered drugs significantly influenced dispensing time. Multivariate analysis confirmed that the prescription/pharmacist ratio (<em>p</em> &lt; 0.001), ODP prescriptions (p &lt; 0.001), and powdered drugs (<em>p</em> = 0.02) were key factors. A higher number of ODP prescriptions generally increased dispensing time. After implementing a new strategy for checking ODP, mean dispensing time decreased from 20.0 ± 4.0 to 18.5 ± 3.6 min (p &lt; 0.001), and the percentage of tasks completed in under 20 min increased from 56.3 % to 73.6 % (p &lt; 0.001). Dispensing times were reduced without changing staffing levels by reallocating tasks.</div></div><div><h3>Conclusions</h3><div>Optimizing the ODP verification workflow enhances dispensing efficiency without increasing pharmacist workload, highlighting the importance of prioritizing ODP prescriptions and implementing support tools for final checks, while further multicenter studies are needed to confirm these findings across diverse settings.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100635"},"PeriodicalIF":1.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary perspective on a pharmacist-led vaccination clinic in a regional cancer care setting: A qualitative study","authors":"Kristoffer Johnstone ,&nbsp;Joyce Cooper ,&nbsp;John Smithson ,&nbsp;Beverley Glass","doi":"10.1016/j.rcsop.2025.100633","DOIUrl":"10.1016/j.rcsop.2025.100633","url":null,"abstract":"<div><h3>Background</h3><div>Immunosuppression in patients with cancer increases susceptibility to vaccine-preventable diseases, with suboptimal vaccination rates attributed to complex treatment schedules, timing of vaccination and uncertainty in relation to vaccination effectiveness. While pharmacists are routinely vaccinating patients in the community, high-risk cohorts, such as oncology patients, often lack access to dedicated vaccine services in hospital outpatient settings. Pharmacist-led vaccination clinics offer a promising solution to overcome existing barriers by integrating accessible, trusted healthcare professionals into patients' treatment location, to improve uptake through timely, co-located, and coordinated care. This study aimed to explore the perspectives of healthcare professionals regarding the implementation of a pharmacist-led vaccine clinic in an outpatient oncology unit.</div></div><div><h3>Methods</h3><div>Semi-structured interviews were conducted with pharmacists, nurses, and doctors from a single site regional referral hospital. Interviews were audio-recorded, transcribed verbatim, deductively and inductively coded and thematically analysed, with emerging themes mapped to the constructs of the Diffusion of Innovation Theory: relative advantage, complexity, compatibility, observability and trialability.</div></div><div><h3>Results</h3><div>Nineteen interviews were conducted with healthcare professionals, including seven pharmacists, six nurses and six doctors. Factors identified for successful implementation of a pharmacist-led vaccination clinic included patient-centred models, improved convenience and reduced complexity for patients, and compatibility with pharmacists' existing knowledge and role in outpatient units. Barriers were found to be work overload for pharmacists, reduced interaction with general practitioners, and lack of understanding of pharmacists' vaccination training.</div></div><div><h3>Conclusion</h3><div>Healthcare professionals expressed strong support for a pharmacist-led vaccine clinic in an outpatient oncology unit, recognising the potential to improve vaccination rates. Future research should however focus on assessing patient acceptance of such a service and the impact of such a clinic on vaccination rates.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100633"},"PeriodicalIF":1.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing six sigma management to shorten the time of taking medicine from intelligent medicine cabinet in inpatient ward","authors":"Dan Zhao,&nbsp;Jie Wang,&nbsp;Mengting Sun,&nbsp;Tao Wu,&nbsp;Yingxin Peng","doi":"10.1016/j.rcsop.2025.100631","DOIUrl":"10.1016/j.rcsop.2025.100631","url":null,"abstract":"<div><h3>Background</h3><div>Medication errors and delays in drug dispensing are persistent challenges in traditional pharmacy systems. Automated Dispensing Cabinets (ADCs) were introduced at the study hospital in July 2022 to improve medication safety and efficiency. However, the initial implementation phase revealed several issues, including prolonged medication retrieval times, suboptimal cabinet layout, system interface limitations, and inconsistent user operations. These challenges highlighted the need for further system optimization using a structured improvement approach.</div></div><div><h3>Objective</h3><div>This study aims to implement an inpatient pharmacy management system based on Six Sigma methodology and compare its effectiveness with TPS in terms of medication convenience and error reduction.</div></div><div><h3>Methods</h3><div>Starting in July 2022, an intelligent pharmacy management model was implemented in inpatient wards, centered around ADCs and guided by the Six Sigma methodology. Comprehensive improvements were made to address issues such as baseline medication management inefficiencies and delays in retrieving medications for temporary orders. The study compared various metrics, including the time required for retrieving medications for temporary orders, medication administration time, medication error rates before after one month of implementing the intelligent system and nurses' satisfaction with the intelligent system.