European heart journal. Digital health最新文献

{"title":"Meet key digital health thought leaders: Sandy Engelhardt, Scientific Program Chair of the ESC's Digital Summit 2025.","authors":"Nico Bruining","doi":"10.1093/ehjdh/ztaf060","DOIUrl":"https://doi.org/10.1093/ehjdh/ztaf060","url":null,"abstract":"","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"519-520"},"PeriodicalIF":3.9,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance and safety of a novel, cable-free, patch-based, and AI-enhanced ECG monitoring system: a comparative study.","authors":"Owain Thomas, Rikard Linnér, Alain Dardashti","doi":"10.1093/ehjdh/ztaf059","DOIUrl":"10.1093/ehjdh/ztaf059","url":null,"abstract":"<p><strong>Aims: </strong>ECG monitoring is often required during critical phases of illness. To evaluate the role of modern technology and advanced analytical algorithms artificial intelligence compared with standard-of care, we undertook a prospective, head-to-head comparison of a novel, cable-free, patch-based, and AI-enhanced electrocardiography system (CardioSenseSystem) with standard of care (SOC) ECG monitoring. Patients who had undergone cardiac surgery at a large university hospital (Skåne University Hospital, Sweden) were simultaneously monitored by both systems, and alarms and monitoring interruptions were recorded.</p><p><strong>Methods and results: </strong>Forty-nine patients were recruited. The CardioSenseSystem system demonstrated significantly higher sensitivity, correctly detecting 364 critical red alarms vs. 12 for SOC (<i>P</i> < 0.0001), and lower rates of high priority false alarms (0.3% vs. 40%; <i>P</i> < 0.0001). Monitoring interruptions were markedly reduced (114 s/day vs. 584 s/day; <i>P</i> < 0.0001). Handling time per patient day was significantly shorter (256 s vs. 880 s). The CardioSenseSystem system also reduced alarm fatigue, with fewer disturbances per patient per hour (0.03 vs. 0.11; <i>P</i> < 0.0001).</p><p><strong>Conclusion: </strong>The CardioSenseSystem system delivered significant advantages over conventional ECG monitoring in post-cardiac surgery patients. Its high sensitivity, reduced false alarms, fewer monitoring interruptions, and decreased handling time suggest that it may enhance patient outcomes and clinical efficiency, warranting broader application in acute-care settings.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 5","pages":"888-896"},"PeriodicalIF":4.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12450504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The inclusion of a Holter Reading software in the clinical practice of cardiology shows a multi-level high positive impact in healthcare: a real-world implementation study in three Spanish hospitals.","authors":"Juan Antonio Álvaro de la Parra, Francisco de Asis Diaz-Cortegana, David Gonzalez-Casal, Petra Sanz-Mayordomo, Jose-Angel Cabrera, Jose Manuel Rubio Campal, Bernadette Pfang, Ion Cristóbal, Cristina Caramés, María Elvira Barrios Garrido-Lestache","doi":"10.1093/ehjdh/ztaf058","DOIUrl":"10.1093/ehjdh/ztaf058","url":null,"abstract":"<p><strong>Aims: </strong>Holter monitoring is a high prevalent technique to detect various heart pathologies. Its use has progressively increased over time with the consequent expenditure of time to interpret its results. We aim to evaluate the validity of the Cardiologs software as well as the clinical utility and potential benefits derived from the inclusion of an artificial intelligence (AI)-based software in the clinical routine of the cardiology service.</p><p><strong>Methods and results: </strong>Concordance analyses were performed to determine the degree of correlation between the results reported by the Cardiologs software and cardiologists regarding a list of variables for 498 Holter records included in the study. Sensitivity, specificity, positive and negative prediction values, positive and negative likelihood ratios, and odds ratio were calculated. The preliminary analysis reported good correlation between the reported observations by the cardiologists involved in this study (Kappa = 0.67; <i>P</i> < 0001). Furthermore, an excellent concordance was found between software and cardiologists in the detection of atrial fibrillation, ventricular extrasystoles and sinus pauses of >3 s, moderate for supraventricular extrasystoles (Kappa > 0.80 in all cases), but weak or poor correlations in the rest of the variables studied. The global correlation was moderate (Kappa = 0.43; <i>P</i> < 0.001). Notably, the software showed sensitivity of 99.4%, negative predictive value of 99.5%, and negative likelihood ratio of 0.010, highlighting its clinical usefulness in correctly identify normal tests.