Environmental toxicology and pharmacology最新文献

Constructing an adverse outcome pathway framework for the impact of maternal exposure to PM2.5 on liver development and injury in offspring 构建母体暴露于 PM2.5 对后代肝脏发育和损伤影响的不良后果路径框架。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-11-01 DOI: 10.1016/j.etap.2024.104585

Kexin Zhang , Li Tian , Qinglin Sun , Jianong Lv , Ruiyang Ding , Yang Yu , Yang Li , Junchao Duan

{"title":"Constructing an adverse outcome pathway framework for the impact of maternal exposure to PM2.5 on liver development and injury in offspring","authors":"Kexin Zhang , Li Tian , Qinglin Sun , Jianong Lv , Ruiyang Ding , Yang Yu , Yang Li , Junchao Duan","doi":"10.1016/j.etap.2024.104585","DOIUrl":"10.1016/j.etap.2024.104585","url":null,"abstract":"<div><div>Ambient fine particulate matter (PM<sub>2.5</sub>) is a significant contributor to air pollution. PM<sub>2.5</sub> exposure poses a substantial hazard to public health. In recent years, the adverse effects of maternal PM<sub>2.5</sub> exposure on fetal health have gradually gained public attention. As the largest organ in the body, the liver has many metabolic and secretory functions. Liver development, as well as factors that interfere with its growth and function, are of concern. This review utilized the adverse outcome pathway (AOP) framework as the analytical approach to demonstrate the link between maternal PM<sub>2.5</sub> exposure and potential neonatal liver injury from the molecular to the population level. The excessive generation of reactive oxygen species (ROS), subsequent endoplasmic reticulum (ER) stress, and oxidative stress were regarded as the essential components in this framework, as they could trigger adverse developmental outcomes in the offspring through DNA damage, autophagy dysfunction, mitochondrial injury, and other pathways. To the best of our knowledge, this is the first article based on an AOP framework that elaborates on the influence of maternal exposure to PM<sub>2.5</sub> on liver injury occurrence and adverse effects on liver development in offspring. Therefore, this review offered mechanistic insights into the developmental toxicity of PM<sub>2.5</sub> in the liver, which provided a valuable basis for future studies and prevention strategies.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microplastic contamination in the aquaculture icon Oreochromis mossambicus: Prevalence, characteristics, and comprehensive overview 水产养殖图标 Oreochromis mossambicus 中的微塑料污染：普遍性、特征和综合概述。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-31 DOI: 10.1016/j.etap.2024.104584

Pradeep Kumkar , Chandani R. Verma , Sachin M. Gosavi , Martin Lexa , Sanjay S. Kharat , Radek Rinn , Lukáš Kalous

{"title":"Microplastic contamination in the aquaculture icon Oreochromis mossambicus: Prevalence, characteristics, and comprehensive overview","authors":"Pradeep Kumkar , Chandani R. Verma , Sachin M. Gosavi , Martin Lexa , Sanjay S. Kharat , Radek Rinn , Lukáš Kalous","doi":"10.1016/j.etap.2024.104584","DOIUrl":"10.1016/j.etap.2024.104584","url":null,"abstract":"<div><div>The global production of plastics has surged to 368 million tonnes annually, leading to significant plastic waste accumulation, projected to reach 12,000 Mt by 2050, impacting aquatic ecosystems. Fish, crucial for their protein and nutrients, are particularly vulnerable to microplastic (MP) ingestion. As a major aquaculture producer and fish consumer, India faces rising plastic pollution in freshwater, which disrupts fish health and growth, posing a significant threat to the sustainability and productivity of aquaculture systems and potential health risks. This study focuses on Mozambique tilapia (<em>Oreochromis mossambicus</em>), valued for its widespread aquaculture use, rapid growth, and nutritional benefits. Our research reveals significant MP contamination (69.23 %) in Mozambique tilapia, with over 80 % from the Ulhas River and 60 % from the Bhima River contaminated and females showing higher susceptibility. These findings emphasise the need for further research on MP impacts on human health and the development of mitigation strategies.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of chronic arsenic exposure with cellular immune profile in MINIMat adolescents: A birth cohort in Bangladesh 慢性砷暴露与 MINIMat 青少年细胞免疫特征的关系：孟加拉国出生队列

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-30 DOI: 10.1016/j.etap.2024.104583

Farjana Haque , Evana Akhtar , Bikash Chandra Chanda , Anjuman Ara , Md.Ahsanul Haq , Protim Sarker , Maria Kippler , Yukiko Wagatsuma , Ondine S. von Ehrenstein , Rubhana Raqib

