{"title":"Silicon Photonics for Co-Packaged Optics: A Review of Core PIC Components and Industry Strategies","authors":"Ying Zhang, Xiangsheng Wang, Zhenzhen Kong, Yiwen Zhang, Yanpeng Song, Hailing Wang, Xiaomeng Liu, Siqi Zhao, Guilei Wang, Chao Zhao","doi":"10.1002/admt.71266","DOIUrl":"https://doi.org/10.1002/admt.71266","url":null,"abstract":"<div>\u0000 \u0000 <p>Co-packaged optics (CPO) has emerged as a pivotal technology for overcoming the bandwidth, power, and scalability bottlenecks of next-generation AI and data center interconnects by closely integrating the optical engine (OE) with electronic chips (e.g., ASICs and XPUs). As a key component of the OE, photonic integrated circuits (PIC) are predominantly realized on the silicon photonics (SiPh) platform, which provides CMOS-compatible fabrication, scalable heterogeneous integration, and the capability to implement full photonic functionalities on chip. Thus, this review presents a comprehensive overview of recent advances in core device-level components of SiPh-based PIC, including laser sources, Si-based modulators, passive optical couplers, Ge-on-Si photodetectors, and multiplexers/demultiplexers, which significantly impact the performance of CPO systems. Industry strategies and representative system-level demonstrations are also summarized to depict the current technological landscape. Furthermore, critical challenges and potential solutions for CPO system development are discussed, such as laser integration, thermal management, device reliability, bandwidth density, and energy efficiency. Together, these insights offer a device-level roadmap for advancing CPO toward scalable, high-performance, and economically viable deployment.</p>\u0000 </div>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-Speed Broadband Self-Powered Photodetectors Based on Tin Sulfide/Graphitic Carbon Nitride Composites for Environmental Monitoring","authors":"Bhavasree Sreedhar, Nivin Thulasibai Sasidharan, Arbacheena Bora, Karthigeyan Annamalai, Yuvaraj Sivalingam, Elangovan Elamurugu","doi":"10.1002/admt.71237","DOIUrl":"https://doi.org/10.1002/admt.71237","url":null,"abstract":"<div>\u0000 \u0000 <p>Developing photodetectors with rapid response, broad spectral coverage, and self-powered operation remains a major challenge since they are mutually exclusive. This challenge is tackled by compositing tin sulfide (SnS) and graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>) through a controlled incorporation of g-C<sub>3</sub>N<sub>4</sub> (0.5–15 wt.%), to modulate depletion width, band alignment, and surface defects. The optimized composite (1 wt.% g- C<sub>3</sub>N<sub>4</sub>, named SG-1) exhibits broadband absorption spanning 250–1400 nm, a strong zero-bias photocurrent (2.24 µA), and rapid rise/decay times of 0.48/0.47 ms, which are among the fastest reported for SnS-based photodetectors. Scanning Kelvin probe (SKP) analysis reveals a pronounced illumination-induced work-function modulation (ΔWF ≈ 0.23 eV), confirming enhanced built-in field and reduced surface defect density. Correspondingly, SG-1 achieves a responsivity of 2.8 mA/W and a detectivity of 1.9 × 10<sup>9</sup> Jones that is ∼4× greater than pristine SnS. The combined optical, electrical, and contact potential difference (CPD) establishes that g-C<sub>3</sub>N<sub>4</sub>-driven depletion modulation is instrumental for rapid carrier dynamics. These results validate SnS/g-C<sub>3</sub>N<sub>4</sub> composites as promising candidates for next-generation ultrabroadband, low-power, and high-speed photodetectors for environmental sensing, optical communication, and IoT-integrated systems.</p>\u0000 </div>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sri Vaishnavi Thummalapalli, Dhanush Patil, Libin Yang, M. Taylor Sobczak, Anshul Kulkarni, Xiao Sun, Arunachalam Ramanathan, Tiantian Li, Ramaraja P. Ramasamy, Jason J. Locklin, Yanyu Chen, Xianqiao Wang, Arunachala Mada Kannan, Kenan Song
{"title":"Advanced Manufacturing of Composite-Based Systems for Energy Applications","authors":"Sri Vaishnavi Thummalapalli, Dhanush Patil, Libin Yang, M. Taylor Sobczak, Anshul Kulkarni, Xiao Sun, Arunachalam Ramanathan, Tiantian Li, Ramaraja P. Ramasamy, Jason J. Locklin, Yanyu Chen, Xianqiao Wang, Arunachala Mada Kannan, Kenan Song","doi":"10.1002/admt.71173","DOIUrl":"https://doi.org/10.1002/admt.71173","url":null,"abstract":"<p>Electrochemical energy devices are increasingly expected to deliver high energy and power density while also meeting requirements for safety, mechanical compliance, geometric freedom, and tight integration with sensing and control electronics. In most commercial platforms, however, these functions remain compartmentalized as electrodes and electrolytes are engineered