Ivan L. Volkov, Zahra Khaji, Magnus Johansson, Maria Tenje
{"title":"A Microfluidic Platform for In Situ Studies of Bacteria Electroporation (Adv. Mater. Technol. 4/2025)","authors":"Ivan L. Volkov, Zahra Khaji, Magnus Johansson, Maria Tenje","doi":"10.1002/admt.202570018","DOIUrl":"https://doi.org/10.1002/admt.202570018","url":null,"abstract":"<p><b>Microfluidic Platforms</b></p><p>Electroporation of bacterial cells is challenging due to their small size and complex cell envelope. In article number 2401177, Magnus Johansson, Maria Tenje, and co-workers present a microfluidic platform for <i>E. coli</i> electroporation with in situ microscopy capability. Real-time observations reveal that electrophoresis plays an important role in a miniaturized platform, but its undesired action can be balanced using bipolar electrical pulses.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 4","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Misagh Rezapour Sarabi, Sara Soltanabadi Farshi, Zeynep Saltik, Saba Khosbakht, Nesimi Buyukbabani, Orhan Agcaoglu, Secil Vural, Metin Sitti, Savas Tasoglu
{"title":"Long-Lasting Simultaneous Epidermal and Dermal Microneedle-Enabled Drug Delivery (Adv. Mater. Technol. 4/2025)","authors":"Misagh Rezapour Sarabi, Sara Soltanabadi Farshi, Zeynep Saltik, Saba Khosbakht, Nesimi Buyukbabani, Orhan Agcaoglu, Secil Vural, Metin Sitti, Savas Tasoglu","doi":"10.1002/admt.202570017","DOIUrl":"https://doi.org/10.1002/admt.202570017","url":null,"abstract":"<p><b>Microneedle-Enabled Drug Delivery</b></p><p>In article number 2400980, Metin Sitti, Savas Tasoglu, and co-workers show that microneedles, well-known for their advantageous drug delivery features, can be engineered into nonlinear designs facilitating simultaneous drug delivery to multiple skin layers or a release mechanism in a long lasting manner. The advanced technology of nonlinear microneedles is helpful for treatment of diseases that manifest at varying depths of skin.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 4","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multi Computer Vision-Driven Testing Platform: Structural Reconstruction and Material Identification with Ultrabroadband Carbon Nanotube Imagers","authors":"Daiki Shikichi, Raito Ota, Miki Kubota, Yuya Kinoshita, Noa Izumi, Mitsuki Kosaka, Tomoki Nishi, Daiki Sakai, Yuto Matsuzaki, Leo Takai, Minami Yamamoto, Yuto Aoshima, Ryoga Odawara, Takeru Q. Suyama, Hiroki Okawa, Zhenyu Zhou, Tomoya Furukawa, Shota Wada, Satoshi Ikehata, Imari Sato, Yukio Kawano, Kou Li","doi":"10.1002/admt.202401724","DOIUrl":"https://doi.org/10.1002/admt.202401724","url":null,"abstract":"<p>While non-destructive inspections of daily necessities and industrial products require material composition identifications and structural reconstructions of composite multi-layered 3D objects, the development of analyzing systems that fully satisfy those performances is still insufficient. For such situations, this work synergizes permeable material identifications with carbon nanotube (CNT) film photo-thermoelectric (PTE) imagers in millimeter-wave (MMW)–visible light (Vis) bands and conventional Vis-computer vision (CV) approaches mainly used for analyzing outer shapes of 3D objects. Specifically, this work demonstrates multi-CV-driven non-destructive structural reconstruction techniques by ultrabroad MMW–Vis band multi-wavelength optical monitoring using the CNT film PTE imager. Here, the CNT film PTE imager ultra-broadly performs photo-detection operations over the existing sensors in comparable sensitivities with the conventional narrowband devices at each region. Thus, the above imager facilitates utilizing ultrabroadband multi-wavelength photo-irradiation as playing an essential role in the presenting non-destructive CV system. Following such device performances, the MMW–Vis multi-CV system with the CNT film PTE imager first speculates spatial locations of each part for targets by visual hull measurements, then restores their detailed structures by tomography approaches. By incorporating these device and system properties, this work finally achieves non-destructive composition-identifying structural reconstructions for composite multi-layered 3D objects.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 7","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202401724","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teerapat Lapsirivatkul, Roman Strauss, Chuchawin Changtong, Thasanaporn Ungpittagul, Thanadporn Tanasaro, Jidapa Chaopaknam, Daniel Crespy, Pichaya Pattanasattayavong
