利用TrapFISH （Adv. Mater）阵列水凝胶鉴定转录本。抛光工艺。18/2025)

IF 6.4 3区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Materials Technologies Pub Date : 2025-09-17 DOI:10.1002/admt.70330

David B. Morse, Zenon Toprakcioglu, Akhila Denduluri-Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles

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引用次数: 0

摘要

单细胞转录定量在封面上，艺术渲染突出单细胞转录定量使用微流体陷阱。在他们的研究论文（10.1002/admt）中。202401953), Tuomas p.j. Knowles及其同事介绍了trapFISH，这是一种将单个细胞包裹在水凝胶珠中，在微流体陷阱中排列，并通过荧光杂交和无酶信号放大分析转录物丰度的方法。大卫·b·莫尔斯的原创作品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Transcript Identification Using Arrayed Hydrogels With TrapFISH (Adv. Mater. Technol. 18/2025)

查看原文本刊更多论文

Transcript Identification Using Arrayed Hydrogels With TrapFISH (Adv. Mater. Technol. 18/2025)

Single-cell Transcript Quantification

On the cover, an artistic rendering highlights single-cell transcript quantification using microfluidic traps. In their Research Article (10.1002/admt.202401953), Tuomas P. J. Knowles and co-workers introduce, trapFISH, a method where individual cells are encapsulated in hydrogel beads, arrayed in microfluidic traps, and analyzed for transcript abundance through fluorescent hybridization and enzyme-free signal amplification. Original artwork by David B. Morse.

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来源期刊

Advanced Materials Technologies Materials Science-General Materials Science

CiteScore

10.20

自引率

4.40%

发文量

566

期刊介绍： Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.