</p><p><strong>Conclusion: </strong>The inclusion of an AI-based software for reading Holter tests may have great impact in distinguishing normal Holter tests, leading to time savings and improved clinical efficiency.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"742-748"},"PeriodicalIF":3.9,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photoplethysmography in recent-onset atrial fibrillation: automatic detection of rhythm change and burden.","authors":"Olli A Rantula, Jukka A Lipponen, Jari Halonen, Helena Jäntti, Tuomas T Rissanen, Noora S Naukkarinen, Eemu-Samuli Väliaho, Onni E Santala, Jagdeep Sedha, Tero J Martikainen, Juha E K Hartikainen","doi":"10.1093/ehjdh/ztaf055","DOIUrl":"10.1093/ehjdh/ztaf055","url":null,"abstract":"<p><strong>Aims: </strong>Atrial fibrillation (AF) is the most common arrhythmia, increasing stroke risk. Detecting AF is challenging due to its asymptomatic and paroxysmal nature. This study combines photoplethysmography (PPG) with automated techniques to detect AF, assess AF burden, and monitor rhythm changes from AF to sinus rhythm (SR).</p><p><strong>Methods and results: </strong>Ninety patients with recent-onset (duration <48 h) AF, scheduled for cardioversion, were monitored using a three-channel PPG armband on the upper arm. An ambulatory three-lead electrocardiogram (ECG) served as the gold standard. PPG recordings were segmented into 10-, 20-, 30-, and 60-min detection windows. Automated detection identified SR and AF episodes, rhythm changes, and AF burden. Sensitivities, specificities, positive predictive values (PPVs), and negative predictive values (NPVs) for rhythm detection were calculated, and the intraclass correlation coefficients (ICCs) for PPG-based AF burden were compared to the gold standard. Monitoring time ranged from 1.0 to 8.2 h per patient. Sensitivities, specificities, PPVs, and NPVs for AF detection were 93.9-94.6, 99.5-99.8, 99.4-99.7, and 93.7-95.0%, respectively. The ICC (0.97-0.98) indicated excellent agreement between PPG and the gold standard in estimating AF burden, with differences of -6.3 to -8.3 min (5.5-6.8%). Rhythm changes from AF to SR were detected in all patients (sensitivity 100%), with detection delays of 4.1 ± 1.4, 8.7 ± 2.8, 13.7 ± 3.9, and 27.8 ± 7.1 min depending on the detection window.</p><p><strong>Conclusion: </strong>Photoplethysmography with automated analysis shows promise in detecting AF, AF burden, and rhythm changes, indicating its potential in AF screening.</p><p><strong>Clinical trial registration: </strong>NCT04917653.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"723-732"},"PeriodicalIF":3.9,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A deep foundation model for electrocardiogram interpretation: enabling rare disease detection through transfer learning.","authors":"Stephanie M Hu, Joshua P Barrios, Geoffrey H Tison","doi":"10.1093/ehjdh/ztaf051","DOIUrl":"10.1093/ehjdh/ztaf051","url":null,"abstract":"<p><p>In healthcare, scarcity of high-quality human-adjudicated labelled data may limit the potential of deep neural networks (DNNs). Foundation models provide an efficient starting point for deep learning that can facilitate effective DNN training with fewer labelled training examples. In this study, we leveraged cardiologist-confirmed labels from a large dataset of 1.6 million electrocardiograms (ECGs) acquired as part of routine clinical care at UCSF between 1986 and 2019 to pre-train a convolutional DNN to predict 68 common ECG diagnoses. To our knowledge, this model is one of the most comprehensive ECG DNN models to date, demonstrating high performance with a median area under the receiver operating curve (AUC) of 0.978, median sensitivity of 0.937, and median specificity of 0.923. We then demonstrate the model's utility as a foundation model by additionally training (fine-tuning) the DNN to detect three novel ECG diagnoses with relatively small datasets: carcinoid syndrome, pericardial constriction, and rheumatic doming of the mitral valve. Fine-tuning training of the foundation model achieved an AUC of 0.772 (95% CI 0.723-0.816) for carcinoid syndrome, 0.883 (0.863-0.906) for pericardial constriction, and 0.826 (95% CI 0.802-0.854) for rheumatic doming, compared to 0.492 (95% CI 0.434-0.558), 0.689 (95% CI 0.656-0.720), and 0.701 (95% CI 0.657-0.745), respectively, for DNNs trained from scratch on the same small datasets. Our results demonstrate that the ECG foundation model learned a flexible representation of ECG waveforms and can improve performance of fine-tuned downstream models, particularly in data-limited settings.