{"title":"A Polymer Composite as a Thermal Antifuse for Battery-free RFID Temperature Indicators","authors":"Teerapat Lapsirivatkul, Roman Strauss, Chuchawin Changtong, Thasanaporn Ungpittagul, Thanadporn Tanasaro, Jidapa Chaopaknam, Daniel Crespy, Pichaya Pattanasattayavong","doi":"10.1002/admt.202401499","DOIUrl":"https://doi.org/10.1002/admt.202401499","url":null,"abstract":"<p>Time-temperature indicators (TTIs) play an important role in logistics, supply chain, and inventory management. They indicate a visual signal when the temperature exceeds a predefined threshold. However, TTIs require a manual process of checking each label individually, making their applications time and cost-intensive. Radio frequency identification (RFID) tags can streamline the process with data readily available in digital format. Challenges of RFID-based temperature sensors are the need for a battery and incompatibility with standard readers. In this study, thermoresponsive composites are developed based on acetylene black (AB) and poly(ethylene glycol) (PEG). By mixing two PEG binders having different molecular weights, the resulting composites function as thermal antifuses, irreversibly transitioning from a high resistance (HR) state to a low resistance (LR) state. The optimal composition detects a threshold temperature of ≈60 °C and shows a large HR/LR ratio of >10<sup>3</sup>. Combining the antifuse based on this unique AB/PEG composite with an RFID tag with a tamper detection capability allows the fabrication of a battery-free, passive RFID temperature indicator equipped with a 1-bit non-volatile memory. The device can track the environment of temperature-sensitive items, save the status, and indicate a digital output when a temperature threshold has been exceeded.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 9","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Edible Jumpers Powered by Shell Snapping","authors":"Bokeon Kwak, Juliette Hars, Dario Floreano","doi":"10.1002/admt.202401230","DOIUrl":"https://doi.org/10.1002/admt.202401230","url":null,"abstract":"<p>Food animation is gaining increasing attention for the ability to reduce waste and increase attractiveness in animals and humans. Although several examples of food animation methods have been recently described, the speed and range of motion are still limited. Here a method is described to design and manufacture small edible jumpers powered by rapid release of elastic energy through shell snapping. The jumping actuators are made of gelatin crosslinked with genipin and polyvinyl alcohol, ensuring resilience to stress during shell eversion. The shape and size of the shells are modeled and optimized for maximum jumping height resulting in jumpers with a diameter of 47 mm that can reach a jumping height of 361 mm. The edible jumpers can be loaded with additional nutritional components encapsulated by humidity-sensitive latches for automatic release. To showcase potential uses of such edible jumpers, a jumping food pellet for pets and an animated dessert for humans are described.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 8","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202401230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten
