APL Photonics最新文献_第2页

Chaotic dynamics in passively Q-switched Tm:LiYF4 laser operating at 2.3 μm on the 3H4 → 3H5 transition 工作波长为 2.3 μm 的无源 Q 开关 Tm:LiYF4 激光器中 3H4 → 3H5 转变的混沌动力学

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-05 DOI: 10.1063/5.0220220

Hippolyte Dupont, Matthieu Glasset, Pavel Loiko, Patrick Georges, Frédéric Druon

引用次数: 0

Rapid and precise multifocal cutaneous tumor margin assessment using fluorescence lifetime detection and machine learning 利用荧光寿命检测和机器学习对多灶性皮肤肿瘤边缘进行快速、精确的评估

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-05 DOI: 10.1063/5.0224181

Wenhua Su, Dachao Zheng, Jiacheng Zhou, Qiushu Chen, Liwen Chen, Yuwei Yang, Yiyan Fei, Haijun Yao, Jiong Ma, Lan Mi

{"title":"Rapid and precise multifocal cutaneous tumor margin assessment using fluorescence lifetime detection and machine learning","authors":"Wenhua Su, Dachao Zheng, Jiacheng Zhou, Qiushu Chen, Liwen Chen, Yuwei Yang, Yiyan Fei, Haijun Yao, Jiong Ma, Lan Mi","doi":"10.1063/5.0224181","DOIUrl":"https://doi.org/10.1063/5.0224181","url":null,"abstract":"The precise determination of surgical margins is essential for the management of multifocal cutaneous cancers, including extramammary Paget’s disease. This study introduces a novel strategy for precise margin identification in such tumors, employing multichannel autofluorescence lifetime decay (MALD), fluorescence lifetime imaging microscopy (FLIM), and machine learning, including confidence learning algorithms. Using FLIM, 51 unstained frozen sections were analyzed, of which 13 (25%) sections, containing 5003 FLIM patches, were used for training the residual network model (ResNet–FLIM). The remaining 38 (75%) sections, including 16 918 patches, were retained for external validation. Application of confidence learning with deep learning reduced the reliance on extensive pathologist annotation. Refined labels obtained by ResNet–FLIM were then incorporated into a support vector machine (SVM) model, which utilized fiber-optic-based MALD data. Both models exhibited substantial agreement with the pathological assessments. Of the 35 MALD-measured tissue segments, six (17%) segments were selected as the training dataset, including 900 decay profiles. The remaining 29 segments (83%), including 2406 decay profiles, were reserved for external validation. The ResNet–FLIM model achieved 100% sensitivity and specificity. The SVM–MALD model demonstrated 94% sensitivity and 83% specificity. Notably, fiber-optic-MALD allows assessing 12 sites per patient and delivering predictions within 10 min. Variations in the necessary safe margin length were observed among patients, highlighting the necessity for patient-specific approaches to determine surgical margins. This innovative approach holds potential for wide clinical application, providing a rapid and accurate margin evaluation method that significantly reduces a pathologist’s workload and improves patient outcomes through personalized medicine.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"72 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-wavelength, nanosecond, miniature Raman laser enables efficient photoacoustic differentiation of water and lipid 双波长、纳秒级微型拉曼激光器可实现水和脂质的高效光声区分

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-04 DOI: 10.1063/5.0216255

Hanjie Wang, Lin Zhao, Huiyue You, Huiling Wu, Qingliang Zhao, Xin Dong, Shengchuang Bai, Hongsen He, Jun Dong