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"619-623"},"PeriodicalIF":4.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new wearable e monitoring technology for evaluation of left ventricular remodeling after transcatheter aortic valve replacement.","authors":"Ran Liu, Qiang Li, Yang Li, Zhaolin Fu, Meng Xie, Xiaowei Yan, Zhinan Lu, Guangyuan Song","doi":"10.1093/ehjdh/ztaf050","DOIUrl":"10.1093/ehjdh/ztaf050","url":null,"abstract":"<p><strong>Aims: </strong>Pathological left ventricular (LV) remodelling following aortic stenosis (AS) confers high risk for heart failure and significantly decreases survival. This study aims to introduce a new wearable acoustic cardiography (ACG) device measuring electromechanical activation time (EMAT) to identify the regression of cardiac remodelling in AS patients undergoing transcatheter aortic valve replacement (TAVR).</p><p><strong>Methods and results: </strong>This prospective cohort study consecutively enrolled patients with severe symptomatic AS who underwent successful TAVR. The parameters EMAT and EMAT% (EMAT divided by R-R interval, expressed as a percentage) derived from ACG as well as echocardiography data were collected. Pearson correlation analysis was performed to evaluate the correlation between EMAT% and left ventricular mass index (LVMi). Receiver operating characteristic (ROC) curves were used to assess the diagnostic performance of EMAT% in predicting left ventricular hypertrophy (LVH). A total of 159 patients (mean age 72.0 years) were enrolled in the study. At baseline, 55% of patients demonstrated severe LV remodelling. Scatter plots and Pearson correlation analysis revealed a significant association between EMAT% and LVMi. The ROC curve analysis showed strong diagnostic performance of EMAT% in predicting LVH, with an area under the curve consistently exceeding 80% at baseline and during follow-up. Both EMAT% and echocardiographic parameters indicated that LV remodelling progressively improved between 1 and 6 months after TAVR, with stabilization observed at 12 months.</p><p><strong>Conclusion: </strong>The EMAT can be considered as an effective tool to assist in the evaluation of LV remodelling after TAVR. Further studies are required to confirm its utility as a valuable non-invasive diagnostic and monitoring tool.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"713-722"},"PeriodicalIF":3.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence-estimated electrocardiographic sex as a recurrence predictor after atrial fibrillation catheter ablation.","authors":"Hanjin Park, Oh-Seok Kwon, Jaemin Shim, Daehoon Kim, Je-Wook Park, Yun-Gi Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Il Choi, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak","doi":"10.1093/ehjdh/ztaf054","DOIUrl":"10.1093/ehjdh/ztaf054","url":null,"abstract":"<p><strong>Aims: </strong>We explored whether artificial intelligence (AI)-enabled electrocardiographic (ECG) sex discrepancy would predict atrial fibrillation (AF) recurrence after catheter ablation for paroxysmal AF.</p><p><strong>Methods and results: </strong>The AI-ECG sex prediction model was developed from the MIMIC-IV and externally validated on CODE-15% (AUC 0.89) and UK Biobank (AUC 0.92) cohorts. After validation, we estimated AI-ECG sex from pre-procedural sinus rhythm ECGs among paroxysmal AF patients scheduled for catheter ablation using data from a pooled AF ablation cohort (<i>n</i> = 4385) in South Korea. ECG sex discrepancy was defined as ECG sex probability of more than 50% for the opposite sex. During a median follow-up of 24 months, 1094 recurrences developed [median age 60 (52-67) years; women 29.0%]. ECG sex discrepant patients were older, had more heart failure, and had elevated diastolic filling pressure compared with ECG sex non-discrepant patients. The odds ratio (OR) for left atrial enlargement was significantly higher among ECG sex discrepant women [adjusted OR 1.67, 95% confidence interval (CI) 1.14-2.44, <i>P</i> = 0.008] but not among men (adjusted OR 0.88, 95% CI 0.66-1.17, <i>P</i> = 0.368). The 5-year cumulative event rate of AF recurrence was significantly higher among ECG sex discrepant women (log rank, <i>P</i> = 0.015) but not among men (log rank, <i>P</i> = 0.871). The 5-year risk of AF recurrence was significantly higher among ECG sex discrepant women [hazard ratio (HR) 1.42, 95% CI 1.10-1.83, <i>P</i> = 0.007] but not among men (HR 1.01, 95% CI 0.76-1.34, <i>P</i> = 0.940).