{"title":"An Injection-Molded Modified Silicone Rubber for Cancer-on-Chip Applications","authors":"Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten","doi":"10.1002/admt.202401450","DOIUrl":"https://doi.org/10.1002/admt.202401450","url":null,"abstract":"<p>For drug screening and personalized medicine approaches, cancer-on-chip (CoC) models are valuable as these systems enable precise control of cellular and tissue architecture and can be equipped with micro-sensors for real-time monitoring of physiological responses to drugs. Accurate design of the microfluidic device is important to allow recapitulation of key factors of a tumor and its microenvironment. Polydimethylsiloxane (PDMS) is widely used as material for microfluidics due to its favorable characteristics including low cost, suitability for rapid prototyping, optical transparency, and biocompatibility. However, the hydrophobic nature of PDMS complicates its use in microfluidic devices. Here, the characterization and application of an injection-molded functionalized PDMS fluidic insert for the commercially available Micronit system are described. The injection-molded PDMS has been modified with carboxyl groups to accommodate cell culture on its surface and to covalently bind proteins for long-lasting coating of the PDMS surface required for flow-conditions. Modification of PDMS does not change its favorable properties such as its high optical transparency and absence of auto-fluorescence. The modified PDMS fluidic inserts are suitable for building relevant cancer models on chip and do not show absorption of small molecules such as doxorubicin, allowing their use for drug screening and personalized medicine approaches on chip.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202401450","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143638798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Jouybar, Sophie van der Kallen, Sheen Sahebali, Carlijn Bouten, Jaap M.J. den Toonder
{"title":"The Impact of Channel Geometry and Flow Regime on Endothelial Orientation and Morphology in Vessel-on-Chip","authors":"Mohammad Jouybar, Sophie van der Kallen, Sheen Sahebali, Carlijn Bouten, Jaap M.J. den Toonder","doi":"10.1002/admt.202401994","DOIUrl":"https://doi.org/10.1002/admt.202401994","url":null,"abstract":"<p>This study investigates the impact of channel geometry and applied flow on the orientation and morphology of endothelial cells (ECs) within vessel-on-chip (VoC) models. Traditional organ-on-chip models often utilize rectangular cross-section channels, resulting in flat walls, sharp corners, and non-uniform wall shear stress profiles, which do not accurately mimic physiological conditions. Tubular channels with circular cross-sections provide a more in vivo-like geometry and result in a physiological uniform wall shear stress. Here, tubular channels fabricated using sugar 3D-printing are compared with rectangular channels made via stereolithography 3Dprinting. The results show that ECs from both blood and lymph vessels exhibit more uniform coverage and circumferential alignment in tubular channels than in rectangular channels. Unidirectional or bidirectional flow conditions align ECs parallel to the flow, overruling the circumferential alignment induced by curvature in tubular channels. Pulsatile flow enhances circumferential orientation in tubular channels, while alignment along the flow is maintained in rectangular channels. Additionally, EC orientation induced by flow impacts monocyte rolling velocities, crucial for understanding immune cell motility. This study underlines the importance of the combined effect of channel geometry and flow conditions in VoC models, and advocates for the continued development of advanced organ-on-chip systems that better replicate human physiology.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 7","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202401994","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Torge Hartig, Joschka Paulsen, Jonas Drewes, Asmaa T. Mohamed, Nasra F. Abdel Fattah, Cedric Hinrichs, Felix Pohl, Stefan Rehders, Ainura Aliyeva, Henning Wieker, Jörg Wiltfang, Salih Veziroglu, Samah A Loutfy, Oral Cenk Aktas, Alexander Vahl, Thomas Strunskus, Aydin Gülses, Amal Amin, Stefan Schröder, Franz Faupel