</div></div><div><h3>Results</h3><div>Compared with the pre-implementation phase, the intelligent system significantly reduced the time required for nurses to retrieve medications and execute orders (<em>P</em> &lt; 0.05). The rates of medication retrieval and administration errors also decreased (P &lt; 0.05). A majority of nurses (86.96 %) reported that the intelligent system improved work efficiency, 92.40 % found it easier to retrieve medications during emergencies, and 97.82 % expressed high satisfaction with the system.</div></div><div><h3>Conclusion</h3><div>The application of an intelligent inpatient pharmacy management system based on the Six Sigma methodology effectively reduced the time nurses needed to retrieve medications, enhanced overall nurse satisfaction, lowered error rates caused by human factors.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100631"},"PeriodicalIF":1.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of patient perception and administration technique of vaginal tablets at a tertiary care women's hospital","authors":"Nirmal Raj Marasine ,&nbsp;Garima Kunwar ,&nbsp;Manisha Chaudhary ,&nbsp;Anjana Adhikari ,&nbsp;Sabina Sankhi","doi":"10.1016/j.rcsop.2025.100632","DOIUrl":"10.1016/j.rcsop.2025.100632","url":null,"abstract":"<div><h3>Background</h3><div>Vaginal tablets offer an effective and patient-friendly route for both localized and systemic therapies, bypassing hepatic first-pass metabolism and minimizing gastrointestinal side effects. However, in low-resource settings like Nepal, their optimal use is often hindered by patient's perception and administration techniques.</div></div><div><h3>Objective</h3><div>This study aimed to assess patient perception and administration technique of vaginal tablets at a tertiary women's hospital in Nepal.</div></div><div><h3>Methods</h3><div>A hospital-based cross-sectional study was conducted from February to July 2024 among 117 women of reproductive age visiting a tertiary care women's hospital in Kathmandu. Data were collected through face-to-face interviews using a validated 8-item perception questionnaire and an 8-item administration technique checklist. Bivariate analysis using Pearson's chi-square test and binary logistic regression were performed to identify factors associated with patients' perceptions and administration techniques.</div></div><div><h3>Results</h3><div>More than half (56.4 %) of the patient's demonstrated adequate administration techniques (scores ≥6), yet a striking 76.1 % exhibited suboptimal perceptions towards vaginal tablet use. Factors such as being unmarried, having lower educational attainment (illiterate or school level education), being unemployed or a housemaker, residing in rural areas, and lacking prior experience were significantly associated with poorer perceptions. Notably, younger age, prior use and counseling by pharmacists were positively linked to better administration techniques.</div></div><div><h3>Conclusion</h3><div>Despite adequate administration practices among most women, suboptimal perceptions persist, influenced by demographic and experiential factors. Tailored, provider-led educational interventions focusing on counseling and user-friendly instructions are essential to enhance patient understanding, comfort, and adherence, thereby improving therapeutic outcomes and empowering women in their reproductive health decisions.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100632"},"PeriodicalIF":1.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144588038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not so great expectations: The role of price and name information in the nocebo effect","authors":"Kiarne Humphreys ,&nbsp;Michelle Lin ,&nbsp;Kirsten Barnes ,&nbsp;Yasmin Hasan ,&nbsp;Ashwin Vignaraja ,&nbsp;Kritika Sarna ,&nbsp;Andrew L. Geers ,&nbsp;Kate Faasse","doi":"10.1016/j.rcsop.2025.100630","DOIUrl":"10.1016/j.rcsop.2025.100630","url":null,"abstract":"<div><h3>Background</h3><div>The perception of taking a generic medication can result in reduced efficacy and increased side effects, despite equivalence to brand name medications under double blind conditions. It may be that cues typically associated with generics, including lower price and more complex name, exacerbate negative expectations and cause nocebo effects.</div></div><div><h3>Methods</h3><div>Healthy participants (<em>N</em> = 196) were randomised to receive sham-oxytocin nasal spray associated with either a generic (complex name, low price; <em>n</em> = 66) or brand (simple name, high price; <em>n</em> = 68) cue, or to no treatment control (<em>n</em> = 62). Participants were informed that oxytocin could enhance trust and cooperation, but might cause side effects of headache, nausea, vomiting, rapid heartbeat, feeling faint or light-headed, and skin itching or rash. Treatment-related side effects were assessed at baseline, and after 3 days of sham-oxytocin use.