{"title":"Association of chronic arsenic exposure with cellular immune profile in MINIMat adolescents: A birth cohort in Bangladesh","authors":"Farjana Haque , Evana Akhtar , Bikash Chandra Chanda , Anjuman Ara , Md.Ahsanul Haq , Protim Sarker , Maria Kippler , Yukiko Wagatsuma , Ondine S. von Ehrenstein , Rubhana Raqib","doi":"10.1016/j.etap.2024.104583","DOIUrl":"10.1016/j.etap.2024.104583","url":null,"abstract":"<div><div>Chronic arsenic exposure is known to affect the immune system. We aimed to evaluate the association between arsenic exposure and immune cell profile in 15 years old adolescents (n=389) in rural Bangladesh, with chronic exposure to groundwater arsenic. Single blood and urine were collected. Urinary arsenic (U-As) concentration was measured using atomic absorption spectrometry. Peripheral blood mononuclear cells (PBMC) were analyzed by flow cytometry. Non-linear association was found between U-As (median, 24.9 µg/L) and immune cells with a cut-off at U-As 20 µg/L. U-As (<20 µg/L) were significantly associated with increases in CD8<sup>+</sup>T (21 %), na<sup>ï</sup>ve CD8<sup>+</sup>T (42 %) and early B cells (40 %), and classical monocytes (55 %), but reduction in CD3<sup>+</sup>T cells (37<sup>%</sup>) and intermediate-monocytes (56 %). U-As (>20 µg/L) were associated with a 3 % reduction in memory B cells. Arsenic exposure was associated with altered immune cell profile in adolescents likely rendering them vulnerable to adverse health effects in later life.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regeneration of zebrafish retina following toxic injury 斑马鱼视网膜毒性损伤后的再生。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-29 DOI: 10.1016/j.etap.2024.104582

Alessandra La Pietra, Anna Rita Bianchi, Teresa Capriello, Teresa Mobilio, Annamaria Guagliardi, Anna De Maio, Ida Ferrandino

{"title":"Regeneration of zebrafish retina following toxic injury","authors":"Alessandra La Pietra, Anna Rita Bianchi, Teresa Capriello, Teresa Mobilio, Annamaria Guagliardi, Anna De Maio, Ida Ferrandino","doi":"10.1016/j.etap.2024.104582","DOIUrl":"10.1016/j.etap.2024.104582","url":null,"abstract":"<div><div>The structure of the zebrafish retina appears to be very similar to that of mammals, that is why it is used as a model for studying the eye. Indeed, the zebrafish retina can regenerate itself through mechanisms of Müller cell reprogramming. In this research, adult zebrafish were exposed to aluminum to cause damage in the retina and thus evaluate the regenerative capacity of the damaged tissue. Histological and histochemical analyses assessed the retinal structure and the neurodegenerative process, respectively. An expression analysis of PARPs was carried out to verify whether a potential oxidative DNA damage happens. In addition, some genes involved in the regeneration process (<em>pax6a</em>, <em>pax2a</em>, <em>ngn1</em>, and <em>notch1a</em>) were analyzed. The data confirmed the toxicity of aluminum which caused retinal neurodegeneration, but also highlighted the ability of zebrafish to regenerate the retinal structure, repairing the damage and confirming its use as a good model for translational studies.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the impact of gadolinium contamination on the marine bivalve Donax trunculus: Implications for environmental health 评估钆污染对海洋双壳类动物 Donax trunculus 的影响：对环境健康的影响。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-28 DOI: 10.1016/j.etap.2024.104580

Silvia Secco , Marta Cunha , Giovanni Libralato , Marco Trifuoggi , Antonella Giarra , Amadeu M.V.M. Soares , Rosa Freitas , Massimiliano Scalici

{"title":"Evaluating the impact of gadolinium contamination on the marine bivalve Donax trunculus: Implications for environmental health","authors":"Silvia Secco , Marta Cunha , Giovanni Libralato , Marco Trifuoggi , Antonella Giarra , Amadeu M.V.M. Soares , Rosa Freitas , Massimiliano Scalici","doi":"10.1016/j.etap.2024.104580","DOIUrl":"10.1016/j.etap.2024.104580","url":null,"abstract":"<div><div>Gadolinium (Gd), commonly used in contrast agents for medical imaging, has been detected in hospital wastewater and aquatic environments, raising environmental concerns. This study examined the accumulation and cellular impacts of Gd in the clam species <em>Donax trunculus</em>, commonly used as bioindicator of contamination. Gadolinium accumulation in clams increased with exposure and over time. Biological responses varied with Gd levels: low concentrations (10 and 50 µg/L) led to low metabolic activity and glycogen content, but high antioxidant activities and lipid peroxidation levels (LPO); high concentrations (250 and 500 µg/L) resulted in increased metabolic activity, while antioxidant enzyme activity was inhibited and LPO levels were the lowest. Metabolic activity decreased after two weeks, suggesting limited long-term metabolic resilience. The study underscores <em>D. trunculus</em> as an effective early warning species for Gd pollution and highlights the ecological risks of rising Gd levels, emphasizing the need for environmental monitoring and regulation.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of volatile organic compound exposure and metabolic syndrome 挥发性有机化合物暴露与代谢综合征的关系。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-24 DOI: 10.1016/j.etap.2024.104581