{"title":"Functional Polymer Nanocomposites by Gas Aggregation Cluster Source and Initiated Chemical Vapor Deposition","authors":"Torge Hartig, Joschka Paulsen, Jonas Drewes, Asmaa T. Mohamed, Nasra F. Abdel Fattah, Cedric Hinrichs, Felix Pohl, Stefan Rehders, Ainura Aliyeva, Henning Wieker, Jörg Wiltfang, Salih Veziroglu, Samah A Loutfy, Oral Cenk Aktas, Alexander Vahl, Thomas Strunskus, Aydin Gülses, Amal Amin, Stefan Schröder, Franz Faupel","doi":"10.1002/admt.202401763","DOIUrl":"https://doi.org/10.1002/admt.202401763","url":null,"abstract":"<p>Functional metal-polymer nanocomposites are required for highly tailored surface properties and coatings. However, past approaches like cosputtering, physical evaporation, or plasma polymerization can not retain the functionality of the polymer matrix or produce tailored nanoparticles. A new kind of codeposition of nanocomposite polymer thin films is presented via the combination of a <i>gas aggregation cluster source (GAS)</i> and <i>initiated chemical vapor deposition (iCVD)</i> in a common GAS+iCVD vacuum system. iCVD delivers ultraprecise and defect-free polymer thin films on the nanoscale while a GAS creates nanoparticles that form in the gas phase and can be tuned in size and composition. Using the GAS+iCVD system, nanocomposites of well-defined Ag nanoparticles in a chemically intact PTFE polymer thin film are prepared. The deposited nanocomposite proved applicable in antibacterial applications by decreasing the colony-forming units of <i>Enterococcus faecalis</i> by 38%. Antiviral SARS-CoV-2 Spike-ACE-2 binding inhibition reaches 65% of pure silver nanoparticles. The nanocomposite improves the apoptotic gene expression for liver cancer cells compared to pure thin films. This new kind of codeposition paves the way for the fabrication of functional nanocomposite thin films combining the advantages of the iCVD polymer palette with a large variety of nanoparticles that can be prepared by GAS.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 9","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202401763","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saliha Mutlu, Bülend Ortaç, Ali Karatutlu, Taylan Gorkan, Engin Durgun, Dilek Söyler, Saniye Söylemez, Nergis Arsu, Sevil Savaskan Yılmaz
{"title":"Engineering of the High-Power Laser-Induced Synthesis of Ni-Based Metal-Organic Framework: Investigation of its Optical Properties, Computational Methodology, Electrocatalytic Performances, and Glucose-Sensing Ability (Adv. Mater. Technol. 3/2025)","authors":"Saliha Mutlu, Bülend Ortaç, Ali Karatutlu, Taylan Gorkan, Engin Durgun, Dilek Söyler, Saniye Söylemez, Nergis Arsu, Sevil Savaskan Yılmaz","doi":"10.1002/admt.202570014","DOIUrl":"https://doi.org/10.1002/admt.202570014","url":null,"abstract":"<p><b>Ni-Based Metal-Organic Frameworks</b></p><p>In article number 2401245, Bülend Ortaç, Engin Durgun, Saniye Söylemez, Nergis Arsu, Sevil Savaskan Yilmaz, and co-workers present the unprecedented high-power laser-induced rapid synthesis (LIRS) of Ni-based MOF nanospheres with interconnected nano-rods and noncentrosymmetric primitive triclinic crystalline structure; due to a large amount of electrochemical active sites for the oxidation of glucose, the glucose levels within real-life beverages is applied to investigate the low limit of the detection and high sensitivity. \u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143111802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yifan You, Chen Dai, Ezequiel Goldschmidt, Ronald S. Fearing
{"title":"Multi-Layer LDPE Pouch Robots Enabled by Inkjet-Printed Masking Layers (Adv. Mater. Technol. 3/2025)","authors":"Yifan You, Chen Dai, Ezequiel Goldschmidt, Ronald S. Fearing","doi":"10.1002/admt.202570013","DOIUrl":"https://doi.org/10.1002/admt.202570013","url":null,"abstract":"<p><b>LDPE Pouch Robots</b></p><p>In article number 2401052, Yifan You, Ronald S. Fearing, and co-workers create soft inflatable pouch robots with many independent degrees of freedom from multiple layers of 38 micron thermoplastic films. This new fabrication method uses inkjet-printed solvent ink to pattern pouch layers, enabling the integration of pouch actuators, structures, channels, and pneumatic ports within one process. Application examples include a 4-finger 8-independent-DoF pouch hand performing in-hand manipulation, and a 10-independent-DoF continuum manipulator performing planar pick-and-place.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 3","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143111801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}