</div></div><div><h3>Results</h3><div>Nocebo effects were observed across sham-treated participants relative to control (<em>p</em> = .015; <em>d</em> = 0.28). Association with a generic relative to branded cue significantly enhanced nocebo effects (<em>p</em> = .042; <em>d</em> = 0.36). Negative expectations mediated the observed nocebo and branding effects.</div></div><div><h3>Conclusions</h3><div>Cues associated with generic medications can exacerbate nocebo effects and these findings may explain clinical observations of increased side effects from generic medications. Results have important implications for medical care, and interventions to mitigate nocebo effects from generic medications are needed.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100630"},"PeriodicalIF":1.8,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported treatment burden: A comparison between vitamin K and non-vitamin K oral anticoagulants","authors":"Miroslav Mihajlovic ,&nbsp;Nevena Zec ,&nbsp;Jelena Simic ,&nbsp;Aleksandar Mihajlovic ,&nbsp;Milan Marinkovic ,&nbsp;Nebojsa Mujovic ,&nbsp;Tatjana Potpara","doi":"10.1016/j.rcsop.2025.100628","DOIUrl":"10.1016/j.rcsop.2025.100628","url":null,"abstract":"<div><h3>Introduction</h3><div>Treatment burden (TBN) refers to the impact of patients' healthcare-related workload on their functioning and well-being. A high TBN has been associated with lower adherence to treatment and increased risk of major adverse events, and patients considered a TBN score of ≥59 points as unacceptably high. In the present analysis, we explored differences in TBN, the prevalence of unacceptably high TBN score and discern the contributory factors associated with TBN among patients receiving vitamin K oral anticoagulants (VKA) or non-vitamin K oral anticoagulants (NOAC).</div></div><div><h3>Methods</h3><div>In a single-centre cross-sectional study from April to June 2019, consecutive patients receiving medical care at the Cardiology Clinic of University hospital were invited to fulfil the TBN Questionnaire encompassing 17 questions assessing TBN.</div></div><div><h3>Results</h3><div>Of 514 study patients, 320 (62.3 %) were taking oral anticoagulant therapy (OAC) and were included in the present analysis. Of those, 206 patients (64.4 %) were prescribed a VKA. The mean TBN score was significantly higher in VKA versus NOAC patients (48.8 ± 26.5 vs. 41.8 ± 19.7, <em>P</em> = 0.014). Patients taking VKA reported a TBN of ≥59 points significantly more often than those taking NOAC (30.1 % vs 18.4 %, <em>P</em> = 0.024). The VKA patients reported significantly higher TBN score values for questions related to self-monitoring, including INR monitoring (3.85 ± 3.32 vs. 1.62 ± 1.38, <em>P</em> &lt; 0.001) and diet restrictions (3.98 ± 3.43 vs. 2.48 ± 2.49, P &lt; 0.001) compared with NOAC patients.</div></div><div><h3>Conclusion</h3><div>In the present study, VKA patients reported significantly higher TBN and more frequently unacceptably high TBN compared to NOAC, primarily due to numerous VKA-food interactions and the need for regular INR monitoring. Our findings suggest that the prescription of NOAC could reduce the TBN, which could translate to improved patient outcomes.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100628"},"PeriodicalIF":1.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative exploration of community pharmacist views on providing a mental health and well-being intervention for long-term condition patients","authors":"Patrick Cabasag ,&nbsp;Kebede Beyene ,&nbsp;Frederick Sundram ,&nbsp;Amy Hai Yan Chan ,&nbsp;Holly Wilson ,&nbsp;Jeff Harrison","doi":"10.1016/j.rcsop.2025.100629","DOIUrl":"10.1016/j.rcsop.2025.100629","url":null,"abstract":"<div><h3>Background</h3><div>Subthreshold depression and anxiety are common, affecting up to 24 % of people over their lifetime and are often associated with long-term conditions. Community pharmacists, who often have an established relationship with people who have long-term conditions, are well placed to identify and address subthreshold depression and anxiety and reduce the risk of progression to clinical mental health disorders.</div></div><div><h3>Methods</h3><div>Semi-structured individual qualitative interviews were conducted with community pharmacists to explore their perspectives on a pharmacy service for long-term condition patients with subthreshold depression and anxiety. Interviews were audio recorded, transcribed in intelligent verbatim and analysed using a General Inductive Approach.</div></div><div><h3>Results</h3><div>Eleven purposively selected community pharmacists from diverse backgrounds were interviewed. Four main themes were identified, each with several subthemes. These related to existing support mechanisms for delivering long-term condition and mental health services in community pharmacies, pharmacists' perceptions and attitudes toward service delivery, barriers and facilitators to service implementation, and the design and implementation of a service.</div></div><div><h3>Conclusions</h3><div>This is the first study to explore community pharmacists' perspectives on a pharmacy intervention for long-term condition patients with subthreshold depression and anxiety. Overall, community pharmacists expressed positive attitudes toward delivering an intervention for people with long-term conditions and subthreshold depression and anxiety. Future work would involve taking a co-design approach to developing and evaluating such an intervention.