APL Photonics最新文献

{"title":"Impact of polarization pulling on optimal spectrometer design for stimulated Brillouin scattering microscopy.","authors":"Jake R Rosvold, Joseph B Murray, Giulia Zanini, Brandon Redding, Giuliano Scarcelli","doi":"10.1063/5.0225074","DOIUrl":"10.1063/5.0225074","url":null,"abstract":"<p><p>Brillouin spectroscopy has become an important tool for mapping the mechanical properties of biological samples. Recently, stimulated Brillouin scattering (<i>SBS</i>) measurements have emerged in this field as a promising technology for lower noise and higher speed measurements. However, further improvements are fundamentally limited by constraints on the optical power level that can be used in biological samples, which effectively caps the gain and signal-to-noise ratio (<i>SNR</i>) of <i>SBS</i> biological measurements. This limitation is compounded by practical limits on the optical probe power due to detector saturation thresholds. As a result, <i>SBS</i>-based measurements in biological samples have provided minimal improvements (in noise and imaging speed) compared with spontaneous Brillouin microscopy, despite the potential advantages of the nonlinear scattering process. Here, we consider how a <i>SBS</i> spectrometer can circumvent this fundamental trade-off in the low-gain regime by leveraging the polarization dependence of the <i>SBS</i> interaction to effectively filter the signal from the background light via the polarization pulling effect. We present an analytic model of the polarization pulling detection scheme and describe the trade-space unique to Brillouin microscopy applications. We show that an optimized receiver design could provide >25× improvement in <i>SNR</i> compared to a standard <i>SBS</i> receiver in most typical experimental conditions. We then experimentally validate this model using optical fiber as a simplified test bed. With our experimental parameters, we find that the polarization pulling scheme provides 100× higher <i>SNR</i> than a standard <i>SBS</i> receiver, enabling 100× faster measurements in the low-gain regime. Finally, we discuss the potential for this proposed spectrometer design to benefit low-gain spectroscopy applications such as Brillouin microscopy by enabling pixel dwell times as short as 10 <i>μ</i>s.</p>","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"9 10","pages":"100807"},"PeriodicalIF":5.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in optical biosensing techniques: From fundamentals to future prospects","authors":"Baljinder Kaur, Santosh Kumar, Jan Nedoma, Radek Martinek, Carlos Marques","doi":"10.1063/5.0216621","DOIUrl":"https://doi.org/10.1063/5.0216621","url":null,"abstract":"Optical biosensors that consist of a light source, optical elements, and a photodetector are used to detect chemical and biological species and pollutants. This Tutorial discusses the fundamental details of optical biosensing techniques that include materials, working principle, components, sensor configurations, parameters, and future prospects. Optical biosensing techniques include plasmonic [surface plasmon resonance (SPR) and localized SPR], fluorescence, luminescence, Raman scattering, colorimetric, and interferometric methods. Bioreceptor elements play a significant role in detecting the specific analyte that can be synthetic or natural. Surface functionalization techniques to bind the bioreceptor elements on the surface, to control the bioreceptor orientation, have been discussed in detail. The possibility of integration of techniques on a chip, to develop wearable, implantable sensors, and the associated challenges have been fully demonstrated. This Tutorial provides valuable insights into the present state and future directions of optical biosensors for various applications.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"18 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142260589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The manipulation of spin angular momentum for binary circular Airy beam during propagation","authors":"Guang-Bo Zhang, Xu-Zhen Gao, Qing-Lu Li, Ya-Ning Kong, Tian-Fei Zhao, Shi-Tong Xu, Ren-De Ma, Jia-Qi Lü, Yue Pan","doi":"10.1063/5.0223250","DOIUrl":"https://doi.org/10.1063/5.0223250","url":null,"abstract":"The Airy beam has attracted great attention since it was proposed in 2007 due to its novel properties, such as non-diffraction, self-healing, and self-acceleration. However, the spin angular momentum (SAM), which is an intrinsic nature of light, has rarely been studied by the Airy beam. Here, we propose a kind of binary circular Airy beam (BCAB) with space-variant polarizations and vortex phases and study the SAM evolution of the BCAB during propagation. We find the effects of appearance and annihilation of SAM during the propagation of BCAB, and the SAM can be further manipulated by adjusting the initial phase and polarization distribution of BCAB. Moreover, the optical tube, optical needle, and optical cage carrying different SAMs are achieved in propagation, which can be applied in various regions, such as optical trapping and manipulation. The BCAB significantly enriches the family of structured light and provides a flexible control scheme of SAM, which can further promote the application of SAM in many fields.