primarily for electrochemical performance, while thermal management, gas mitigation, and diagnostics are appended as external layers or separate circuitry. This separation constrains coupled optimization of charge, heat, and mass transport, limiting the development of truly multifunctional, form-factor–agnostic systems. This review adopts a materials-centric hybrid-manufacturing perspective to evaluate how additive manufacturing (AM) can overcome these constraints. We survey AM methods relevant to energy technologies such as material extrusion, electrohydrodynamic/electrostatic printing, and coating approaches that bridge conventional slurry processing with architected three-dimensional constructs. We then examine key material families through printability–function linkages, including polymers, ceramics, metal oxides, and composites for ion transport, thermal regulation, solid-state protection, and embedded sensing. Finally, distill microstructural design principles connecting voxel-scale architectures to transport, percolation/tunneling networks, tortuosity and connectivity control, stimuli-responsive pathways, and multimaterial/gradient interfaces—highlight case studies and remaining challenges in precision, compatibility, and scale-up.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.71173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technologies for Natural-Synthetic Polymer Hybrids: Synergistic Biointerface Engineering From Fabrication to Devices","authors":"Ronghao Mo, Yinglei Wu, Zhongyi He, Sirui Wang","doi":"10.1002/admt.71239","DOIUrl":"https://doi.org/10.1002/admt.71239","url":null,"abstract":"<div>\u0000 \u0000 <p>This review summarizes natural and synthetic polymer hybrid materials for biointerface engineering. Natural polymers like chitosan, collagen, and hyaluronic acid (HA) provide biocompatibility and bioactivity but lack mechanical strength, whereas synthetic polymers such as polylactic acid, polycaprolactone, and polyethylene glycol offer tunable mechanical properties yet lack bioactive sites. Integrating these via physical blending, covalent functionalization, layer-by-layer assembly, block/graft copolymer design, in situ synthesis, and topographical patterning creates synergistic effects. These include balanced mechanical and biological performance, stimuli-responsiveness to pH, temperature, enzymes, and magnetic fields, combined antifouling and targeting functions, immunomodulation, and multifunctional integration. Key applications encompass tissue engineering scaffolds, spatiotemporally controlled drug delivery, advanced biosensing, antimicrobial coatings, and organ-on-a-chip platforms. Despite progress, challenges persist regarding natural polymer batch-to-batch variability, potential toxicity of synthetic degradation byproducts, long-term stability, scalability of manufacturing, and clinical translation. Future research should prioritize multi-responsive intelligent materials, AI-driven design, green manufacturing, and interdisciplinary collaboration to standardize evaluation criteria and accelerate clinical use in regenerative medicine, personalized theranostics, and implantable electronics.</p>\u0000 </div>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yash V. Ambole, Kasturi A. Rokade, Sumedh S. Mahajan, Dhananjay D. Kumbhar, Sujal B. Kale, Parth S. Thorat, Santosh S. Sutar, Aruna G. Bhosale, Tae Geun Kim, Sharadrao A. Vanalakar (Vhanalkar), Tukaram D. Dongale
{"title":"Brain-Like Computing Using CuInS2 Quantum Dots: A Synergy of Materials, Devices, and Machine Learning Modeling","authors":"Yash V. Ambole, Kasturi A. Rokade, Sumedh S. Mahajan, Dhananjay D. Kumbhar, Sujal B. Kale, Parth S. Thorat, Santosh S. Sutar, Aruna G. Bhosale, Tae Geun Kim, Sharadrao A. Vanalakar (Vhanalkar), Tukaram D. Dongale","doi":"10.1002/admt.71210","DOIUrl":"https://doi.org/10.1002/admt.71210","url":null,"abstract":"<div>\u0000 \u0000 <p>The advanced artificial intelligence applications demand new computing paradigms that can mimic the brain's processing capabilities. Chalcogenide-based quantum dots (QDs) possess excellent chemical stability and electrical properties, emerging as promising candidates for neuromorphic devices. In this work, we have developed CuInS<sub>2</sub> QDs (CIS QDs) based resistive switching (RS) devices for non-volatile memory and neuromorphic computing applications. The CIS QDs-based RS device can switch at +1.15 V (V<sub>SET</sub>) and −0.73 V (V<sub>RESET</sub>) and demonstrate good non-volatile memory properties (endurance: 5 × 10<sup>3</sup> cycles and retention: 10<sup>4</sup> s). The switching variability of the device was modeled, predicted, and forecasted by using multivariate time series and machine learning techniques. Additionally, the CIS QD-based RS device has mimicked various forms of synaptic learning functions such as potentiation, depression, excitatory post-synaptic current, and inhibitory post-synaptic current. Moreover, the multilayer perceptron neural network was implemented to demonstrate the handwritten digits classification ability of the CIS QDs-based RS device. These results demonstrate the potential of CIS QDs for next-generation neuromorphic computing hardware.