Hee Byung Koh, Jae Ho Chung, Sung Jin Moon

引用次数: 0

Microplastic ingestion and co-exposure to Nosema ceranae and flupyradifurone reduce the survival of honey bees (Apis mellifera L.) 摄入微塑料以及同时接触陶瓷鼻疽病毒和氟吡拉呋喃酮会降低蜜蜂（Apis mellifera L.）的存活率

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-01 DOI: 10.1016/j.etap.2024.104571

Rossella Tiritelli , Laura Zavatta , Rafaela Tadei , Elaine Cristina Mathias da Silva , Fabio Sgolastra , Giovanni Cilia

{"title":"Microplastic ingestion and co-exposure to Nosema ceranae and flupyradifurone reduce the survival of honey bees (Apis mellifera L.)","authors":"Rossella Tiritelli , Laura Zavatta , Rafaela Tadei , Elaine Cristina Mathias da Silva , Fabio Sgolastra , Giovanni Cilia","doi":"10.1016/j.etap.2024.104571","DOIUrl":"10.1016/j.etap.2024.104571","url":null,"abstract":"<div><div>Bees are exposed to several threats, including pathogens (i.e. <em>Nosema ceranae</em>), pesticides and environmental contaminants. The new insecticide flupyradifurone, and the microplastics in the environment, have raised significant concerns on bee health. This study evaluated the simultaneous effects of microplastics, flupyradifurone, and <em>N. ceranae</em> on honey bee health, focusing on survival rates, <em>N. ceranae</em> replication, daily food consumption, and bee midgut histological alterations. Results showed a significant decrease in bee longevity across all treatments compared to the control, with the combination of flupyradifurone, microplastics, and <em>N. ceranae</em> having the most severe impact. Microplastics and flupyradifurone exposure also increased <em>N. ceranae</em> proliferation, especially in bees subjected to both stressors. Histological analysis revealed reduced regenerative cell nests in the midgut and changes in the nuclear matrix, indicating stress responses. Overall, the simultaneous presence of both biotic and abiotic stressors in nature can synergistically interact, leading to harmful effects on bees.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioaccumulation, transformation and toxicity of imidacloprid and dinotefuran in Eisenia fetida under single and binary exposure scenarios 在单一和二元暴露情景下，吡虫啉和克百威在胎生鳗体内的生物累积、转化和毒性。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-01 DOI: 10.1016/j.etap.2024.104570

Haiyun Zhang , Meng Zhang , Hanlin Zhang , Xiaofang Shen , Weiguang Lv , Xilong Wang , Juanqin Zhang , Xiaoying Guo

{"title":"Bioaccumulation, transformation and toxicity of imidacloprid and dinotefuran in Eisenia fetida under single and binary exposure scenarios","authors":"Haiyun Zhang , Meng Zhang , Hanlin Zhang , Xiaofang Shen , Weiguang Lv , Xilong Wang , Juanqin Zhang , Xiaoying Guo","doi":"10.1016/j.etap.2024.104570","DOIUrl":"10.1016/j.etap.2024.104570","url":null,"abstract":"<div><div>Earthworms (<em>Eisenia fetida</em>) were exposed to individual and binary mixture of imidacloprid (IMI) and dinotefuran (DIN) at 0.05 and 0.5 mg/kg for 28 days to investigate their bioaccumulation, transformation and toxicity. IMI was more easily absorbed by earthworms than DIN, and worms didn’t accumulate or generate toxic metabolites. The obvious accumulation of neonicotinoids during later period caused significant neural dysfunction, especially when exposed to high-concentration IMI. Meanwhile, oxidative stress indicated by decreased SOD/CAT activity (33.2 %-68.1 %) and increased MDA (38.4 %-55.0 %) was induced by binary exposure with high-concentration IMI. By contrast, coelomocytes responded earlier and more strongly than oxidative responses. Coelomocytes’ viability and mitochondrial membrane potential were inhibited (23.6 %-91.7 %) mainly by IMI and binary exposure. Coelomocytes’ lactate dehydrogenase activity exerted a fluctuating pattern, suggesting irregular disturbance on cellular functions. This study highlights the role of coelomocytes and the need to consider binary/multiple scenarios and transformation of neonicotinoids in their risk assessment to earthworms.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Bis (methyl glycol) phthalate on endoplasmic reticulum stress in endothelial cells 邻苯二甲酸二（甲基乙二醇）酯对内皮细胞内质网应激的影响