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"36 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142260591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible organic optoelectronic devices: Design, fabrication, and applications","authors":"Yuanhe Wang, Yanlong Wen, Xiaoxiao Zhuang, Shihao Liu, Letian Zhang, Wenfa Xie","doi":"10.1063/5.0220555","DOIUrl":"https://doi.org/10.1063/5.0220555","url":null,"abstract":"Flexible organic optoelectronic devices (FOODs) are rapidly emerging as a transformative technology in consumer electronics due to their exceptional bendability, lightweight, and seamless integration capabilities. This review provides a comprehensive overview of FOODs, including flexible organic light-emitting devices, organic photodetectors, and organic solar cells. We delve into their structural design, fundamental operating principles, and the unique advantages and challenges they present for applications requiring flexibility. Following this, the review explores the critical components of FOODs, with a particular focus on transparent conductive electrodes (TCEs) and innovative substrate materials. We discuss various TCE types, including carbon-based, metal network, and composite designs. Additionally, we explore the use of novel substrates like fibers, fabrics, and paper. Finally, the review examines current fabrication and encapsulation techniques employed for these flexible devices. We conclude by highlighting promising applications of FOODs in diverse fields, including biomedical science and intelligent interactive technologies.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"19 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142260631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond memory-effect matrix-based imaging in scattering media by acousto-optic gating","authors":"Elad Sunray, Gil Weinberg, Moriya Rosenfeld, Ori Katz","doi":"10.1063/5.0219316","DOIUrl":"https://doi.org/10.1063/5.0219316","url":null,"abstract":"Imaging inside scattering media at optical resolution is a longstanding challenge affecting multiple fields, from bio-medicine to astronomy. In recent years, several groundbreaking techniques for imaging inside scattering media, in particular scattering-matrix-based approaches, have shown great promise. However, due to their reliance on the optical “memory-effect,” these techniques usually suffer from a restricted field of view. Here, we demonstrate that diffraction-limited imaging beyond the optical memory-effect can be robustly achieved by combining acousto-optic spatial-gating with state-of-the-art matrix-based imaging techniques. In particular, we show that this can be achieved by computational processing of scattered light fields captured under scanned acousto-optic modulation. The approach can be directly utilized whenever the ultrasound focus size is of the order of the memory-effect range, independently of the scattering angle.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"29 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142260593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A tutorial on optical photothermal infrared (O-PTIR) microscopy","authors":"Craig B. Prater, Mustafa Kansiz, Ji-Xin Cheng","doi":"10.1063/5.0219983","DOIUrl":"https://doi.org/10.1063/5.0219983","url":null,"abstract":"This tutorial reviews the rapidly growing field of optical photothermal infrared (O-PTIR) spectroscopy and chemical imaging. O-PTIR is an infrared super-resolution measurement technique where a shorter wavelength visible probe is used to measure and map infrared (IR) absorption with spatial resolution up to 30× better than conventional techniques such as Fourier transform infrared and direct IR laser imaging systems. This article reviews key limitations of conventional IR instruments, the O-PTIR technology breakthroughs, and their origins that have overcome the prior limitations. This article also discusses recent developments in expanding multi-modal O-PTIR approaches that enable complementary Raman spectroscopy and fluorescence microscopy imaging, including wide-field O-PTIR imaging with fluorescence-based detection of IR absorption. Various practical subjects are covered, including sample preparation techniques, optimal measurement configurations, use of IR tags/labels and techniques for data analysis, and visualization. Key O-PTIR applications are reviewed in many areas, including biological and biomedical sciences, environmental and microplastics research, (bio)pharmaceuticals, materials science, cultural heritage, forensics, photonics, and failure analysis.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"86 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142260592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cascade amplification-based triple probe biosensor for high-precision DNA hybridization detection of lung cancer gene","authors":"Zhiyong Yin, Xili Jing, Shuguang Li","doi":"10.1063/5.0228760","DOIUrl":"https://doi.org/10.1063/5.0228760","url":null,"abstract":"As an essential biomarker for diagnosing and treating various diseases, low-cost, quantitative detection methods for complementary DNA (cDNA) have received much attention. The surface plasmon resonance (SPR) sensing technique is an effective measurement scheme, but the ambient temperature and pH variations have a non-negligible impact. In this work, we developed a triple-probe SPR sensing system for detecting cDNA concentration, temperature, and pH. In order to satisfy the triple parameter measurements, we used a microstructured optical fiber as the sensing platform, silver and gold films as the excitation layer, and a MoS2 film as the modulation layer. First, we explore the modulation mechanism of SPR and the conditions for excitation of triple SPR and demonstrate that the carrier concentration is a crucial factor affecting the resonance wavelength. Then, the feasibility of the sensing system for triple-probing is theoretically analyzed. Finally, in the experiment, the optimal parameters of the sensor were determined, and the triple parameter detection was successfully realized. The experimental results show that the three probes can work independently, and the hybridized DNA probe can realize the selective detection of cDNA with a sensitivity of 0.249 nm/(nmol/l). The maximum sensitivity of the pH probe and the temperature probe are 51.5 nm/pH and 6.14 nm/°C. In addition, the experimental results show that the sensing probes have excellent reproducibility. This paper’s innovation is using the fiber optic SPR effect to achieve quantitative detection for cDNA, temperature detection, and pH detection. Therefore, the sensor has a promising future in early diagnosis and biosensing.