</p>\u0000 </div>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microfabrication of Soft Millirobots Propelled by Low Voltage Electrohydraulic Actuators","authors":"Shai Shmulevich, Florian Hartmann, Herbert Shea","doi":"10.1002/admt.71249","DOIUrl":"https://doi.org/10.1002/admt.71249","url":null,"abstract":"<p>Micron- and millimeter-scale soft actuators with high energy density and rapid response are an essential step toward highly functional untethered millirobots. Scaling down electrohydraulic actuators, such as HASELs, from cm-scale to mm-scale requires a complete change in manufacturing methods, switching from laser patterning and film lamination to MEMS-like cleanroom processes. Here, we introduce a versatile wafer-level microfabrication strategy for soft electrohydraulic actuators at the millimeter and sub-mm scales. Scaling down such actuators leads to thinner films and hence to lower drive voltages but requires adapting MEMS processes optimized for rigid materials to be compatible with the polymers and liquid-filled cavities needed for electrohydraulics. Our wafer-level process integrates Parylene-sealed mm-long microcavities into multilayer architectures from flexible µm-thick polymer–metal layers. The resulting actuators operate below 300 volts, a substantial reduction from the 1–5 kV typical of similar macro-scale actuators. This microfabrication approach enables monolithic integration of actuators in robots, combining repeatability and precision. We realized a 20 × 20 mm<sup>2</sup> sized swimming robot incorporating two embedded actuators to drive a pair of pectoral fins. This work establishes a pathway toward untethered electrohydraulic robots at millimeter scale and below.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.71249","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MD Redowan Mahmud Arnob, Solbee Lee, Hansol Jeong, Sabiqun Nahar, Jin Jang
{"title":"O Radical-Induced n-to-p Transition in PbS Quantum Dots Enabling Enhanced and Stable Photogating in QD/IGZO SWIR Phototransistors","authors":"MD Redowan Mahmud Arnob, Solbee Lee, Hansol Jeong, Sabiqun Nahar, Jin Jang","doi":"10.1002/admt.71234","DOIUrl":"https://doi.org/10.1002/admt.71234","url":null,"abstract":"<p>Colloidal PbS quantum dots (QDs) are promising photosensitizers for short-wave infrared phototransistors. But their photogating efficiency is limited by unfavorable energy band alignment and interfacial defects. Here, we report an O radical exposure to induce an effective n-to-p transition in PbS QDs using atmospheric Ar/O<sub>2</sub> plasma (AAP). This leads to enhanced and stable photogating effect in PbS QD/IGZO phototransistors. Ultraviolet photoelectron spectroscopy (UPS) results show the work‑function increase from 4.10 to 4.47 eV and the shift of E<sub>F</sub> toward mid‑gap, E<sub>C</sub><sup>−</sup>E<sub>F</sub> shifts from 0.26 to 0.65 eV by 15 cycles of AAP treatment. The XPS results indicate the increase of M─O from 44.9% to 81.1%, and the decrease in oxygen vacancies (V<sub>O</sub>) from 38.8% to 16.1%, and hydroxyl (─OH) concentration from 16.3% to 2.8% at the interface by AAP. These modifications suppress off-state current (I<sub>off</sub>), shift threshold voltage (V<sub>TH</sub>) to positive, minimize interface trap density (D<sub>it</sub>), and suppress photocurrent decay, thereby stabilizing photogating effect. The AAP-treated device shows the responsivity 2883 A W<sup>−</sup><sup>1</sup>, detectivity 7.43 × 10<sup>1</sup><sup>3</sup> Jones, and EQE 2.75 × 10<sup>5</sup>% at 1300 nm under 1 mW cm<sup>−2</sup>. A 5 × 5 pattern recognition array based on PbS QD/IGZO phototransistors shows alphanumeric patterns under SWIR illumination.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.71234","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elisabeth Erbes, Naireeta Biswas, Calvin J. Gavillet, Matthias Schwartzkopf, Krishnayan Basuroy, Qing Chen, Andrei Chumakov, Susann Frenzke, Marc Gensch, Korneliya Gordeyeva, Patrycja Kielb, Sonja Kirchner, Volker Körstgens, Peter Müller-Buschbaum, Henrike M. Müller-Werkmeister, Jan Rubeck, Sreevidya Thekku Veedu, Jose de Jesus Velazquez-Garcia, Vivian Waclawek, Daniel Söderberg, Stephan V. Roth, Simone Techert