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-10-01 DOI: 10.1016/j.etap.2024.104569

Verma Nishitha-Hiresha , Raghavan Varsha , S. Srinidhi , Ravichandran Jayasuriya , Kannan Harithpriya , Paromita Chakraborty , Kunka Mohanram Ramkumar

{"title":"Effect of Bis (methyl glycol) phthalate on endoplasmic reticulum stress in endothelial cells","authors":"Verma Nishitha-Hiresha , Raghavan Varsha , S. Srinidhi , Ravichandran Jayasuriya , Kannan Harithpriya , Paromita Chakraborty , Kunka Mohanram Ramkumar","doi":"10.1016/j.etap.2024.104569","DOIUrl":"10.1016/j.etap.2024.104569","url":null,"abstract":"<div><div>Phthalate-based polymeric plasticizers are widely used for their durability, transparency, and odorless nature, resulting in human exposure through inhalation, ingestion, or contaminated water. Epidemiological studies have identified bis-phthalate as a potential cardiovascular disease risk factor, though its mechanisms remain unclear. This study investigates the effects of bis-phthalate on endothelial dysfunction (ED), an early event in cardiovascular complications, with a focus on Endoplasmic Reticulum (ER) stress pathways. We observed dose- and time-dependent cytotoxicity in endothelial cells exposed to bis-phthalate, accompanied by elevated expression of ER stress markers (GRP78, IRE-1α, CHOP) and oxidative stress markers (TXNIP, P22phox), as measured by qPCR. Reactive oxygen species (ROS) levels also increased dose-dependently, as determined by H2DCFDA using flow cytometry. These findings suggest that bis-phthalate exposure induces both oxidative and ER stress, leading to the development of ED, providing insights into its potential role in cardiovascular disease progression.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcitriol/vitamin D receptor system alleviates PM2.5-induced human bronchial epithelial damage through upregulating mitochondrial bioenergetics in association with regulation of HIF-1α/PGC-1α signaling 骨化三醇/维生素D受体系统通过上调线粒体生物能与调节HIF-1α/PGC-1α信号传导，减轻PM2.5诱导的人类支气管上皮损伤。

IF 4.2 3区环境科学与生态学

Environmental toxicology and pharmacology Pub Date : 2024-09-21 DOI: 10.1016/j.etap.2024.104568

Anyamanee Chatsirisupachai , Phetthinee Muanjumpon , Saowanee Jeayeng , Tasanee Onkoksong , Mutita Pluempreecha , Tanyapohn Soingam , Uraiwan Panich

{"title":"Calcitriol/vitamin D receptor system alleviates PM2.5-induced human bronchial epithelial damage through upregulating mitochondrial bioenergetics in association with regulation of HIF-1α/PGC-1α signaling","authors":"Anyamanee Chatsirisupachai , Phetthinee Muanjumpon , Saowanee Jeayeng , Tasanee Onkoksong , Mutita Pluempreecha , Tanyapohn Soingam , Uraiwan Panich","doi":"10.1016/j.etap.2024.104568","DOIUrl":"10.1016/j.etap.2024.104568","url":null,"abstract":"<div><div>PM2.5 exposure causes lung injury by triggering oxidative stress, mitochondrial dysfunction, and modulating HIF-1α signaling. Calcitriol activates VDR, which regulates cellular homeostasis. This study evaluated the protective role of the calcitriol/VDR system in PM2.5-induced damage to BEAS-2B bronchial epithelial cells by reducing oxidative stress, upregulating mitochondrial bioenergetics, and downregulating HIF-1α. We found that the calcitriol/VDR system decreased ROS formation and restored mitochondrial bioenergetics in PM2.5-treated cells. This improvement correlated with reduced HIF-1α nuclear translocation and increased PGC-1α protein and mitochondrial gene expressions. This study is the first to suggest that targeting the calcitriol/VDR system could be a promising pharmacological strategy for mitigating PM2.5-induced lung epithelial damage by promoting mitochondrial bioenergetics and regulating PGC-1α and HIF-1α signaling.</div></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1382668924002084/pdfft?md5=11259cbbbe67e7a54d2037d80831811a&pid=1-s2.0-S1382668924002084-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0