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100629"},"PeriodicalIF":1.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building primary care providers' confidence in deprescribing opioids and benzodiazepines in older adults","authors":"Stefanie P. Ferreri ,&nbsp;Lori T. Armistead ,&nbsp;Ben Urick ,&nbsp;Tamera D. Hughes ,&nbsp;Anne-Therese Hunt ,&nbsp;J. Marvin McBride ,&nbsp;Joshua Niznik ,&nbsp;Ellen Roberts ,&nbsp;Kimberly A. Sanders ,&nbsp;Jan Busby-Whitehead","doi":"10.1016/j.rcsop.2025.100627","DOIUrl":"10.1016/j.rcsop.2025.100627","url":null,"abstract":"<div><h3>Background</h3><div>Opioids and benzodiazepines (BZDs) are among the most prescribed medications that contribute to falls in older adults; however, little guidance exists on their safe prescribing and deprescribing. Although some resources are available to assist providers with opioid and BZD deprescribing, many report lack of confidence as a barrier. The objective of this study was to assess PCPs' confidence in their ability to deprescribe opioids and BZDs before and after an intervention.</div></div><div><h3>Methods</h3><div>We modified a validated deprescribing self-efficacy survey to assess primary care provider (PCP) confidence in deprescribing opioids and BZDs in older adults before and after a consultant pharmacist educational intervention. The survey consisted of 35 questions divided into three sections: deprescribing opioids (10 questions), deprescribing BZDs (10 questions), and deprescribing under potentially impeding circumstances [UPIC] (15 questions). The survey was sent to 88 PCPs using a modified Dillman method. We evaluated providers' confidence on a 100-point scale pre- and post-intervention, comparing the difference-in- differences (DID) in scores between the intervention and control groups.</div></div><div><h3>Results</h3><div>A total of 41 PCPs (46.6 %) completed the survey both pre-and post-intervention. The intervention group (<em>n</em> = 21) showed an improvement in their knowledge and self-efficacy skills by an average of 19.7 out of 100 points, while the control group (<em>n</em> = 20) improved by an average of 5.2 points. The DID in self-efficacy improvement between the two groups was +14.5 points (<em>p</em> = 0.003) overall. For each of the opioid-, BZD-, and UPIC-specific scores, the intervention group had a statistically significant DID compared to the control group (+15.8, <em>p</em> = 0.004; +14.2, <em>p</em> = 0.017; +13.9, <em>p</em> = 0.016, respectively).</div></div><div><h3>Conclusion</h3><div>This consultant pharmacist educational intervention improved PCPs' confidence in deprescribing opioids and BZDs in older adults.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100627"},"PeriodicalIF":1.8,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of U.S. pharmacists in deprescribing: Recommendations based on a systematic literature review of qualitative studies","authors":"Alina Cernasev ,&nbsp;Devin Scott ,&nbsp;Becka Eckert ,&nbsp;Hilary Jasmin ,&nbsp;David R. Axon","doi":"10.1016/j.rcsop.2025.100625","DOIUrl":"10.1016/j.rcsop.2025.100625","url":null,"abstract":"<div><h3>Purpose</h3><div>Deprescribing is increasingly investigated through a qualitative lens, yet no evidence synthesis of the extant qualitative deprescribing literature exists. This study aimed to identify and synthesize relevant qualitative data about the role of the pharmacist or pharmacy profession in deprescribing in the United States.</div></div><div><h3>Methods</h3><div>A systematic literature review was conducted in July 2024 in MEDLINE (PubMed), Scopus (Elsevier), and Embase (Elsevier). The primary search concepts included terms around pill burden, cessation and de-prescription, as well as a search string to narrow results to qualitative reports. From 4410 unique records after deduplication, 46 abstracts were included for full text review.</div></div><div><h3>Results</h3><div>After full text review, 11 records were deemed suitable for inclusion in this review. Three used interviews, five used focus groups, and three used both. Three studies used the theory of planned behavior, two studies used the capability, opportunity, and motivation behavior model, one used the chronic care model, one used the interprofessional shared decision-making model, one used grounded theory, and three did not use a framework. Studies were conducted in New York (<em>n</em> = 3), Arizona, Maine, and Tennessee (<em>n</em> = 3), California (<em>n</em> = 1), Iowa (<em>n</em> = 1), Massachusetts (<em>n</em> = 1), North Carolina (<em>n</em> = 1), and Rhode Island (<em>n</em> = 1). Key themes identified across the studies included enablers, obstacles, process of deprescribing, and deprescribing in pharmacy education.</div></div><div><h3>Conclusions</h3><div>Deprescribing is a complex process that involves the entire healthcare team, including pharmacists who have unique expertise to support the team through education and information about medication and disease states.</div></div>","PeriodicalId":73003,"journal":{"name":"Exploratory research in clinical and social pharmacy","volume":"19 ","pages":"Article 100625"},"PeriodicalIF":1.8,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}