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"35 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative assessment of chlorine gas inhalation injury based on endoscopic OCT and spectral encoded interferometric microscope imaging with deep learning","authors":"Zhikai Zhu, Hyunmo Yang, Hongqiu Lei, Yusi Miao, George Philipopoulos, Melody Doosty, David Mukai, Yuchen Song, Jangwoen Lee, Sari Mahon, Matthew Brenner, Livia Veress, Carl White, Woonggyu Jung, Zhongping Chen","doi":"10.1063/5.0222153","DOIUrl":"https://doi.org/10.1063/5.0222153","url":null,"abstract":"Chlorine exposure can cause severe airway injuries. While the acute effects of chlorine inhalation are well-documented, the structural changes resulting from the post-acute, high-level chlorine exposure remain less understood. Airway sloughing is one of the standards for doctors to evaluate the lung function. Here, we report the application of a high-resolution swept-source optical coherence tomography system to investigate the progression of injury based on airway sloughing evaluation in a chlorine inhalation rabbit model. This system employs a 1.2 mm diameter flexible fiberoptic endoscopic probe via an endotracheal tube to capture in vivo large airway anatomical changes before and as early as 30 min after acute chlorine exposure. We conducted an animal study using New Zealand white rabbits exposed to acute chlorine gas (800 ppm, 6 min) during ventilation and monitored them using optical coherence tomography (OCT) for 6 h. To measure the volume of airway sloughing induced by chlorine gas, we utilized deep learning for the segmentation task on OCT images. The results showed that the volume of chlorine induced epithelial sloughing on rabbit tracheal walls initially increased, peaked around 30 min, and then decreased. Furthermore, we utilized a spectral encoded interferometric microscopy system to study ex vivo airway cilia beating dynamics based on Doppler shift, aiding in elucidating how chlorine gas affects cilia beating function. Cilia movability and beating frequency were decreased because of the epithelium damage. This quantitative approach has the potential to enhance the diagnosis and monitoring of injuries from toxic gas inhalation and to evaluate the efficacy of antidote treatments for these injuries.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"6 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Widely tunable Ka-band optoelectronic oscillator integrated on thin film lithium niobate platform","authors":"Rui Ma, Zijun Huang, Wei Ke, Xichen Wang, Peng Hao, X. Steve Yao, Xinlun Cai","doi":"10.1063/5.0214107","DOIUrl":"https://doi.org/10.1063/5.0214107","url":null,"abstract":"We report a novel widely tunable Ka-band optoelectronic oscillator (OEO) realized by integrating a Mach–Zehnder modulator (MZM), a thermally-tunable add-drop micro-ring resonator (MRR), and a Mach–Zehnder interferometer (MZI) on the thin film lithium niobate platform, with the MZM and the MRR sequentially situated in one of the MZI arms. The MZM is for modulating the optical carrier, while the add-drop MRR is for selecting a single modulation sideband to beat with the unmodulated optical carrier from the other arm of the MZI, such that the OEO oscillation frequency is determined by the frequency spacing between the optical carrier and the selected modulation sideband, while the frequency tuning range is determined by the free spectral range of the MRR. By tuning the resonances of the add-drop MRR, the oscillation frequency can be tuned from 20 to 35 GHz, with the phase noises of −85 dBc/Hz @10 kHz and −116 dBc/Hz @100 kHz in the whole tuning range, which represent much higher oscillation frequency, much wider frequency tuning range, and lower phase noise than those of the photonic integrated OEOs realized with other material platforms reported previously.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"10 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open-path detection of organic vapors via quantum infrared spectroscopy","authors":"Simon Neves, Adimulya Kartiyasa, Shayantani Ghosh, Geoffrey Gaulier, Luca La Volpe, Jean-Pierre Wolf","doi":"10.1063/5.0220707","DOIUrl":"https://doi.org/10.1063/5.0220707","url":null,"abstract":"In recent years, quantum Fourier transform infrared (QFTIR) spectroscopy has emerged as an alternative to conventional absorption spectroscopy in the mid-infrared region of the spectrum. By harnessing induced coherence and spectral correlations of photon pairs in a nonlinear Michelson interferometer, this technique offers promising potential for the practical detection of organic gases. However, little research was conducted to bring QFTIR spectrometers closer to domestic or in-field usage. In this work, we present the first use of a QFTIR spectrometer for open-path detection of multiple interfering organic gases in ambient air. We built a nonlinear Michelson interferometer with 1.7 m-long arms to increase the absorption length, coupled with analysis techniques from classical differential absorption spectroscopy used for gas-traces detection. We thus characterize our spectrometer’s sensitivity to acetone, methanol, and ethanol vapors and demonstrate the accurate identification of mixtures of these gases released in ambient air. We show this characteristic is preserved over time by performing a measurement overnight and tracking the evolution of different gases’ average concentrations. These results constitute the first use-case of a QFTIR spectrometer as a detector of organic gases and, thus, represent an important milestone toward the development of such detectors in practical situations.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"58 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}