Transcript Identification Using Arrayed Hydrogels With TrapFISH (Adv. Mater. Technol. 18/2025)

IF 6.4 3区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Materials Technologies Pub Date : 2025-09-17 DOI:10.1002/admt.70330

David B. Morse, Zenon Toprakcioglu, Akhila Denduluri-Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles

引用次数: 0

Abstract

Single-cell Transcript Quantification

On the cover, an artistic rendering highlights single-cell transcript quantification using microfluidic traps. In their Research Article (10.1002/admt.202401953), Tuomas P. J. Knowles and co-workers introduce, trapFISH, a method where individual cells are encapsulated in hydrogel beads, arrayed in microfluidic traps, and analyzed for transcript abundance through fluorescent hybridization and enzyme-free signal amplification. Original artwork by David B. Morse.

Abstract Image

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利用TrapFISH （Adv. Mater）阵列水凝胶鉴定转录本。抛光工艺。18/2025)

单细胞转录定量在封面上，艺术渲染突出单细胞转录定量使用微流体陷阱。在他们的研究论文（10.1002/admt）中。202401953), Tuomas p.j. Knowles及其同事介绍了trapFISH，这是一种将单个细胞包裹在水凝胶珠中，在微流体陷阱中排列，并通过荧光杂交和无酶信号放大分析转录物丰度的方法。大卫·b·莫尔斯的原创作品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Materials Technologies Materials Science-General Materials Science

CiteScore

10.20

自引率

4.40%

发文量

566

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