引用次数: 0

Piezoelectrically driven Fano resonance in silicon photonics 硅光子学中的压电驱动法诺共振

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-04 DOI: 10.1063/5.0207482

I. Ansari, G. F. Feutmba, J. P. George, H. Rijckaert, J. Beeckman, D. Van Thourhout

{"title":"Piezoelectrically driven Fano resonance in silicon photonics","authors":"I. Ansari, G. F. Feutmba, J. P. George, H. Rijckaert, J. Beeckman, D. Van Thourhout","doi":"10.1063/5.0207482","DOIUrl":"https://doi.org/10.1063/5.0207482","url":null,"abstract":"Piezoelectric optomechanical platforms provide a promising avenue for efficient signal transduction between microwave and optical domains. Lead zirconate titanate (PZT) thin film stands out as a compelling choice for building such a platform given its high piezoelectricity and optical transparency, enabling strong electro-optomechanical transduction. This work explores the application of such transduction to induce Fano resonance in a silicon photonics integrated circuit (PIC). Our methodology involves integrating a PZT thin film onto a silicon PIC and subsequently removing the SiO2 layer to suspend the silicon waveguide, allowing controlled mechanical vibrations. Fano resonances, characterized by their distinctive asymmetric line shape, were observed at frequencies up to 6.7 GHz with an extinction ratio of 21 dB. A high extinction ratio of 41 dB was achieved at the lower resonance frequency of 223 MHz. Our results demonstrate the potential of piezoelectric thin film integration for the generation of Fano resonances on passive photonic platforms such as Si, paving the way for highly sensitive, compact, and power-efficient devices relevant to a wide range of applications.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"35 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multimodal optical ultrasound imaging: Real-time imaging under concurrent CT or MRI 多模式光学超声成像：同步 CT 或 MRI 下的实时成像

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-03 DOI: 10.1063/5.0225554

Fraser T. Watt, Vivek Muthurangu, Jennifer Steeden, Eleanor C. Mackle, Adrien E. Desjardins, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles

{"title":"Multimodal optical ultrasound imaging: Real-time imaging under concurrent CT or MRI","authors":"Fraser T. Watt, Vivek Muthurangu, Jennifer Steeden, Eleanor C. Mackle, Adrien E. Desjardins, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles","doi":"10.1063/5.0225554","DOIUrl":"https://doi.org/10.1063/5.0225554","url":null,"abstract":"Optical ultrasound (OpUS) imaging is an ultrasound modality that utilizes fiber-optic ultrasound sources and detectors to perform pulse-echo ultrasound imaging. These probes can be constructed entirely from glass optical fibers and plastic components, and as such, these devices have been predicted to be compatible with computed tomography (CT) and magnetic resonance imaging (MRI), modalities that use intense electromagnetic fields for imaging. However, to date, this compatibility has not been demonstrated. In this work, a free-hand OpUS imaging system was developed specifically to investigate the compatibility of OpUS systems with CT and MRI imaging systems. The OpUS imaging platform discussed in this work was used to perform real-time OpUS imaging under (separately) concurrent CT and MRI. CT and MRI imaging of the OpUS probe was used to determine if the probe itself would induce artifacts in the CT and MRI imaging, and ultrasound resolution targets and background measurements were used to assess any impact of CT and MRI on the OpUS signal fidelity. These measurements demonstrate that there was negligible interaction between the OpUS system and both the CT and MRI systems, and to further demonstrate this capability, concurrent OpUS-CT and OpUS-MRI imaging was conducted of a tissue-mimicking phantom and a dynamic motion phantom. This work presents a comprehensive demonstration of an OpUS imaging system operating alongside CT and MRI, which opens up new applications of ultrasound imaging in electromagnetically challenging settings.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"144 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mid-infrared waveguide-integrated and photo-thermoelectric graphene photodetector based on germanium-on-silicon platform 基于硅基锗平台的中红外波导集成和光热电石墨烯光电探测器