{"title":"Hydro- and Lipophilicity of Molecular-Size-Controlled Hydrogel Drug Carriers (Adv. Mater. Technol. 20/2026)","authors":"Elisabeth Erbes, Naireeta Biswas, Calvin J. Gavillet, Matthias Schwartzkopf, Krishnayan Basuroy, Qing Chen, Andrei Chumakov, Susann Frenzke, Marc Gensch, Korneliya Gordeyeva, Patrycja Kielb, Sonja Kirchner, Volker Körstgens, Peter Müller-Buschbaum, Henrike M. Müller-Werkmeister, Jan Rubeck, Sreevidya Thekku Veedu, Jose de Jesus Velazquez-Garcia, Vivian Waclawek, Daniel Söderberg, Stephan V. Roth, Simone Techert","doi":"10.1002/admt.71391","DOIUrl":"https://doi.org/10.1002/admt.71391","url":null,"abstract":"<p><b>Therapeutic Nanopaper</b></p><p>Smart wound-healing patches with defined nanoproperties embed both lipophilic and hydrophilic drugs in the same cellulose/peptide hydrogels thereby enabling the delivery of complementary drugs at one wound site. Real-time growth tracked via pulsed X-ray sources also makes these hydrogels a tool for drug analysis. See Research Article e71285 by Stephan V. Roth, Simone Techert and co-workers for more details.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.71391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On-Demand Sweat Stimulation and Visual Quantification of Chloride via a Wearable Integrated Paperfluidic Sensor for Resource-Limited Cystic Fibrosis Screening","authors":"Prakhar Singh, Aaryan Sood, Vibhav Katoch, Abhishek Kumar, Bhanu Prakash","doi":"10.1002/admt.71058","DOIUrl":"https://doi.org/10.1002/admt.71058","url":null,"abstract":"<div>\u0000 \u0000 <p>Sweat-based diagnostics offer a non-invasive and accessible method for real-time health monitoring, enabling direct assessment of physiological and biochemical markers from the skin without the complexity of conventional sampling. In this study, we present a wearable paper-based sensor that enables colorimetric detection of chloride ions in sweat for cystic fibrosis (CF) screening. Unlike conventional wearable CF sensors that require complex fabrication and sophisticated instrumentation, our low-cost, disposable device integrates a hydrophobically patterned paper substrate with an overlaid paper-fluidic channel impregnated with a chloride-sensitive reagent for direct visual quantification of Cl<sup>−</sup> levels. To facilitate efficient sweat stimulation, we developed an iontophoresis system that delivers controlled electrical current to stimulate localized sweat secretion, with an Arduino-based module integrated for real-time monitoring of output current and elapsed time. The device was validated with artificial sweat for chloride quantification and tested on human volunteers to demonstrate effectiveness in sweat stimulation and collection. The sensor exhibited a clinically relevant detection range, with strong correlation between color intensity and chloride concentration, confirming accuracy and reliability for CF diagnostics. By combining low-cost fabrication, on-demand sweat stimulation, and colorimetric analysis, this instrument-free, wearable platform presents a promising alternative to traditional testing for point-of-care diagnostics in resource-constrained healthcare settings.</p>\u0000 </div>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim
{"title":"3D-Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress","authors":"Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim","doi":"10.1002/admt.71162","DOIUrl":"https://doi.org/10.1002/admt.71162","url":null,"abstract":"<p>The cornea is a highly complex, transparent tissue, serving the critical role of focusing the light onto the retina. Due to global shortage of healthy donor corneas for transplantation, there is an urgent need for alternative strategies to restore corneal function in diseased or injured corneal cases. This demand has pushed researchers to develop synthetic tissue-engineered corneas. In this context, three-dimensional (3D) printing technologies have recently drawn significant attention due to their ability to fabricate complex, patient-specific structures with various shapes and architectures, making them an interesting option for the fabrication of artificial corneal tissue. To date, numerous studies have focused on the fabrication and in vitro characterization of 3D-printed corneal substitutes, but fewer of them have evaluated their therapeutic efficacy in vivo. This paper aims to provide a focused evaluation of the in vivo outcomes of synthetic corneal implants fabricated using various 3D-printing techniques and materials. We also highlight current challenges and potential future directions for 3D printing of corneal substitutes.</p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"11 20","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.71162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149235295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}