</p><p><strong>Conclusion: </strong>Pre-procedural ECG sex discrepancy has a prognostic value for AF recurrence after catheter ablation for paroxysmal AF in women.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"624-634"},"PeriodicalIF":3.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review and recommendations for using artificial intelligence in intracoronary optical coherence tomography analysis.","authors":"Xu Chen, Yuan Huang, Benn Jessney, Jason Sangha, Sophie Gu, Carola-Bibiane Schönlieb, Martin Bennett, Michael Roberts","doi":"10.1093/ehjdh/ztaf053","DOIUrl":"10.1093/ehjdh/ztaf053","url":null,"abstract":"<p><p>Artificial intelligence (AI) tools hold great promise for the rapid and accurate diagnosis of coronary artery disease (CAD) from intravascular optical coherent tomography (IVOCT) images. Numerous papers have been published describing AI-based models for different diagnostic tasks, yet it remains unclear, which models have potential clinical utility and have been properly validated. This systematic review considered published literature between January 2015 and December 2024 describing AI-based diagnosis of CAD using IVOCT. Our search identified 8600 studies, with 629 included after initial screening and 39 studies included in the final systematic review after quality screening. Our findings indicate that most of the identified models are not currently suitable for clinical use, primarily due to methodological flaws and underlying biases. To address these issues, we provide recommendations to improve model quality and research practices to enhance the development of clinically useful AI products.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"529-539"},"PeriodicalIF":3.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the digital health readiness questionnaire Japanese version: insights from cardiovascular patients in Japan.","authors":"Sanami Ozaki, Toshiki Kaihara, Yoshihiro Akashi","doi":"10.1093/ehjdh/ztaf026","DOIUrl":"10.1093/ehjdh/ztaf026","url":null,"abstract":"<p><strong>Aims: </strong>The COVID-19 pandemic has raised patient awareness of their health and highlighted the importance of remote care. Smartphones and wearable devices are now becoming essential for managing cardiovascular disease. However, low digital health readiness among cardiology patients poses a significant challenge to the effective use of these technologies. This study evaluates digital health readiness and learning ability of Japanese cardiology patients using the Digital Health Readiness Questionnaire (DHRQ), while also assessing its reliability and validity.</p><p><strong>Methods and results: </strong>This multicentre observational study evaluated digital health readiness among patients with cardiovascular risk factors at St. Marianna University Hospital and Kawasaki Municipal Tama Hospital. The DHRQ was employed, and confirmatory factor analysis was conducted to validate the measurement model. A total of 210 questionnaires were distributed, with 208 included in the analysis. Internal consistency, measured by Cronbach's alpha, exceeded 0.7 across all factors. Model fit was evaluated with standardised root mean square residual = 0.038, root mean square error of approximation = 0.071, comparative fit index = 0.962, and Tucker-Lewis index = 0.955. Age, education, and smartphone/smartwatch ownership significantly predicted higher DHRQ scores. Older age correlated with lower scores (<i>P</i> < 0.001), while higher education, smartphone (<i>P</i> < 0.001), and smartwatch ownership (<i>P</i> = 0.006) correlated with higher scores. Gender and income were not significant.</p><p><strong>Conclusion: </strong>The DHRQ proved to be valid in Japan, with education level significantly affecting scores. Improved digital health readiness is suggested to enhance patients' management of health information and communication with healthcare providers, and is expected to be linked to future healthcare systems.</p>","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"849-852"},"PeriodicalIF":3.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of artificial intelligence-enhanced electrocardiography approaches for the prediction of time to mortality using electrocardiogram images: reply.","authors":"Partha Pratim Ray","doi":"10.1093/ehjdh/ztaf052","DOIUrl":"10.1093/ehjdh/ztaf052","url":null,"abstract":"","PeriodicalId":72965,"journal":{"name":"European heart journal. Digital health","volume":"6 4","pages":"527-528"},"PeriodicalIF":3.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12282357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}