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-03 DOI: 10.1063/5.0218976

Hongjun Cai, Changming Yang, Yuheng Liu, Xinliang Zhang, Yi Zou, Yu Yu

{"title":"Mid-infrared waveguide-integrated and photo-thermoelectric graphene photodetector based on germanium-on-silicon platform","authors":"Hongjun Cai, Changming Yang, Yuheng Liu, Xinliang Zhang, Yi Zou, Yu Yu","doi":"10.1063/5.0218976","DOIUrl":"https://doi.org/10.1063/5.0218976","url":null,"abstract":"Mid-infrared (MIR) photonic integration is desirable in the development of MIR spectroscopy and “lab-on-a-chip” sensing. The germanium-on-silicon (GOS) platform offers a promising solution for MIR photonic integration, extending the operational wavelength to a longer band by eliminating the light-absorbing buried oxide layer. However, MIR photodetectors on the GOS platform remain undeveloped due to the challenging heterogeneous integration of active materials on silicon and inadequate light absorption in the photodetection region. Here, we demonstrate a photo-thermoelectric graphene photodetector on the GOS platform, taking advantage of zero-bias operation and easy heterogeneous integration of graphene. By employing split-gate architecture and plasmonic enhancement to strengthen the light-graphene interaction, we achieve a responsivity of 1.97 V W−1 and noise equivalent power of 2.8 nW Hz−1/2 at the wavelength of 3.7 µm. This work enables waveguide-integrated MIR photodetection on the GOS platform for the first time, and it holds great potential for on-chip MIR sensing and imaging applications.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"14 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-wavelength, high-resolution microscopy using upconversion in ultra-thin crystals 利用超薄晶体中的上转换技术实现长波长、高分辨率显微技术

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-09-03 DOI: 10.1063/5.0217145

P. Tidemand-Lichtenberg, C. Pedersen

引用次数: 0

Deep-ultraviolet Fourier ptychography (DUV-FP) for label-free biochemical imaging via feature-domain optimization. 通过特征域优化实现无标记生化成像的深紫外傅立叶层析成像（DUV-FP）。

IF 5.4 1区物理与天体物理

APL Photonics Pub Date : 2024-09-01 Epub Date: 2024-09-16 DOI: 10.1063/5.0227038

Qianhao Zhao, Ruihai Wang, Shuhe Zhang, Tianbo Wang, Pengming Song, Guoan Zheng

{"title":"Deep-ultraviolet Fourier ptychography (DUV-FP) for label-free biochemical imaging via feature-domain optimization.","authors":"Qianhao Zhao, Ruihai Wang, Shuhe Zhang, Tianbo Wang, Pengming Song, Guoan Zheng","doi":"10.1063/5.0227038","DOIUrl":"https://doi.org/10.1063/5.0227038","url":null,"abstract":"<p><p>We present deep-ultraviolet Fourier ptychography (DUV-FP) for high-resolution chemical imaging of biological specimens in their native state without exogenous stains. This approach uses a customized 265-nm DUV LED array for angle-varied illumination, leveraging the unique DUV absorption properties of biomolecules at this wavelength region. We implemented a robust feature-domain optimization framework to overcome common challenges in Fourier ptychographic reconstruction, including vignetting, pupil aberrations, stray light problems, intensity variations, and other systematic errors. By using a 0.12 numerical aperture low-resolution objective lens, our DUV-FP prototype can resolve the 345-nm linewidth on a resolution target, demonstrating at least a four-fold resolution gain compared to the captured raw images. Testing on various biospecimens demonstrates that DUV-FP significantly enhances absorption-based chemical contrast and reveals detailed structural and molecular information. To further address the limitations of conventional FP in quantitative phase imaging, we developed a spatially coded DUV-FP system. This platform enables true quantitative phase imaging of biospecimens with DUV light, overcoming the non-uniform phase response inherent in traditional microscopy techniques. The demonstrated advancements in high-resolution, label-free chemical imaging may accelerate developments in digital pathology, potentially enabling rapid, on-site analysis of biopsy samples in clinical settings.</p>","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"9 9","pages":"090801"},"PeriodicalIF":5.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11409226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

π mode lasing in the non-Hermitian Floquet topological system 非ermitian Floquet 拓扑系统中的π模激光

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-08-30 DOI: 10.1063/5.0217904

Shuang Shen, Yaroslav V. Kartashov, Yongdong Li, Meng Cao, Yiqi Zhang

{"title":"π mode lasing in the non-Hermitian Floquet topological system","authors":"Shuang Shen, Yaroslav V. Kartashov, Yongdong Li, Meng Cao, Yiqi Zhang","doi":"10.1063/5.0217904","DOIUrl":"https://doi.org/10.1063/5.0217904","url":null,"abstract":"π modes are unique topological edge states appearing in Floquet systems with periodic modulations of the underlying lattice structure in the evolution variable, such as dynamically modulated Su–Schrieffer–Heeger (SSH) lattices. These edge states are anomalous states usually appearing between Floquet replicas of the same band, even if the standard topological index remains zero for this band. While linear and nonlinear π modes were observed in conservative systems, they have never been studied in the nonlinear regime in the non-Hermitian systems with structured gain and losses. Here, we show that the SSH waveguide array with periodically oscillating waveguide positions in the propagation direction and with the parity-time symmetric refractive index landscape can support π modes that are damped or amplified at different ends of the array. By including nonlinearity and nonlinear absorption into our continuous system, we achieve stable lasing in the π mode at one end of the array. The representative feature of this system is that lasing in it is thresholdless and occurs even at low gain–loss amplitudes. The degree of localization of lasing π modes can be flexibly controlled by the amplitude of transverse waveguide oscillations. This work therefore introduces a new type of topological Floquet laser and a route to manipulate π modes by structured gain and losses.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"4 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Embedding FBG sensors for monitoring vital signs of the human body: Recent progress over the past decade 嵌入 FBG 传感器监测人体生命体征：过去十年的最新进展

IF 5.6 1区物理与天体物理

APL Photonics Pub Date : 2024-08-30 DOI: 10.1063/5.0226556

Daniel Krizan, Jiri Stipal, Jan Nedoma, Sandro Oliveira, Marcel Fajkus, Jakub Cubik, Petr Siska, Emiliano Schena, Daniela Lo Presti, Carlos Marques

{"title":"Embedding FBG sensors for monitoring vital signs of the human body: Recent progress over the past decade","authors":"Daniel Krizan, Jiri Stipal, Jan Nedoma, Sandro Oliveira, Marcel Fajkus, Jakub Cubik, Petr Siska, Emiliano Schena, Daniela Lo Presti, Carlos Marques","doi":"10.1063/5.0226556","DOIUrl":"https://doi.org/10.1063/5.0226556","url":null,"abstract":"Fiber optic sensors based on fiber Bragg grating (FBG) technology have the potential to revolutionize the way vital signs of the human body are measured and monitored. By leveraging their unique properties, these sensors can provide accurate and reliable data, thus enhancing the effectiveness of wearable devices. The integration of FBG sensors into different materials not only broadens their application scope but also improves user comfort and device practicality. However, some challenges remain in optimizing the embedding process to ensure sensor performance and durability. This review provides an overview of FBG technology employed for measuring vital signs of the human body reported in the past decade. The focus of the review is on the FBG embedding strategies into different materials, categorized into these three main groups (i.e., 3D printed, textiles, and polymers) and explores the implications of embedding fiber optic sensors in each category. Furthermore, it discusses the potential impact of these embedded sensors on the accuracy, comfort, and practicality of wearable devices designed for monitoring vital signs, highlighting the potential of these sensors to transform the field of health monitoring. Future research directions may include exploring new materials for embedding and refining sensor design further to improve the accuracy and comfort of these wearable devices. Ultimately, the evolution of fiber optic sensors could significantly advance the field of human vital sign monitoring, paving the way for more sophisticated and user-friendly health monitoring systems.","PeriodicalId":8198,"journal":{"name":"APL Photonics","volume":"10 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142199475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0